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Open Access research that better understands changing marine ecologies...

Strathprints makes available scholarly Open Access content by researchers in the Department of Mathematics & Statistics.

Mathematics & Statistics hosts the Marine Population Modelling group which is engaged in research into topics surrounding marine resource modelling and ecology. Recent work has included important developments in the population modelling of marine species.

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Number of items: 187.

2024

Alanazi, S. and Doonan, J. and Lumb, F. E. and Alenzi, N. and Jabbar, S. and Al-Riyami, L. and Suckling, C. J. and Harnett, W. and Watson, D. G. (2024) Reduction in creatine metabolites in macrophages exposed to small molecule analogues of the anti-inflammatory parasitic worm product ES-62. Parasite Immunology, 46 (2). e13026. ISSN 0141-9838

2023

Abbas, Muhammad and Alossaimi, Manal A. and Altamimi, Abdulmalik S. A. and Alajaji, Mai and Watson, David G. and Shah, Sayyed I. and Shah, Yasar and Anwar, Mohammad S. (2023) Determination of α1-acid glycoprotein (AGP) concentration by HPLC in patients following local infiltration analgesia for primary total hip arthroplasty and its relation to ropivacaine (total and unbound). Frontiers in Pharmacology, 14. 1145962. ISSN 1663-9812

Alanazi, Ibrahim M. and Alzahrani, Abdullah R. and Zughaibi, Torki A. and Al-Asmari, Ahmed I. and Tabrez, Shams and Henderson, Catherine and Watson, David and Grant, Mary Helen (2023) Metabolomics analysis as a tool to measure cobalt neurotoxicity : an in vitro validation. Metabolites, 13 (6). 698. ISSN 2218-1989

Abu-Izneid, Tareq and Abbas, Muhammad and Watson, David G. and Shah, Yasar and Shah, Sayyed I. and Khuda, Fazli (2023) Estimation of dihydroartemisinin in human plasma using a highly sensitive LTQ orbitrap mass spectrometer with Xcalibur software. Frontiers in Pharmacology, 14. 1157604. ISSN 1663-9812

Ali, Ali Muhsen and Monaghan, Chris and Muggeridge, David J. and Easton, Chris and Watson, David G. (2023) LC/MS-based discrimination between plasma and urine metabolomic changes following exposure to ultraviolet radiation by using data modelling. Metabolomics, 19 (2). 13. ISSN 1573-3882

Alenezi, Samya S. and Alenezi, Naif D. and Ebiloma, Godwin U. and Natto, Manal J. and Ungogo, Marzuq A. and Igoli, John O. and Ferro, Valerie A. and Gray, Alexander I. and Fearnley, James and Koning, Harry P. de and Watson, David G. (2023) The activity of red Nigerian propolis and some of its components against Trypanosoma brucei and Trypanosoma congolense. Molecules, 28 (2). 622. ISSN 1420-3049

2022

Abdullah, Mahmud O. and Zeng, Run X. and Margerum, Chelsea L. and Papadopoli, David and Monnin, Cian and Punter, Kaylee B. and Chu, Charles and Al-Rofaidi, Mohammad and Al-Tannak, Naser F. and Berardi, Domenica and Rattray, Zahra and Rattray, Nicholas J.W. and Abraham, Sheela A. and Eskelinen, Eeva-Liisa and Watson, David G. and Avizonis, Daina and Topisirovic, Ivan and Chan, Edmond Y.W. (2022) Mitochondrial hyperfusion via metabolic sensing of regulatory amino acids. Cell Reports, 40 (7). p. 111198. 111198. ISSN 2211-1247

Patel, Rachana and Ford, Catriona A. and Rodgers, Lisa and Rushworth, Linda K. and Fleming, Janis and Mui, Ernest and Zhang, Tong and Watson, David and Lynch, Victoria and Mackay, Gillian and Sumpton, David and Sansom, Owen J. and Vande Voorde, Johan and Leung, Hing Y. (2022) Cyclocreatine suppresses creatine metabolism and impairs prostate cancer progression. Cancer Research, 82 (14). pp. 2565-2575. ISSN 0008-5472

Igoli, John O. and Teles, Yanna C. F. and Atawodi, Sunday E. and Ferro, Valerie A. and Watson, David G. (2022) Editorial : ethnopharmacological strategies for drug discovery against African neglected diseases. Frontiers in Pharmacology, 13. 851064. ISSN 1663-9812

Alenezi, Samya S. and Alenzi, Naif D. and Ebiloma, Godwin U. and Natto, Manal J. and Ungogo, Marzuq A. and Igoli, John O. and Ferro, Valerie A. and Gray, Alexander I. and Fearnley, James and de Koning, Harry P. and Watson, David G. (2022) The antiprotozoal activity of Papua New Guinea propolis and its triterpenes. Molecules, 27 (5). 1622. ISSN 1420-3049

2021

da Silva Neto, MJJ and MacKay, G and Agaram, R and MacLeod, M and Watson, D G and Thomson, AH (2021) Evaluation of amoxicillin, metronidazole and gentamicin dosage regimens for use in antibiotic prophylaxis in colorectal surgery. Journal of Antimicrobial Chemotherapy, 76 (12). pp. 3212-3219. dkab337. ISSN 0305-7453

Mulvey, Lorna and Wilkie, Stephen E. and Borland, Gillian and Griffiths, Kate and Sinclair, Amy and McGuinness, Dagmara and Watson, David G. and Selman, Colin (2021) Strain-specific metabolic responses to long-term caloric restriction in female ILSXISS recombinant inbred mice. Molecular and Cellular Endocrinology, 535. 111376. ISSN 1872-8057

Alotaibi, Abdullah and Ebiloma, Godwin U. and Williams, Roderick and Alfayez, Ibrahim A. and Natto, Manal J. and Alenezi, Sameah and Siheri, Weam and AlQarni, Malik and Igoli, John O. and Fearnley, James and de Koning, Harry P. and Watson, David G. (2021) Activity of compounds from temperate propolis against Trypanosoma brucei and Leishmania mexicana. Molecules, 26 (13). 3912. ISSN 1420-3049

Alanazi, Samyah and Alenzi, Naif and Alenazi, Fouza and Tabassum, Hajera and Watson, David (2021) Chemical characterization of Saudi propolis and its antiparasitic and anticancer properties. Scientific Reports, 11 (1). 5390. ISSN 2045-2322

Zheoat, Ahmed M. and Alenezi, Samya and Elmahallawy, Ehab Kotb and Ungogo, Marzuq A. and Alghamdi, Ali H. and Watson, David G. and Igoli, John O. and Gray, Alexander I. and de Koning, Harry P. and Ferro, Valerie A. (2021) Antitrypanosomal and antileishmanial activity of chalcones and flavanones from polygonum salicifolium. Pathogens, 10 (2). 175.

Watson, David G. and Pomeroy, Patrick P. and Kennedy, Malcolm W. (2021) Atlantic grey seal milk shows continuous changes in key metabolites and indicators of metabolic transition in pups from birth to weaning. Frontiers in Marine Science, 7. 596904. ISSN 2296-7745

2020

Lotfollahzadeh, Samad and Madadgar, Omid and Reza Mohebbi, Mohammad and Reza Mokhber Dezfouli, Mohammad and Watson, David George (2020) Bovine coronavirus in neonatal calf diarrhoea in Iran. Veterinary Medicine and Science, 6 (4). pp. 686-694. ISSN 2053-1095

Nvau, John B. and Alenezi, Samya and Ungogo, Marzuq A. and Alfayez, Ibrahim A. M. and Natto, Manal J. and Gray, Alexander I. and Ferro, Valerie A. and Watson, David G. and de Koning, Harry P. and Igoli, John O. (2020) Antiparasitic and cytotoxic activity of bokkosin, a novel diterpene-substituted chromanyl benzoquinone from Calliandra portoricensis. Frontiers in Chemistry, 8. 574103. ISSN 2296-2646

Ebiloma, Godwin U. and Ichoron, Nahandoo and Siheri, Weam and Watson, David G. and Igoli, John O. and De Koning, Harry P. (2020) The strong anti-kinetoplastid properties of bee propolis : composition and identification of the active agents and their biochemical targets. Molecules (Basel, Switzerland), 25 (21). 5155. ISSN 1420-3049

Alanazi, Samyah and Alenzi, Naif and Fearnley, James and Harnett, William and Watson, David G. (2020) Temperate propolis has anti-inflammatory effects and is a potent inhibitor of nitric oxide formation in macrophages. Metabolites, 10 (10). 413. ISSN 2218-1989

Watson, David G. and Pomeroy, Patrick P. and Al-Tannak, Naser F. and Kennedy, Malcolm W. (2020) Stockpiling by pups and self-sacrifice by their fasting mothers observed in birth to weaning serum metabolomes of Atlantic grey seals. Scientific Reports, 10 (1). 7465. ISSN 2045-2322

Doig, Craig L. and Zielinska, Agnieszka E. and Fletcher, Rachel S. and Oakey, Lucy A. and Elhassan, Yasir S. and Garten, Antje and Cartwright, David and Heising, Silke and Alsheri, Ahmed and Watson, David G. and Prehn, Cornelia and Adamski, Jerzy and Tennant, Daniel A. and Lavery, Gareth G. (2020) Induction of the nicotinamide riboside kinase NAD+ salvage pathway in a model of sarcoplasmic reticulum dysfunction. Skeletal muscle, 10. 5.

2019

do Nascimento, Ticiano Gomes and dos Santos Arruda, Rodolfo Elleson and da Cruz Almeida, Erika Tayse and dos Santos Oliveira, José Marcos and Basílio-Júnior, Irinaldo Diniz and Celerino de Moraes Porto, Isabel Cristina and Rodrigues Sabino, Adilson and Tonholo, Josealdo and Gray, Alexander and Edrada Ebel, RuAngelie and Clements, Carol and Zhang, Tong and Watson, David George (2019) Comprehensive multivariate correlations between climatic effect, metabolite-profile, antioxidant capacity and antibacterial activity of Brazilian red propolis metabolites during seasonal study. Scientific Reports, 9. pp. 1-16. 18293. ISSN 2045-2322

Miller, Janice and Alshehri, Ahmed and Ramage, Michael I. and Stevens, Nathan A. and Mullen, Alexander B. and Boyd, Marie and Ross, James A. and Wigmore, Stephen J. and Watson, David G. and Skipworth, Richard J.E. (2019) Plasma metabolomics identifies lipid and amino acid markers of weight loss in patients with upper gastrointestinal cancer. Cancers, 11 (10). 1594. ISSN 2072-6694

Alqarni, Abdulmalik M. and Dissanayake, Tharushi and Nelson, David J. and Parkinson, John A. and Dufton, Mark J. and Ferro, Valerie A. and Watson, David G. (2019) Metabolomic profiling of the immune stimulatory effect of eicosenoids on PMA-differentiated THP-1 cells. Vaccines, 7 (4). 142. ISSN 2076-393X

Alghamdi, Abdulaziz and Gray, Alison and Watson, David (2019) Investigation of metabolomics techniques by analysis of MS propolis data : which pre-treatment method is better? Advances and Applications in Statistics, 58 (1). pp. 13-34. ISSN 0972-3617

Alotaibi, Abdullah and Ebiloma, Godwin U. and Williams, Roderick and Alenezi, Samya and Donachie, Anne-Marie and Guillaume, Selome and Igoli, John O. and Fearnley, James and de Koning, Harry P. and Watson, David G. (2019) European propolis is highly active against trypanosomatids including Crithidia fasciculata. Scientific Reports, 9 (1). 11364. ISSN 2045-2322

Iqbal, Muhammad and Fan, Tai-ping and Watson, David and Alenezi, Samya and Saleh, Khaled and Sahlan, Muhamad (2019) Preliminary studies : the potential anti-angiogenic activities of two Sulawesi Island (Indonesia) propolis and their chemical characterization. Heliyon, 5 (7). e01978. ISSN 2405-8440

Svolos, Vaios and Hansen, Richard and Nichols, Ben and Quince, Chrisopher and Ijaz, Umer Z. and Papadopoulou, Rodanthi T. and Edwards, Christine A. and Watson, David and Alghamdi, Adel and Brejnrod, Asker and Ansalone, Cecilia and Duncan, Hazel and Gervais, Lisa and Tayler, Rachel and Salmond, Jonathan and Bolognini, Daniele and Klopfleisch, Robert and Gaya, Daniel R. and Milling, Simon and Russell, Richard K. and Gerasimidis, Konstantinos (2019) Treatment of active Crohn's disease with an ordinary food-based diet that replicates exclusive enteral nutrition. Gastroenterology, 156 (5). pp. 1354-1367. ISSN 0016-5085

Alzahrani, Mansour A. and Alshuwaier, Ghareeb O. and Aljaloud, Khalid S. and Gibson, Colin and Khalaf, Abedawn and Alhawiti, Aliyah S. and Watson, David G. (2019) Development of a derivatization method for investigating testosterone and dehydroepiandrosterone using tandem mass spectrometry in saliva samples from young professional soccer players pre- and post-training. Scientia Pharmaceutica, 87 (2). 11. ISSN 2218-0532

Alqarni, Abdulmalik M. and Niwasabutra, Kanidta and Sahlan, Muhamad and Fearnley, Hugo and Fearnley, James and Ferro, Valerie A. and Watson, David G. (2019) Propolis exerts an anti-inflammatory effect on PMA-differentiated THP-1 cells via inhibition of purine nucleoside phosphorylase. Metabolites, 9 (4). 75. ISSN 2218-1989

Benedetti, Simone and Al-Tannak, Naser F. and Alzharani, Mansour and Moir, Hannah J. and Stensel, David J. and Thackray, Alice E. and Naughton, Declan P. and Dorak, Mehmet T. and Spendif, Owen and Hill, Natasha and Watson, David and Allgrove, Judith (2019) Plasma free fatty acids metabolic profile with LC-MS and appetite-related hormones in South Asian and white European men in relation to adiposity, physical activity and cardiorespiratory fitness : a cross-sectional study. Metabolites, 9 (4). 71. ISSN 2218-1989

Cerone, Michela and Uliassi, Elisa and Prati, Federica and Ebiloma, Godwin U. and Lemgruber, Leandro and Bergamini, Christian and Watson, David G. and de A. M. Ferreira, Thais and Roth Cardoso, Gabriella Simões Heyn and Soares Romeiro, Luiz A. and de Koning, Harry P. and Bolognesi, Maria Laura (2019) Discovery of sustainable drugs for neglected tropical diseases : Cashew Nut Shell Liquid (CNSL)-based hybrids target mitochondrial function and ATP production in Trypanosoma brucei. ChemMedChem, 14 (6). pp. 621-635. ISSN 1860-7179

Alamri, Abdulwahab and Biswas, Lincoln and Watson, David G. and Shu, Xinhua (2019) Deletion of TSPO resulted in change of metabolomic profile in retinal pigment epithelial cells. International Journal of Molecular Sciences, 20 (6). 1387. ISSN 1422-0067

Siheri, Weam and Ebiloma, Godwin U. and Igoli, John O. and Gray, Alexander I. and Biddau, Marco and Akrachalanont, Pilaslak and Samya Sh M D Alenezi, Samya and Alwashih, Mohammad A. and Edrada Ebel, RuAngelie and Müller, Sylke and Lawrence, Catherine E. and Fearnley, James and Watson, David G. and De Koning, Harry P. (2019) Isolation of a novel flavanonol and an alkylresorcinol with highly potent anti-trypanosomal activity from Libyan propolis. Molecules, 24 (6). 1041. ISSN 1420-3049

2018

Alamri, Abdulwahab and Burzangi, Abdulhadi S. and Coats, Paul and Watson, David G. (2018) Untargeted metabolic profiling cell-based approach of pulmonary artery smooth muscle cells in response to high glucose and the effect of the antioxidant vitamins D and E. Metabolites, 8 (4). 87. ISSN 2218-1989

Alghamdi, Adel and Gerasimidis, Konstantinos and Blackburn, Gavin and Akinci, Didem and Edwards, Christine and Russell, Richard K. and Watson, David G. (2018) Untargeted metabolomics of extracts from faecal samples demonstrates distinct differences between paediatric Crohn's disease patients and healthy controls but no significant changes resulting from exclusive enteral nutrition treatment. Metabolites, 8 (4). 82. ISSN 2218-1989

Alqarni, Abdulmalik M. and Ferro, Valerie A. and Parkinson, John A. and Dufton, Mark J. and Watson, David G. (2018) Effect of melittin on metabolomic profile and cytokine production in PMA-differentiated THP-1 cells. Vaccines, 6 (4). 72. ISSN 2076-393X

Howe, Christopher C. F. and Alshehri, Ahmed and Muggeridge, David and Mullen, Alexander B. and Boyd, Marie and Spendiff, Owen and Moir, Hannah J. and Watson, David G. (2018) Untargeted metabolomics profiling of an 80.5 km simulated treadmill ultramarathon. Metabolites, 8 (1). 14. ISSN 2218-1989

2017

Westrop, Gareth D. and Wang, Lijie and Blackburn, Gavin J. and Zhang, Tong and Zheng, Liang and Watson, David G. and Coombs, Graham H. (2017) Metabolomic profiling and stable isotope labelling of Trichomonas vaginalis and Tritrichomonas foetus reveal major differences in amino acid metabolism including the production of 2-hydroxyisocaproic acid, cystathionine and S-methylcysteine. PLOS One, 12 (12). e0189072. ISSN 1932-6203

Alwashih, Mohammad A and Watson, David G. and Andrew, Ruth and Stimson, Roland H. and Alossaimi, Manal and Blackburn, Gavin and Walker, Brian R. (2017) Plasma metabolomic profile varies with glucocorticoid dose in patients with congenital adrenal hyperplasia. Scientific Reports, 7 (1). 17092. ISSN 2045-2322

Lowe, Amanda D. and Bawazeer, Sami and Watson, David G. and McGill, Suzanne and Burchmore, Richard J. S. and Pomeroy, P. P (Paddy) and Kennedy, Malcolm W. (2017) Rapid changes in Atlantic grey seal milk from birth to weaning - immune factors and indicators of metabolic strain. Scientific Reports, 7. pp. 1-11. 16093. ISSN 2045-2322

O'Tuathaigh, Colm M. P and Mathur, Naina and O'Callaghan, Matthew J and MacIntyre, Lynsey and Harvey, Richard and Lai, Donna and Waddington, John L and Pickard, Benjamin S and Watson, David G and Moran, Paula M (2017) Specialised information processing deficits and distinct metabolomic profiles following TM-domain disruption of Nrg1. Schizophrenia Bulletin, 43 (5). 1100–1113. ISSN 0586-7614

Alwashih, Mohammad A. and Stimson, Roland H. and Andrew, Ruth and Walker, Brian R. and Watson, David G. (2017) Acute interaction between hydrocortisone and insulin alters the plasma metabolome in humans. Scientific Reports, 7 (1). 11488. ISSN 2045-2322

Siheri, Weam and Alenezi, Sameah and Tusiimire, Jonans and Watson, David G.; Alvarez-Suarez, José M, ed. (2017) The chemical and biological properties of propolis. In: Bee Products - Chemical and Biological Properties. Springer International Publishing AG, Cham, pp. 137-178. ISBN 9783319596884

Bawazeer, Sami and Muhsen Ali, Ali and Alhawiti, Aliyah and Khalaf, Abedawn and Gibson, Colin and Tusiimire, Jonans and Watson, David G. (2017) A method for the analysis of sugars in biological systems using reductive amination in combination with hydrophilic interaction chromatography and high resolution mass spectrometry. Talanta, 166. pp. 75-80. ISSN 0039-9140

Omar, Ruwida and Igoli, John O. and Zhang, Tong and Gray, Alexander I. and Ebiloma, Godwin Unekwuojo and Clements, Carol J. and Fearnley, James and Edrada Ebel, RuAngelie and Paget, Tim and de Koning, Harry P. and Watson, David G. (2017) The chemical characterization of Nigerian propolis samples and their activity against Trypanosoma brucei. Scientific Reports, 7 (1). 01038. ISSN 2045-2322

Alonezi, Sanad and Tusiimire, Jonans and Wallace, Jennifer and Dufton, Mark J. and Parkinson, John A. and Young, Louise C. and Clements, Carol J. and Park, Jin-Kyu and Jeon, Jong-Woon and Ferro, Valerie A. and Watson, David G. (2017) Metabolomic profiling of the synergistic effects of melittin in combination with cisplatin on ovarian cancer cells. Metabolites, 7 (14). pp. 1-18. ISSN 2218-1989

2016

Alanazi, Ibrahim and Grant, M. Helen and Watson, David and Henderson, Catherine (2016) Comparison of the metabolism of mephedrone in cultured and in freshly isolated primary rat hepatocytes. Applied in Vitro Toxicology, 2 (4). p. 241. ISSN 2332-1539

Khreit, Osama IG and Grant, Helen M and Henderson, Catherine and Watson, David G and Sutcliffe, Oliver B (2016) Identification of novel metabolic pathways of sitagliptin (STG) by LC/MS and LC/MS2 after incubations with rat hepatcoytes. Drug Metabolism and Disposition, 7 (4). 1000220. ISSN 1521-009X

Woods, N. and Niwasabutra, K. and Acevedo, R. and Igoli, John and Altwaijry, N.A. and Tusiimire, J. and Gray, A.I. and Watson, D.G. and Ferro, V.A.; Schijns, Virgil E.J.C. and O'Hagan, Derek T., eds. (2016) Natural vaccine adjuvants and immunopotentiators derived from plants, fungi, marine organisms, and insects. In: Immunopotentiators in Modern Vaccines. Academic Press, London, pp. 211-230. ISBN 9780128040195

Zhang, Tong and Watson, David G. and Zhang, Rong and Hou, Rong and Loeffler, I. Kati and Kennedy, Malcolm W. (2016) Changeover from signalling to energy-provisioning lipids during transition from colostrum to mature milk in the giant panda (Ailuropoda melanoleuca). Scientific Reports, 6. pp. 1-10. 36141. ISSN 2045-2322

Alonezi, Sanad and Tusiimire, Jonans and Wallace, Jennifer and Dufton, Mark J. and Parkinson, John A. and Young, Louise C. and Clements, Carol J. and Park, Jin Kyu and Jeon, Jong Woon and Ferro, Valerie A. and Watson, David G. (2016) Metabolomic profiling of the effects of melittin on cisplatin resistant and cisplatin sensitive ovarian cancer cells using mass spectrometry and biolog microarray technology. Metabolites, 6 (4). ISSN 2218-1989

MacRitchie, Neil and Volpert, Giora and Al Washih, Mohammed and Watson, David G. and Futerman, Anthony H. and Kennedy, Simon and Pyne, Susan and Pyne, Nigel J. (2016) Effect of the sphingosine kinase 1 selective inhibitor, PF-543 on arterial and cardiac remodeling in a hypoxic model of pulmonary arterial hypertension. Cellular Signalling, 28 (8). pp. 946-955. ISSN 1873-3913

do Nascimento, Ticiano Gomes and da Silva, Priscilla Fonseca and Azevedo, Lais Farias and da Rocha, Louisianny Guerra and de Moraes Porto, Isabel Cristina Celerino and Lima e Moura, Túlio Flávio Accioly and Basílio-Júnior, Irinaldo Diniz and Grillo, Luciano Aparecido Meireles and Dornelas, Camila Braga and Fonseca, Eduardo Jorge da Silva and de Jesus Oliveira, Eduardo and Zhang, Alex Tong and Watson, David G. (2016) Polymeric nanoparticles of Brazilian red propolis extract : preparation, characterization, antioxidant and leishmanicidal activity. Nanoscale Research Letters, 11. 301. ISSN 1931-7573

Scott, Fraser and Khalaf, Abedawn and Suckling, Colin and Carter, Katharine and Grant, Mary and Henderson, Catherine and Westrop, Gareth and Watson, David (2016) An evaluation of minor groove binders as anti-lung cancer therapeutics. Bioorganic and Medicinal Chemistry Letters. ISSN 0960-894X (In Press)

Siheri, Weam and Zhang, Tong and Ebiloma, Godwin Unekwuojo and Biddau, Marco and Woods, Nicola and Hussain, Muattaz Yassein and Clements, Carol J. and Fearnley, James and Edrada Ebel, RuAngelie and Paget, Timothy and Müller, Sylke and Carter, Katharine C. and Ferro, Valerie A. and De Koning, Harry P. and Watson, David G. (2016) Chemical and antimicrobial profiling of propolis from different regions within Libya. PLOS One, 11 (5). e0155355. ISSN 1932-6203

Tusiimire, Jonans and Wallace, Jennifer and Woods, Nicola and Dufton, Mark J. and Parkinson, John A. and Abbott, Grainne and Clements, Carol J. and Young, Louise and Park, Jin Kyu and Jeon, Jong Woon and Ferro, Valerie A. and Watson, David G. (2016) Effect of bee venom and its fractions on the release of pro-inflammatory cytokines in PMA-differentiated U937 cells co-stimulated with LPS. Vaccines, 4 (2). 11. ISSN 2076-393X

Paladino, Eleonora and Watson, David G. and Passarelli, Melissa K. and Lamprou, Dimitrios A. (2016) Time of flight secondary ion mass spectrometry (ToF-SIMS) in pharmaceutical sciences. In: 2016 UKICRS Workshop & Symposium, 2016-04-21 - 2016-04-22, Cardiff School of Pharmacy and Pharmaceutical Sciences. (Unpublished)

Omar, Ruwida M K and Igoli, John and Gray, Alexander I and Ebiloma, Godwin Unekwuojo and Clements, Carol and Fearnley, James and Edrada Ebel, Ru Angeli and Zhang, Tong and De Koning, Harry P and Watson, David G (2016) Chemical characterisation of Nigerian red propolis and its biological activity against Trypanosoma Brucei. Phytochemical Analysis, 27 (2). 107–115. ISSN 0958-0344

Zhang, Rong and Zhang, Tong and Ali, Ali Muhsen and Al Washih, Mohammed and Pickard, Benjamin and Watson, David G. (2016) Metabolomic Profiling of Post-Mortem Brain Reveals Changes in Amino Acid and Glucose Metabolism in Mental Illness Compared with Controls. Computational and Structural Biotechnology Journal, 14. pp. 106-116. ISSN 2001-0370

Ali, Ali Muhsen and Burleigh, Mia and Daskalaki, Evangelia and Zhang, Tong and Easton, Chris and Watson, David G. (2016) Metabolomic profiling of submaximal exercise at a standardised relative intensity in healthy adults. Metabolites. ISSN 2218-1989

2015

Zhang, Tong and Zhang, Rong and Zhang, Liang and Zhang, Zhihe and Hou, Rong and Wang, Hairui and Loeffler, I. Kati and Watson, David G. and Kennedy, Malcolm W. (2015) Changes in the milk metabolome of the giant panda (ailuropoda melanoleuca) with time after birth - three phases in early lactation and progressive individual differences. PLOS One, 10 (12). e0143417. ISSN 1932-6203

Mcilroy, George D. and Tammireddy, Seshu R. and Maskrey, Benjamin H. and Grant, Louise and Doherty, Mary K. and Watson, David G. and Delibegović, Mirela and Whitfield, Phillip D. and Mody, Nimesh (2015) Fenretinide mediated retinoic acid receptor signalling and inhibition of ceramide biosynthesis regulates adipogenesis, lipid accumulation, mitochondrial function and nutrient stress signalling in adipocytes and adipose tissue. Biochemical Pharmacology. ISSN 0006-2952

Griffiths, Kate and Hou, Rong and Wang, Hairui and Zhang, Zhihe and Zhang, Liang and Zhang, Tong and Watson, David G. and Burchmore, Richard J. S. and Loeffler, I. Kati and Kennedy, Malcolm W. (2015) Prolonged transition time between colostrum and mature milk in a bear, the giant panda, Ailuropoda melanoleuca. Royal Society Open Science, 2 (10). p. 150395. ISSN 2054-5703

Zaid, Abdel Naser and Abualhasan, Murad N and Watson, David G and Mousa, Ayman and Ghazal, Nadia and Bustami, Rana (2015) Investigation of the bioequivalence of montelukast chewable tablets after a single oral administration using a validated LC-MS/MS method. Drug Design, Development and Therapy, 9. pp. 5315-5321. ISSN 1177-8881

Westrop, Gareth D and Williams, Roderick A M and Wang, Lijie and Zhang, Tong and Watson, David G and Silva, Ana Marta and Coombs, Graham H (2015) Metabolomic analyses of Leishmania reveal multiple species differences and large differences in amino acid metabolism. PLOS One, 10 (9). e0136891. ISSN 1932-6203

MacAskill, Mark G. and Watson, David G. and Ewart, Marie-Ann and Wadsworth, Roger and Jackson, Andrew and Aitken, Emma and MacKenzie, Graeme and Kingsmore, David and Currie, Susan and Coats, Paul (2015) Improving arteriovenous fistula patency : transdermal delivery of diclofenac reduces cannulation-dependent neointimal hyperplasia via AMPK activation. Vascular pharmacology, 71. pp. 108-115. ISSN 1879-3649

Gill, A. M. and Scott, N. B. and Abbas, M. and Watson, D. G. and Place, K. and McDonald, David (2015) Ropivacaine plasma levels following high-dose local infiltration analgesia for total knee arthroplasty. Anaesthesia, 70 (7). pp. 784-790. ISSN 0003-2409

Omar, Khaled M. K. and Grant, Mary and Henderson, Catherine and Watson, David (2015) LC-MS analysis of the metabolism of the dietary constituent hesperidin by rat hepatocytes. In: 13th European ISSX meeting, 2015-06-22 - 2015-06-25, TIC Building, Strathclyde University.

Alwashih, Mohammad and Watson, David and Grant, Mary and Henderson, Catherine (2015) Metabolomics as a tool to investigate mephadrone as a drug of abuse in rat hepatocytes. In: 13th European ISSX meeting, 2015-06-22 - 2015-06-25, TIC Building, Strathclyde University.

Creek, Darren J. and Mazet, Muriel and Achcar, Fiona and Anderson, Jana and Kim, Dong Hyun and Kamour, Ruwida and Morand, Pauline and Millerioux, Yoann and Biran, Marc and Kerkhoven, Eduard J. and Chokkathukalam, Achuthanunni and Weidt, Stefan K. and Burgess, Karl E. V. and Breitling, Rainer and Watson, David G. and Bringaud, Frédéric and Barrett, Michael P. (2015) Probing the metabolic network in bloodstream-form Trypanosoma brucei using untargeted metabolomics with stable isotope labelled glucose. PLOS Pathogens, 11 (3). e1004689. ISSN 1553-7366

Daskalaki, Evangelia and Blackburn, Gavin and Kalna, Gabriela and Zhang, Tong and Anthony, Nahoum and Watson, David G. (2015) A study of the effects of exercise on the urinary metabolome using normalisation to individual metabolic output. Metabolites, 5 (1). pp. 119-139. ISSN 2218-1989

Kamleh, Muhammad Anas and Snowden, Stuart G. and Grapov, Dmitry and Blackburn, Gavin J. and Watson, David G. and Xu, Ning and Ståhle, Mona and Wheelock, Craig E. (2015) LC-MS metabolomics of psoriasis patients reveals disease severity-dependent increases in circulating amino acids that are ameliorated by anti-TNFα treatment. Journal of Proteome Research, 14 (1). pp. 557-566. ISSN 1535-3907

2014

Omar, Khaled and Grant, M. Helen and Henderson, Catherine and Watson, David George (2014) The complex degradation and metabolism of quercetin in rat hepatocyte incubations. Xenobiotica, 44 (12). pp. 1074-1082. ISSN 0049-8254

Siheri, Weam and Igoli, John O. and Gray, Alexander I. and Nasciemento, Ticiano G. and Zhang, Tong and Fearnley, James and Clements, Carol J. and Carter, Katharine C. and Carruthers, John and Edrada-Ebel, RuAngelie and Watson, David G. (2014) The isolation of antiprotozoal compounds from Libyan propolis. Phytotherapy Research, 28 (12). 1756–1760. ISSN 0951-418X

Kardar, M. N. and Zhang, T. and Coxon, G. D. and Watson, D. G. and Fearnley, J. and Seidel, V. (2014) Characterisation of triterpenes and new phenolic lipids in Cameroonian propolis. Phytochemistry, 106. pp. 156-163. ISSN 0031-9422

Zhang, Rong and Watson, David G. and Wang, Lijie and Westrop, Gareth D. and Coombs, Graham H. and Zhang, Tong (2014) Evaluation of mobile phase characteristics on three zwitterionic columns in hydrophilic interaction liquid chromatography mode for liquid chromatography-high resolution mass spectrometry based untargeted metabolite profiling of Leishmania parasites. Journal of Chromatography A, 1362. 168–179. ISSN 0021-9673

Omar, Khaled and Grant, M. Helen and Henderson, Catherine and Watson, David G (2014) The abundant dietary constituent ferulic acid forms a wide range of metabolites including a glutathione adduct when incubated with rat hepatocytes. Xenobiotica, 44 (5). pp. 432-437.

Zhang, Tong and Omar, Ruwida and Siheri, Weam and Al Mutairi, Sultan and Clements, Carol and Fearnley, James and Edrada-Ebel, Ruangelie and Watson, David (2014) Chromatographic analysis with different detectors in the chemical characterisation and dereplication of African propolis. Talanta, 120. pp. 181-190. ISSN 0039-9140

Storm, Janet and Sethia, Sonal and Blackburn, Gavin and Chokkathukalam, A and Watson, David and Breitling, R. and Coombs, Graham and Muller, S. (2014) Phosphoenolpyruvate carboxylase identified as a key enzyme in erythrocytic Plasmodium falciparum carbon metabolism. PLOS Pathogens, 10 (1). pp. 1-14. e1003876. ISSN 1553-7366

Daskalaki, Evangelia and Easton, Chris and Watson, David G. (2014) The application of metabolomic profiling to the effects of physical activity. Current Metabolomics, 2 (4). pp. 233-263. ISSN 2213-2368

2013

Abbas, M. and Ahmad, L. and Shah, Y. and Gill, M. and Watson, D.G. (2013) Development of a method to measure free and bound ropivacaine in human plasma using equilibrium dialysis and Hydrophilic interaction chromatography coupled to high resolution mass spectrometry. Talanta, 117. pp. 60-63. ISSN 0039-9140

Chintapalli, Venkateswara R and Al Bratty, Mohammed and Korzekwa, Dominika and Watson, David G and Dow, Julian A T (2013) Mapping an atlas of tissue-specific Drosophila melanogaster metabolomes by high resolution mass spectrometry. PLOS One, 8 (10). e78066.

Zhang, Tong and Watson, David G and Wang, Lijie and Abbas, Muhammad and Murdoch, Laura and Bashford, Lisa and Ahmad, Imran and Lam, Nga-Yee and Ng, Anthony C F and Leung, Hing Y (2013) Application of holistic liquid chromatography-high resolution mass spectrometry based urinary metabolomics for prostate cancer detection and biomarker discovery. PLoS ONE, 8 (6). e65880.

Abualhasan, M.N. and Batrawi, N. and Zaid, A.N. and Watson, D.G. (2013) A validated and stability indicating HPLC method for analysis of diminazene aceturate and antipyrine combination in a ready injectable solution. Drug Research, 63 (6). pp. 300-304. ISSN 2194-9379

Watson, David G and Tonelli, Francesca and Al Osaimi, Manal and Williamson, Leon and Chan, Edmond and Gorshkova, Irina and Berdyshev, Evgeny and Bittman, Robert and Pyne, Nigel J and Pyne, Susan (2013) The roles of sphingosine kinases 1 and 2 in regulating the Warburg effect in prostate cancer cells. Cellular Signalling, 25 (4). pp. 1011-1017. ISSN 1873-3913

Tonelli, F. and Alossaimi, M. and Williamson, L. and Tate, R.J. and Watson, D.G. and Chan, E. and Bittman, R. and Pyne, N.J. and Pyne, S. (2013) The sphingosine kinase inhibitor 2-(p-hyroxyanilino)-4-(p-chlorophenyl)thiazole reduces androgen receptor expression via an oxidative stress-dependent mechanism. British Journal of Pharmacology, 168 (6). pp. 1497-1505. ISSN 1476-5381

Watson, David G (2013) A rough guide to metabolite identification using high resolution liquid chromatography mass spectrometry in metabolomic profiling in metazoans. Computational and Structural Biotechnology Journal, 4 (5). e201301005. ISSN 2001-0370

Khreit, Osama Idris Gibreel and Grant, Mary and Zhang, Tong and Henderson, Catherine and Watson, David and Sutcliffe, Oliver Brook (2013) Elucidation of the phase I and phase II metabolic pathways of (+/-)-4'-nethylmethcathinone (4-MMC) and (+/-)-4'-(trifluoromethyl)methcathinone (4-TFMMC) in rat liver hepatocytes using LC-MS and LC-MS2. Journal of Pharmaceutical and Biomedical Analysis, 72. pp. 177-185. ISSN 0731-7085

Alzweiri, Muhammed and Watson, David G. and Parkinson, John A. (2013) Metabonomics as a clinical tool of analysis : LC-MS approaches. Journal of Liquid Chromatography and Related Technologies, 36 (1). pp. 94-115.

Zheng, Liang and Mackenzie, Elaine D and Karim, Saadia A and Hedley, Ann and Blyth, Karen and Kalna, Gabriela and Watson, David G and Szlosarek, Peter and Frezza, Christian and Gottlieb, Eyal (2013) Reversed argininosuccinate lyase activity in fumarate hydratase-deficient cancer cells. Cancer and Metabolism, 1 (1). 12. ISSN 2049-3002

Tonelli, Francesca and Alossaimi, Manal and Natarajan, Viswanathan and Gorshkova, Irina and Berdyshev, Evgeny and Bittman, Robert and Watson, David G and Pyne, Susan and Pyne, Nigel J (2013) The roles of sphingosine kinase 1 and 2 in regulating the metabolome and survival of prostate cancer cells. Biomolecules, 3 (2). pp. 316-333. ISSN 2218-273X

2012

Bawazeer, Saud and Sutcliffe, Oliver B and Euerby, Melvin R and Bawazeer, Sami and Watson, David G (2012) A comparison of the chromatographic properties of silica gel and silicon hydride modified silica gels. Journal of Chromatography A, 1263. pp. 61-67.

Knottenbelt, C. M. and Bawazeer, S. and Hammond, J. and Mellor, D. and Watson, D. G. (2012) Nicotine hair concentrations in dogs exposed to environmental tobacco smoke : a pilot study. Journal of Small Animal Practice, 53 (11). pp. 623-626. ISSN 0022-4510

Peretz, Hava and Watson, David G. and Blackburn, Gavin and Zhang, Tong and Lagziel, Ayala and Shtauber-Naamati, Meirav and Morad, Tova and Keren-Tardai, Elena and Greenshpun, Victoria and Usher, Sali and Shalev, Hanna and Landau, Daniel and Levartovsky, David (2012) Urine metabolomics reveals novel physiologic functions of human aldehyde oxidase and provides biomarkers for typing xanthinuria. Metabolomics, 8 (5). pp. 951-959. ISSN 1573-3882

Watson, David (2012) Pharmaceutical Analysis. Churchill Livingstone. ISBN 9780702046216

Calder, Alyson and Bell, Graham T. and Andersson, Martin and Thomson, Alison H. and Watson, David G. and Morton, Neil S. (2012) Pharmacokinetic profiles of epidural bupivacaine and ropivacaine following single-shot and continuous epidural use in young infants. Pediatric Anesthesia, 22 (5). pp. 430-437. ISSN 1155-5645

Chintapalli, Venkateswara R and Terhzaz, Selim and Wang, Jing and Al Bratty, Mohammed and Watson, David G and Herzyk, Pawel and Davies, Shireen A and Dow, Julian A T (2012) Functional correlates of positional and gender-specific renal asymmetry in Drosophila. PLOS One, 7 (4). e32577.

Zhang, Tong and Creek, Darren J. and Barrett, Michael P. and Blackburn, Gavin and Watson, David G. (2012) Evaluation of coupling reversed phase, aqueous normal phase, and hydrophilic interaction liquid chromatography with orbitrap mass spectrometry for metabolomic studies of human urine. Analytical Chemistry, 84 (4). pp. 1994-2001. ISSN 0003-2700

Scullion, Paul and Edwards, Darren and McKinnon, Heather and Miller, Stewart and Watson, David and MacIntyre, Lynsey (2012) Analysis of changes in triacylglycerol ratios in mouse liver and plasma in response to a liver X receptor agonist. Metabolomics, 8 (1). pp. 74-85. ISSN 1573-3882

Al-Tannak, N. F. and Cable, C. G. and McArthur, D. A. and Watson, D. G. (2012) A stability indicating assay for a combination of morphine sulphate with levomepromazine hydrochloride used in palliative care. Journal of Clinical Pharmacy and Therapeutics, 37 (1). pp. 71-73. ISSN 0269-4727

Bawazeer, Saud and Watson, David G. and Knottenbelt, Clare (2012) Determination of nicotine exposure in dogs subjected to passive smoking using methanol extraction of hair followed by hydrophilic interaction chromatography in combination with Fourier transform mass spectrometry. Talanta, 88. pp. 408-411. ISSN 0039-9140

Bratty, Mohammed Al and Chintapalli, Venkateswara R and Dow, Julian A T and Zhang, Tong and Watson, David G (2012) Metabolomic profiling reveals that Drosophila melanogaster larvae with the y mutation have altered lysine metabolism. FEBS Open Bio, 2. pp. 217-221.

2011

Al Bratty, Mohammed and Hobani, Yahya and Dow, Julian A. T. and Watson, David G. and Watson, David (2011) Metabolomic profiling of the effects of allopurinol on Drosophila melanogaster. Metabolomics, 7 (4). pp. 542-548.

Payne, Christopher J and Thomson, Alison H and Stearns, Adam T and Watson, David G and Zhang, Tong and Kingsmore, David B and Byrne, Dominique S and Binning, Alexander S (2011) Pharmacokinetics and tissue penetration of vancomycin continuous infusion as prophylaxis for vascular surgery. Journal of Antimicrobial Chemotherapy, 66 (11). pp. 2624-2627.

Frezza, Christian and Zheng, Liang and Folger, Ori and Rajagopalan, Kartik N and MacKenzie, Elaine D and Jerby, Livnat and Micaroni, Massimo and Chaneton, Barbara and Adam, Julie and Hedley, Ann and Kalna, Gabriela and Tomlinson, Ian P M and Pollard, Patrick J and Watson, Dave G and Deberardinis, Ralph J and Shlomi, Tomer and Ruppin, Eytan and Gottlieb, Eyal (2011) Haem oxygenase is synthetically lethal with the tumour suppressor fumarate hydratase. Nature, 477 (7363). 225–228.

Frezza, Christian and Zheng, Liang and Tennant, Daniel A. and Papkovsky, Dmitri B and Hedley, Barbara A and Kalna, Gabriela and Watson, David and Gottlieb, Eyal (2011) Metabolic profiling of hypoxic cells revealed a catabolic signature required for cell survival. PLoS One, 6 (9). e24411.

Xiao, Xiaolin and Dawson, Neil and MacIntyre, Lynsey and Morris, Brian J. and Pratt, Judith A. and Watson, David G. and Higham, Desmond J (2011) Exploring metabolic pathway disruption in the subchronic phencyclidine model of schizophrenia with the generalized singular value decomposition. BMC Systems Biology, 5. 72. ISSN 1752-0509

Khan, Abad and Khan, Muhammad I. and Iqbal, Zafar and Shah, Yasar and Ahmad, Lateef and Nazir, Shabnam and Watson, David G. and Khan, Jamshaid Ali and Nasir, Fazli and Khan, Abbas and Ismail, A.F. (2011) A new HPLC method for the simultaneous determination of ascorbic acid and aminothiols in human plasma and erythrocytes using electrochemical detection. Talanta, 84 (3). pp. 789-801. ISSN 0039-9140

t'Kindt, Ruben and Jankevics, Andris and Scheltema, Richard A. and Zheng, Liang and Watson, David G. and Dujardin, Jean-Claude and Breitling, Rainer and Coombs, Graham H. and Decuypere, Saskia (2011) Towards an unbiased metabolic profiling of protozoan parasites: optimisation of a Leishmania sampling protocol for HILIC-orbitrap analysis (vol 398, pg 2059, 2010). Analytical and Bioanalytical Chemistry, 400 (2). p. 635. ISSN 1618-2642

Sha, L. and Macintyre, L. and Machell, J.A. and Kelly, M.P. and Porteous, D.J. and Brandon, N.J. and Muir, W.J. and Blackwood, D.H. and Watson, D.G. and Clapcote, S.J. and Pickard, B.S. (2011) Transcriptional regulation of neurodevelopmental and metabolic pathways by NPAS3. Molecular Psychiatry, 17 (3). pp. 267-279.

Mullen, Alexander and Watson, David; Watson, David G., ed. (2011) Antifungal chemotherapy. In: Pharmaceutical chemistry. Churchill Livingstone, pp. 495-510. ISBN 9780443072321

Iqbal, Zafar and Elliott, Moira and Watson, David and Holyoake, Tessa and Jørgensen, Heather (2011) Analysis of imatinib in bone marrow and plasma samples of chronic myeloid leukaemia patients using solid phase extraction LC-ESI-MS. Pakistan journal of pharmaceutical sciences, 24 (3). pp. 285-291. ISSN 1011-601X

MacIntyre, L. and Zheng, L. A. and Scullion, P. and Keating, P. and Watson, D. G. (2011) Metabolomic profiling of biomarkers of liver X receptor-induced toxicity in mouse liver tissue. Metabolomics, 7 (1). pp. 54-70. ISSN 1573-3882

Alzweiri, Muhammed and Parkinson, John and Watson, David and Steer, Steven (2011) Microscopic trends in methanol/water and acetonitrile/water systems. Jordan Journal of Pharmaceutical Sciences, 4 (1). pp. 20-28.

Al-Tannak, Naser F and Bawazeer, Saud and Siddiqui, Tahir H and Watson, David G (2011) The hydrophilic interaction like properties of some reversed phase high performance liquid chromatography columns in the analysis of basic compounds. Journal of Chromatography A, 1218 (11). pp. 1486-91.

2010

Vincent, Isabel M and Creek, Darren and Watson, David G and Kamleh, Mohammed A and Woods, Debra J and Wong, Pui Ee and Burchmore, Richard J S and Barrett, Michael P (2010) A molecular mechanism for eflornithine resistance in African trypanosomes. PLOS Pathogens, 6 (11). e1001204.

t'Kindt, Ruben and Scheltema, Richard A and Jankevics, Andris and Brunker, Kirstyn and Rijal, Suman and Dujardin, Jean-Claude and Breitling, Rainer and Watson, David G and Coombs, Graham H and Decuypere, Saskia (2010) Metabolomics to unveil and understand phenotypic diversity between pathogen populations. PLOS Neglected Tropical Diseases, 4 (11). e904. ISSN 1935-2727

Khan, Abad and Khan, Muhammad I. and Iqbal, Zafar and Ahmad, Lateef and Shah, Yasar and Watson, David G. (2010) Determination of lipoic acid in human plasma by HPLC-ECD using liquid-liquid and solid-phase extraction: method development, validation and optimization of experimental parameters. Journal of Chromatography B, 878 (28). pp. 2782-2788. ISSN 1570-0232

Raghukumar, Raghavendra and Vali, Leila and Watson, Dave and Fearnley, James and Seidel, Véronique (2010) Anti-methicillin resistant Staphylococcus aureus (MRSA) activity of 'Pacific propolis' and isolated prenylflavanones. Phytotherapy Research, 24 (8). pp. 1181-1187. ISSN 0951-418X

Watson, D G (2010) The potential of mass spectrometry for the global profiling of parasite metabolomes. Parasitology, 137 (9). pp. 1409-1423.

Zheng, Liang and T'Kind, Ruben and Decuypere, Saskia and von Freyend, Simona John and Coombs, Graham H. and Watson, David G. (2010) Profiling of lipids in Leishmania donovani using hydrophilic interaction chromatography in combination with Fourier transform mass spectrometry. Rapid Communications in Mass Spectrometry, 24 (14). pp. 2074-2082. ISSN 0951-4198

Jourdan, Fabien and Cottret, Ludovic and Huc, Laurence and Wildridge, David and Scheltema, Richard and Hillenweck, Anne and Barrett, Michael P and Zalko, Daniel and Watson, David G and Debrauwer, Laurent (2010) Use of reconstituted metabolic networks to assist in metabolomic data visualization and mining. Metabolomics, 6 (2). pp. 312-321.

Goodwin, R J and Macintyre, L and Watson, D G and Scullion, S P and Pitt, A R (2010) A solvent-free matrix application method for matrix-assisted laser desorption/ionization imaging of small molecules. Rapid Communications in Mass Spectrometry, 24 (11). pp. 1682-1686.

Goodwin, R J A and Scullion, P and Macintyre, L and Watson, D G and Pitt, A R (2010) Use of a solvent-free dry matrix coating for quantitative matrix-assisted laser desorption ionization imaging of 4-bromophenyl-1,4-diazabicyclo(3.2.2)nonane-4-carboxylate in rat brain and quantitative analysis of the drug from laser microdissected tissue regions. Analytical Chemistry, 82 (9). pp. 3868-3873.

Sills, G. and Alzweiri, M. and Leach, J. and Brodie, M. and Robertson, C. and Watson, D.G. and Parkinson, J.A. (2010) Response to drug treatment in newly diagnosed epilepsy: a pilot study of 1H NMR- and MS-based metabonomic analysis. Epilepsy Research, 88 (2-3). pp. 189-195. ISSN 0920-1211

2009

Scheltema, R. A. and Decuypere, S. and Dujardin, J. C. and Watson, D. G. and Jansen, R. C. and Breitling, R. (2009) Simple data-reduction method for high-resolution LC-MS data in metabolomics. Bioanalysis, 1 (9). pp. 1551-1557. ISSN 1757-6180

Markopoulou, Catherine and Tweedle, Tracey and Watson, D.G. and Skellern, G.G. and Reda, Houssam and Petersson, Patrik and Bradstock, Hannah and Euerby, Melvin R. (2009) A study of the relative importance of lipophilic, π-π and dipole-dipole interactions on cyanopropyl, phenyl and alkyl LC phases bonded onto the same base silica. Chromatographia, 70 (5-6). pp. 705-715. ISSN 0009-5893

Hobani, Y.H. and Kamleh, A. and Watson, D.G. and Dow, J.A.T. (2009) Taking a rosy look at the drosophila metabolome by mass spectrometry. Comparative Biochemistry and Physiology - Part A: Molecular and Integrative Physiology, 153A (2). S83-S83. ISSN 1095-6433

Zheng, L. and Watson, D.G. and Johnston, B.F. and Clark, Rachael L. and Edrada-Ebel, Ruangelie and Elseheri, W. (2009) A chemometric study of chromatograms of tea extracts by correlation optimization warping in conjunction with PCA, support vector machines and random forest data modeling. Analytica Chimica Acta, 624 (1-2). pp. 257-265. ISSN 0003-2670

Awan, M.A. and Agarwal, P.K. and Watson, D.G. and McGhee, Charles N.J. and Dutton, G.N. (2009) Penetration of topical and subconjunctival corticosteroids into human aqueous humour and its therapeutic significance. British Journal of Ophthalmology, 93 (6). pp. 708-713. ISSN 0007-1161

Pournamdari, M. and Saadi, Ahmed and Ellis, E. and Andrew, Ruth and Walker, Brian and Watson, D.G. (2009) Development of a derivatisation method for the analysis of aldehyde modified amino acid residues in proteins by Fourier transform mass spectrometry. Analytica Chimica Acta, 633 (2). pp. 216-222. ISSN 0003-2670

Shah, K. and Watson, D.G. and Campbell, C. and Meek, R.M.D. (2009) Intra-articular injection composed of steroid, iohexol and local anaesthetic - is it stable? British Journal of Radiology, 82 (974). pp. 109-111. ISSN 0007-1285

Kamleh, M.A. and Dow, J.A.T. and Watson, D.G. (2009) Applications of mass spectrometry in metabolomic studies of animal model and invertebrate systems. Briefings in Functional Genomics and Proteomics, 8 (1). pp. 28-48. ISSN 1473-9550

2008

Scheltema, R.A. and Kamleh, M.A. and Wildridge, D. and Ebikeme, Charles and Watson, D.G. and Barrett, Michael P. and Jansen, Ritsert C. and Breitling, R. (2008) Increasing the mass accuracy of high-resolution LC-MS data using background ions - a case study on the LTQ-Orbitrap. Proteomics, 8 (22). pp. 4647-4656. ISSN 1615-9853

Zheng, L. and Watson, D.G. and Tettey, J.N.A. and Clements, C.A. (2008) The determination of iron as its EDTA complex in Helix aspera by hydrophilic interaction liquid chromatography coupled to Fourier transform electrospray ionisation mass spectrometry. Talanta, 76 (5). pp. 1165-1169. ISSN 0039-9140

Kamleh, M.A. and Watson, D.G. and Hobani, Y. and Dow, J.A.T. (2008) Metabolomic profiling of Drosophila using liquid chromatography Fourier transform mass spectrometry. FEBS Letters, 582 (19). pp. 2916-2922. ISSN 0014-5793

Alzweiri, Muhammed and Watson, David G. and Robertson, Chris and Sills, Graeme J. and Parkinson, John A. (2008) Comparison of different water-miscible solvents for the preparation of plasma and urine samples in metabolic profiling studies. Talanta, 74 (4). pp. 1060-1065. ISSN 0039-9140

Labyad, N.S. and Watson, D.G. and Pournamdari, M. and Cable, C.G. and Stanley, E. (2008) Evaluation of the stability of morphine sulphate in combination with Instillagel. Journal of Clinical Pharmacy and Therapeutics, 33 (3). pp. 263-271. ISSN 0269-4727

Wei, L.Q. and Watson, D.G. and Fearnley, J. (2008) Analysis of sugars in bee pollen and propolis by ligand exchange chromatography in combination with pulsed amperometric detection and mass spectrometry. Journal of Food Composition and Analysis, 21 (1). pp. 78-83. ISSN 0889-1575

Mohanty, S. and Hollinshead, J. and Jones, L. and Jones, P.W. and Thomas, D. and Watson, A.A. and Watson, D.G. and Gray, A.I. (2008) Annona muricata (graviola): toxic or therapeutic. Natural Product Communications, 3 (1). pp. 31-33.

Seidel, Veronique and Peyfoon, Elham and Watson, David G. and Fearnley, James (2008) Comparative study of the antibacterial activity of propolis from different geographical and climatic zones. Phytotherapy Research, 22 (9). pp. 1256-1263. ISSN 0951-418X

Zhang, T. and Watson, D.G. and Lu, D. and Carr, D. and Trager, L. (2008) Determination of cross-linking residues in a pharmaceutical polymer by liquid chromatography-high resolution full scan mass spectrometry. Talanta, 76 (3). pp. 509-512. ISSN 0039-9140

Kamleh, M.A. and Barrett, M.P. and Wildridge, D. and Burchmore, R.J.S. and Scheltema, R.A. and Watson, D.G. (2008) Metabolomic profiling using Orbitrap Fourier transform mass spectrometry with hydrophilic interaction chromatography : a method with wide applicability to analysis of biomolecules. Rapid Communications in Mass Spectrometry, 22 (12). pp. 1912-1918. ISSN 0951-4198

Zhang, Tong and Khadra, Ibrahim and Euerby, Melvin R. and Skellern, G.G. and Watson, David G. and Tettey, J.N.A. (2008) Simultaneous analysis of basic, acidic and neutral compounds on an endcapped octadecylsilane silica-based monolith by pressure-assisted capillary electrochromatography. Electrophoresis, 29 (4). pp. 944-951. ISSN 0173-0835

2007

Lyon, R.C. and Johnston, S.M. and Watson, D.G. and McGarvie, G. and Ellis, E.M. (2007) Synthesis and catabolism of gamma-hydroxybutyrate in SH-SY5Y human neuroblastoma cells. Journal of Biological Chemistry, 282 (36). pp. 25986-25992. ISSN 1083-351X

MacKenzie, E.D. and Selak, M.A. and Tennant, D.A. and Payne, L.J. and Crosby, S. and Frederiksen, C.M. and Watson, D.G. and Gottlieb, E. (2007) Cell-permeating alpha-ketoglutarate derivatives alleviate pseudohypoxia in succinate dehydrogenase-deficient cells. Molecular and Cellular Biology, 27 (9). pp. 3282-3289. ISSN 0270-7306

Zhang, T. and Watson, D.G. and Tettey, J.N.A. and Stearns, A.T. and Binning, A.R. and Payne, C.J. (2007) Determination of vancomycin in serum by liquid chromatography-high resolution full scan mass spectrometry. Journal of Chromatography B, 857 (2). pp. 352-356. ISSN 1570-0232

Ghimire, M. and McInnes, F.J. and Watson, D.G. and Mullen, A. and Stevens, H. (2007) In-vitro / in-vivo correlation of pulsatile drug release from press coated tablet formulations: a pharmacoscintigraphic study in the beagle dog. European Journal of Pharmaceutics and Biopharmaceutics, 67 (2). pp. 515-523. ISSN 0939-6411

Watson, D.G. and Husain, S. and Brennan, S. and Baird, J. and Finlayson, D. (2007) The chemical stability of admixtures of injectable corticosteroid and local anaesthetics. CME Orthopaedics, 4 (3). pp. 81-83. ISSN 1367-8957

2006

Boibessot, I. and Tettey, J.N.A. and Skellern, G.G. and Watson, D.G. and Grant, M.H. (2006) The metabolism of isometamidium in hepatocytes from control and inducer treated rats. Journal of Veterinary Pharmacology and Therapeutics, 29 (6). pp. 547-553. ISSN 0140-7783

Watson, D. G. and Peyfoon, E. and Zheng, L. and Lu, D. and Seidel, V. and Johnston, B. and Parkinson, J. A. and Fearnley, J. (2006) Application of principal components analysis to 1H-NMR data obtained from propolis samples of different geographical origin. Phytochemical Analysis, 17 (5). pp. 323-331. ISSN 0958-0344

Vu Dang, Hoang and Gray, Alexander I. and Watson, David and Bates, Catharine D. and Scholes, Peter and Eccleston, Gillain M. (2006) Composition analysis of two batches of polysorbate 60 using MS and NMR techniques. Journal of Pharmaceutical and Biomedical Analysis, 40 (5). pp. 1155-1165. ISSN 0731-7085

Stumpe, M. and Miller, C. and Morton, N.S. and Bell, G. and Watson, D.G. (2006) High-performance liquid chromatography determination of σ1-acid glycoprotein in small volumes of plasma from neonates. Journal of Chromatography B, 831 (1-2). pp. 81-84. ISSN 1570-0232

Short, D.M. and Lyon, R.C. and Watson, D.G. and Barski, O.A. and McGarvie, G. and Ellis, E. (2006) Metabolism of trans, trans-muconaldehyde, a cytotoxic metabolite of benzene, in mouse liver by alcohol dehydrogenase Adh1 and aldehyde reductase AKR1A4. Toxicology and Applied Pharmacology, 210 (1-2). pp. 163-170. ISSN 0041-008X

2005

Adu, J.K. and Lau, S. and Watson, D.G. and Euerby, M.R. and Skellern, G.G. and Tettey, J.N.A. (2005) Capillary electrochromatography of therapeutic peptides on mixed-mode butylmethacrylate monoliths. Electrophoresis, 26 (18). pp. 3445-3451. ISSN 0173-0835

McInnes, F.J. and Thapa, P. and Baillie, A.J. and Welling, P. and Watson, D.G. and Gibson, I. and Nolan, A. and Stevens, H. (2005) In vivo evaluation of nicotine lyophilised nasal insert in sheep. International Journal of Pharmaceutics, 304 (1-2). pp. 72-82. ISSN 0378-5173

Selak, M.A. and Armour, S.M. and MacKenzie, E.D. and Boulahbel, H. and Watson, D.G. and Mansfield, K.D. and Pan, Y. and Simon, M.C. and Thompson, C.B. and Gottlieb, E. (2005) Succinate links TCA cycle dysfunction to oncogenesis by inhibiting HIF- prolylhydroxylase. Cancer Cell, 7. pp. 77-85. ISSN 1878-3686

2004

Watson, D.G. (2004) Highly hydrophilic fused aggregates (microsponges) from a C12 spermine bolaamphiphile. Journal of Physical Chemistry B, 108 (24). pp. 8129-8135. ISSN 1520-6106

Atsriku, C. and Grant, M.H. and Skellern, G.G. and Watson, D.G. (2004) The effects of inducing agents on the metabolism of pentamidine by isolated rat hepatocytes. Toxicology, 194 (3). pp. 234-235. ISSN 0300-483X

2003

Atsriku, C. and Skellern, G.G. and Grant, M.H. and Watson, D.G. (2003) The effect of inducing agents on the metabolism of trypanocidal diamidines by isolated rat hepatocytes. Chemico-Biological Interactions, 146 (3). pp. 297-305. ISSN 0009-2797

Jairaj, Mark and Watson, D.G. and Grant, M. Helen and Skellern, G.G. (2003) The toxicity of opiates and their metabolites in HepG2 cells. Chemico-Biological Interactions, 146 (2). pp. 121-129. ISSN 0009-2797

2002

Garofalo, A. and Rowlinson, M. and Amambua, N. and Hughes, J.M. and Kelly, S.M. and Price, N. and Cooper, A. and Watson, D.G. and Kennedy, M.W. and Bradley, J.E. (2002) The FAR protein family of the nematode caenorhabditis elegans: differential lipid binding properties, structural characteristics, and developmental regulation. Journal of Biological Chemistry, 278 (10). pp. 8065-8074. ISSN 1083-351X

Jairaj, M. and Watson, D.G. and Grant, M.H. and Skellern, G.G. (2002) Metabolic profiling of the antitussive drug pholcodine in rat hepatocytes. In: Gordon Research Conference on Drug Metabolism, 2002-07-14 - 2002-07-19.

Atsriku, C. and Watson, D.G. and Grant, M.H. and Skellern, G.G. (2002) The application of liquid chromatography-tandem mass spectrometry to in vitro metabolic studies of pentamidine by induced isolated rat hepatocytes. In: 50th Meeting of the American Society for Mass Spectrometry, 2002-06-02 - 2002-06-06.

Jairaj, M. and Watson, D.G. and Grant, M.H. and Skellern, G.G. (2002) Comparative biotransformation of morphine, codeine and pholcodine in rat hepatocytes: identification of a novel metabolite of pholcodine. Xenobiotica, 32 (12). pp. 979-986. ISSN 0049-8254

Atsriku, C. and Watson, D.G. and Tettey, J.N.A. and Grant, M.H. and Skellern, G.G. (2002) Determination of diminazene aceturate in pharmaceutical formulations by HPLC and identification of related substances by lC/MS. Journal of Pharmaceutical and Biomedical Analysis, 30 (4). pp. 979-986. ISSN 0731-7085

Boibessot, I. and Grant, M.H. and Turner, M.C.J. and Skellern, G.G. and Watson, D.G. and Goldie, E.I. and Connel, G. and Macintosh, A. (2002) Metabolism and distribution of phenanthridine trypanocides in trypanosome Brucei brucei. Acta Tropica, 84 (3). pp. 219-228. ISSN 0001-706X

Oliveira, E.D.J. and Watson, D.G. and Grant, M.H. (2002) Metabolism of quercetin and kaempferol by rat hepatocytes and identification of flavonoid glycosides in plasma. Xenobiotica, 32 (4). pp. 279-287. ISSN 0049-8254

Jairaj, M. and Watson, D.G. and Grant, M.H. and Skellern, G.G. (2002) Toxicity of codeine, codeinone and oxycodone in hep g2 cells: identification of a codeinone-glutathione conjugate by lC/+ECI-MS/MS. In: 50th Meeting of the American Society for Mass Spectrometry, 2002-06-02 - 2002-06-06.

Atsriku, C. and Watson, D.G. and Grant, M.H. and Skellern, G.G. (2002) The effects of inducing agents on the metabolism of pentamidine in isolated hepatocytes. In: Pfizer Drug Discovery 2002, 1900-01-01.

Atsriku, C. and Skellern, G.G. and Watson, D.G. and Grant, M.H. (2002) The effects of inducing agents on the metabolism of trypanocidal diamidines by isolated rat hepatocytes. In: RSC-DMG 2002: New Technologies in Drug Discovery, 2002-12-12 - 2002-12-13.

2001

Atsriku, C. and Skellern, G.G. and Watson, D.G. and Grant, M.H. (2001) High-performance liquid chromatographic determination of diminazene aceturate in the presence of its related substances. In: British Pharmaceutical Conference, 2001-09-23 - 2001-09-26.

O'Hare, R. and Muir, A. and Chapman, S. and Watson, D.G. and Hudson, S.A. (2001) Identification of the pharmaceutical care issues of rheumatoid arthritis patients in secondary care. Pharmacy World and Science, 23 (5). pp. 183-184. ISSN 0928-1231

Denk, Oliver M. and Watson, D.G. and Skellern, G.G. (2001) Chiral analysis of methylphenidate and dextromoramide by capillary electrophoresis. Journal of chromatography. B, Biomedical sciences and applications, 761 (1). pp. 61-68. ISSN 1387-2273

Watson, D.G. and Oliveira, E.D.J. and Boyter, A.C. and Dagg, K.D. (2001) A rapid and sensitive method for the determination of the amount of theophylline in blood spots. Journal of Pharmacy and Pharmacology, 53 (3). pp. 413-416. ISSN 0022-3573

Jairaj, M. and Watson, D.G. and Grant, M.H. and Skellern, G.G. (2001) Identification of metabolites of pholcodine by lC/MS. In: Proceedings of the Spring Symposium of the Chromatographic Society, 1900-01-01.

Boibessot, I. and Grant, M.H. and Skellern, G.G. and Watson, D.G. (2001) Isometamidium metabolism and distribution in rat hepatocytes. In: 26th Meeting of the International Scientific Council for Trypanosomiasis Research and Control, 2001-10-01 - 2001-10-05.

Jairaj, M. and Watson, D.G. and Grant, M.H. and Skellern, G.G. (2001) Metabolic profiling of the antitissive pholcodine in rat hepatocytes : identification of a novel metabolite by lC/+ESI- mS. In: 49th American Society for Mass Spectrometry Conference on Mass Spectrometry and Allied Topics, 2001-05-27 - 2001-05-31.

Atsriku, C. and Skellern, G.G. and Watson, D.G. and Grant, M.H. (2001) RP-HPLC determination of dimanazene aceturate in pharmaceutical preparations. In: 26th Meeting of the International Scientific Council for Trypanosomiasis Research and Control, 2001-10-01 - 2001-10-05.

Jairaj, M. and Skellern, G.G. and Watson, D.G. and Grant, M.H.; (2001) Study of the in vitro metabolism of the antitussive pholcodine: metabolic profiling and pharmacokinetics in isolated rat hepatocytes. In: British Pharmaceutical Conference: science proceedings, Glasgow, September 23rd - 26th, 2001. Pharmaceutical Press, GBR. ISBN 9780853695127

Jairaj, M. and Watson, D.G. and Skellern, G.G. and Grant, M.H. (2001) The metabolism of the antitussive pholcodine in isolated rat hepatocytes: identification of a novel metabolite and toxicological implications. Toxicology, 168 (1). pp. 135-136. ISSN 0300-483X

2000

Dufès, Christine and Schätzlein, A.G. and Tetley, L. and Gray, A.I. and Watson, D.G. and Olivier, J.C. and Couet, W. and Uchegbu, I.F. (2000) Niosomes and polymeric chitosan based vesicles bearing transferrin and glucose ligands for drug targeting. Pharmaceutical Research, 17 (10). pp. 1250-1258. ISSN 0724-8741

1996

Tahraoui, A. and Watson, D.G. and Skellern, G.G. and Hudson, S.A. and Petrie, P. and Faccenda, K. (1996) Comparative study of the determination of bupivacaine in human plasma by gas chromatography mass spectrometry and high-performance liquid chromatography. Journal of Pharmaceutical and Biomedical Analysis, 15 (2). pp. 251-257. ISSN 0731-7085

Carter, S.M.B. and Watson, D.G. and Midgley, J.M. and Logan, R.W. (1996) Synthesis and characterisation of acyl glycines. Their measurement in single blood spots by gas chromatography-mass spectrometry to diagnose inborn errors of metabolism. Journal of Chromatography B: Biomedical Applications, 677 (1). pp. 29-35. ISSN 1572-6495

1991

Carter, S.M.B. and Midgely, J.M. and Watson, D.G. and Logan, R.W. (1991) Measurement of urinary medium chain acyl glycines by gas-chromatography negative-ion chemical ionization mass-spectrometry. Journal of Pharmaceutical and Biomedical Analysis, 9 (10-12). pp. 969-975. ISSN 0731-7085

This list was generated on Tue Mar 19 06:50:50 2024 GMT.