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2024

Ali-Jerman, Hawraa and Al-Quraishi, Zainab and Muglikar, Ashish and Perrie, Yvonne and Tate, Rothwelle J. and Mullin, Margaret and McNeill, Gayle and MacKenzie, Graeme and Dufès, Christine (2024) Enhancing transfection efficacy in glioma cells : a comparison of microfluidic versus manual polypropylenimine dendriplex formation. International Journal of Nanomedicine. ISSN 1176-9114 (In Press)

2023

Maeyouf, Khadeejah and Sakpakdeejaroen, Intouch and Somani, Sukrut and Meewan, Jitkasem and Ali-Jerman, Hawraa and Laskar, Partha and Mullin, Margaret and MacKenzie, Graeme and Tate, Rothwelle J. and Dufès, Christine (2023) Transferrin-bearing, zein-based hybrid lipid nanoparticles for drug and gene delivery to prostate cancer cells. Pharmaceutics, 15 (11). 2643. ISSN 1999-4923

2022

Meewan, Jitkasem and Somani, Sukrut and Almowalad, Jamal Mohammed J and Laskar, Partha and Mullin, Margaret and MacKenzie, Graeme and Khadke, Swapnil and Perrie, Yvonne and Dufès, Christine (2022) Preparation of zein-based nanoparticles : nanoprecipitation versus microfluidic-assisted manufacture, effects of PEGylation on nanoparticle characteristics and cellular uptake by melanoma cells. International Journal of Nanomedicine, 17. pp. 2809-2822. ISSN 1176-9114

Almowalad, Jamal and Laskar, Partha and Somani, Sukrut and Meewan, Jitkasem and Tate, Rothwelle J. and Dufès, Christine (2022) Lactoferrin- and dendrimer-bearing gold nanocages for stimulus-free DNA delivery to prostate cancer cells. International Journal of Nanomedicine, 17. pp. 1409-1421. ISSN 1176-9114

Meewan, Jitkasem and Somani, Sukrut and Laskar, Partha and Irving, Craig and Mullin, Margaret and Woods, Stuart and Roberts, Craig W. and Alzahrani, Abdullah R. and Ferro, Valerie A. and McGill, Suzanne and Weidt, Stefan and Burchmore, Richard and Dufès, Christine (2022) Limited impact of the protein corona on the cellular uptake of PEGylated zein micelles by melanoma cancer cells. Pharmaceutics, 14 (2). 439. ISSN 1999-4923

van der Walle, Christopher F. and Dufès, Christine and Desai, Arpan S. and Kerby, Julie and Broadhead, Joanne and Tam, Alice and Rattray, Zahra (2022) Report on webinar series cell and gene therapy : from concept to clinical use. Pharmaceutics, 14 (1). 168. ISSN 1999-4923

2021

Laskar, Partha and Dufès, Christine (2021) Emergence of cationic polyamine dendrimersomes : design, stimuli sensitivity and potential biomedical applications. Nanoscale Advances, 3 (21). pp. 6007-6026. ISSN 2516-0230

Almowalad, Jamal and Somani, Sukrut and Laskar, Partha and Meewan, Jitkasem and Tate, Rothwelle J. and Mullin, Margaret and Dufès, Christine (2021) Lactoferrin-bearing gold nanocages for gene delivery in prostate cancer cells in vitro. International Journal of Nanomedicine, 16. pp. 4391-4407. ISSN 1176-9114

Sakpakdeejaroen, Intouch and Somani, Sukrut and Laskar, Partha and Mullin, Margaret and Dufès, Christine (2021) Regression of melanoma following intravenous injection of plumbagin entrapped in transferrin-conjugated, lipid–polymer hybrid nanoparticles. International Journal of Nanomedicine, 16. pp. 2615-2631. ISSN 1176-9114

Laskar, Partha and Somani, Sukrut and Mullin, Margaret and Tate, Rothwelle and Warzecha, Monika and Bowering, Deborah and Keating, Patricia and Irving, Craig and Leung, Hing Y and Dufès, Christine (2021) Octadecyl chain-bearing PEGylated poly(propyleneimine)-based dendrimersomes : physicochemical studies, redox-responsiveness, DNA condensation, cytotoxicity and gene delivery to cancer cells. Biomaterials Science, 9 (4). pp. 1431-1448. ISSN 2047-4830

2020

Rushworth, Linda K. and Hewit, Kay and Munnings-Tomes, Sophie and Somani, Sukrut and James, Daniel and Shanks, Emma and Dufès, Christine and Straube, Anne and Patel, Rachana and Leung, Hing Y. (2020) Repurposing screen identifies mebendazole as a clinical candidate to synergise with docetaxel for prostate cancer treatment. British Journal of Cancer, 122 (4). pp. 517-527. ISSN 1532-1827

Sakpakdeejaroen, Intouch and Somani, Sukrut and Laskar, Partha and Irving, Craig and Mullin, Margaret and Dufes, Christine (2020) Anti-tumor activity of intravenously administered plumbagin entrapped in targeted nanoparticles. Journal of Biomedical Nanotechnology, 16 (1). pp. 85-100. ISSN 1550-7033

2019

Laskar, Partha and Somani, Sukrut and Campbell, Sara Jane and Mullin, Margaret and Keating, Patricia and Tate, Rothwelle J. and Irving, Craig and Leung, Hing Y. and Dufès, Christine (2019) Camptothecin-based dendrimersomes for gene delivery and redox-responsive drug delivery to cancer cells. Nanoscale, 11 (42). pp. 20058-20071. ISSN 2040-3372

Obeid, Mohammad A. and Dufès, Christine and Somani, Sukrut and Mullen, Alexander B. and Tate, Rothwelle J. and Ferro, Valerie A. (2019) Proof of concept studies for siRNA delivery by non-ionic surfactant vesicles : in vitro and in vivo evaluation of protein knockdown. Journal of Liposome Research, 29 (3). pp. 229-238. ISSN 0898-2104

Sakpakdeejaroen, Intouch and Somani, Sukrut and Laskar, Partha and Mullin, Margaret and Dufès, Christine (2019) Transferrin‐bearing liposomes entrapping plumbagin for targeted cancer therapy. Journal of Interdisciplinary Nanomedicine, 4 (2). pp. 54-71. ISSN 2058-3273

Sakpakdeejaroen, Intouch and Somani, Sukrut and Mullin, Margaret and Dufès, Christine (2019) Development of transferrin-bearing vesicles encapsulating aspirin for cancer therapy. Journal of Liposome Research, 30 (2). pp. 174-181. ISSN 0898-2104

2018

Laskar, Partha and Somani, Sukrut and Altwaijry, Najla Abdullah S and Mullin, Margaret and Bowering, Deborah and Warzecha, Monika and Keating, Patricia and Tate, Rothwelle J. and Leung, Hing Y. and Dufès, Christine (2018) Redox-sensitive, cholesterol-bearing PEGylated poly(propyleneimine)-based dendrimersomes for drug and gene delivery to cancer cells. Nanoscale, 10 (48). pp. 22830-22847. ISSN 2040-3372

Maniam, Geetha and Mai, Chun-Wai and Jusoh, Mohd Zulkefeli Mat and Dufès, Christine and Tan, Doryn Meam-Yee and Fu, Ju-Yen (2018) Challenges and opportunities of nanotechnology as delivery platform for tocotrienols in cancer therapy. Frontiers in Pharmacology, 9. 1358. ISSN 1663-9812

Altwaijry, Najla and Somani, Sukrut and Dufès, Christine (2018) Targeted nonviral gene therapy in prostate cancer. International Journal of Nanomedicine, 13. 5753—5767. ISSN 1176-9114

Somani, Sukrut and Laskar, Partha and Altwaijry, Najla and Kewcharoenvong, Paphitchaya and Irving, Craig and Robb, Gillian and Pickard, Benjamin S. and Dufès, Christine (2018) PEGylation of polypropylenimine dendrimers : effects on cytotoxicity, DNA condensation, gene delivery and expression in cancer cells. Scientific Reports, 8. 9410. ISSN 2045-2322

Altwaijry, Najla and Somani, Sukrut and Parkinson, John A. and Tate, Rothwelle J. and Keating, Patricia and Warzecha, Monika and MacKenzie, Graeme R. and Leung, Hing Y. and Dufès, Christine (2018) Regression of prostate tumors after intravenous administration of lactoferrin-bearing polypropylenimine dendriplexes encoding TNF-α, TRAIL and interleukin-12. Drug Delivery, 25 (1). pp. 679-689. ISSN 1521-0464

2017

Karim, Reatul and Somani, Sukrut and Al Robaian, Majed and Mullin, Margaret and Amor, Rumelo and McConnell, Gail and Dufès, Christine (2017) Tumor regression after intravenous administration of targeted vesicles entrapping the vitamin E α-tocotrienol. Journal of Controlled Release, 246. pp. 79-87. ISSN 0168-3659

2015

Somani, Sukrut and Robb, Gillian and Pickard, Benjamin S. and Dufes, Christine (2015) Enhanced gene expression in the brain following intravenous administration of lactoferrin-bearing polypropylenimine dendriplex. Journal of Controlled Release, 217. pp. 235-242. ISSN 0168-3659

Lim, Li Ying and Koh, Pei Yin and Somani, Sukrut and Al Robaian, Majed and Karim, Reatul and Yean, Yi Lyn and Mitchell, Jennifer and Tate, Rothwelle J. and Edrada-Ebel, RuAngelie and Blatchford, David R. and Mullin, Margaret and Dufès, Christine (2015) Tumor regression following intravenous administration of lactoferrin- and lactoferricin-bearing dendriplexes. Nanomedicine: Nanotechnology, Biology and Medicine, 11 (6). pp. 1445-1454. ISSN 1549-9634

Somani, Sukrut and Dufes, Christine (2015) Transferrin-bearing dendrimers for cancer therapy : an update. Nanomedicine, 10 (14). pp. 2125-2127. ISSN 1743-5889

Fu, Ju Yen and Dufès, Christine (2015) Anti-cancer efficacy of intravenously administered tumor-targeted vesicles entrapping tocotrienol. Pharmaceutical Nanotechnology, 2 (4). pp. 172-181. ISSN 2211-7385

2014

Somani, Sukrut and Dufès, Christine (2014) Applications of dendrimers for brain delivery and cancer therapy. Nanomedicine, 9 (15). pp. 2403-2414. ISSN 1743-5889

Somani, Sukrut and Blatchford, David R. and Millington, Owain and Stevenson, M. Lynn and Dufès, Christine (2014) Transferrin-bearing polypropylenimine dendrimer for targeted gene delivery to the brain. Journal of Controlled Release, 188. pp. 78-86. ISSN 0168-3659

Rosenfeldt, MT and Bell, LA and Long, JS and O'Prey, J and Nixon, C and Roberts, F and Dufès, C and Ryan, KM (2014) E2F1 drives chemotherapeutic drug resistance via ABCG2. Oncogene, 33. pp. 4164-4172. ISSN 0950-9232

Owain, Andrew and Dufès, Christine and Moscatelli, Davide and Mayes, Eric and Lovell, Jonathan and Katti, Kattesh and Sokolov, Konstantin and Mazza, Mariarosa and Fontaine, Olivier and Rannard, Steve and Stone, Vicki (2014) The application of nanotechnology in medicine : treatment and diagnostics. Nanomedicine, 9 (9). pp. 1291-1294. ISSN 1743-5889

El-Hammadi, Mazen M. and MacLellan, Steven and Dufès, Christine and Holmes, William M. and Condon, Barrie and Uchegbu, Ijeoma F. and Schatzlein, Andreas G. (2014) Size-tuneable nanometric MRI contrast agents for the imaging of molecular weight dependent transport processes. Pharmaceutical Nanotechnology, 2 (3). pp. 129-137. ISSN 2211-7385

Al Robaian, Majed Mansour Madi and Chiam, Ker Yi and Blatchford, David and Dufès, Christine (2014) Therapeutic efficacy of intravenously administered transferrin-conjugated dendriplexes on prostate carcinomas. Nanomedicine, 9 (4). pp. 421-434. ISSN 1743-5889

2013

Dufès, Christine and Al Robaian, Majed and Somani, Sukrut (2013) Transferrin and the transferrin receptor for the targeted delivery of therapeutic agents to the brain and cancer cells. Therapeutic Delivery, 4 (5). pp. 629-640. ISSN 2041-5990

Dufès, Christine (2013) Dendrimer-Based Drug Delivery Systems: From Theory to Practice Edited by Yiyun Cheng. [Review]

Lemarié, Fanny and Chang, Chun Wai and Blatchford, David and Amor, Rumelo and Norris, Greg and Tetley, Laurence and McConnell, Gail and Dufès, Christine (2013) Antitumor activity of the tea polyphenol epigallocatechin-3-gallate encapsulated in targeted vesicles after intravenous administration. Nanomedicine, 8 (2). pp. 181-192. ISSN 1743-5889

2012

Lemarié, Fanny and Croft, Daniel and Tate, Rothwelle and Ryan, Kevin M. and Dufès, Christine (2012) Tumor regression following intravenous administration of a tumor-targeted p73 gene delivery system. Biomaterials, 33. pp. 2701-2709. ISSN 1878-5905

2011

Wilkinson, Simon and Croft, Daniel R. and O'Prey, Jim and Meedendorp, Arenda and O’Prey, Margaret and Dufès, Christine and Ryan, Kevin M. (2011) The cyclin-dependent kinase PITSLRE/CDK11 is required for successful autophagy. Autophagy, 7 (11). pp. 1295-1301.

Aldawsari, Hibah Mobarak and Edrada-Ebel, Ruangelie and Blatchford, David and Tate, Rothwelle and Tetley, Laurence and Dufès, Christine (2011) Enhanced gene expression in tumors after intravenous administration of arginine-, lysine- and leucine-bearing polypropylenimine polyplex. Biomaterials, 32 (25). pp. 5889-5899. ISSN 1878-5905

Fu, J.Y. and Zhang, Wei and Blatchford, David and Tetley, Laurence and Mcconnell, Gail and Dufès, Christine (2011) Novel tocotrienol-entrapping vesicles can eradicate solid tumors after intravenous administration. Journal of Controlled Release, 154 (1). pp. 20-26. ISSN 0168-3659

Fu, Ju Yen and Zhang, Wei and Blatchford, David and Tetley, Laurence and Mcconnell, Gail and Dufès, Christine (2011) Novel tocotrienol-entrapping vesicles can eradicate solid tumors after intravenous administration. In: 38th Annual Meeting of the Controlled Release Soceity, 2011-07-30 - 2011-08-03. (Unpublished)

Dufès, Christine; Watson, David G., ed. (2011) Drug and gene delivery systems. In: Pharmaceutical Chemistry. Churchill Livingstone, pp. 581-590. ISBN 978-0-443-07232-1

Dufès, Christine; van der Walle, Christopher, ed. (2011) Brain delivery of peptides and proteins. In: Peptide and protein delivery. Elsevier, pp. 105-122. ISBN 978-0-12-384935-9

Dufès, Christine (2011) Delivery of the vitamin E compound tocotrienol to cancer cells. Therapeutic Delivery, 2 (11). pp. 1385-1389.

Aldawsari, Hibah Mobarak and Sundara Raj, Behin and Edrada-Ebel, Ruangelie and Blatchford, David and Tate, Rothwelle and Tetley, Laurence and Dufès, Christine (2011) Enhanced gene expression in tumors after intravenous administration of arginine-, lysine- and leucine-bearing polyethylenimine polyplex. Nanomedicine: Nanotechnology, Biology and Medicine, 7 (5). pp. 815-823.

2010

Koppu, Swati and Oh, Yew Jinn and Edrada-Ebel, R. and Blatchford, David R. and Tetley, L. and Tate, R. and Dufès, Christine (2010) Tumor regression after systemic administration of a novel tumor-targeted gene delivery system carrying a therapeutic plasmid DNA. Journal of Controlled Release, 143 (2). pp. 215-221. ISSN 0168-3659

Aldawsari, Hibah Mobarak and Sundara Raj, Behin and Edrada-Ebel, Ruangelie and Blatchford, David and Tate, Rothwelle and Dufès, Christine (2010) Enhanced transfection efficacy of polyethylenimine by surface modification with arginine, lysine, and leucine. Controlled Release Society Newsletter, 27 (6). pp. 12-14.

2009

Fu, Ju Yen and Blatchford, David R. and Tetley, L. and Dufès, Christine (2009) Tumor regression after systemic administration of tocotrienol entrapped in tumor-targeted vesicles. Journal of Controlled Release, 140 (2). pp. 95-99. ISSN 0168-3659

2008

Uchegbu, I.F. and Dufès, Christine M. and Kan, Pei Lee and Schätzlein, A.G.; Templeton, Nancy Smyth, ed. (2008) Polymers and dendrimers for gene delivery in gene therapy. In: Gene and cell therapy: therapeutic mechanisms and strategies 3rd ed. CRC Press, pp. 321-339. ISBN 978-0-8493-8768-5

Holmes, W.M. and Maclellan, S. and Condon, B. and Dufès, Christine and Evans, T.R.J. and Uchegbu, I.F. and Schätzlein, A.G. (2008) High-resolution 3D isotropic MR imaging of mouse flank tumours obtained in vivo with solenoid RF micro-coil. Physics in Medicine and Biology, 53. pp. 505-513. ISSN 0031-9155

2007

Bell, Helen S. and Dufès, Christine and O'Prey, Jim and Crighton, Diane and Bergamaschi, Daniele and Lu, Xin and Schätzlein, Andreas G. and Vousden, Karen H. and Ryan, Kevin (2007) A p53-derived apoptotic peptide derepresses p73 to cause tumor regression in vivo. Journal of Clinical Investigation, 117 (4). pp. 1008-1018. ISSN 0021-9738

2006

Qu, Xioazhong and Khutoryanskiy, Vitaliy V. and Stewart, Ailsa and Rahman, Samina and Papahadjopoulos-Sternberg, Brigitte and Dufès, Christine and McCarthy, Dave and Wilson, Clive G. and Lyons, Robert and Carter, Katharine C. and Schätzlein, Andreas and Uchegbu, Ijeoma F. (2006) Carbohydrate-based micelle clusters which enhance hydrophobic drug bioavailability by up to 1 order of magnitude. Biomacromolecules, 7 (12). pp. 3452-3459. ISSN 1525-7797

2005

Dufès, Christine and Uchegbu, Ijeoma F. and Schätzlein, Andreas G. (2005) Dendrimers in gene delivery. Advanced Drug Delivery Reviews, 57 (15). pp. 2177-2202. ISSN 0169-409X

Schätzlein, Andreas G. and Zinselmeyer, Bernd H. and Elouzi, Adurrahim and Dufès, Christine and Chim, Ya Tsz A. and Roberts, Clive J. and Davies, Martyn C. and Munro, Avril and Gray, Alexander I. and Uchegbu, Ijeoma F. (2005) Preferential liver gene expression with polypropylenimine dendrimers. Journal of Controlled Release, 101 (1-3). pp. 247-258. ISSN 0168-3659

Dufès, Christine and Keith, W. Nicol and Bilsland, Alan and Proutski, Irina and Uchegbu, Ijeoma F. and Schätzlein, Andreas G. (2005) Synthetic anticancer gene medicine exploits intrinsic antitumor activity of cationic vector to cure established tumors. Cancer Research, 65 (18). pp. 8079-84. ISSN 0008-5472

2004

Dufès, Christine and Muller, Jean-Marc and Couet, William and Olivier, Jean-Christophe and Uchegbu, I.F. and Schätzlein, Andreas G. (2004) Anticancer drug delivery with transferrin targeted polymeric chitosan vesicles. Pharmaceutical Research, 21 (1). pp. 101-7. ISSN 0724-8741

Dufès, Christine and Gaillard, Frédéric and Uchegbu, I.F. and Schätzlein, Andreas G. and Olivier, Jean-Christophe and Muller, Jean-Marc (2004) Glucose-targeted niosomes deliver vasoactive intestinal peptide (VIP) to the brain. International Journal of Pharmaceutics, 285 (1-2). pp. 77-85. ISSN 1873-3476

2003

Dufès, Christine and Olivier, Jean-Christophe and Gaillard, Frédéric and Gaillard, Afsaneh and Couet, William and Muller, Jean-Marc (2003) Brain delivery of vasoactive intestinal peptide (VIP) following nasal administration to rats. International Journal of Pharmaceutics, 255 (1-2). pp. 87-97. ISSN 1873-3476

Dufès, Christine and Alleaume, Céline and Montoni, Alicia and Olivier, Jean-Christophe and Muller, Jean-Marc (2003) Effects of the vasoactive intestinal peptide (VIP) and related peptides on glioblastoma cell growth in vitro. Journal of Molecular Neuroscience, 21 (2). pp. 91-102. ISSN 0895-8696

2000

McPhail, Donald and Tetley, L. and Dufès, Christine and Uchegbu, I.F. (2000) Liposomes encapsulating polymeric chitosan based vesicles - a vesicle in vesicle system for drug delivery. International Journal of Pharmaceutics, 200 (1). pp. 73-86. ISSN 1873-3476

Dufès, Christine and Schätzlein, A.G. and Tetley, L. and Gray, A.I. and Watson, D.G. and Olivier, J.C. and Couet, W. and Uchegbu, I.F. (2000) Niosomes and polymeric chitosan based vesicles bearing transferrin and glucose ligands for drug targeting. Pharmaceutical Research, 17 (10). pp. 1250-1258. ISSN 0724-8741