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Number of items: 114.

2024

Zorzatto, Renan and Mulrainey, Paul T. and Reid, Marc and Tuttle, Tell and Lindsay, David M. and Kerr, William J. (2024) C–H activation and hydrogen isotope exchange of aryl carbamates using iridium(I) complexes bearing chelating NHC-phosphine ligands. Chemistry - A European Journal, 30 (69). e202403090. ISSN 1521-3765

Paterson, Laura C. and Humphreys, Philip G. and Kelly, Henry A. and Kerr, William J. (2024) Collaborative GSK-University of Strathclyde doctoral research and training programmes : transforming approaches to industry-academia engagement. Drug Discovery Today, 29 (11). 104162. ISSN 1359-6446

Smith, Blair I. P. and Knight, Nathan M. L. and Knox, Gary J. and Lindsay, David M. and Paterson, Laura C. and Bergare, Jonas and Elmore, Charles S. and Bragg, Ryan A. and Kerr, William J. (2024) Selective deuteration and tritiation of pharmaceutically relevant sulfoximines. Angewandte Chemie International Edition. e202417179. ISSN 1521-3773

Knight, Nathan M. L. and Thompson, James D. F. and Parkinson, John A. and Lindsay, David and Tuttle, Tell and Kerr, William J. (2024) Iridium-catalysed C(sp3)−H activation and hydrogen isotope exchange via nitrogen-based carbonyl directing groups. Advanced Synthesis and Catalysis, 366 (11). pp. 2577-2586. ISSN 1615-4150

Fleetwood, Thomas D. and Kerr, William J. and Mason, Joseph (2024) Copper-mediated N-Trifluoromethylation of O-Benzoylhydroxylamines. Chemistry - A European Journal, 30 (6). e202303314. ISSN 1521-3765

2023

Bradley, Erin and Fusani, Lucia and Chung, Chun-wa and Craggs, Peter D. and Demont, Emmanuel H. and Humphreys, Philip G. and Mitchell, Darren J. and Phillipou, Alexander and Rioja, Inmaculada and Shah, Rishi R. and Wellaway, Christopher R. and Prinjha, Rab K. and Palmer, David S. and Kerr, William J. and Reid, Marc and Wall, Ian D. and Cookson, Rosa (2023) Structure-guided design of a domain-selective bromodomain and extra terminal N-terminal bromodomain chemical probe. Journal of Medicinal Chemistry, 66 (23). pp. 15728-15749. ISSN 0022-2623

Davenport, Elliot and Negru, Daniela E. and Badman, Geoff and Lindsay, David M. and Kerr, William J. (2023) Robust and general late-stage methylation of aryl chlorides : application to isotopic labeling of drug-like scaffolds. ACS Catalysis, 13 (17). pp. 11541-11547. ISSN 2155-5435

Hall, Callum G. J. and Sneddon, Helen F. and Pogány, Peter and Lindsay, David M. and Kerr, William J. (2023) Experimental and computational insights into the mechanism of the copper(I)-catalysed sulfonylative Suzuki-Miyaura reaction. Chemical Science, 14 (24). pp. 6738-6755. ISSN 2041-6539

Williams, Jason D. and Leach, Stuart G. and Kerr, William J. (2023) An umpolung approach to acyclic 1,4-dicarbonyl amides via photoredox-generated carbamoyl radicals. Chemistry - A European Journal, 29 (28). e202300403. ISSN 1521-3765

Owens, Philippa and Smith, Blair and Lindsay, David and Campos, Sebastien and Kerr, William J (2023) Selective deuteration of heterocycle N-oxides via iridium-catalyzed hydrogen isotope exchange. Synthesis, 55 (21). pp. 3644-3651. ISSN 0039-7881

2022

Shaw, Paul and Hassell-Hart, Storm J. and Douglas, Gayle E. and Malcolm, Andrew G. and Kennedy, Alan R. and White, Gemma V. and Paterson, Laura C. and Kerr, William J. (2022) Oxygenated cyclopentenones via the pauson-khand reaction of silyl enol ether substrates. Organic Letters, 24 (14). pp. 2750-2755. ISSN 1523-7060

2021

Timofeeva, Daria S. and Lindsay, David M. and Kerr, William J. and Nelson, David J. (2021) Are rate and selectivity correlated in iridium-catalysed hydrogen isotope exchange reactions? Catalysis Science and Technology, 11 (16). pp. 5498-5504. ISSN 2044-4753

Kerr, William J. and Knox, Gary J. and Reid, Marc and Tuttle, Tell (2021) Catalyst design in C–H activation : a case study in the use of binding free energies to rationalise intramolecular directing group selectivity in iridium catalysis. Chemical Science, 12 (19). pp. 6747-6755. ISSN 2041-6539

Cochrane, Alison R. and Kerr, William J. and Paterson, Laura C. and Pearson, Colin M. and Shaw, Paul (2021) Advances in the cobalt-catalysed Pauson-Khand reaction : development of a sulfide-promoted, microwave-assisted protocol. Tetrahedron, 78. 131805. ISSN 0040-4020

Baker, Blake J. M. and Kerr, William J. and Lindsay, David M. and Patel, Vipulkumar K. and Poole, Darren L. (2021) A sustainable and scalable multicomponent continuous flow process to access fused imidazoheterocycle pharmacophores. Green Chemistry, 23 (1). pp. 280-287. ISSN 1463-9262

2020

Timofeeva, Daria S. and Lindsay, David M. and Kerr, William J. and Nelson, David J. (2020) A quantitative empirical directing group scale for selectivity in iridium-catalysed hydrogen isotope exchange reactions. Catalysis Science and Technology, 10 (21). pp. 7249-7255. ISSN 2044-4753

Simionesie, Dorin and O’Callaghan, Greg and Costa, Joao L.L.F.S. and Giusti, Leonardo and Kerr, William J. and Sefcik, Jan and Mulheran, Paul A. and Zhang, Zhenyu J. (2020) Clustering behaviour of polyaromatic compounds mimicking natural asphaltenes. Colloids and Surfaces A: Physicochemical and Engineering Aspects, 603. 125221. ISSN 0927-7757

Kerr, William J. and Knox, Gary J. and Reid, Marc and Tuttle, Tell and Bergare, Jonas and Bragg, Ryan A. (2020) Computationally-guided development of a chelated NHC-P iridium(I) complex for the directed hydrogen isotope exchange of aryl sulfones. ACS Catalysis, 10 (19). pp. 11120-11126. ISSN 2155-5435

Wellaway, Christopher R. and Bamborough, Paul and Bernard, Sharon G. and Chung, Chun-wa and Craggs, Peter D. and Cutler, Leanne and Demont, Emmanuel H. and Evans, John P. and Gordon, Laurie and Karamshi, Bhumika and Lewis, Antonia J. and Lindon, Matthew J. and Mitchell, Darren J. and Rioja, Inmaculada and Soden, Peter E. and Taylor, Simon and Watson, Robert J. and Willis, Rob and Woolven, James M. and Wyspiańska, Beata S. and Kerr, William J. and Prinjha, Rab K. (2020) Structure-based design of a bromodomain and extraterminal domain (BET) inhibitor selective for the N-terminal bromodomains that retains an anti-inflammatory and antiproliferative phenotype. Journal of Medicinal Chemistry, 63 (17). pp. 9020-9044. ISSN 0022-2623

Timofeeva, Daria S. and Lindsay, David M. and Kerr, William J. and Nelson, David J. (2020) Quantitative prediction of selectivity in iridium-catalysed hydrogen isotope exchange reactions. ChemRxiv, [London].

Kerr, William and Paterson, Laura and Knox, Gary (2020) Recent advances in iridium(I) catalysis towards directed hydrogen isotope exchange. Journal of Labelled Compounds and Radiopharmaceuticals, 63 (6). pp. 281-295. ISSN 0362-4803

Queen, Adele E. and Hesk, David and Lindsay, David M. and Kerr, William J. and Rehder, Kenneth and Fennell, Tim and Mascarella, Wayne and Zhong, Desong and Runyon, Scott (2020) Synthesis of [3H] and [14C]genipin. Journal of Labelled Compounds and Radiopharmaceuticals, 63 (4). pp. 196-202. ISSN 0362-4803

Lindsay, David M. and Kerr, William J.; Hapke, Marko and Hilt, Gerhard, eds. (2020) Recent advances in the Pauson-Khand reaction. In: Cobalt Catalysis in Organic Synthesis. Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim, Germany, pp. 259-286. ISBN 9783527814855

Cochrane, Alison R. and Kennedy, Alan R. and Kerr, William J. and Lindsay, David and Reid, Marc and Tuttle, Tell (2020) The natural product lepidiline A as an N-heterocyclic carbene ligand precursor in complexes of the type [Ir(cod)(NHC)PPh3)]X : synthesis, characterisation, and application in hydrogen isotope exchange catalysis. Catalysts, 10 (2). 161. ISSN 2073-4344

2019

Barrett, Tim N. and Taylor, Jonathan A. and Barker, Daniel and Procopiou, Panayiotis A. and Thompson, James D. F. and Barrett, John and Le, Joelle and Lynn, Sean M. and Pogany, Peter and Pratley, Cassie and Pritchard, John M. and Roper, James A. and Rowedder, James E. and Slack, Robert J. and Vitulli, Giovanni and Macdonald, Simon J. F. and Kerr, William J. (2019) Profile of a highly selective quaternized pyrrolidine betaine αvβ6 integrin inhibitor - (3S)-3-(3-(3,5-Dimethyl-1H-pyrazol-1-yl)phenyl)-4-((1S and 1R,3R)-1-methyl-3-(2- (5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)ethyl)pyrrolidin-1-ium-1-yl)butanoate synthesized by stereoselective methylation. Journal of Medicinal Chemistry, 62 (16). pp. 7543-7556. ISSN 0022-2623

Tinworth, Christopher P. and Lithgow, Hannah and Dittus, Lars and Bassi, Zuni I. and Hughes, Sophie E. and Muelbaier, Marcel and Dai, Han and Smith, Ian E. D. and Kerr, William J. and Burley, Glenn A. and Bantscheff, Marcus and Harling, John D. (2019) PROTAC-mediated degradation of Bruton's tyrosine kinase is inhibited by covalent binding. ACS Chemical Biology, 14 (3). pp. 342-347. ISSN 1554-8937

2018

Kerr, William J. and Mudd, Richard J. and Reid, Marc and Atzrodt, Jens and Derdau, Volker (2018) Iridium-catalyzed Csp3-H activation for mild and selective hydrogen isotope exchange. ACS Catalysis, 8 (11). 10895–10900. ISSN 2155-5435

Bonfield, Holly E. and Williams, Jason D. and Ooi, Wei Xiang and Leach, Stuart G. and Kerr, William J. and Edwards, Lee J. (2018) A detailed study of irradiation requirements towards an efficient photochemical Wohl‐Ziegler procedure in flow. ChemPhotoChem, 2 (10). pp. 938-944. ISSN 2367-0932

Kerr, William J. and McLaughlin, Mark and Paterson, Laura C. and Pearson, Colin M. (2018) Total synthesis 2-epi-alpha-cedren-3-one via a cobalt-catalysed Pauson-Khand reaction. Tetrahedron, 74 (38). pp. 5062-5068. ISSN 0040-4020

McGarry, David H. and Cooper, Ian R. and Walker, Rolf and Warrilow, Catherine E. and Pichowicz, Mark and Ratcliffe, Andrew J. and Salisbury, Anne-Marie and Savage, Victoria J. and Moyo, Emmanuel and Maclean, John and Smith, Andrew and Charrier, Cédric and Stokes, Neil R. and Lindsay, David M. and Kerr, William J. (2018) Design, synthesis and antibacterial properties of pyrimido[4,5-b]indol-8-amine inhibitors of DNA gyrase. Bioorganic and Medicinal Chemistry Letters, 28 (17). pp. 2998-3003. ISSN 0960-894X

Williams, Jason D. and Kerr, William J. and Leach, Stuart G. and Lindsay, David M. (2018) A practical and general amidation method from isocyanates enabled by flow technology. Angewandte Chemie International Edition, 57 (37). pp. 12126-12130. ISSN 1521-3773

Atzrodt, Jens and Derdau, Volker and Kerr, William and Reid, Marc (2018) C− H functionalisation for hydrogen isotope exchange. Angewandte Chemie International Edition, 57 (12). pp. 3022-3047. ISSN 1521-3773

Atzrodt, Jens and Derdau, Volker and Kerr, William and Reid, Marc (2018) Deuterium‐and tritium‐labelled compounds : applications in the life sciences. Angewandte Chemie International Edition, 57 (7). pp. 1758-1784. ISSN 1521-3773

2017

Kerr, William J. and Lindsay, David M. and Owens, Philippa K. and Reid, Marc and Tuttle, Tell and Campos, Sébastien (2017) Site-selective deuteration of N-heterocycles via iridium-catalyzed hydrogen isotope exchange. ACS Catalysis, 7 (10). 7182–7186. ISSN 2155-5435

Kerr, William J. and Reid, Marc and Tuttle, Tell (2017) Iridium-catalyzed formyl-selective deuteration of aldehydes. Angewandte Chemie International Edition, 56 (27). 7808–7812. ISSN 1521-3773

2016

Kerr, William J. and Mudd, Richard J. and Owens, Philippa K. and Reid, Marc and Brown, Jack A. and Campos, Sébastien (2016) Hydrogen isotope exchange with highly active iridium(I) NHC/phosphine complexes : a comparative counter-ion study. Journal of Labelled Compounds and Radiopharmaceuticals, 59 (14). pp. 601-603. ISSN 0362-4803

Kerr, William J. and Lindsay, David and Reid, Marc and Atzrodt, Jens and Derdau, Volker and Rojahn, Patrick and Weck, Remo (2016) Iridium-catalysed ortho-H/D and -H/T exchange under basic conditions : C-H activation of unprotected tetrazoles. Chemical Communications, 52 (40). pp. 6669-6672. ISSN 1359-7345

Kerr, William J. and Mudd, Richard J. and Brown, Jack A. (2016) Iridium(I) NHC/phosphine catalysts for mild and chemoselective hydrogenation processes. Chemistry - A European Journal, 22 (14). 4738–4742. ISSN 1521-3765

Kerr, William and Owens, Philippa Kate and Campos, Sébastien André (2016) Iridium-catalysed hydrogen isotope exchange for the selective deuteration of N-heterocycles. In: 44th Scottish Regional Meeting of The RSC Organic Division, 2016-01-13 - 2016-01-13, University of Aberdeen.

Kerr, William and Zorzatto De Morais, Renan (2016) Novel Iridium(I) complexes bearing chelating NHC/phosphine ligands : synthesis and application in challenging HIE processes. In: 44th Scottish Regional Meeting of The RSC Organic Division, 2016-01-13 - 2016-01-13, University of Aberdeen.

Kerr, William and Giusti, Leonardo and Brown, Jack (2016) Towards the total synthesis of Agariblazeispirol C. In: 44th Scottish Regional Meeting of The RSC Organic Division, 2016-01-13 - 2016-01-13, University of Aberdeen.

2015

Kerr, William and Owens, Philippa Kate and Campos, Sébastien André (2015) Iridium-catalysed hydrogen isotope exchange for the selective deuteration of N-heterocycles. In: 24th Annual Symposium of the International Isotope Society UK Group, 2015-11-06 - 2015-11-06, The Møller Centre, Churchill College, Cambridge.

Kerr, William and Paterson, Laura and Herbert, John and McNeill, Alan and Cross, Paul (2015) Isotopic labelling of functionalised arenes catalysed by Ir(I) species of the [(COD)Ir(NHC)(py)]PF6 complex class. Synlett, 27 (1). pp. 111-115. ISSN 0936-5214

Kerr, William J. and Lindsay, David M. and Patel, Vipulkumar K. and Rajamanickam, Muralikrishnan (2015) Efficient methods for enol phosphate synthesis using carbon-centred magnesium bases. Organic and Biomolecular Chemistry, 13 (40). pp. 10131-10135. ISSN 1477-0520

Kerr, William J. and Morrison, Angus J. and Paterson, Laura C. (2015) Synthesis of α-methylene propellanone via the strategic employment of metal-mediated cyclisation chemistry. Tetrahedron, 71 (33). 5356–5361. ISSN 0040-4020

Kerr, William and Zorzatto De Morais, Renan and Tuttle, Christopher (2015) Enhanced iridium(I) complexes bearing nhc-p chelating ligands : synthesis, activity and application in organic processes. In: ScotCHEM 2015, 2015-06-26 - 2015-06-26, University of Strathclyde.

Devlin, Jennifer and Kerr, William J. and Lindsay, David M. and McCabe, Timothy J.D. and Reid, Marc and Tuttle, Tell (2015) Iridium-catalysed ortho-directed deuterium labelling of aromatic esters – an experimental and theoretical study on directing group chemoselectivity. Molecules, 20 (7). pp. 11676-11698. ISSN 1420-3049

Atzrodt, Jens and Derdau, Volker and Kerr, William J. and Reid, Marc and Rojahn, Patrick and Weck, Remo (2015) Expanded applicability of iridum(I) NHC-phosphine catalysts in hydrogen isotope exchange processes with pharmaceutically-relevant heterocycles. Tetrahedron, 71 (13). pp. 1924-1929. ISSN 0040-4020

Kerr, William J. and Reid, Marc and Tuttle, Tell (2015) Iridium-catalyzed C-H activation and deuteration of primary sulfonamides : an experimental and computational study. ACS Catalysis, 5 (1). 402–410. ISSN 2155-5435

2014

Brown, Jack A. and Cochrane, Alison Ruth and Irvine, Stephanie and Kerr, William J. and Mondal, Bhaskar and Parkinson, John A. and Paterson, Laura C. and Reid, Marc and Tuttle, Tell and Andersson, Shalini and Nilsson, Göran N. (2014) Inside cover: The synthesis of highly active iridium(I) complexes and their application in catalytic hydrogen isotope exchange (Adv. Synth. Catal. 17/2014). Advanced Synthesis and Catalysis, 356 (17). p. 3474. ISSN 1615-4150

Brown, Jack A. and Cochrane, Alison R. and Irvine, Stephanie and Kerr, William J. and Mondal, Bhaskar and Parkinson, John A. and Paterson, Laura C. and Reid, Marc and Tuttle, Tell and Andersson, Shalini and Nilsson, Göran N. (2014) The synthesis of highly active iridium(I) complexes and their application in catalytic hydrogen isotope exchange. Advanced Synthesis and Catalysis, 356 (17). pp. 3551-3562. ISSN 1615-4150

Kerr, W.J. and Mudd, Richard J. and Paterson, Laura C. and Brown, John Alexander (2014) Iridium(I)-catalyzed regioselective C[BOND]H activation and hydrogen-isotope exchange of non-aromatic unsaturated functionality. Chemistry - A European Journal, 20 (45). pp. 14604-14607. ISSN 1521-3765

Carswell, Emma L. and Kerr, William J and McArthur, Duncan and Pazicky, Marek and Watson, Allan (2014) Development of chiral heteroleptic magnesium amides; asymmetric deprotonations mediated by six-membered metallocyclic amidomagnesium naphtholates. Tetrahedron, 70 (40). pp. 7344-7349. ISSN 0040-4020

Kerr, William J and Mudd, Richard J and Paterson, Laura and Brown, Jack (2014) Iridium(I)-catalyzed Regioselective C-H Activation and Hydrogen Isotope Exchange of Non-aromatic Unsaturated Functionality. Chemistry - A European Journal. ISSN 1521-3765

Kennedy, Alan R and Kerr, William and Moir, Rory and Reid, Marc (2014) Anion effects to deliver enhanced iridium catalysts for hydrogen isotope exchange processes. Organic and Biomolecular Chemistry, 12 (40). pp. 7927-7931. ISSN 1477-0520

Kerr, William and Rajamanickam, Muralikrishnan and Patel, Vipulkumar (2014) Chiral magnesium amides : efficient tools for the synthesis of enantioenriched enol phosphates. In: Challenges in Organic Chemistry (ISACS 14), 2014-08-07 - 2014-08-10, Shanghai Institute of Organic Chemistry.

Kerr, William and Reid, Marc and Tuttle, Christopher (2014) Design and application of iridium catalysts in hydrogen isotope exchange. In: XXVI International Conference on Organometallic Chemistry, 2014-07-13 - 2014-07-18, Royton Hotel, Sapporo.

Kerr, William and Mudd, Richard J. (2014) Highly active iridium(I) complexes for novel beta-selective hydrogen isotope exchange processes. Journal of Labelled Compounds and Radiopharmaceuticals, 57 (3). pp. 185-186. ISSN 0362-4803

Kerr, William and Reid, Marc and Tuttle, Christopher (2014) Iridium-catalysed ortho-deuteration of primary sulfonamides : an experimental and computational study. Journal of Labelled Compounds and Radiopharmaceuticals, 57 (3). pp. 183-184. ISSN 0362-4803

Cochrane, A R and Idziak, C and Kerr, William and Mondal, Bhaskar and Paterson, Laura C and Tuttle, Tell and Andersson, S. and Nilsson, G.N. (2014) Practically convenient and industrially-aligned methods for iridium-catalysed hydrogen isotope exchange processes. Organic and Biomolecular Chemistry, 12 (22). pp. 3598-3603. ISSN 1477-0520

2013

Bogacki, Rachael and Gill, Duncan M. and Kerr, W. J. and Lamont, Scott and Parkinson, John A. and Paterson, Laura C. (2013) Flexible access to conformationally-locked bicyclic morpholines. Journal of the Chemical Society, Chemical Communications, 49 (79). pp. 8931-8933. ISSN 0022-4936

Nic Daeid, Niamh and Jayaram, Saravana Kumar and Kerr, William (2013) Elemental profiling using ICPMS of methylamphetamine hydrochloride prepared from proprietary medication using the Moscow and hypophosphorous synthesis. Science and Justice, 53 (3). pp. 278-285. ISSN 1355-0306

Cochrane, Alison Ruth and Kerr, William and Sandell, Johan (2013) Preparation of [3H]fluoroethyl tosylate and its use in the labelling of the dopamine transporter radioligand [3H]FE-PE2I. Journal of Labelled Compounds and Radiopharmaceuticals, 56 (9-10). pp. 447-450. ISSN 0362-4803

Cochrane, Alison R and Irvine, Stephanie and Kerr, William J and Reid, Marc and Andersson, Shalini and Nilsson, Goran N (2013) Application of neutral iridium(I) N-heterocyclic carbene complexes in ortho-directed hydrogen isotope exchange. Journal of Labelled Compounds and Radiopharmaceuticals, 56 (9-10). pp. 451-454. ISSN 0362-4803

Kerr, William and Reid, Marc (2013) Emerging iridium complexes for further applications in hydrogen isotope exchange. In: SuBiCat I: Sustainable Catalytic Conversions of Renewable Substrates, 2013-03-24 - 2013-03-26, University of St Andrews.

Kerr, William and Mudd, Richard (2013) Highly active iridium(I) catalysts for mild hydrogenation processes. In: SuBiCat I: Sustainable Catalytic Conversions of Renewable Substrates, 2013-03-24 - 2013-03-26, University of St Andrews.

Nic Daeid, Niamh and Jayaram, Saravana Kumar and Kerr, W. J. and Meier-Augenstein, Wolfram and Kemp, Helen F. (2013) Influence of precursor solvent extraction on stable isotope signatures of methylamphetamine prepared from over-the-counter medicines using the Moscow and Hypophosphorous routes. Analytical and Bioanalytical Chemistry, 405 (9). 2931–2941. ISSN 1618-2642

Harling, John D and Deakin, Angela M and Campos, Sébastien and Grimley, Rachel and Chaudry, Laiq and Nye, Catherine and Polyakova, Oxana and Bessant, Christina M and Barton, Nick and Somers, Don and Barrett, John and Graves, Rebecca H and Hanns, Laura and Kerr, W. J. and Solari, Roberto (2013) Discovery of novel irreversible inhibitors of IL-2 inducible tyrosine kinase (Itk) by targeting cysteine 442 in the ATP pocket. Journal of Biological Chemistry (39). pp. 28195-28206. ISSN 1083-351X

Forsyth, Calum and Kerr, William J and Paterson, Laura (2013) Z-selective dimerization of aromatic terminal alkynes catalyzed by an iridium(I) n-heterocyclic carbene-phosphine system. Synlett, 24 (5). pp. 587-590. ISSN 0936-5214

2012

Kunalan, Vanitha and Kerr, William and Nic Daeid, Niamh (2012) Clarification of route specific impurities found in methylamphetamine synthesised using the Birch method. Forensic Science International, 223 (1-3). pp. 321-329. ISSN 0379-0738

Kerr, William and Cochrane, Alison Ruth and Andersson, Shalini and Nilsson, Goran N. and Sandell, Johan (2012) The application of highly active iridium(I) complexes in hydrogen isotope exchange, and the preparation of [3H]fluoroethyl tosylate for the tritiated labelling of radioligands. In: 11th International Symposium of the International Isotope Society, 2012-09-09 - 2012-09-13, University of Heidelberg.

Kerr, William and Goldie, Laura and Gill, Duncan M (2012) Efficient access to an array of optically-enriched oxabispidines and their use as chiral ligands in asymmetric synthesis. In: Challenges in Organic Chemistry and Chemical Biology (ISACS7), 2012-06-12 - 2012-06-15, University of Edinburgh.

Kerr, William and Monks, Natalie (2012) New asymmetric processes with emerging magnesium bisamide reagents. In: Challenges in Organic Chemistry and Chemical Biology (ISACS7), 2012-06-12 - 2012-06-15, University of Edinburgh.

Kerr, William and Forsyth, Calum (2012) Towards the total synthesis of Agariblazeispirol C. In: Challenges in Organic Chemistry and Chemical Biology (ISACS7), 2012-06-12 - 2012-06-15, University of Edinburgh.

Kunalan, Vanitha and Daeid, Niamh Nic and Kerr, William (2012) Investigation of the reaction impurities associated with methylamphetamine synthesized using the nagai method. Analytical Chemistry, 84 (13). pp. 5744-5752. ISSN 0003-2700

Kerr, William and Morrison, Angus J and Pazicky, Marek and Weber, Tina (2012) Modified Shapiro reactions with bismesitylmagnesium as an efficient base reagent. Organic Letters, 14 (9). pp. 2250-2253. ISSN 1523-7060

Kerr, William J.; Torres, Ramon Rios, ed. (2012) The Pauson-Khand Reaction : an introduction. In: The Pauson-Khand Reaction. John Wiley, Hoboken, pp. 1-21. ISBN 9780470970768

Brown, Jack A and Chudasama, Vijay and Giles, Melvyn E and Gill, Duncan M and Keegan, Philip S and Kerr, William J and Munday, Rachel H and Griffin, Karen and Watts, Andrew (2012) E- and Z-Stereoselectivity in the preparation of enamides from glycidyl sulfonamides and carbamates. Organic and Biomolecular Chemistry, 10 (3). pp. 509-511. ISSN 1477-0520

Brice, Heloise and Gill, Duncan M and Goldie, Laura and Keegan, Philip S and Kerr, William and Svensson, Per H (2012) Stereocontrolled access to optically-enriched oxabispidines. Chemical Communications, 48 (40). pp. 4836-4838. ISSN 1359-7345

2011

Kerr, William and Goldie, Laura and Gill, Duncan M (2011) Efficient access to an array of optically-enriched oxabispidines and their use as chiral ligands in asymmetric synthesis. In: 40th Scottish Regional Meeting of the Organic Division of the Royal Society of Chemistry, 2011-12-14 - 2011-12-14, University of Strathclyde.

Kerr, William and Gordon, Malcolm Roger and Harling, John D (2011) The development of Pauson-Khand Processes towards the rapid and unique synthesis of polycyclic sesquiterpene targets. In: 40th Scottish Regional Meeting of the Organic Division of the Royal Society of Chemistry, 2011-12-14 - 2011-12-14, University of Strathclyde.

Dick, Lindsay and Dooley, Neil and Elliott, Moira A and Ford, Steven J and Gordon, Malcolm R and Halbert, Gavin W and Kerr, William J (2011) Boron phenylalanine and related impurities: HPLC analysis, stability profile and degradation pathways. Journal of Pharmaceutical and Biomedical Analysis, 56 (3). pp. 633-636. ISSN 1873-264X

Buchanan, Hilary A. S. and Meier-Augenstein, Wolfram and Daeid, Niamh Nic and Kerr, William (2011) Organic impurities, stable isotopes, or both : a comparison of instrumental and pattern recognition techniques for the profiling of 3,4-methylenedioxymethamphetamine. Analytical Methods, 3 (10). pp. 2279-2288. ISSN 1759-9660

Bennie, Linsey S. and Fraser, Calum J. and Irvine, Stephanie and Kerr, William J. and Andersson, Shalini and Nilsson, Göran N. (2011) Highly active iridium(I) complexes for the selective hydrogenation of carbon-carbon multiple bonds. Chemical Communications (London), 47 (42). pp. 11653-11655. ISSN 0009-241X

Lindsay, David and Kerr, William (2011) Cobalt close-up. Nature Chemistry, 3. p. 494. ISSN 1755-4330

Farwick, Andreas and Engelhart, Jens and Tverskoy, Olena and Welter, Carolin and Umlauf, Quendolin and Rominger, Frank and Kerr, William and Helmchen, Gunter (2011) Bicyclic cyclopentenones via the combination of an iridium- catalyzed allylic substitution with a diastereoselective intramolecular Pauson–Khand reaction. Advanced Synthesis and Catalysis, 353 (2-3). pp. 349-370. ISSN 1615-4150

Kerr, William and Middleditch, Michael and Watson, Allan (2011) New potentially chelating chiral magnesium amide bases for use in enantioselective deprotonation reactions. Synlett (2). pp. 177-180. ISSN 0936-5214

Bennie, Linsey Sarah and Kerr, William and Middleditch, Michael and Watson, Allan (2011) Towards energetically viable asymmetric deprotonations : selectivity at more elevated temperatures with C2-symmetric magnesium bisamides. Chemical Communications (London), 47 (8). pp. 2264-2266. ISSN 0009-241X

2010

Nilsson, G.N. and Kerr, W.J. (2010) The development and use of novel iridium complexes as catalysts for ortho-directed hydrogen isotope exchange reactions. Journal of Labelled Compounds and Radiopharmaceuticals, 53 (11-12). pp. 662-667. ISSN 0362-4803

Kerr, William and Kunalan, Vanitha and Nic Daeid, Niamh (2010) An investigation into the ability of three analytical techniques to discriminate batches of methylamphetamine prepared by seven synthetic routes. In: 20th International Symposium on the Forensic Sciences of the Australian and New Zealand Forensic Science Society, 2010-09-05 - 2010-09-09.

Kennedy, Alan R. and Kerr, William J. and Paterson, Laura C. and Sutherland, Andrew (2010) A tetrahydropentaleno[1,6a-a]naphthalen-4(2H)-one of defined relative stereochemistry for use towards Agariblazeispirol C. Acta Crystallographica Section C: Crystal Structure Communications, 66. pp. 473-474. ISSN 0108-2701

Paterson, Laura C and Kerr, William J and Sutherland, Andrew (2010) Towards the total synthesis of Agariblazeispirol C. Abstracts of papers - American Chemical Society, 240. ORGN-118.

Buchanan, Hilary A.S. and Daeid, Niamh Nic and Kerr, William J. and Carter, James F. and Hill, Jenny C. (2010) Role of five synthetic reaction conditions on the stable isotopic composition of 3,4-methylenedioxymethamphetamine. Analytical Chemistry, 82 (13). pp. 5484-5489. ISSN 0003-2700

Kędzia, Jacek L. and Kerr, William J. and McPherson, Allan R. (2010) Regioselective Pauson-Khand processes with olefins possessing extended phosphonates. Synlett, 2010 (4). pp. 649-653. ISSN 0936-5214

Burns, Alan R. and Kerr, Jennifer H. and Kerr, William J. and Passmore, Joanna and Paterson, Laura C. and Watson, Allan J. B. (2010) Tuned methods for conjugate addition to a vinyl oxadiazole; synthesis of pharmaceutically important motifs. Organic and Biomolecular Chemistry, 8 (12). pp. 2777-2783. ISSN 1477-0520

2009

Kunalan, Vanitha and Nic Daeid, Niamh and Kerr, W.J. and Buchanan, Hilary A.S. and McPherson, Allan R. (2009) Characterization of route specific impurities found in methamphetamine synthesized by the Leuckart and reductive amination methods. Analytical Chemistry, 81 (17). pp. 7342-7348. ISSN 0003-2700

2008

Gibson, L.T. and Kerr, W.J. and Nordon, A. and Reglinski, J. and Robertson, C. and Turnbull, L. and Watt, C.M. and Cheung, A. and Johnstone, W. (2008) On-site determination of formaldehyde : a low cost measurement device for museum environments. Analytica Chimica Acta, 623 (1). pp. 109-116. ISSN 0003-2670

Kerr, William J. and Watson, Allan J. B. and Hayes, Douglas. (2008) Di-tert-butylmagnesium as an atom-efficient, carbon-centred base reagent for the preparation of silyl enol ethers from ketones. Synlett, 2008 (9). pp. 1386-1390. ISSN 0936-5214

Buchanan, Hilary A.S. and Daeid, N.N. and Meier-Augenstein, Wolfram and Kemp, Helen F. and Kerr, W.J. and Middleditch, Michael (2008) Emerging use of isotope ratio mass spectrometry as a tool for discrimination of 3,4-methylenedioxymethamphetamine by synthetic route. Analytical Chemistry, 80 (9). pp. 3350-3356. ISSN 0003-2700

Irvine, S. and Kerr, W.J. and McPherson, A.R. and Pearson, C.M. (2008) Approaching ambient temperatures in 1,2-dce to deliver efficient intermolecular dotz benzannulation processes. Tetrahedron, 64 (5). pp. 926-935. ISSN 0040-4020

Brown, J.A. and Irvine, S. and Kennedy, A.R. and Kerr, W.J. and Andersson, S. and Nilsson, G.N. (2008) Highly active iridium (I) complexes for catalytic hydrogen isotope exchange. Chemical Communications (London), 2008 (9). pp. 1115-1117. ISSN 0009-241X

Kerr, William J. and Watson, Allan J. B. and Hayes, Douglas. (2008) In situ generation of Mes2Mg as a non-nucleophilic carbon-centred base reagent for the efficient one-pot conversion of ketones to silyl enol ethers. Organic and Biomolecular Chemistry, 6 (7). pp. 1238-1243. ISSN 1477-0520

Kerr, William J. and Pazicky, Marek and McArthur, Duncan. (2008) Recyclable supported chiral amines for use within highly efficient asymmetric Mg-amide base processes. In: Asymmetric Reactions and Syntheses, 2008-08-17.

2007

Kerr, William J. and Watson, Allan J. B. and Hayes, Douglas. (2007) Bismesitylmagnesium: a thermally stable and non-nucleophilic carbon-centered base reagent for the efficient preparation of silyl enol ethers. Chemical Communications (47). pp. 5049-5051. ISSN 1359-7345

2006

Kerr, W.J. and Crawford, J.J. and Henderson, K.W. (2006) Direct and efficient one-pot preparation of ketones from aldehydes using n-tert-butylphenylsulfinimidoyl chloride. Organic Letters, 8 (22). pp. 5073-5076. ISSN 1523-7060

Kerr, W.J. and Pearson, C.M. and Thurston, G.J. (2006) Highly efficient methods for the one-pot synthesis of b-substituted enones. Organic and Biomolecular Chemistry, 4. pp. 47-50.

Kerr, W.J. and Crawford, J.J. and McLaughlin, M. and Pauson, P.L. and Morrison, A.J. and Thurston, G.J. (2006) Use of a highly effective intramolecular Pauson-Khand cyclisation for the formal total synthesis of (+/-) alpha- and beta- cedrene by preparation of cedrone. Tetrahedron, 62. pp. 11360-11370. ISSN 0040-4020

2002

Kerr, W.J. and Henderson, K.W. and Moir, J.H. (2002) Magnesium amide base-mediated enantioselective deprotonation processes. Tetrahedron, 58 (23). pp. 4573-4587. ISSN 0040-4020

Kerr, W.J. and Hutchinson, E.J. and Magennis, E.J. (2002) The microwave-assisted Dötz benzannulation process. Chemical Communications (London), 2002. pp. 2262-2263. ISSN 0009-241X

2001

Kerr, W.J. and McLaughlin, M. and Morrison, A.J. and Pauson, P.L. (2001) Formal total synthesis of (+/-)-alpha- and beta-cedrene by preparation of cedrone. construction of the tricyclic carbon skeleton by the use of a highly efficient intramolecular khand annulation. Organic Letters, 3 (19). pp. 2945-2948. ISSN 1523-7060

2000

Kennedy, A.R. and Kerr, W.J. and Lindsay, D.M. and Scott, J.S. and Watson, S.P. (2000) Stereochemical and mechanistic features of asymmetric Pauson-Khand processes. Journal of the Chemical Society, Perkin Transactions 1, 2000 (24). pp. 4366-4372. ISSN 1472-7781

1999

Armstrong, D.R. and Henderson, K.W. and Kennedy, A.R. and Kerr, W.J. and Mair, F.S. and Moir, J.H. and Moran, P.H. and Snaith, R. (1999) Structural Studies of the Chiral Lithium Amides [{PhC(H)Me}2NLi] and [PhCH2{PhC(H)Me}NLi.THF Derived from a-Methybenzylamine. Journal of the Chemical Society, Dalton Transactions, 1999 (22). pp. 4063-4068. ISSN 0300-9246

Kennedy, Alan and Henderson, Kenneth W. and Kerr, William and Moran, Paul (1999) Redetermination of di- -bromo-bis[(N,N,N',N'-tetramethylethylenediamine-N,N')lithium]. Acta Crystallographica Section C: Crystal Structure Communications, 55. IUC9900078. ISSN 0108-2701

1996

Kennedy, A.R. and Kerr, W.J. and McKendry, S. (1996) 4-Cyclohexanespiro{3-[2-methoxy-2-(2,6-dimethoxyphenyl)ethenyl]ox- etan-2-one}. Acta Crystallographica Section C: Crystal Structure Communications, 53 (6). pp. 746-748. ISSN 0108-2701

This list was generated on Sun Dec 22 11:05:13 2024 GMT.