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Number of items: 128.

2023

Silva, Maria Inês and Khadra, Ibrahim and Pyper, Kate and Halbert, Gavin W. (2023) Structured solubility behaviour in fed simulated intestinal fluids. European Journal of Pharmaceutics and Biopharmaceutics, 193. pp. 58-73. ISSN 0939-6411

McKinnon, Zoe and Batchelor, Hannah and Khadra, Ibrahim and Halbert, Gavin (2023) Study of in vitro poorly soluble drug solubility into fasted state simulated intestinal fluid reflective of in vivo gastrointestinal variability. British Journal of Pharmacy, 8 (2). 1380. ISSN 2058-8356

Ainousah, Bayan E. and Khadra, Ibrahim and Halbert, Gavin W. (2023) Excipients impact on fenofibrate equilibrium solubility in fasted and fed simulated intestinal fluids assessed using a design of experiment protocol. Pharmaceutics, 15 (10). 2484. ISSN 1999-4923

Prasad, Elke and Robertson, John and Florence, Alastair J. and Halbert, Gavin W. (2023) Expanding the pharmaceutical formulation space in material extrusion 3D printing applications. Additive Manufacturing, 77. 103803. ISSN 2214-8604

Urwin, Stephanie J. and Chong, Magdalene W.S. and Li, Wei and McGinty, John and Mehta, Bhavik and Ottoboni, Sara and Pathan, Momina and Prasad, Elke and Robertson, Murray and McGowan, Mark and al-Attili, Mais and Gramadnikova, Ekaterina and Siddique, Mariam and Houson, Ian and Feilden, Helen and Benyahia, Brahim and Brown, Cameron J. and Halbert, Gavin W. and Johnston, Blair and Nordon, Alison and Price, Chris J. and Reilly, Chris D. and Sefcik, Jan and Florence, Alastair J. (2023) Digital process design to define and deliver pharmaceutical particle attributes. Chemical Engineering Research and Design, 196. pp. 726-749. ISSN 0263-8762

Silva, Maria Inês and Khadra, Ibrahim and Pyper, Kate and Halbert, Gavin W. (2023) Fed intestinal solubility limits and distributions applied to the developability classification system. European Journal of Pharmaceutics and Biopharmaceutics, 186. pp. 74-84. ISSN 0939-6411

Hou, P. and Besenhard, M.O. and Halbert, G. and Naftaly, M. and Markl, D. (2023) Development and implementation of a pneumatic micro-feeder for poorly-flowing solid pharmaceutical materials. International Journal of Pharmaceutics, 635. 122691. ISSN 0378-5173

Halbert, Gavin and Inês Silva, Maria and Abuhassan, Qamar and Khadra, Ibrahim and Pyper, Kate and Augustijns, Patrick and Brouwer, Joachim (2023) Acidic drugs - intestinal solubility correlation fasted and fed in vitro vs ex vivo. In: 4th European Conference on Pharmaceutics, 2023-03-20 - 2023-03-21, Palais des Congrés.

2022

Paladino, Eleonora and Doerr, Frederik J.S. and Bordos, Ecaterina and Onyemelukwe, Iyke I. and Lamprou, Dimitrios A. and Florence, Alastair J. and Gilmore, Ian S. and Halbert, Gavin W. (2022) High spatial resolution ToF-SIMS imaging and image analysis strategies to monitor and quantify early phase separation in amorphous solid dispersions. International Journal of Pharmaceutics, 628. 122191. ISSN 0378-5173

McKinnon, Zoe and Batchelor, Hannah and Khadra, Ibrahim and Halbert, Gavin (2022) Solubility measurement of poorly soluble drugs in fasted state simulated intestinal fluid. British Journal of Pharmacy, 7 (2). ISSN 2058-8356

Prasad, Elke and Robertson, John and Halbert, Gavin W. (2022) Identifying the operating space and repeatability of a novel filament free FDM printer. In: AAPS 2022 Pharm Sci 360, 2022-10-16 - 2022-10-19, USA.

Prasad, Elke and Robertson, John and Halbert, Gavin W. (2022) Printability of pharmaceutical Fused Deposition Modeling (FDM) feedstock material : mechanical characterisation of FDM filaments and the FDM 3D printing process. In: AAPS 2022 Pharm Sci 360, 2022-10-16 - 2022-10-19, USA.

Jolliffe, Hikaru G. and Ojo, Ebenezer and Mendez Torrecillas, Carlota and Houson, Ian and Elkes, Richard and Reynolds, Gavin and Kong, Angela and Meehan, Elizabeth and Becker, Felipe Amado and Piccione, Patrick M. and Verma, Sudhir and Singaraju, Aditya and Halbert, Gavin and Robertson, John (2022) Linked experimental and modelling approaches for tablet property predictions. International Journal of Pharmaceutics, 626. 122116. ISSN 0378-5173

Osouli-Bostanabad, Karim and Puliga, Sara and Serrano, Dolores R. and Bucchi, Andrea and Halbert, Gavin and Lalatsa, Aikaterini (2022) Microfluidic manufacture of lipid-based nanomedicines. Pharmaceutics, 14 (9). 1940. ISSN 1999-4923

Silva, Maria Inês and Khadra, Ibrahim and Pyper, Kate and Halbert, Gavin W. (2022) Small scale in vitro method to determine a potential bioequivalent equilibrium solubility range for fed human intestinal fluid. European Journal of Pharmaceutics and Biopharmaceutics, 177. pp. 126-134. ISSN 0939-6411

Walsh, Erin and Maclean, Natalie and Turner, Alice and Alsuleman, Moulham and Prasad, Elke and Halbert, Gavin and ter Horst, Joop H. and Markl, Daniel (2022) Manufacture of tablets with structurally-controlled drug release using rapid tooling injection moulding. International Journal of Pharmaceutics, 624. 121956. ISSN 0378-5173

Abuhassan, Qamar and Khadra, Ibrahim and Pyper, Kate and Augustijns, Patrick and Brouwers, Joachim and Halbert, Gavin W. (2022) Structured solubility behaviour in bioequivalent fasted simulated intestinal fluids. European Journal of Pharmaceutics and Biopharmaceutics, 176. pp. 108-121. ISSN 0939-6411

Polyzois, Hector and Guo, Rui and Srirambhatla, Vijay K. and Warzecha, Monika and Prasad, Elke and Turner, Alice and Halbert, Gavin W. and Keating, Patricia and Price, Sarah L. and Florence, Alastair J. (2022) Crystal structure and twisted aggregates of oxcarbazepine form III. Crystal Growth and Design, 22 (7). pp. 4146-4156. ISSN 1528-7483

Eschweiler, Simon and Ramírez-Suástegui, Ciro and Li, Yingcong and King, Emma and Chudley, Lindsey and Thomas, Jaya and Wood, Oliver and von Witzleben, Adrian and Jeffrey, Danielle and McCann, Katy and Simon, Hayley and Mondal, Monalisa and Wang, Alice and Dicker, Martina and Lopez-Guadamillas, Elena and Chou, Ting-Fang and Dobbs, Nicola A and Essame, Louisa and Acton, Gary and Kelly, Fiona and Halbert, Gavin and Sacco, Joseph J and Schache, Andrew Graeme and Shaw, Richard and McCaul, James Anthony and Paterson, Claire and Davies, Joseph H and Brennan, Peter A and Singh, Rabindra P and Loadman, Paul M and Wilson, William and Hackshaw, Allan and Seumois, Gregory and Okkenhaug, Klaus and Thomas, Gareth J and Jones, Terry M and Ay, Ferhat and Friberg, Greg and Kronenberg, Mitchell and Vanhaesebroeck, Bart and Vijayanand, Pandurangan and Ottensmeier, Christian H (2022) Intermittent PI3Kδ inhibition sustains anti-tumour immunity and curbs irAEs. Nature, 605 (7911). 741–746. ISSN 0028-0836

Vivattanaseth, Pattavet and Chong, Magdalene and Prasad, Elke and Halbert, Gavin and Robertson, John and McFarlan, Catriona and Nordon, Alison (2022) Application of multivariate curve resolution to in situ THz - Raman spectroscopy of amorphous solid dispersions in pharmaceutical products. In: CMAC Annual Open Day 2022, 2022-05-16 - 2022-05-18.

Chong, Magdalene and Brown, Cameron and Mustoe, Chantal and McGinty, John and Li, Wei and Pathan, Momina and Ottoboni, Sara and Prasad, Elke and Robertson, Murray and Mehta, Bhavik and McGowan, Mark and Siddique, Humera and Raval, Vishal and Pereira Diaz, Laura and Siddique, Mariam and Eales, William and Turner, Alice and Johnston, Blair and Robertson, John and Halbert, Gavin and Price, Chris and Benyahia, Brahim and Rielly, Chris and Sefcik, Jan and Nordon, Alison and McGlone, Thomas and Smith, Kenneth and Feilden, Helen and Houson, Ian and Florence, Alastair (2022) The CMAC MicroFactory : mefenamic acid. In: CMAC Annual Open Day 2022, 2022-05-16 - 2022-05-18.

Prasad, Elke and Robertson, John and Halbert, Gavin (2022) An additive manufacturing MicroFactory : overcoming limitations of pharmaceutical formulations. In: CMAC Annual Open Day 2022, 2022-05-16 - 2022-05-18.

Alsuleman, Moulham and Halbert, Gavin (2022) A story of a 3D printing filament : from a single component to a pharmaceutical 3D printing filament. In: CMAC Annual Open Day 2022, 2022-05-16 - 2022-05-18.

Prasad, Elke and Robertson, John and Halbert, Gavin W. (2022) Mefenamic acid solid dispersions : impact of formulation composition on processing parameters, product properties and performance. International Journal of Pharmaceutics, 616. 121505. ISSN 0378-5173

Abuhassan, Qamar and Khadra, Ibrahim and Pyper, Kate and Augustijns, Patrick and Brouwers, Joachim and Halbert, Gavin W. (2022) Fasted intestinal solubility limits and distributions applied to the biopharmaceutics and developability classification systems. European Journal of Pharmaceutics and Biopharmaceutics, 170. pp. 160-169. ISSN 0939-6411

2021

Abuhassan, Qamar and Khadra, Ibrahim and Pyper, Kate and Halbert, Gavin W. (2021) Small scale in vitro method to determine a bioequivalent equilibrium solubility range for fasted human intestinal fluid. European Journal of Pharmaceutics and Biopharmaceutics, 168. pp. 90-96. ISSN 0939-6411

Prasad, Elke and Robertson, John and Halbert, Gavin W. (2021) Solid dispersions : improving drug performance through tablet micro-structure design. In: American Association of Pharmaceutical Scientists 2021, 2021-10-17 - 2021-10-20, Boston Convention & Exhibition Center.

Prasad, Elke and Halbert, Gavin and Robertson, John (2021) Opening up the pharmaceutical formulation space for Additive Manufacturing. In: EUPAT 10 (2021) pan-European Science Conference on QbD & PAT, 2021-10-04 - 2021-10-06, Virtual Conference.

Abuhassan, Qamar and Silva, Maria and Khadra, Ibrahim and Halbert, Gavin and Pyper, Kate and Brouwers, Joachim (2021) Bioequivalent Simulated Intestinal Fluid - The first segment. In: UnGap Annual Conference, 2021-09-28 - 2021-09-29, KU Leuven.

Halbert, Gavin and Prasad, Elke and Robertson, John (2021) Continuous pharmaceutical processes new applications – old challenges. In: 4th International Symposium on Pharmaceutical Engineering Research - SPheRe, 2021-09-15 - 2021-09-17, TU Braunschweig.

Prasad, Elke and Robertson, John and Halbert, Gavin W. (2021) Mechanical characterisation of an FDM 3D printing process. In: Virtual PharmSci, 2021-09-07 - 2021-09-09.

Prasad, Elke and Robertson, John and Halbert, Gavin W. (2021) Printability of pharmaceutical polymers in FDM 3D printers. In: Virtual PharmSci, 2021-09-07 - 2021-09-09.

Prasad, Elke and Robertson, John and Halbert, Gavin W. (2021) Quality control test for pharmaceutical feedstock material for FDM 3D printers. In: Virtual PharmSci, 2021-09-07 - 2021-09-09.

2020

Roces, Carla B. and Lou, Gustavo and Jain, Nikita and Abraham, Suraj and Thomas, Anitha and Halbert, Gavin W. and Perrie, Yvonne (2020) Manufacturing considerations for the development of lipid nanoparticles using microfluidics. Pharmaceutics, 12 (11). 1095. ISSN 1999-4923

Prasad, Elke and Robertson, John and Halbert, Gavin W. (2020) Improving consistency for a Mefenamic acid immediate release formulation. In: CMAC Annual Open Day, 2020-10-21 - 2020-10-22, Virtual event.

McLeod, Robert and Kumar, Rajiv and Papadatos-Pastos, Dionysis and Mateo, Joaquin and Brown, Jessica S. and Ingles Garces, Alvaro H. and Ruddle, Ruth and Decordova, Shaun and Jueliger, Simone and Ferraldeschi, Roberta and Maiques, Oscar and Sanz-Moreno, Victoria and Jones, Paul and Traub, Stephanie and Halbert, Gavin and Mellor, Sarah and Swales, Karen E. and Raynaud, Florence I. and Garrett, Michelle D. and Banerji, Udai (2020) First-in-human study of AT13148, a dual ROCK-AKT inhibitor in patients with solid tumors. Clinical Cancer Research, 26. pp. 4777-4784. ISSN 1078-0432

Pyper, Kate and Brouwers, Joachim and Augustijns, Patrick and Khadra, I. and Dunn, C. and Wilson, C.G. and Halbert, G.W. (2020) Multidimensional analysis of human intestinal fluid composition. European Journal of Pharmaceutics and Biopharmaceutics, 153. pp. 226-240. ISSN 0939-6411

Roces, Carla B. and Port, Emily Charlotte and Daskalakis, Nikolaos N. and Watts, Julie A. and Aylott, Jonathan and Halbert, Gavin and Perrie, Yvonne (2020) Rapid scale-up and production of active-loaded PEGylated liposomes. International Journal of Pharmaceutics, 586. 119566. ISSN 0378-5173

Prasad, Elke and Robertson, John and Halbert, Gavin (2020) Improving consistency for a Mefenamic acid immediate release formulation. Journal of Pharmaceutical Sciences. ISSN 0022-3549

McPherson, Stephanie and Perrier, Jeremy and Dunn, Claire and Khadra, Ibrahim and Davidson, Scott and Ainousah, Bayan and Wilson, Clive G. and Halbert, Gavin (2020) Small scale design of experiment investigation of equilibrium solubility in simulated fasted and fed intestinal fluid. European Journal of Pharmaceutics and Biopharmaceutics, 150. pp. 14-23. ISSN 0939-6411

Etherson, Kelly and Dunn, Claire and Matthews, Wayne and Pamelund, Henrik and Barragat, Camille and Sanderson, Natalie and Izumi, Toshiko and da Costa Mathews, Claudia and Halbert, Gavin and Wilson, Clive and McAllister, Mark and Mann, James and Østergaard, Jesper and Butler, James and Khadra, Ibrahim (2020) An interlaboratory investigation of intrinsic dissolution rate determination using surface dissolution. European Journal of Pharmaceutics and Biopharmaceutics, 150. pp. 24-32. ISSN 0939-6411

2019

Prasad, E. and Robertson, J. and Halbert, G. (2019) Enabling future manufacture of dose forms: screening tools for an HME-3D printing process. In: CMAC UK Showcase, 2019-10-23 - 2019-10-23, CMAC Future Manufacturing Research Hub, Strathclyde Institute of Pharmacy and Biomedical Sciences.

Bordos, Ecaterina and Islam, Muhammad T. and Florence, Alastair J. and Halbert, Gavin W. and Robertson, John (2019) Use of terahertz-Raman spectroscopy to determine solubility of the crystalline active pharmaceutical ingredient in polymeric matrices during hot melt extrusion. Molecular Pharmaceutics, 16 (10). pp. 4361-4371. ISSN 1543-8384

Prasad, Elke and Islam, Muhammad T. and Goodwin, Daniel J. and Megarry, Andrew J. and Halbert, Gavin W. and Florence, Alastair J. and Robertson, John (2019) Development of a hot-melt extrusion (HME) process to produce drug loaded Affinisol™ 15LV filaments for Fused Filament Fabrication (FFF) 3D printing. Additive Manufacturing, 29. 100776. ISSN 2214-8604

Connor, Lauren E. and Vassileiou, Antony D. and Halbert, Gavin W. and Johnston, Blair F. and Oswald, Iain D.H. (2019) Structural investigation and compression of a co-crystal of indomethacin and saccharin. CrystEngComm, 21 (30). pp. 4465-4472. ISSN 1466-8033

Jolliffe, Hikaru G. and Papathanasiou, Foteini and Prasad, Elke and Halbert, Gavin and Robertson, John and Brown, Cameron J. and Florence, Alastair J.; (2019) Improving the prediction of multi-component tablet properties from pure component parameters. In: 29th European Symposium on Computer Aided Chemical Engineering. Computer Aided Chemical Engineering, 46 . Elsevier, NLD, pp. 883-888. ISBN 9780128186350

Prasad, E. and Robertson, J. and Halbert, G. (2019) HUB Microfactory – PPA1 – Mefenamic acid – HME – 3D printing process stream. In: CMAC DTC Summer school, 2019-06-12 - 2019-06-14, Hampden Park.

Dunn, Claire and Perrier, Jeremy and Khadra, Ibrahim and Wilson, Clive G. and Halbert, Gavin W. (2019) The topography of simulated intestinal equilibrium solubility. Molecular Pharmaceutics, 16 (5). pp. 1890-1905. ISSN 1543-8384

Khadra, Ibrahim and Obeid, Mohammad A. and Dunn, Claire and Watts, Stewart and Halbert, Gavin and Ford, Steven and Mullen, Alexander (2019) Characterisation and optimisation of diclofenac sodium orodispersible thin film formulation. International Journal of Pharmaceutics, 561. pp. 43-46. ISSN 0378-5173

2018

Torrecillas, Carlota Mendez and Gorringe, Lee J. and Rajoub, Nazer and Robertson, John and Elkes, Richard G. and Lamprou, Dimitrios A. and Halbert, Gavin W. (2018) The impact of channel fill level on internal forces during continuous twin screw wet granulation. International Journal of Pharmaceutics. pp. 1-43. ISSN 0378-5173

Prasad, E. and Robertson, J. and Brown, C. and Jolliffe, H. and Florence, A. and Halbert, G. (2018) Microfactory – Blend – Compression - Performance test. In: CMAC Annual Open Day, 2018-10-25 - 2018-10-26.

Halbert, Gavin and Dunn, Claire and Khadra, Ibrahim and Wilson, Clive (2018) Equilibrium solubility in simulated intestinal media. In: "5 Years of progress in Oral Biopharmaceutics - IMI OrBiTo project and global biopharmaceutics research", 2018-09-17 - 2018-09-18, AstraZeneca, Granta Park.

Halbert, Gavin (2018) Novel formulation and biopharmaceutical challenges of oral cancer therapy. In: 78th FIP world Congress of Pharmacy and Pharmaceutical Sciences, 2018-09-02 - 2018-09-06, Scottish Event Campus.

Halbert, Gavin (2018) Drug to patient : pharmaceutical and scientific collaboration. In: 78th FIP world Congress of Pharmacy and Pharmaceutical Sciences, 2018-09-02 - 2018-09-06, Scottish Event Campus.

Brown, Cameron J. and McGlone, Thomas and Yerdelen, Stephanie and Srirambhatla, Vijay and Mabbott, Fraser and Gurung, Rajesh and Briuglia, Maria L. and Ahmed, Bilal and Polyzois, Hector and McGinty, John and Perciballi, Francesca and Fysikopoulos, Dimitris and Macfhionnghaile, Pól and Siddique, Humera and Raval, Vishal and Harrington, Tomás S. and Vassileiou, Antony D. and Robertson, Murray and Prasad, Elke and Johnston, Andrea and Johnston, Blair and Nordon, Alison and Srai, Jagjit S. and Halbert, Gavin and ter Horst, Joop H. and Price, Chris J. and Rielly, Chris D. and Sefcik, Jan and Florence, Alastair J. (2018) Enabling precision manufacturing of active pharmaceutical ingredients : workflow for seeded cooling continuous crystallisations. Molecular Systems Design & Engineering, 2018 (3). pp. 518-549. ISSN 2058-9689

Wood, Sarahjane and Halbert, Gavin and Florence, Alastair (2018) Injection moulding- A novel method of solid oral dosage form manufacturing. In: Sci Formulation Forum, 2018-01-17 - 2018-01-18.

Turner, Alice J. and Halbert, Gavin W. and Florence, Alastair J. (2018) Inkjet printing of oral dosage forms to solubilize BCS Class II drugs. In: Sci Formulation Forum, 2018-01-17 - 2018-01-18.

Perrier, Jeremy and Zhou, Zhou and Dunn, Claire and Khadra, Ibrahim and Wilson, Clive G. and Halbert, Gavin (2018) Statistical investigation of the full concentration range of fasted and fed simulated intestinal fluid on the equilibrium solubility of oral drugs. European Journal of Pharmaceutical Sciences, 111. pp. 247-256. ISSN 0928-0987

2017

Ainousah, Bayan E and Perrier, Jeremy and Dunn, Claire and Khadra, Ibrahim and Wilson, Clive G. and Halbert, Gavin W (2017) Dual level statistical investigation of equilibrium solubility in simulated fasted and fed intestinal fluid. Molecular Pharmaceutics, 14 (12). pp. 4170-4180. ISSN 1543-8384

Turner, A. and Halbert, G. and Florence, A. (2017) Inkjet printing scalable dosage forms capable of increasing the solubility of BCS Class II drugs. In: AAPS Annual Meeting and Exposition 2017, 2017-11-12 - 2017-11-15, San Diego Convention Center.

Prasad, Elke and Islam, Muhammad and Robertson, John and Halbert, Gavin (2017) Example use of screening and analytical tools for secondary processing. In: CMAC Tier1 Showcase, 2017-11-09 - 2017-11-09, University of Strathclyde, SIPBS, CMAC.

Wood, Sarahjane and Halbert, Gavin and Florence, Alastair (2017) Solid oral dosage form manufacturing using injection moulding. In: C-SOPS Fall 2017 Industry Meeting, 2017-10-16 - 2017-10-17, Busch Campus, Rutgers University.

Kreiner, Michaela and Elliott, Moira and Halbert, Gavin (2017) Automatic capsule filling of liquid particulate dispersions: Importance of API particle size and rheology - a case study. In: APS International Pharm Sci Conference 2017, 2017-09-05 - 2017-09-07, University of Hertfordshire,.

Zhou, Zhou and Dunn, Claire and Khadra, Ibrahim and Wilson, Clive G. and Halbert, Gavin W. (2017) Influence of physiological gastrointestinal surfactant ratio on the equilibrium solubility of BCS class II drugs investigated using a four component mixture design. Molecular Pharmaceutics. ISSN 1543-8384

Wood, Sarahjane and Halbert, Gavin (2017) 'Build a release' achieving polymer based disintegrating tablets. In: CMAC Summer School, 2017-06-12 - 2017-06-16.

Doerr, Frederik and Brammer, Elanor and Wood, Sarahjane and Halbert, Gavin and Florence, Alastair (2017) Morphological characterisation of solid pharmaceutical products using X-ray tomography. In: Bruker micro-CT User Meeting, 2017-06-12 - 2017-06-15.

Halbert, Gavin (2017) The pharmaceutical challenge of cancer research. University of Strathclyde, Glasgow. (Unpublished)

Wood, Sarahjane and Halbert, Gavin and Florence, Alastair (2017) Solid oral dosage form manufacturing using injection moulding. In: CMAC Annual Open Day 2017, 2017-03-23 - 2017-03-24, Technology and Innovation Centre, University of Strathclyde.

Mendez Torrecillas, Carlota and Halbert, Gavin W. and Lamprou, Dimitrios A. (2017) A novel methodology to study polymodal particle size distributions produced during continuous wet granulation. International Journal of Pharmaceutics, 519 (1-2). pp. 230-239. ISSN 0378-5173

Zhou, Zhou and Dunn, Claire and Khadra, Ibrahim and Wilson, Clive G. and Halbert, Gavin W. (2017) Statistical investigation of simulated fed intestinal media composition on the equilibrium solubility of oral drugs. European Journal of Pharmaceutical Sciences, 99. pp. 95-104. ISSN 0928-0987

2016

Wood, Sarahjane and Halbert, G. W. and Florence, A. (2016) Achieving immediate release dosage forms using DoE and injection moulding. In: First I2APM International Symposium, 2016-11-30 - 2016-12-01, University of Strathclyde.

Wilson, Clive G. and Halbert, Gavin W. and Mains, Jenifer (2016) The gut in the beaker : missing the surfactants. International Journal of Pharmaceutics, 514 (1). pp. 73-80. ISSN 0378-5173

Brammer, Elanor and Halbert, Gavin and Lamprou, Dimitrios (2016) An investigation into drug content uniformity in fused filament fabrication. In: 2016 AAPS Annual meeting and exposition, 2016-11-13 - 2016-11-17, Colorado Convention Center. (Unpublished)

Kourentas, Alexandros and Vertzoni, Maria and Khadra, Ibrahim and Symillides, Mira and Clark, Hugh and Halbert, Gavin and Butler, James and Reppas, Christos (2016) Evaluation of the impact of excipients and an albendazole salt on albendazole concentrations in upper small intestine using an in vitro biorelevant gastrointestinal transfer (BioGIT) system. Journal of Pharmaceutical Sciences, 105 (9). pp. 2896-2903. ISSN 0022-3549

Etherson, Kelly and Halbert, Gavin and Elliott, Moira (2016) The influence of non-ionisable excipients on precipitation parameters measured using the CheqSol method. Journal of Pharmacy and Pharmacology, 68 (9). pp. 1131-1142. ISSN 0022-3573

Kreiner, M. and Thayne, N. and Harkins, D. and Rae, K. and Halbert, G. W. (2016) Liquid-filled hard gelatin capsules : excipient/capsule compatibility studies. In: 7th APS International PharmSci Conference, 2016-09-05 - 2016-09-07, University of Strathclyde.

Wood, Sarahjane and Halbert, Gavin and Florence, Alastair (2016) Injection moulding : a novel approach to the manufacture of homogenous immediate release solid oral dosage forms. In: 7th APS International PharmSci Conference, 2016-09-05 - 2016-09-07, University of Strathclyde.

Turner, Alice J. and Halbert, Gavin W. and Florence, Alastair J. (2016) Inkjet printing oral dosage forms. In: 7th APS International PharmSci Conference, 2016-09-05 - 2016-09-07, University of Strathclyde.

Lord, N. and Ford, S.J. and Elliott, M. and Halbert, G.W. (2016) A quest to find the cause of unknown peaks in cleaning verification chromatography following the manufacture of pharmaceutical preparations. In: 7th APS International PharmSci Conference, 2016-09-05 - 2016-09-07, University of Strathclyde.

Osorio, Juan G. and Sayin, Ridade and Kalbag, Arjun V. and Litster, James D. and Martinez-Marcos, Laura and Lamprou, Dimitrios A. and Halbert, Gavin W. (2016) Scaling of continuous twin screw wet granulation. AIChE Journal. ISSN 0001-1541

Prasad, Elke and Halbert, Gavin H. (2016) Online UV imaging of API-excipient mixtures during dissolution. In: CMAC Internal Research Day, 2016-04-29, University of Strathclyde.

Martinez-Marcos, Laura and Lamprou, Dimitrios and Halbert, Gavin (2016) Hot-melt extrusion (HME) formulations of Albendazole for increasing dissolution properties. In: PBP 10th World Meeting in Pharmaceutics, Biopharmeceutics and Pharmaceutical Technology, 2016-04-04 - 2016-04-07, SECC.

Elliott, Moira A. and Halbert, Gavin W. (2016) Manometric Temperature Measurement (MTM) lyophilisation of a challenging clinical trial pharmaceutical. In: PBP 10th World Meeting in Pharmaceutics, Biopharmeceutics and Pharmaceutical Technology, 2016-04-04 - 2016-04-07, SECC. (Unpublished)

Brammer, Elanor M. and Halbert, Gavin W. and Lamprou, Dimitrios A. (2016) An investigation into fused filament fabrication for pharmaceutical manufacturing. In: PBP 10th World Meeting in Pharmaceutics, Biopharmeceutics and Pharmaceutical Technology, 2016-04-04 - 2016-04-07, SECC. (Unpublished)

Westwood, N. and Londesbrough, D. and Ford, S. J. and Halbert, G. W. (2016) Explosivity : an unusual challenge in drug development. In: 10th World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology, 2016-04-04 - 2016-04-07, SECC.

Martinez Marcos, Laura and Lamprou, Dimitrios and McBurney, Roy and Halbert, Gavin (2016) A novel hot-melt extrusion formulation of albendazole for increasing dissolution properties. International Journal of Pharmaceutics, 499 (1-2). pp. 175-185. ISSN 0378-5173

2015

Bowornsaksit, C. and Lamprou, D. and Halbert, G. and Prasad, E. (2015) Preparation and characterisation of free flowing solid lipid based drug delivery systems using a twin screw extruder. In: CMAC Internal Research Day, 2015-09-25.

Sayin, Ridade and Martinez Marcos, Laura and Osorio, Juan G. and Cruise, Paul and Jones, Ian and Halbert, Gavin W. and Lamprou, Dimitrios A. and Litster, James D. (2015) Investigation of an 11mm diameter twin screw granulator : screw element performance and in-line monitoring via image analysis. International Journal of Pharmaceutics. ISSN 0378-5173

2014

Mather, Stephen J. and Nock, Berthold A. and Maina, Theodosia and Gibson, Vickie and Ellison, David and Murray, Iain and Sobnack, Ravin and Colebrook, Steve and Wan, Susan and Halbert, Gavin and Szysko, Teresa and Powles, Thomas and Avril, Norbert (2014) GRP receptor imaging of prostate cancer using [(99m)Tc]Demobesin 4 : a first-in-man study. Molecular Imaging and Biology, 16 (6). pp. 888-895. ISSN 1860-2002

Kourentas, A and Vertzoni, M and Khadra, Ibrahim and Halbert, Gavin and Clark, Hugh and Butler, James and Reppas, Christos (2014) Albendazole vs. albendazole sulphate in the fasted upper gastrointestinal lumen based on ex vivo and in vitro data. In: American Association of Pharmaceutical Scientists, 2014-11-02 - 2014-11-06, San Diego.

Armstrong, M. and Kreiner, M. and Elliott, M.A. and Halbert, G.W. (2014) Comparative analysis of the physical and chemical properties of new and expired blister pack foils for hard gelatin capsule packaging. In: APS PharmSci 2014, 2014-09-08 - 2014-12-10, University of Hertfordshire.

Kreiner, M. and Armstrong, M. and Elliott, M.A. and Halbert, G.W. (2014) Rheology to guide formulation development of particulate dispersions for automated capsule filling. In: APS PharmSci 2014, 2014-09-08 - 2014-12-10, University of Hertfordshire.

Bergström, Christel A.S. and Holm, René and Jørgensen, Søren Astrup and Andersson, Sara B.E. and Artursson, Per and Beato, Stefania and Borde, Anders and Box, Karl and Brewster, Marcus and Dressman, Jennifer and Feng, Kung-I. and Halbert, Gavin and Kostewicz, Edmund and McAllister, Mark and Muenster, Uwe and Thinnes, Julian and Taylor, Robert and Mullertz, Anette (2014) Early pharmaceutical profiling to predict oral drug absorption : current status and unmet needs. European Journal of Pharmaceutical Sciences, 57. pp. 173-199. ISSN 0928-0987

Etherson, Kelly and Halbert, Gavin and Elliott, Moira (2014) Determination of excipient based solubility increases using the CheqSol method. International Journal of Pharmaceutics, 465 (1-2). pp. 202-209. ISSN 0378-5173

Yip, Kent and Goh, Vicky and Gregory, Jane and Simcock, Ian and Stirling, J. James and Taylor, N. Jane and Kozarski, Robert and Mitchell, Andrew and Bosopem, Sam and Halbert, Gavin and Alonzi, Roberto and Miles, David and Hoskin, Peter (2014) The acute physiological effects of the vaso-active drug, L-NNA, a nitric oxide synthase inhibitor, on renal and tumour perfusion in human subjects. Journal of Cancer Therapy, 5 (1). pp. 44-52. 05. ISSN 2151-1942

2013

Horsley, Laura and Cummings, Jeff and Middleton, Mark and Ward, Tim and Backen, Alison and Clamp, Andrew and Dawson, Martin and Farmer, Hayley and Fisher, Nita and Halbert, Gavin and Halford, Sarah and Harris, Adrian and Hasan, Jurjees and Hogg, Philip and Kumaran, Gireesh and Little, Ross and Parker, Geoff J. M. and Potter, Paula and Saunders, Mark and Roberts, Caleb and Shaw, Danielle and Smith, Nigel and Smythe, Jon and Taylor, Andrew and Turner, Helen and Watson, Yvonne and Dive, Caroline and Jayson, Gordon C., Cancer Research UK Drug Development Office Phase I clinical trial (2013) A phase 1 trial of intravenous 4-(N-(S-glutathionylacetyl)amino) phenylarsenoxide (GSAO) in patients with advanced solid tumours. Cancer Chemotherapy and Pharmacology, 72 (6). pp. 1343-1352. ISSN 1432-0843

Dick, Lindsay J and Gray, Andrew and Ram, Asha and Hume, Aileen and Parris, Caroline and Hogg, Philip J and Elliott, Moira A and Ford, Steven J and Halbert, Gavin W (2013) Elimination of the antimicrobial action of the organoarsenical cancer therapeutic, 4-(N-(S-glutathionylacetyl)amino) phenylarsonous acid, before finished product sterility testing. Journal of Pharmacy and Pharmacology, 65 (11). 1664–1669.

Prasad, Elke and Halbert, Gavin and Elliott, Moira (2013) Characterisation of a liquid-capsule-fill-formulation performance on an automated capsule filling machine (CFS1000). In: APS PharmSci 2013, 2013-09-02 - 2013-09-04, Heriot Watt University.

Armstrong, Michelle and Kreiner, Michaela and Elliott, Moira and Halbert, Gavin (2013) Rheological characterisation of formulations for liquid fill hard gelatin capsules. In: APS PharmSci 2013, 2013-09-02 - 2013-09-04, Heriot Watt University.

Halbert, Gavin and Elliott, Moira and Ford, Steven and Dick, Lindsay and Schmidt, Elke (2013) Improved pharmaceutical stability of a boronphenylalanine mannitol formulation for boron neutron capture therapy. European Journal of Pharmaceutical Sciences, 48. pp. 735-739. ISSN 0928-0987

2012

Gray, Andrew and Dick, Lindsay and Elliott, Moira and Ford, Steven and Halbert, Gavin (2012) A comparative analysis of two different analysers used for determination of the Total Organic Carbon in pharmaceutical grade water. European Journal of Parenteral and Pharmaceutical Sciences, 17 (2). pp. 47-51. ISSN 0964-4679

Jorgensen, Heather and Cosimo, Emilio and Elliott, Moira and Michie, Alison and Holyoake, Tessa and Halbert, Gavin and McCaig, Alison (2012) Targeting proliferating CLL cells with a novel synthetic low density lipoprotein drug delivery system. Haematologica, 97 (supple). p. 54. 0141. ISSN 0390-6078

Schmidt, Elke and Dooley, Neil and Ford, Steven J. and Elliott, Moira and Halbert, Gavin W. (2012) Physicochemical investigation of the influence of saccharide-based parenteral formulation excipients on l-p-boronphenylalanine solubilisation for boron neutron capture therapy. Journal of Pharmaceutical Sciences, 101 (1). pp. 223-232. ISSN 0022-3549

Gray, Andrew and Dick, Lindsay and Elliott, Moira and Ford, Steven and Halbert, Gavin (2012) Comparative analysis of TOC and conductivity analysers as applied to pharmaceutical water analysis. In: UK Pharm Sci 2012, 2012-09-12 - 2012-09-14.

2011

Dick, Lindsay and Dooley, Neil and Elliott, Moira A and Ford, Steven J and Gordon, Malcolm R and Halbert, Gavin W and Kerr, William J (2011) Boron phenylalanine and related impurities: HPLC analysis, stability profile and degradation pathways. Journal of Pharmaceutical and Biomedical Analysis, 56 (3). pp. 633-636.

Kreiner, M. and Ford, S. and Elliott, M. and Halbert, G. W. (2011) Tuning the reconstitution conditions improves stability and handling of ZD2767P in an aqueous environment. In: APS PharmSci Conference 2011, 2011-08-30 - 2011-09-02.

Danson, S. J. and Johnson, P. and Ward, T. H. and Dawson, M. and Denneny, O. and Dickinson, G. and Aarons, L. and Watson, A. and Jowle, D. and Cummings, J. and Robson, L. and Halbert, Gavin and Dive, C. and Ranson, M. (2011) Phase I pharmacokinetic and pharmacodynamic study of the bioreductive drug RH1. Annals of Oncology, 22 (7). pp. 1653-1660. ISSN 1569-8041

Green, S. and Phoenix, B. and Mill, A. J. and Hill, M. and Charles, M. W. and Thompson, J. and Jones, B. and Ngoga, D. and Detta, A. and James, N. D. and Doran, J. and Graham, N. and Ghani, Z. and Wojnecki, C. and Halbert, G. and Elliott, M. and Ford, S. and Sheehan, T. M. T. and Vickerman, J. and Lockyer, N. and Croswell, G. and Boddy, A. and King, A. and Cruickshank, G. S. (2011) The Birmingham Boron Neutron Capture Therapy (BNCT) project : developments towards selective internal particle therapy. Clinical Oncology, 23 (3). S23-S24. ISSN 0936-6555

2010

Zhou, Peixun and Hatziieremia, Sophia and Elliott, Moira A and Scobie, Linda and Crossan, Claire and Michie, Alison M and Holyoake, Tessa L and Halbert, Gavin W and Jørgensen, Heather G (2010) Uptake of synthetic low density Lipoprotein by leukemic stem cells--a potential stem cell targeted drug delivery strategy. Journal of Controlled Release, 148 (3). pp. 380-387.

Schmidt, E. and Ford, S. and Dooley, N. and Elliot, M. and Halbert, G. (2010) Effects of substituting Fructose by Mannitol in a pharmaceutical formulation. Journal of Pharmacy and Pharmacology, 62 (10). pp. 1428-1429. ISSN 0022-3573

Elliott, M. A. and Schmidt, Elke and Ford, S. J. and Halbert, G. W. (2010) Experiences of melt fill production of Fenretinide/Lym-X-Sorb (TM) hard gelatin capsules for Phase I clinical trial. In: UNSPECIFIED.

Dooley, N. and Ford, S. J. and Prasad, Elke and Elliott, M. and Halbert, Gavin (2010) Experimental scrutiny and project timelines : an example. Journal of Pharmacy and Pharmacology, 62 (10). pp. 1208-1209. ISSN 0022-3573

Elliott, M.A. and Prasad, E. and Ford, S.J. and Halbert, G.W. (2010) Experiences of melt fi ll production of Fenretinide/Lym-X-Sorb™ hard gelatin capsules for Phase I clinical trial. In: UK-PharmSci 2010 – The Science of Medicines, 2010-09-01 - 2010-09-03.

Ngoga, D. G. and Cruickshank, G. and Detta, A. and Green, S. and James, N. D. and Wojnecki, C. and Doran, J. and Graham, N. and Ghani, Z. and Halbert, G. and Elliot, M. and Ford, S. and Braithwaite, R. and Sheehan, T. M. T. and Vickerman, J. and Lockyer, N. and Croswell, G. and Sugar, R. and Boddy, A. (2010) Boron Neutron Capture Therapy (BNCT) : clinical optimization of uptake parameters of Boronophenylalanine (BPA). Neuro-Oncology, 12 (3). p. 62. P.164. ISSN 1522-8517

2009

Cruickshank, G.S. and Ngoga, D. and Detta, A. and Green, S. and James, N.D. and Wojnecki, C. and Doran, J. and Halbert, G.W. (2009) A Cancer Research UK pharmacokinetic study of bpa-mannitol in patients with high grade glioma to optimise uptake parameters for clinical trials of BNCT. Applied Radiation and Isotopes, 67 (7-8). S31-S33. ISSN 0969-8043

Lee, C.P. and Payne, G.S. and Oregioni, A, and Ruddle, R. and Tan, S. and Raynaud, F.I. and Eaton, D. and Campbell, M.J. and Cross, K. and Halbert, G.W. and Tracy, M. and McNamara, J. and Seddon, B. and Leach, M.O. and Workman, P. and Judson, I. (2009) A phase I study of the nitroimidazole hypoxia marker SR4554 using 19F magnetic resonance spectroscopy. British Journal of Cancer, 101. pp. 1860-1868. ISSN 1532-1827

Halbert, G.W. (2009) The weakest link is getting stronger. European Pharmaceutical Review, 14 (6). pp. 68-72. ISSN 1360-8606

2008

Elliott, Moira and Halbert, G.W. (2008) Maintaining a frozen shipping environment for Phase I clinical trial distribution. International Journal of Pharmaceutics, 346 (1-2). pp. 89-92. ISSN 0378-5173

2007

Steward, W. P. and Middleton, M. and Benghiat, A. and Loadman, P. M. and Hayward, C. and Waller, S. and Ford, S. and Halbert, G. and Patterson, L. H. and Talbot, D. (2007) The use of pharmacokinetic and pharmacodynamic end points to determine the dose of AQ4N, a novel hypoxic cell cytotoxin, given with fractionated radiotherapy in a phase I study. Annals of Oncology, 18 (6). pp. 1098-1103. ISSN 1569-8041

2006

Ranson, Malcolm and Middleton, Mark, R. and Bridgewater, John and Lee, Siow Ming and Dawson, M. and Jowle, Debra and Halbert, G.W. and Waller, Sue and McGrath, Helen and Gumbrell, Lindsey and McElhinney, R. Stanley and Donnelly, Dorothy and McMurry, T. Brian H. and Margison, Geoffrey, P. (2006) Lomeguatrib, a potent inhibitor of o-6-alkylguanine-DNA-alkyltrasnferase: phase i safety, pharmacodynamic, and pharmacokinetic trial and evaluation in combination with temozolomide in patients with advanced solid tumours. Clinical Cancer Research, 12 (5). pp. 1577-1584. ISSN 1557-3265

2005

Elliott, M A and Halbert, G W (2005) Maintaining the cold chain shipping environment for Phase I clinical trial distribution. International Journal of Pharmaceutics, 299 (1-2). pp. 49-54. ISSN 0378-5173

Hayavi, S. and Halbert, G.W. (2005) Synthetic low density lipoprotein, a novel biomimetic LiPID supplement for serum free tissue culture. Biotechnology Progress, 21 (4). pp. 1262-1268. ISSN 8756-7938

2004

Elliott, M. A. and Halbert, G. W. (2004) Verification of a phase I clinical trial distribution network for cold storage materials. [Review]

O'Donnell, A. and Judson, I. and Dowsett, M. and Raynaud, F. and Dearnaley, D. and Mason, M. and Harland, S. and Robbins, A. and Halbert, G.W. and Nutley, B. and Jarman, M. (2004) Hormonal impact of the 17 alpha-hydroxylase/C-17,C-20-lyase inhibitor abiraterone acetate (CB7630) in patients with prostate cancer. British Journal of Cancer, 90 (12). pp. 2317-2325. ISSN 1532-1827

2003

Ford, S J and Elliott, M A and Halbert, G W (2003) Use of mathematical derivatives (time-domain differentiation) on chromatographic data to enhance the detection and quantification of an unknown 'rider' peak. Journal of Pharmaceutical and Biomedical Analysis, 33 (4). pp. 563-570. ISSN 0731-7085

Seddon, B.M. and Payne, G.S. and Simmons, L. and Ruddle, R. and Grimshaw, R. and Tan, S. and Turner, A. and Raynaud, F. and Halbert, G.W. and Leach, M.O. and Judson, I. and Workman, P. (2003) A phase I study of SR-4554 via intravenous administration for noninvasive investigation of tumor hypoxia by magnetic resonance spectroscopy in patients with malignancy. Clinical Cancer Research, 9 (14). pp. 5101-12. ISSN 1557-3265

2002

Elliott, M A and Ford, S J and Walker, A A and Hargreaves, R H J and Halbert, G W (2002) Development of a lyophilised RH1 formulation : a novel DT diaphorase activated alkylating agent. Journal of Pharmacy and Pharmacology, 54 (4). pp. 487-492. ISSN 0022-3573

Baillie, G. and Owens, M. and Halbert, G.W. (2002) A synthetic low density lipoprotein particle capable of supporting U937 proliferation in vitro. Journal of Lipid Research, 43. pp. 69-73. ISSN 0022-2275

This list was generated on Tue Mar 19 02:33:52 2024 GMT.