Browse by Author or creator

2024

Abdelsalam, Aisha A. Abdelati and Woods, Stuart and Henriquez, Selina and Curran, Lucy and Westrop, Gareth and Roberts, Craig W. (2024) Toxoplasma gondii infection of BALB/c mice perturbs host neurochemistry. Parasite Immunology, 46 (11). e13073. ISSN 0141-9838

Lykins, Joseph and Moschitto, Mathew J. and Zhou, Ying and Filippova, Ekaterina V. and Le, Hoang V. and Tomita, Tadakimi and Fox, Barbara A. and Bzik, David J. and Su, Chunlei and Rajagopala, Seesandra V. and Flores, Kristin and Spano, Furio and Woods, Stuart and Roberts, Craig W. and Hua, Cong and El Bissati, Kamal and Wheeler, Kelsey M. and Dovgin, Sarah and Muench, Stephen P. and McPhillie, Martin and Fishwick, Colin W.G. and Anderson, Wayne F. and Lee, Patricia J. and Hickman, Mark and Weiss, Louis M. and Dubey, Jitender P. and Lorenzi, Hernan A. and Silverman, Richard B. and McLeod, Rima L. (2024) From TgO/GABA-AT, GABA, and T-263 mutant to conception of Toxoplasma. iScience, 27 (1). 108477. ISSN 2589-0042

2022

Anderluzzi, Giulia and Lou, Gustavo and Woods, Stuart and Schmidt, Signe Tandrup and Gallorini, Simona and Brazzoli, Michela and Johnson, Russell and Roberts, Craig W. and O'Hagan, Derek T. and Baudner, Barbara C. and Perrie, Yvonne (2022) The role of nanoparticle format and route of administration on self-amplifying mRNA vaccine potency. Journal of Controlled Release, 342. pp. 388-399. ISSN 0168-3659

Meewan, Jitkasem and Somani, Sukrut and Laskar, Partha and Irving, Craig and Mullin, Margaret and Woods, Stuart and Roberts, Craig W. and Alzahrani, Abdullah R. and Ferro, Valerie A. and McGill, Suzanne and Weidt, Stefan and Burchmore, Richard and Dufès, Christine (2022) Limited impact of the protein corona on the cellular uptake of PEGylated zein micelles by melanoma cancer cells. Pharmaceutics, 14 (2). 439. ISSN 1999-4923

2021

Brozio, Sarah and O’Shaughnessy, Erin M. and Woods, Stuart and Hall-Barrientos, Ivan and Martin, Patricia E. and Kennedy, Malcolm W. and Lamprou, Dimitrios A. and Hoskisson, Paul A. (2021) Frog nest foams exhibit pharmaceutical foam-like properties. Royal Society Open Science, 8 (9). 210048. ISSN 2054-5703

Alonaizan, Rasha and Woods, Stuart and Hargrave, Kerrie E and Roberts, Craig W. (2021) An exaggerated immune response in female BALB/c mice controls initial Toxoplasma gondii multiplication but increases mortality and morbidity relative to male mice. Pathogens, 10 (9). 1154.

Anderluzzi, Giulia and Schmidt, Signe Tandrup and Cunliffe, Robert and Woods, Stuart and Roberts, Craig W. and Veggi, Daniele and Ferlenghi, Ilaria and O'Hagan, Derek T. and Baudner, Barbara C. and Perrie, Yvonne (2021) Rational design of adjuvants for subunit vaccines : the format of cationic adjuvants affects the induction of antigen-specific antibody responses. Journal of Controlled Release, 330. pp. 933-944. ISSN 0168-3659

2020

Lou, Gustavo and Anderluzzi, Giulia and Schmidt, Signe Tandrup and Woods, Stuart and Gallorini, Simona and Brazzoli, Michela and Giusti, Fabiola and Ferlenghi, Ilaria and Johnson, Russell N. and Roberts, Craig W. and O'Hagan, Derek T. and Baudner, Barbara C. and Perrie, Yvonne (2020) Delivery of self-amplifying mRNA vaccines by cationic lipid nanoparticles : the impact of cationic lipid selection. Journal of Controlled Release, 325. pp. 370-379. ISSN 0168-3659

Woods, Stuart and O'Brien, Lyn M. and Butcher, Wendy and Preston, Jane E. and Georgian, Ana R. and Williamson, E. Diane and Salguero, F. Javier and Modino, Francesca and Abbott, N. Joan and Roberts, Craig W. and D'Elia, Riccardo V. (2020) Glucosamine-NISV delivers antibody across the blood-brain barrier : optimization for treatment of encephalitic viruses. Journal of Controlled Release, 324. pp. 644-656. ISSN 0168-3659

Chatzikleanthous, Despo and Schmidt, Signe Tandrup and Buffi, Giada and Paciello, Ida and Cunliffe, Robert and Carboni, Filippo and Romano, Maria Rosaria and O'Hagan, Derek T. and D'Oro, Ugo and Woods, Stuart and Roberts, Craig W. and Perrie, Yvonne and Adamo, Roberto (2020) Design of a novel vaccine nanotechnology-based delivery system comprising CpGODN-protein conjugate anchored to liposomes. Journal of Controlled Release, 323. pp. 125-137. ISSN 0168-3659

McPhillie, Martin J and Zhou, Ying and Hickman, Mark R and Gordon, James A. and Weber, Christopher R. and Li, Qigui and Lee, Patty J. and Amporndanai, Kangsa and Johnson, Rachel M. and Darby, Heather and Woods, Stuart and Li, Zhu-hong and Priestley, Richard S. and Ristroph, Kurt D. and Biering, Scott B. and El Bissati, Kamal and Hwang, Seungmin and Hakim, Farida Esaa and Dovgin, Sarah M. and Lykins, Joseph D. and Roberts, Lucy and Hargrave, Kerrie and Cong, Hua and Sinai, Anthony P. and Muench, Stephen P. and Dubey, Jitender P. and Prud'homme, Robert K. and Lorenzi, Hernan A. and Biagini, Giancarlo A. and Moreno, Silvia N. and Roberts, Craig W. and Antonyuk, Svetlana V. and Fishwick, Colin W. G. and McLeod, Rima (2020) Potent tetrahydroquinolone eliminates apicomplexan parasites. Frontiers in Cellular and Infection Microbiology : Parasite and Host, 10. 203. ISSN 2235-2988

2019

Lou, Gustavo and Anderluzzi, Giulia and Woods, Stuart and Roberts, Craig W. and Perrie, Yvonne (2019) A novel microfluidic-based approach to formulate size-tuneable large unilamellar cationic liposomes : formulation, cellular uptake and biodistribution investigations. European Journal of Pharmaceutics and Biopharmaceutics, 143. pp. 51-60. ISSN 0939-6411

Hargrave, Kerrie E. and Woods, Stuart and Millington, Owain and Chalmers, Susan and Westrop, Gareth D. and Roberts, Craig W. (2019) Multi-omics studies demonstrate Toxoplasma gondii-induced metabolic reprogramming of murine dendritic cells. Frontiers in Cellular and Infection Microbiology : Parasite and Host, 9. 309. ISSN 2235-2988

D'Elia, Riccardo V. and Woods, Stuart and Butcher, Wendy and McGahon, Jonathan and Khadke, Swapnil and Perrie, Yvonne and Williamson, E. Diane and Roberts, Craig W. (2019) Exploitation of the bilosome platform technology to formulate antibiotics and enhance efficacy of melioidosis treatments. Journal of Controlled Release, 298. pp. 202-212. ISSN 0168-3659

Schroeder, Juliane and Ross, Kirsty and McIntosh, Kathryn and Jabbar, Shilan Khayrula Jabbar and Woods, Stuart and Crowe, Jenny and Patterson-Kane, Janet C and Alexander, James and Lawrence, Catherine and Plevin, Robin (2019) Novel protective role for MAP kinase phosphatase 2 in inflammatory arthritis. RMD Open, 5 (1). e000711. e000711. ISSN 2056-5933

2018

Lykins, Joseph D. and Filippova, Ekaterina V. and Halavaty, Andrei S. and Minasova, George and Zhou, Ying and Dubrovska, Ievgeniia and Flores, Kristin J. and Shuvalova, Ludmilla A. and Ruan, Jiapeng and El Bissati, Kamal and Dovgin, Sarah and Roberts, Craig W. and Woods, Stuart and Moulton, Jon D. and Moulton, Hong and McPhillie, Martin J. and Muench, Stephen P. and Fishwick, Colin W. G. and Sabini, Elisabetta and Shanmugam, Dhanasekaran and Roos, David S. and McLeod, Rima and Anderson, Wayne F. and Ngô, Huân M (2018) CSGID solves structures and identifies phenotypes for five enzymes in Toxoplasma gondii. Frontiers in Cellular and Infection Microbiology : Parasite and Host, 8. 352.

2017

Gras, Simon and Jackson, Allison and Woods, Stuart and Pall, Gurman and Whitelaw, Jamie and Leung, Jacqueline M. and Ward, Gary E. and Roberts, Craig W. and Meissner, Markus (2017) Parasites lacking the micronemal protein MIC2 are deficient in surface attachment and host cell egress, but remain virulent in vivo. Wellcome Open Research, 2. 32. ISSN 2398-502X

Cano, Antonella and Mattana, Antonella and Woods, Stuart and Henriquez, Fiona L. and Alexander, James and Roberts, Craig W. (2017) Acanthamoeba activates macrophages predominantly through toll-like receptor 4 and MyD88-dependent mechanisms to induce Interleukin IL-12 and IL-6. Infection and Immunity, 85 (6). e01054-16. ISSN 0019-9567

2016

El Bissati, Kamal and Chentoufi, Aziz A and Krishack, Paulette A and Zhou, Ying and Woods, Stuart and Dubey, Jitender P and Vang, Lo and Lykins, Joseph and Broderick, Kate E and Mui, Ernest and Suzuki, Yasuhiro and Sa, Qila and Bi, Stephanie and Cardona, Nestor and Verma, Shiv K and Frazeck, Laura and Reardon, Catherine A and Sidney, John and Alexander, Jeff and Sette, Alessandro and Vedvick, Tom and Guderian, Jeffrey A and Reed, Steven and Roberts, Craig W (2016) Adjuvanted multi-epitope vaccines protect HLA-A*11:01 transgenic mice against Toxoplasma gondii. JCI Insight, 1 (15). e85955. ISSN 2379-3708

McPhillie, Martin and Zhou, Ying and El Bissati, Kamal and Dubey, Jitender and Lorenzi, Hernan and Capper, Michael and Lukens, Amanda K and Hickman, Mark and Muench, Stephen and Verma, Shiv Kumar and Weber, Christopher R. and Wheeler, Kelsey and Gordon, James and Sanders, Justin and Moulton, Hong and Wang, Kai and Kim, Taek-Kyun and He, Yuqing and Santos, Tatiana and Woods, Stuart and Lee, Patty and Donkin, David and Kim, Eric and Fraczek, Laura and Lykins, Joseph and Esaa, Farida and Alibana-Clouser, Fatima and Dovgin, Sarah and Weiss, Louis and Brasseur, Gael and Wirth, Dyann and Kent, Michael and Hood, Leroy and Meunieur, Brigitte and Roberts, Craig W. and Hasnain, S. Samar and Antonyuk, Svetlana V. and Fishwick, Colin and McLeod, Rima (2016) New paradigms for understanding and step changes in treating active and chronic, persistent apicomplexan infections. Scientific Reports, 6. pp. 1-23. 29179. ISSN 2045-2322

2014

Wilkinson, Craig and McPhillie, Martin J and Zhou, Ying and Woods, Stuart and Afanador, Gustavo A and Rawson, Shaun and Khaliq, Farzana and Prigge, Sean T and Roberts, Craig W and Rice, David W and McLeod, Rima and Fishwick, Colin W and Muench, Stephen P (2014) The benzimidazole based drugs show good activity against T. gondii but poor activity against its proposed enoyl reductase enzyme target. Bioorganic and Medicinal Chemistry Letters, 24 (3). pp. 911-916. ISSN 0960-894X

2013

Woods, Stuart and Schroeder, Juliane and McGachy, Helen A and Plevin, Robin and Roberts, Craig W and Alexander, James (2013) MAP kinase phosphatase-2 plays a key role in the control of infection with Toxoplasma gondii by modulating iNOS and arginase-1 activities in mice. PLOS Pathogens, 9 (8). e1003535.

Stec, Jozef and Fomovska, Alina and Afanador, Gustavo A. and Muench, Stephen P. and Zhou, Ying and Lai, Bo Shiun and ElBissati, Kamal and Hickman, Mark R. and Lee, Patty J. and Leed, Susan E. and Auschwitz, Jennifer M. and Sommervile, Caroline and Woods, Stuart and Roberts, Craig W. and Rice, David and Prigge, Sean T. and Mcleod, Rima and Kozikowski, Alan P. (2013) Modification of triclosan scaffold in search of improved inhibitors for enoyl-acyl carrier protein (ACP) reductase in Toxoplasma gondii. ChemMedChem, 8 (7). pp. 1138-1160. ISSN 1860-7179

Cheng, Gang and Muench, Stephen P and Zhou, Ying and Afanador, Gustavo A and Mui, Ernest J and Fomovska, Alina and Lai, Bo Shiun and Prigge, Sean T and Woods, Stuart and Roberts, Craig W and Hickman, Mark R and Lee, Patty J and Leed, Susan E and Auschwitz, Jennifer M and Rice, David W and McLeod, Rima (2013) Design, synthesis, and biological activity of diaryl ether inhibitors of Toxoplasma gondii enoyl reductase. Bioorganic and Medicinal Chemistry Letters, 23 (7). pp. 2035-2043. ISSN 0960-894X

Schroeder, Juliane and McGachy, H Adrienne and Woods, Stuart and Plevin, Robin and Alexander, James (2013) T cell hypo-responsiveness against Leishmania major in MAP kinase phosphatase (MKP) 2 deficient C57BL/6 mice does not alter the healer disease phenotype. PLOS Neglected Tropical Diseases, 7 (2). e2064.

2012

Fomovska, Alina and Wood, Richard D. and Mui, Ernest and Dubey, Jitenter P. and Ferreira, Leandra R. and Hickman, Mark R. and Lee, Patricia J. and Leed, Susan E. and Auschwitz, Jennifer M. and Welsh, William J. and Sommerville, Caroline and Woods, Stuart and Roberts, Craig and Mcleod, Rima (2012) Salicylanilide inhibitors of toxoplasma gondii. Journal of Medicinal Chemistry, 55 (19). pp. 8375-8391. ISSN 0022-2623

Cong, Hua and Mui, Ernest J and Witola, William H and Sidney, John and Alexander, Jeff and Sette, Alessandro and Maewal, Ajesh and El Bissati, Kamal and Zhou, Ying and Suzuki, Yasuhiro and Lee, Daniel and Woods, Stuart and Sommerville, Caroline and Henriquez, Fiona and Roberts, Craig and McLeod, Rima (2012) Toxoplasma gondii HLA-B(⁎)0702-restricted GRA7(20-28) peptide with adjuvants and a universal helper T cell epitope elicits CD8(+) T cells producing interferon-γ and reduces parasite burden in HLA-B(⁎)0702 mice. Human Immunology, 73 (1). pp. 1-10.

2010

Henriquez, Fiona L. and Woods, Stuart and Cong, Hua and McLeod, Rima and Roberts, Craig (2010) Immunogenetics of toxoplasma gondii informs vaccine design. Trends in Parasitology, 26 (11). pp. 550-555. ISSN 1471-4922