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2024

Abuhassan, Qamar and Silva, Maria Inês and Abu-Rajab Tamimi, Rana and Khadra, Ibrahim and Batchelor, Hannah K. and Pyper, Kate and Halbert, Gavin W. (2024) A novel simulated media system for in vitro evaluation of bioequivalent intestinal drug solubility. European Journal of Pharmaceutics and Biopharmaceutics, 199. 114302. ISSN 0939-6411

2023

Silva, Maria Inês and Khadra, Ibrahim and Pyper, Kate and Halbert, Gavin W. (2023) Structured solubility behaviour in fed simulated intestinal fluids. European Journal of Pharmaceutics and Biopharmaceutics, 193. pp. 58-73. ISSN 0939-6411

Goelen, Jan and Farrell, Gillian and McGeehan, Jonathan and Titman, Christopher M. and Rattray, Nicholas J.W. and Johnson, Trevor N. and Horniblow, Richard D. and Batchelor, Hannah K. (2023) Quantification of drug metabolising enzymes and transporter proteins in the paediatric duodenum via LC-MS/MS proteomics using a QconCAT technique. European Journal of Pharmaceutics and Biopharmaceutics, 191. pp. 68-77. ISSN 0939-6411

Silva, Maria Inês and Khadra, Ibrahim and Pyper, Kate and Halbert, Gavin W. (2023) Fed intestinal solubility limits and distributions applied to the developability classification system. European Journal of Pharmaceutics and Biopharmaceutics, 186. pp. 74-84. ISSN 0939-6411

2022

Silva, Maria Inês and Khadra, Ibrahim and Pyper, Kate and Halbert, Gavin W. (2022) Small scale in vitro method to determine a potential bioequivalent equilibrium solubility range for fed human intestinal fluid. European Journal of Pharmaceutics and Biopharmaceutics, 177. pp. 126-134. ISSN 0939-6411

Abuhassan, Qamar and Khadra, Ibrahim and Pyper, Kate and Augustijns, Patrick and Brouwers, Joachim and Halbert, Gavin W. (2022) Structured solubility behaviour in bioequivalent fasted simulated intestinal fluids. European Journal of Pharmaceutics and Biopharmaceutics, 176. pp. 108-121. ISSN 0939-6411

Gebril, Ayman and Obeid, Mohammad A. and Bennett, Ewan M. and Pujol, Anairis and Chovel, Mario L. and Mahy, Tatiana and Acevedo, Reinaldo and Ferro, Valerie A. (2022) Mucosal and systemic immune responses following mucosal immunisation of tetanus toxoid entrapped in lipid nanoparticles prepared by microwave reactor. European Journal of Pharmaceutics and Biopharmaceutics, 171. pp. 11-18. ISSN 0939-6411

Abuhassan, Qamar and Khadra, Ibrahim and Pyper, Kate and Augustijns, Patrick and Brouwers, Joachim and Halbert, Gavin W. (2022) Fasted intestinal solubility limits and distributions applied to the biopharmaceutics and developability classification systems. European Journal of Pharmaceutics and Biopharmaceutics, 170. pp. 160-169. ISSN 0939-6411

2021

Abuhassan, Qamar and Khadra, Ibrahim and Pyper, Kate and Halbert, Gavin W. (2021) Small scale in vitro method to determine a bioequivalent equilibrium solubility range for fasted human intestinal fluid. European Journal of Pharmaceutics and Biopharmaceutics, 168. pp. 90-96. ISSN 0939-6411

Pawar, Gopal and Papadatou-Soulou, Eleni and Mason, Julie and Muhammed, Rafeeq and Watson, Alison and Cotter, Catherine and Abdullah, Mohammed and Harrad, Stuart and Mackie, Claire and Arien, Tina and Inghelbrecht, Sabine and Batchelor, Hannah (2021) Characterisation of fasted state gastric and intestinal fluids collected from children. European Journal of Pharmaceutics and Biopharmaceutics, 158. pp. 156-165. ISSN 0939-6411

Batchelor, Hannah (2021) Determination of healthcare resource and cost implications of using alternative sodium valproate formulations in the treatment of epilepsy in children in England : a retrospective database review. European Journal of Pharmaceutics and Biopharmaceutics, 158. pp. 365-370. ISSN 0939-6411

2020

Pyper, Kate and Brouwers, Joachim and Augustijns, Patrick and Khadra, I. and Dunn, C. and Wilson, C.G. and Halbert, G.W. (2020) Multidimensional analysis of human intestinal fluid composition. European Journal of Pharmaceutics and Biopharmaceutics, 153. pp. 226-240. ISSN 0939-6411

McPherson, Stephanie and Perrier, Jeremy and Dunn, Claire and Khadra, Ibrahim and Davidson, Scott and Ainousah, Bayan and Wilson, Clive G. and Halbert, Gavin (2020) Small scale design of experiment investigation of equilibrium solubility in simulated fasted and fed intestinal fluid. European Journal of Pharmaceutics and Biopharmaceutics, 150. pp. 14-23. ISSN 0939-6411

Etherson, Kelly and Dunn, Claire and Matthews, Wayne and Pamelund, Henrik and Barragat, Camille and Sanderson, Natalie and Izumi, Toshiko and da Costa Mathews, Claudia and Halbert, Gavin and Wilson, Clive and McAllister, Mark and Mann, James and Østergaard, Jesper and Butler, James and Khadra, Ibrahim (2020) An interlaboratory investigation of intrinsic dissolution rate determination using surface dissolution. European Journal of Pharmaceutics and Biopharmaceutics, 150. pp. 24-32. ISSN 0939-6411

2019

Lou, Gustavo and Anderluzzi, Giulia and Woods, Stuart and Roberts, Craig W. and Perrie, Yvonne (2019) A novel microfluidic-based approach to formulate size-tuneable large unilamellar cationic liposomes : formulation, cellular uptake and biodistribution investigations. European Journal of Pharmaceutics and Biopharmaceutics, 143. pp. 51-60. ISSN 0939-6411

Freerks, Lisa and Papadatou Soulou, Eleni and Batchelor, Hannah and Klein, Sandra (2019) A review of GI conditions critical to oral drug absorption in malnourished children. European Journal of Pharmaceutics and Biopharmaceutics, 137. pp. 9-22. ISSN 0939-6411

2017

Miriyala, Nikhila and Ouyang, Defang and Perrie, Yvonne and Lowry, Deborah and Kirby, Daniel J. (2017) Activated carbon as a carrier for amorphous drug delivery : effect of drug characteristics and carrier wettability. European Journal of Pharmaceutics and Biopharmaceutics, 115. pp. 197-205. ISSN 0939-6411

2016

Stamatopoulos, Konstantinos and Batchelor, Hannah K. and Simmons, Mark J.H. (2016) Dissolution profile of theophylline modified release tablets, using a biorelevant Dynamic Colon Model (DCM). European Journal of Pharmaceutics and Biopharmaceutics, 108. pp. 9-17. ISSN 0939-6411

2015

Islam, Muhammad T. and Scoutaris, Nikolaos and Maniruzzaman, Mohammed and Moradiya, Hiren G. and Halsey, Sheelagh A. and Bradley, Michael S.A. and Chowdhry, Babur Z. and Snowden, Martin J. and Douroumis, Dennis (2015) Implementation of transmission NIR as a PAT tool for monitoring drug transformation during HME processing. European Journal of Pharmaceutics and Biopharmaceutics, 96. pp. 106-116. ISSN 0939-6411

Al-Khattawi, Ali and Koner, Jasdip and Rue, Peter and Kirby, Dan and Perrie, Yvonne and Rajabi-Siahboomi, Ali and Mohammed, Afzal R. (2015) A pragmatic approach for engineering porous mannitol and mechanistic evaluation of particle performance. European Journal of Pharmaceutics and Biopharmaceutics, 94. pp. 1-10. ISSN 0939-6411

2014

Gomaa, Yasmine A. and Garland, Martin J. and McInnes, Fiona J. and Donnelly, Ryan F. and El-Khordagui, Labiba K. and Wilson, Clive G. (2014) Microneedle/nanoencapsulation-mediated transdermal delivery : mechanistic insights. European Journal of Pharmaceutics and Biopharmaceutics, 86 (2). pp. 145-155. ISSN 0939-6411

2012

Ganesan, Ashok and Watkinson, Allan and Moore, Barry (2012) Biophysical characterisation of thermal-induced precipitates of recombinant anthrax protective antigen : evidence for kinetically trapped unfolding domains in solid-state. European Journal of Pharmaceutics and Biopharmaceutics, 82 (3). 475–484. ISSN 0939-6411

Mains, Jenifer and Tan, Lay Ean and Wilson, Clive and Urquhart, Andrew (2012) A pharmacokinetic study of a combination of beta adrenoreceptor antagonists : In the isolated perfused ovine eye. European Journal of Pharmaceutics and Biopharmaceutics, 80 (2). pp. 393-401. ISSN 0939-6411

2011

Mains, Jenifer and Wilson, Clive and Urquhart, Andrew (2011) ToF-SIMS analysis of ocular tissues reveals biochemical differentiation and drug distribution. European Journal of Pharmaceutics and Biopharmaceutics, 79 (2). 328–333. ISSN 0939-6411

Ghimire, Manish and Hodges, Lee Ann and Band, Janet and Lindsay, Blythe and O'Mahony, Bridget and McInnes, Fiona J and Mullen, Alexander B and Stevens, Howard N E (2011) Correlation between in vitro and in vivo erosion behaviour of erodible tablets using gamma scintigraphy. European Journal of Pharmaceutics and Biopharmaceutics, 77 (1). pp. 148-157.

2010

Sharma, G. and Wilson, K. and van der Walle, C. F. and Sattar, N. and Petrie, J. R. and Kumar, M. N. V. Ravi (2010) Microemulsions for oral delivery of insulin : design, development and evaluation in streptozotocin induced diabetic rats. European Journal of Pharmaceutics and Biopharmaceutics, 76 (2). pp. 159-169. ISSN 0939-6411

Kek, W.K. and Miller, J. and Rawson-Lax, E. and Wilson, C.G. and Uttamchandani, D.G. (2010) In situ measurement of spectral changes in the anterior eye following application of ultraviolet-absorbing compounds. European Journal of Pharmaceutics and Biopharmaceutics, 75 (2). pp. 200-205. ISSN 0939-6411

Goodman, Kirsteen and Hodges, Lee Ann and Band, Janet and Stevens, Howard and Weitschies, Werner and Wilson, Clive (2010) Assessing gastrointestinal motility and disintegration profiles of magnetic tablets by a novel magnetic imaging device and gamma scintigraphy. European Journal of Pharmaceutics and Biopharmaceutics, 74 (1). pp. 84-92. ISSN 0939-6411

Meidan, V.M. and Pritchard, D. (2010) A two-layer diffusive model for describing the variability of transdermal drug permeation. European Journal of Pharmaceutics and Biopharmaceutics, 74 (3). pp. 513-517. ISSN 0939-6411

2009

Puapermpoonsin, U. and Spencer, J. and van der Walle, Christopher F. (2009) A freeze-dried formulation of bacteriophage encapsulated in biodegradable microspheres. European Journal of Pharmaceutics and Biopharmaceutics, 72 (1). pp. 26-33. ISSN 0939-6411

2008

Wilson, Clive and Garbacz, Grzegorz and Wedemeyer, Ralph-Steven and Nagel, Stefan and Giessmann, Thomas and Mönnikes, Hubert and Siegmund, Werner and Weitschiesa, Werner (2008) Irregular absorption profiles observed from diclofenac extended release tablets can be predicted using a dissolution apparatus that mimics in vivo stresses. European Journal of Pharmaceutics and Biopharmaceutics, 70 (2). pp. 421-428. ISSN 0939-6411

2007

Frum, Y. and Eccleston, G.M. and Meidan, V.M. (2007) Evidence that drug flux across synthetic membranes is described by normally distributed permeability coefficients. European Journal of Pharmaceutics and Biopharmaceutics, 67 (2). pp. 434-439. ISSN 0939-6411

Ghimire, M. and McInnes, F.J. and Watson, D.G. and Mullen, A. and Stevens, H. (2007) In-vitro / in-vivo correlation of pulsatile drug release from press coated tablet formulations: a pharmacoscintigraphic study in the beagle dog. European Journal of Pharmaceutics and Biopharmaceutics, 67 (2). pp. 515-523. ISSN 0939-6411

2004

McConville, Jason T and Ross, A. and Chambers, A.R. and Smith, G. and Florence, A.J. and Stevens, H. (2004) The effect of wet granulation on the erosion behaviour of an HPMC-lactose tablet, used as a rate-controlling component in a pulsatile drug delivery capsule formulation. European Journal of Pharmaceutics and Biopharmaceutics, 57 (3). pp. 541-549. ISSN 0939-6411