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2024
Tyerman, Seb and Robertson, Craig M. and Murphy, John A. (2024) Radical coupling of aryl halides to arenes facilitated by Ni(COD)(DQ) and other nickel sources. Organic and Biomolecular Chemistry, 22 (5). pp. 1023-1026. ISSN 1477-0520
Clark, Kenneth F. and Tyerman, Seb and Evans, Laura and Robertson, Craig M. and Murphy, John A. (2024) An assay for aryl radicals using BHAS coupling. Organic and Biomolecular Chemistry, 22 (5). pp. 1018-1022. ISSN 1477-0520
2022
Hutchings, Michael G. and Lawrence, Anthony and Kennedy, Alan R. (2022) Colour and constitution of conjugate bases of benzodifurantrione, its ring-opened derivatives and benzodifuranone dye analogues. Organic and Biomolecular Chemistry, 20 (13). pp. 2661-2670. ISSN 1477-0520
2019
Clark, Peter R. and Williams, Glynn D. and Tomkinson, Nicholas C. O. (2019) Copper-catalysed C-H functionalisation gives access to 2-aminobenzimidazoles. Organic and Biomolecular Chemistry, 17 (34). pp. 7943-7955. ISSN 1477-0520
2018
Wilson, Kirsty L. and Murray, Jane and Jamieson, Craig and Watson, Allan J. B. (2018) Cyrene as a bio-based solvent for HATU mediated amide coupling. Organic and Biomolecular Chemistry (16). pp. 2851-2854. ISSN 1477-0520
2017
Emery, Katie J. and Tuttle, Tell and Murphy, John A. (2017) Evidence of single electron transfer from the enolate anion of an N,N'-dialkyldiketopiperazine additive in BHAS coupling reactions. Organic and Biomolecular Chemistry, 15 (41). pp. 8810-8819. ISSN 1477-0520
Sasselli, I. R. and Moreira, I. P. and Ulijn, R. V. and Tuttle, T. (2017) Molecular dynamics simulations reveal disruptive self-assembly in dynamic peptide libraries. Organic and Biomolecular Chemistry. ISSN 1477-0520
Casals-Cruañas, Èric and Gonzalez-Belman, Oscar F. and Besalú-Sala, Pau and Nelson, David James and Poater, Albert (2017) The preference for dual-gold(I) catalysis in the hydro(alkoxylation vs phenoxylation) of alkynes. Organic and Biomolecular Chemistry. pp. 1-10. ISSN 1477-0520
Waller, J. and Toogood, H. S. and Karuppiah, V. and Rattray, N. J. W. and Mansell, D. J. and Leys, D. and Gardiner, J. M. and Fryszkowska, A. and Ahmed, S. T. and Bandichhor, R. and Reddy, G. P. and Scrutton, N. S. (2017) Structural insights into the ene-reductase synthesis of profens. Organic and Biomolecular Chemistry, 15 (20). pp. 4440-4448. ISSN 1477-0520
Cumine, Florimond and Zhou, Shengze and Tuttle, Tell and Murphy, John A. (2017) A study of diketopiperazines as electron-donor initiators in transition metal-free haloarene-arene coupling. Organic and Biomolecular Chemistry, 15. 3324 - 3336. ISSN 1477-0520
McPherson, Christopher G. and Caldwell, Nicola and Jamieson, Craig and Simpson, Iain and Watson, Allan J. B. (2017) Amidation of unactivated ester derivatives mediated by trifluoroethanol. Organic and Biomolecular Chemistry. ISSN 1477-0520
Emery, Katie J. and Murphy, John A. and Tuttle, Tell (2017) Effect of solvent on radical cyclisation pathways : SRN1 vs. aryl-aryl bond forming mechanisms. Organic and Biomolecular Chemistry, 15 (4). pp. 920-927. ISSN 1477-0520
2016
Henry, Sarah L. and Withers, Jamie M. and Singh, Ishwar and Cooper, Jonathan M. and Clark, Alasdair W. and Burley, Glenn A. and Cogdell, Richard J. (2016) DNA-directed spatial assembly of photosynthetic light-harvesting proteins. Organic and Biomolecular Chemistry, 14 (4). pp. 1359-1362. ISSN 1477-0520
Jones, D. Heulyn and Bresciani, Stefano and Tellam, James P. and Wojno, Justyna and Cooper, Anthony W J and Kennedy, Alan R. and Tomkinson, Nicholas C O (2016) Synthesis of dibenzylamino-1-methylcyclohexanol and dibenzylamino-1-trifluoromethylcyclohexanol isomers. Organic and Biomolecular Chemistry, 14 (1). pp. 172-182. ISSN 1477-0520
2015
Kerr, William J. and Lindsay, David M. and Patel, Vipulkumar K. and Rajamanickam, Muralikrishnan (2015) Efficient methods for enol phosphate synthesis using carbon-centred magnesium bases. Organic and Biomolecular Chemistry, 13 (40). pp. 10131-10135. ISSN 1477-0520
Hester, Theodore J. and Dennison, Sarah R. and Baker, Matthew J. and Snape, Timothy J. (2015) Functionalising the azobenzene motif delivers a light-responsive membrane-interactive compound with the potential for photodynamic therapy applications. Organic and Biomolecular Chemistry, 13 (29). pp. 8067-8070. ISSN 1477-0520
Bagley, Mark C. and Dwyer, Jessica E. and Molina, Maria D Beltran and Rand, Alexander W. and Rand, Hayley L. and Tomkinson, Nicholas C. O. (2015) Microwave-assisted synthesis of 3-aminobenzo[b]thiophene scaffolds for the preparation of kinase inhibitors. Organic and Biomolecular Chemistry, 13 (24). pp. 6814-6824. ISSN 1477-0520
Molloy, John J. and Law, Robert P. and Fyfe, James W.B. and Seath, Ciaran P. and Hirst, David J. and Watson, Allan J.B. (2015) A modular synthesis of functionalised phenols enabled by controlled boron speciation. Organic and Biomolecular Chemistry. ISSN 1477-0520
Brazier, John B. and Gibbs, Timothy J. K. and Rowley, Julian H. and Samulis, Leopold and Yau, Sze Chak and Kennedy, Alan R. and Platts, James A. and Tomkinson, Nicholas C. O. (2015) Improving catalyst activity in secondary amine catalysed transformations. Organic and Biomolecular Chemistry, 13 (1). pp. 133-141. ISSN 1477-0520
2014
Kennedy, Alan R and Kerr, William and Moir, Rory and Reid, Marc (2014) Anion effects to deliver enhanced iridium catalysts for hydrogen isotope exchange processes. Organic and Biomolecular Chemistry, 12 (40). pp. 7927-7931. ISSN 1477-0520
Miah, A.H. and Copley, R.C.B. and O'Flynn, D. and Percy, J.M. and Procopiou, P.A. (2014) Lead identification and structure-activity relationships of heteroarylpyrazole arylsulfonamides as allosteric CC-chemokine receptor 4 (CCR4) antagonists. Organic and Biomolecular Chemistry, 12 (11). pp. 1779-1792. ISSN 1477-0520
Cochrane, A R and Idziak, C and Kerr, William and Mondal, Bhaskar and Paterson, Laura C and Tuttle, Tell and Andersson, S. and Nilsson, G.N. (2014) Practically convenient and industrially-aligned methods for iridium-catalysed hydrogen isotope exchange processes. Organic and Biomolecular Chemistry, 12 (22). pp. 3598-3603. ISSN 1477-0520
Nelson, David J and Fernández-Salas, José A and Truscott, Byron J and Nolan, Steven P. (2014) Iridium(I) hydroxides in catalysis : rearrangement of allylic alcohols to ketones. Organic and Biomolecular Chemistry. ISSN 1477-0520
2013
Farwaha, Hardeep S and Bucher, Gotz and Murphy, John A (2013) A novel neutral organic electron donor with record half-wave potential. Organic and Biomolecular Chemistry, 11. pp. 8073-8081. ISSN 1477-0520
Candelaresi, Marco and Gumiero, Andrea and Adamczyk, Katrin and Robb, Kirsty and Bellota-Antón, César and Sangal, Vartul and Munnoch, John and Greetham, Gregory M and Towrie, Michael and Hoskisson, Paul A and Parker, Anthony W and Tucker, Nicholas P and Walsh, Martin A and Hunt, Neil T (2013) A structural and dynamic investigation of the inhibition of catalase by nitric oxide. Organic and Biomolecular Chemistry, 11 (44). pp. 7778-7788. ISSN 1477-0520
Muir, Calum William and Kennedy, Alan and Redmond, Joanna and Watson, Allan (2013) Synthesis of functionalised 4H-quinolizin-4-ones via tandem Horner–Wadsworth–Emmons olefination/cyclisation. Organic and Biomolecular Chemistry, 11 (20). pp. 3337-3340. ISSN 1477-0520
Rowley, Julian and Yau, Sze Chak and Kariuki, Benson M and Kennedy, Alan and Tomkinson, Nick (2013) Readily accessible chiral at nitrogen cage structures. Organic and Biomolecular Chemistry, 11 (13). pp. 2198-2205. ISSN 1477-0520
Rawling, Michael and Tomkinson, Nick (2013) Metal-free syn-dioxygenation of alkenes. Organic and Biomolecular Chemistry, 11 (9). pp. 1434-1440. ISSN 1477-0520
2012
Smithen, Deborah and Mathews, Christopher and Tomkinson, Nick (2012) Asymmetric alpha-oxyacylation of cyclic ketones. Organic and Biomolecular Chemistry, 10 (18). pp. 3756-3762. ISSN 1477-0520
Brown, Jack A and Chudasama, Vijay and Giles, Melvyn E and Gill, Duncan M and Keegan, Philip S and Kerr, William J and Munday, Rachel H and Griffin, Karen and Watts, Andrew (2012) E- and Z-Stereoselectivity in the preparation of enamides from glycidyl sulfonamides and carbamates. Organic and Biomolecular Chemistry, 10 (3). pp. 509-511. ISSN 1477-0520
Murphy, John A. and Zhou, Sheng-Ze and Jolly, Phillip I and Fleary-Roberts, Nadia and O'Sullivan, Steven and Doni, Eswararao (2012) Reactions of triflate esters and triflamides with an organic neutral super-electron-donor. Organic and Biomolecular Chemistry, 10. pp. 5807-5810. ISSN 1477-0520
2011
Sword, Ryan and Baldwin, Luke A. and Murphy, John A. (2011) Fragmentations observed in the reactions of a-methoxy-c-alkoxyalkyl iodide substrates with super-electron-donors derived from 4-DMAP and N-methylbenzimidazole. Organic and Biomolecular Chemistry, 9 (9). pp. 3560-3570. ISSN 1477-0520
Kyne, Sara H and Percy, Jonathan M and Pullin, Robert D C and Redmond, Joanna M and Wilson, Peter G (2011) One-pot near-ambient temperature syntheses of aryl(difluoroenol) derivatives from trifluoroethanol. Organic and Biomolecular Chemistry, 9 (24). pp. 8328-8339. ISSN 1477-0520
Kyne, S. H. and Aitken, H. M. and Schiesser, C. H. and Lacote, E. and Malacria, M. and Ollivier, C. and Fensterbank, L. (2011) Intramolecular homolytic substitution of sulfinates and sulfinamides : a computational study. Organic and Biomolecular Chemistry, 9 (9). pp. 3331-3337. ISSN 1477-0520
2010
McInnes, F.J. and Anthony, N.G. and Kennedy, Alan R. and Wheate, Nial J. (2010) Solid state stabilisation of the orally delivered drugs atenolol, glibenclamide, memantine and paracetamol through their complexation with cucurbit[7]uril. Organic and Biomolecular Chemistry, 8 (4). pp. 765-773. ISSN 1477-0520
Burns, Alan R. and Kerr, Jennifer H. and Kerr, William J. and Passmore, Joanna and Paterson, Laura C. and Watson, Allan J. B. (2010) Tuned methods for conjugate addition to a vinyl oxadiazole; synthesis of pharmaceutically important motifs. Organic and Biomolecular Chemistry, 8 (12). pp. 2777-2783. ISSN 1477-0520
Besenius, P. and Cormack, P.A.G. and Ludlow, R.F. and Otto, S.R. and Sherrington, D.C. (2010) Affinity chromatography in dynamic combinatorial libraries: one-pot amplification and isolation of a strongly binding receptor. Organic and Biomolecular Chemistry, 8 (10). pp. 2414-2418. ISSN 1477-0520
2009
Gibson, Colin L. and Huggan, J.K. and Kennedy, Alan and Kiefer, L. and Lee, Jeong Hwan and Suckling, C.J. and Clements, Caorl J. and Harvey, Alan L. and Hunter, William N. and Tulloch, Lindsay B. (2009) Diversity oriented syntheses of fused pyrimidines designed as potential antifolates. Organic and Biomolecular Chemistry, 7 (9). pp. 1829-1842. ISSN 1477-0520
Anthony, N.G. and Breen, D. and Donoghue, G. and Khalaf, A.I. and Mackay, S.P. and Parkinson, J.A. and Suckling, C.J. (2009) A new synthesis of alkene-containing minor-groove binders and essential hydrogen bonding in binding to DNA and in antibacterial activity. Organic and Biomolecular Chemistry, 7 (9). pp. 1843-1850. ISSN 1477-0520
Audouard, Christophe and Bettaney, Kim and Doan, Châu T. and Rinaudo, Giuseppe and Jervis, Peter J. and Percy, Jonathan M. (2009) An appraisal of oxoketene cycloaddition methodology for the synthesis of 2,6-dideoxysugars and fluorinated 2,6-dideoxysugars. Organic and Biomolecular Chemistry, 7 (8). pp. 1573-1582. ISSN 1477-0520
Errey, J.C. and Mann, M.C. and Fairhurst, S.A. and Hill, L. and McNeil, M.R. and Naismith, J.H. and Percy, J.M. and Whitfield, C. (2009) Sugar nucleotide recognition by Klebsiella pneumoniae UDP-D-galactopyranose mutase: Fluorinated substrates, kinetics and equilibria. Organic and Biomolecular Chemistry, 7 (5). pp. 1009-1016. ISSN 1477-0520
Breen, D. and Kennedy, A.R. and Suckling, C.J. (2009) A divergent synthesis of minor groove binders with tail group variation. Organic and Biomolecular Chemistry, 7 (1). pp. 178-186. ISSN 1477-0520
Sheldrake, Helen M and Jamieson, Craig and Pascu, Sofia I and Burton, Jonathan W (2009) Synthesis of the originally proposed structures of elatenyne and an enyne from Laurencia majuscula. Organic and Biomolecular Chemistry, 7 (2). pp. 238-252. ISSN 1477-0520
Anderl, Timo and Audouard, Christophe and Miah, Afjal and Percy, Jonathan M. and Rinaudo, Giuseppe and Singh, Kuldip. (2009) Syntheses of difluorinated carbasugar phosphates from trifluoroethanol. Organic and Biomolecular Chemistry, 7 (24). pp. 5200-5206. ISSN 1477-0520
Caravano, Audrey and Field, Robert A. and Percy, Jonathan M. and Rinaudo, Giuseppe and Roig, Ricard and Singh, Kuldip. (2009) Developing an asymmetric, stereo-divergent route to selected 6-deoxy-6-fluoro-hexoses. Organic and Biomolecular Chemistry, 7 (5). pp. 996-1008. ISSN 1477-0520
2008
Steven, V. and Graham, D. (2008) Oligonucleotide conjugation to a cell-penetrating (tat) peptide by diels-alder cycloaddition. Organic and Biomolecular Chemistry, 6 (20). pp. 3781-3787. ISSN 1477-0520
Kerr, William J. and Watson, Allan J. B. and Hayes, Douglas. (2008) In situ generation of Mes2Mg as a non-nucleophilic carbon-centred base reagent for the efficient one-pot conversion of ketones to silyl enol ethers. Organic and Biomolecular Chemistry, 6 (7). pp. 1238-1243. ISSN 1477-0520
Stones, G. and Tripoli, Régis and McDavid, Colin L. and Roux-Duplatre, Kewin and Kennedy, A.R. and Sherrington, D.C. and Gibson, C.L. (2008) Investigation of macrocyclisation routes to 1,4,7-triazacyclononanes : efficient syntheses from 1,2-ditosylamides. Organic and Biomolecular Chemistry, 6 (2). pp. 374-384. ISSN 1477-0520
2006
Ingram, A.M. and Stirling, Kirsten and Faulds, K. and Moore, B.D. and Graham, D. (2006) Investigation of enzyme activity by SERRS using poly-functionalised benzotriazole derivatives as enzyme substrates. Organic and Biomolecular Chemistry, 4 (15). pp. 2869-2873. ISSN 1477-0520
Kerr, W.J. and Pearson, C.M. and Thurston, G.J. (2006) Highly efficient methods for the one-pot synthesis of b-substituted enones. Organic and Biomolecular Chemistry, 4. pp. 47-50.
Evans, Gareth J. S. and White, Katherine and Platts, James A. and Tomkinson, Nicholas C. O. (2006) Computational study of iminium ion formation: effects of amine structure. Organic and Biomolecular Chemistry, 4 (13). pp. 2616-2627. ISSN 1477-0520
2005
Percy, J.M. and Griffith, G.A. and Pintat, S. and Smith, C.A. and Spencer, N. and Uneyama, E. (2005) Towards novel difluorinated sugar mimetrics; syntheses and conformational analyses of highly-functionalised difluorinated cyclooctenones. Organic and Biomolecular Chemistry, 3. pp. 2701-2712.
Gibbs, Timothy J. K. and Tomkinson, Nicholas C. O. (2005) Aminocatalytic preparation of bisindolylalkanes. Organic and Biomolecular Chemistry, 3 (22). pp. 4043-4045. ISSN 1477-0520
2004
Khalaf, A.I. and Ebrahimabadi, A.H. and Drummond, A.J. and Anthony, N.G. and Mackay, S.P. and Suckling, C.J. and Waigh, R.D. (2004) Synthesis and antimicrobial activity of some netropsin analogues. Organic and Biomolecular Chemistry, 2 (21). pp. 3119-3127. ISSN 1477-0520
Percy, J.M. and Audouard, C. and Fawcett, J. and Griffith, G.A. and Pintat, S. and Smith, C.A. (2004) Synthesis of 4,4-difluoroglycosides using ring-closing metathesis. Organic and Biomolecular Chemistry, 2. pp. 528-541.
Arany, Andrea and Crowley, Patrick J and Fawcett, John and Hursthouse, Michael B. and Kariuki, Benson M and Light, Mark E. and Moralee, Andrew C and Percy, Jonathan and Salafia, Vittoria (2004) Highly-functionalised difluorinated (hydroxymethyl)conduritol analogues via the Diels-Alder reactions of a difluorinated dienophile. Organic and Biomolecular Chemistry, 2 (4). pp. 455-465. ISSN 1477-0520
2003
Stones, G. and Argouarch, G. and Kennedy, A.R. and Sherrington, D.C. and Gibson, C.L. (2003) The synthesis of an isopropyl substituted 1,4,7-triazacyclononane via an in situ sequential macrocyclisation method. Organic and Biomolecular Chemistry, 1 (13). pp. 2357-2363. ISSN 1477-0520
Gibson, C.L. and La Rosa, S. and Suckling, C.J. (2003) A prototype solid phase synthesis of pteridines and related heterocyclic compounds. Organic and Biomolecular Chemistry, 1 (11). pp. 1909-1918. ISSN 1477-0520
Ulijn, R V and Bisek, N and Flitsch, S L (2003) Enzymatic optical resolution via acylation-hydrolysis on a solid support. Organic and Biomolecular Chemistry, 1 (4). pp. 621-622. ISSN 1477-0520
Lizos, D.E. and Murphy, J.A. (2003) Concise synthesis of (±)-horsfiline and (±)-coerulescine by tandem cyclisation of iodoaryl alkenyl azides. Organic and Biomolecular Chemistry, 1 (1). pp. 117-122. ISSN 1477-0520
Guiney, D. and Gibson, C.L. and Suckling, C.J. (2003) Syntheses of highly functionalised 6-substituted pteridines. Organic and Biomolecular Chemistry, 1 (4). pp. 664-675. ISSN 1477-0520
Ulijn, R.V. and Bisek, N. and Halling, P.J. and Flitsch, S.L. (2003) Understanding protease catalysed solid phase peptide synthesis. Organic and Biomolecular Chemistry, 1 (8). pp. 1277-1281. ISSN 1477-0520
Argouarch, G. and Stones, G. and Gibson, C.L. and Kennedy, A.R. and Sherrington, D.C. (2003) Bifurcated, modular syntheses of chiral annulet triazacyclononanes. Organic and Biomolecular Chemistry, 1 (24). pp. 4408-4417. ISSN 1477-0520
Harris, Lisa D. and Platts, James A. and Tomkinson, Nicholas C. O. (2003) Enhanced π···π interactions in α,β-unsaturated carbonyls. Organic and Biomolecular Chemistry, 1 (3). pp. 457-459. ISSN 1477-0520
Percy, J.M. and Hursthouse, M.B. and Spencer, N.S. and Tolley, M. and DiMartino, G. and Light, M.E. (2003) Syntheses of selectively fluorinated cyclodecenones: the first deployment of the neutral oxy-cope rearrangement in organofluorine chemistry. Organic and Biomolecular Chemistry, 1 (24). pp. 4423-4434. ISSN 1477-0520