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2024

Perieteanu, Marina and Rodriguez Garzon, Tayner and McGee, Leah M. C. and Khalaf, Abedawn I. and Suckling, Colin J. and Beveridge, Rebecca and Avery, Vicky M. and Scott, Fraser J. (2024) S-MGBs bearing amidine tail groups are potent, selective antiplasmodial agents. RSC Medicinal Chemistry. ISSN 2632-8682

McGee, Leah M.C. and Carpinteyro Sanchez, Alemao G. and Perieteanu, Marina and Eskandari, Kaveh and Bian, Yan and Mackie, Logan and Young, Louise and Beveridge, Rebecca and Suckling, Colin J. and Roberts, Craig W. and Scott, Fraser J. (2024) Strathclyde Minor Groove Binders (S-MGBs) with activity against Acanthamoeba castellanii. Journal of Antimicrobial Chemotherapy, 79 (9). pp. 2251-2258. ISSN 0305-7453

Riley, Christopher and Ammar, Usama and Alsfouk, Aisha and Anthony, Nahoum G. and Baiget, Jessica and Berretta, Giacomo and Breen, David and Huggan, Judith and Lawson, Christopher and McIntosh, Kathryn and Plevin, Robin and Suckling, Colin J. and Young, Louise C. and Paul, Andrew and Mackay, Simon P. (2024) Design and synthesis of novel aminoindazole-pyrrolo[2,3-b]pyridine inhibitors of IKKα that selectively perturb cellular non-canonical NF-κB signalling. Molecules, 29 (15). 3515. ISSN 1420-3049

Alanazi, S. and Doonan, J. and Lumb, F. E. and Alenzi, N. and Jabbar, S. and Al-Riyami, L. and Suckling, C. J. and Harnett, W. and Watson, D. G. (2024) Reduction in creatine metabolites in macrophages exposed to small molecule analogues of the anti-inflammatory parasitic worm product ES-62. Parasite Immunology, 46 (2). e13026. ISSN 0141-9838

Rodríguez-Fernández, Pablo and Botella, Laure and Cavet, Jennifer S. and Domínguez, Jose and Gutierrez, Maximiliano G. and Suckling, Colin J. and Scott, Fraser J. and Tabernero, Lydia (2024) MptpB inhibitor improves the action of antibiotics against mycobacterium tuberculosis and nontuberculous mycobacterium avium infections. ACS Infectious Diseases, 10 (1). 170–183.

2023

Harnett, Margaret M. and Lumb, Felicity E. and Crowe, Jenny and Doonan, James and Buitrago, Geraldine and Brown, Stephanie and Thom, Gillian and MacDonald, Amy and Suckling, Colin J. and Selman, Colin and Harnett, William (2023) Protection against lung pathology during obesity-accelerated ageing in mice by the parasitic worm product ES-62. Frontiers in Immunology, 14. 1285069. ISSN 1664-3224

2022

Hind, Charlotte and Clifford, Melanie and Woolley, Charlotte and Harmer, Jane and McGee, Leah M. C. and Tyson-Hirst, Izaak and Tait, Henry J. and Brooke, Daniel P. and Dancer, Stephanie J. and Hunter, Iain S. and Suckling, Colin J. and Beveridge, Rebecca and Parkinson, John A. and Sutton, J. Mark and Scott, Fraser J. (2022) Insights into the spectrum of activity and mechanism of action of MGB-BP-3. ACS Infectious Diseases, 8 (12). pp. 2552-2563.

Sutter, Jens and Morton, Alec and Littlejohn, David and Allan, Grant and Cogan, Nicola and Combe, Malcolm and Corrigan, Damion and Cooper, Benjamin and Egan, Kieren and Flowers, Paul and Grez Hidalgo, Pablo and Inns, Tom and Janssen, Xanne and Kleczkowski, Adam and MacBryde, Jillian and Reilly, Grant and Megiddo, Itamar and Mwaura, Samuel and Sharpe, Tim and Sambajee, Pratima and Suckling, Colin and Carver, Mark (2022) Strathclyde Pandemic Research Journeys : Personal Accounts of Research During the Covid Period. University of Strathclyde, Glasgow, UK.

Perieteanu, Marina C. and McGee, Leah M.C. and Shaw, Craig D. and MacMillan, Donna S. and Khalaf, Abedawn I. and Gillingwater, Kirsten and Beveridge, Rebecca and Carter, Katharine C. and Suckling, Colin J. and Scott, Fraser J. (2022) Selective anti-Leishmanial Strathclyde minor groove binders using an N-oxide tail group modification. International Journal of Molecular Sciences, 23 (19). 11912. ISSN 1422-0067

Tentellino, Christian and Tipping, William J. and McGee, Leah M. C. and Bain, Laura M. and Wetherill, Corinna and Laing, Stacey and Tyson-Hirst, Izaak and Suckling, Colin J. and Beveridge, Rebecca and Scott, Fraser J. and Faulds, Karen and Graham, Duncan (2022) Ratiometric imaging of minor groove binders in mammalian cells using Raman microscopy. RSC Chemical Biology, 3 (12). pp. 1403-1415. ISSN 2633-0679

Harnett, Margaret M. and Doonan, James and Lumb, Felicity E. and Crowe, Jenny and Damink, Roel Olde and Buitrago, Geraldine and Duncombe-Moore, Josephine and Wilkinson, Debbie I. and Suckling, Colin J. and Selman, Colin and Harnett, William (2022) The parasitic worm product ES-62 protects the osteoimmunology axis in a mouse model of obesity-accelerated ageing. Frontiers in Immunology, 13. 953053. ISSN 1664-3224

Suckling, Colin J and Hunter, Iain S and Scott, Fraser J (2022) Multitargeted anti-infective drugs : resilience to resistance in the antimicrobial resistance era. Future Drug Discovery, 4 (1). ISSN 2631-3316

Kieswetter, Nathan S. and Ozturk, Mumin and Hlaka, Lerato and Chia, Julius Ebua and Nichol, Ryan J. O. and Cross, Jasmine M. and McGee, Leah and Tyson-Hirst, Izaak and Beveridge, Rebecca and Brombacher, Frank and Carter, Katharine C. and Suckling, Colin J. and Scott, Fraser J. and Guler, Reto (2022) Intranasally administered S-MGB-364 displays antitubercular activity and modulates the host immune response to mycobacterium tuberculosis infection. Journal of Antimicrobial Chemotherapy, 77 (4). pp. 1061-1071. ISSN 0305-7453

2021

Giordani, Federica and Khalaf, Abedawn I. and Gillingwater, Kirsten and Munday, Jane C. and De Koning, Harry P. and Suckling, Colin J. and Barrett, Michael P. and Scott, Fraser J. (2021) Erratum : novel minor groove binders cure animal African trypanosomiasis in an in vivo mouse model (J. Med. Chem. (2019) 62 (6) (3021-3035) DOI: 10.1021/acs.jmedchem.8b01847). Journal of Medicinal Chemistry, 64 (24). 18236. ISSN 0022-2623

Scott, Fraser J. and Suckling, Colin J. (2021) The potential for new and resilient anti-cancer drugs based upon minor groove binders for DNA. Medical Research Archives, 9 (11). 2592. ISSN 2375-1924

Brooke, Daniel P. and McGee, Leah M. C. and Giordani, Federica and Cross, Jasmine M. and Khalaf, Abedawn I. and Irving, Craig and Gillingwater, Kirsten and Shaw, Craig D. and Carter, Katharine C. and Barrett, Michael P. and Suckling, Colin J. and Scott, Fraser J. (2021) Correction : Truncated S-MGBs: towards a parasite-specific and low aggregation chemotype. RSC Medicinal Chemistry, 12 (12). p. 2071.

Corbet, Marlene and Pineda, Miguel A. and Yang, Kun and Tarafdar, Anuradha and McGrath, Sarah and Nakagawa, Rinako and Lumb, Felicity E. and Suckling, Colin J. and Harnett, William and Harnett, Margaret M. and Loukas, Alex (2021) Suppression of inflammatory arthritis by the parasitic worm product ES-62 is associated with epigenetic changes in synovial fibroblasts. PLOS Pathogens, 17 (11). e1010069. ISSN 1553-7366

Brooke, Daniel P. and McGee, Leah M. C. and Giordani, Federica and Cross, Jasmine M. and Khalaf, Abedawn I. and Irving, Craig and Gillingwater, Kirsten and Shaw, Craig D. and Carter, Katharine C. and Barrett, Michael P. and Suckling, Colin J. and Scott, Fraser J. (2021) Truncated S-MGBs : towards a parasite-specific and low aggregation chemotype. RSC Medicinal Chemistry, 12 (8). pp. 1391-1401. ISSN 2040-2511

2020

Borthwick, Jennifer A. and Alemparte, Carlos and Wall, Ian and Whitehurst, Benjamin C. and Argyrou, Argyrides and Burley, Glenn and de Dios-Anton, Paco and Guijarro, Laura and Monteiro, Maria Candida and Ortega, Fatima and Suckling, Colin J and Pichel, Julia Castro and Cacho, Monica and Young, Robert J. (2020) Mycobacterium tuberculosis decaprenylphosphoryl-β- d-ribose oxidase inhibitors : expeditious reconstruction of suboptimal hits into a series with potent in vivo activity. Journal of Medicinal Chemistry, 63 (5). pp. 2557-2576. ISSN 0022-2623

2019

Lumb, Felicity E. and Crowe, Jenny and Doonan, James and Suckling, Colin J. and Selman, Colin and Harnett, Margaret M. and Harnett, William (2019) Synthetic small molecule analogues of the immunomodulatory Acanthocheilonema viteae product ES-62 promote metabolic homeostasis during obesity in a mouse model. Molecular and Biochemical Parasitology, 234. 111232. ISSN 0166-6851

Nichol, Ryan and Khalaf, Abedawn and Sooda, Kartheek and Hussain, Omar and Griffiths, Hollie and Phillips, Roger and Javid, Farideh and Suckling, C. J. and Allison, Simon and Scott, Fraser (2019) Selective in vitro anti-cancer activity of non-alkylating minor groove binders. Medicinal Chemistry Communications, 10 (9). pp. 1620-1634. ISSN 2040-2511

Giordani, Federica and Khalaf, Abedawn I. and Gillingwater, Kirsten and Munday, Jane C. and De Koning, Harry P. and Suckling, Colin J. and Barrett, Michael P. and Scott, Fraser J. (2019) Novel minor groove binders cure animal African trypanosomiasis in an in vivo mouse model. Journal of Medicinal Chemistry, 62 (6). pp. 3021-3035. ISSN 0022-2623

2018

Doonan, James and Thomas, David and Wong, Michelle H. and Ramage, Hazel J. and Al-Riyami, Lamyaa and Lumb, Felicity E. and Bell, Kara S. and Fairlie-Clarke, Karen J. and Suckling, Colin J. and Michelsen, Kathrin S. and Jiang, Hui-Rong and Cooke, Anne and Harnett, Margaret M. and Harnett, William (2018) Failure of the anti-inflammatory parasitic worm product ES-62 to provide protection in mouse models of type I diabetes, multiple sclerosis, and inflammatory bowel disease. Molecules, 23 (10). 2669. ISSN 1420-3049

Suckling, Colin J. and Mukherjee, Sambuddho and Khalaf, Abedawn I. and Narayan, Ashwini and Scott, Fraser J. and Khare, Sonal and Dhakshinamoorthy, Saravanakumar and Harnett, Margaret M. and Harnett, William (2018) Synthetic analogues of the parasitic worm product ES-62 reduce disease development in in vivo models of lung fibrosis. Acta Tropica, 185. pp. 212-218. ISSN 0001-706X

Doonan, James and Lumb, Felicity E. and Pineda, Miguel A. and Tarafdar, Anuradha and Crowe, Jenny and Khan, Aneesah M. and Suckling, Colin J. and Harnett, Margaret M. and Harnett, William (2018) Protection against arthritis by the parasitic worm product ES-62, and its drug-like small molecule analogues, is associated with inhibition of osteoclastogenesis. Frontiers in Immunology, 9. 1016. ISSN 1664-3224

Suckling, Colin J. and Alam, Shahabuddin and Olson, Mark A. and Saikh, Kamal U. and Harnett, Margaret M. and Harnett, William (2018) Small molecule analogues of the parasitic worm product ES-62 interact with the TIR domain of MyD88 to inhibit pro-inflammatory signalling. Scientific Reports, 8. 2123. ISSN 2045-2322

2017

Hlaka, Lerato and Rosslee, Michael-Jon and Ozturk, Mumin and Kumar, Santosh and Parihar, Suraj and Brombacher, Frank and Khalaf, Abedawn and Carter, Katharine and Scott, Fraser and Suckling, Colin and Guler, Reto (2017) Evaluation of minor groove binders (MGBs) as novel anti-mycobacterial agents, and the effect of using non-ionic surfactant vesicles as a delivery system to improve their efficacy. Journal of Antimicrobial Chemotherapy, 72 (12). 3334–3341. ISSN 0305-7453

Suckling, Colin J. and Scott, Fraser and Khalaf, Abedawn and Gillingwater, Kirsten and Morrison, Liam and de Koning, Harry and Barrett, Michael and Giordani, Federica (2017) Minor groove binders for DNA as antitypanosomal agents : the veterinary context. In: 3rd International Electronic Conference on Medicinal Chemistry, 2017-11-01 - 2017-11-30.

Suckling, Colin J. and Scott, Fraser J. (2017) Selectivity in anti-infective minor groove binders. In: 3rd International Electronic Conference on Medicinal Chemistry, 2017-11-01 - 2017-11-30.

Suckling, Colin J. and Khalaf, Abedawn and Scott, Fraser J. and Tucker, Nicholas and Niemenen, Leena and Lemonidis, Kimon and Hunter, Iain S. (2017) Why antibacterial minor groove binders are a good thing. In: 3rd International Electronic Conference on Medicinal Chemistry, 2017-11-01 - 2017-11-30.

Scott, Fraser and Nichol, Ryan J.O. and Khalaf, Abedawn I. and Giordani, Federica and Gillingwater, Kirsten and Ramu, Soumya and Elliott, Alysha and Zuegg, Johannes and Duffy, Paula and Rosslee, Michael-Jon and Hlaka, Lerato and Kumar, Santosh and Ozturk, Mumin and Brombacher, Frank and Barrett, Michael and Guler, Reto and Suckling, Colin J. (2017) An evaluation of minor groove binders as anti-fungal and anti-mycobacterial therapeutics. European Journal of Medicinal Chemistry, 136. pp. 561-572. ISSN 0223-5234

Anthony, Nahoum G. and Baiget, Jessica and Berretta, Giacomo and Boyd, Marie and Breen, David and Edwards, Joanne and Gamble, Carly and Gray, Alexander I. and Harvey, Alan L. and Hatziieremia, Sophia and Ho, Ka Ho and Huggan, Judith K. and Lang, Stuart and Llona-Minguez, Sabin and Luo, Jia Lin and McIntosh, Kathryn and Paul, Andrew and Plevin, Robin J. and Robertson, Murray N. and Scott, Rebecca and Suckling, Colin J. and Sutcliffe, Oliver Brook and Young, Louise C. and MacKay, Simon P. (2017) Inhibitory Kappa B kinase α (IKKα) inhibitors that recapitulate their selectivity in cells against isoform-related biomarkers. Journal of Medicinal Chemistry, 60 (16). pp. 7043-7066. ISSN 0022-2623

Lumb, Felicity E. and Doonan, James and Bell, Kara S. and Pineda, Miguel A. and Corbet, Marlene and Suckling, Colin J. and Harnett, Margaret M. and Harnett, William (2017) Dendritic cells provide a therapeutic target for synthetic small molecule analogues of the parasitic worm product, ES-62. Scientific Reports. 1704. ISSN 2045-2322

Kennedy, Alan R. and Khalaf, Abedawn I. and Scott, Fraser and Suckling, Colin J. (2017) Four pyrrole derivatives used as building blocks in the synthesis of minor-groove binders. Acta Crystallographica Section E: Structure Reports, 73 (2). pp. 254-259. ISSN 1600-5368

2016

Scott, Fraser and Khalaf, Abedawn and Suckling, Colin and Carter, Katharine and Grant, Mary and Henderson, Catherine and Westrop, Gareth and Watson, David (2016) An evaluation of minor groove binders as anti-lung cancer therapeutics. Bioorganic and Medicinal Chemistry Letters, 26 (15). pp. 3478-3486. ISSN 0960-894X

Scott, Fraser J. and Khalaf, Abedawn I. and Duffy, Sandra and Avery, Vicky M. and Suckling, Colin J. (2016) Selective anti-malarial minor groove binders. Bioorganic and Medicinal Chemistry Letters, 26. pp. 3326-3329. ISSN 0960-894X

Janicova, L. and Rzepecka, J. and Rodgers, D.T. and Doonan, J and Bell, K. and Lumb, F.E. and Suckling, C.J. and Harnett, M.M. and Harnett, W. (2016) Testing small molecule analogues of acanthocheilonema viteae immunomodulator ES-62 against clinically relevant allergens. Parasite Immunology, 38 (6). pp. 340-351. ISSN 0141-9838

Scott, Fraser J. and Khalaf, Abedawn I. and Giordani, Federica and Wong, Pui Ee and Duffy, Sandra and Barrett, Michael and Avery, Vicky M. and Suckling, Colin J. (2016) An evaluation of minor groove binders as anti-Trypanosoma brucei brucei therapeutics. European Journal of Medicinal Chemistry, 116. pp. 116-125. ISSN 0223-5234

Borthwick, Jennifer A. and Ancellin, Nicolas and Bertrand, Sophie M. and Bingham, Ryan P. and Carter, Paul S. and Chung, Chun-wa and Churcher, Ian and Dodic, Nerina and Fournier, Charlène and Francis, Peter L. and Hobbs, Andrew and Jamieson, Craig and Pickett, Stephen D. and Smith, Sarah E. and Somers, Donald O'N. and Spitzfaden, Claus and Suckling, Colin J. and Young, Robert J. (2016) Structurally diverse mitochondrial branched chain aminotransferase (BCATm) leads with varying binding modes identified by fragment screening. Journal of Medicinal Chemistry, 59 (6). pp. 2452-2467. ISSN 0022-2623

Westaway, Susan M. and Preston, Alex G. S. and Barker, Michael D. and Brown, Fiona and Brown, Jack A. and Campbell, Matthew and Chung, Chun-Wa and Drewes, Gerard and Eagle, Robert and Garton, Neil and Gordon, Laurie and Haslam, Carl and Hayhow, Thomas G. and Humphreys, Philip G. and Joberty, Gerard and Katso, Roy and Kruidenier, Laurens and Leveridge, Melanie and Pemberton, Michelle and Rioja, Inma and Seal, Gail A. and Shipley, Tracy and Singh, Onkar and Suckling, Colin J. and Taylor, Joanna and Thomas, Pamela and Wilson, David M. and Lee, Kevin and Prinjha, Rab K. (2016) Cell penetrant inhibitors of the KDM4 and KDM5 families of histone lysine demethylases. 2. Pyrido[3,4-d]pyrimidin-4(3H)-one derivatives. Journal of Medicinal Chemistry, 59 (4). pp. 1370-1387. ISSN 0022-2623

Coltherd, J. C. and Rodgers, D. T. and Lawrie, R. E. and Al-Riyami, L. and Suckling, C. J. and Harnett, W. and Harnett, M. M. (2016) The parasitic worm-derived immunomodulator, ES-62 and its drug-like small molecule analogues exhibit therapeutic potential in a model of chronic asthma. Scientific Reports, 6. 19224. ISSN 2045-2322

2015

Rodgers, D. T. and Pineda, M. A. and Suckling, C. J. and Harnett, W. and Harnett, M. M. (2015) Drug-like analogues of the parasitic worm-derived immunomodulator ES-62 are therapeutic in the MRL/Lpr model of systemic lupus erythematosus. Lupus, 24 (13). pp. 1437-1442. ISSN 1477-0962

Bertrand, Sophie M. and Ancellin, Nicolas and Beaufils, Benjamin and Bingham, Ryan P. and Borthwick, Jennifer A. and Boullay, Anne Bénédicte and Boursier, Eric and Carter, Paul S. and Chung, Chun Wa and Churcher, Ian and Dodic, Nerina and Fouchet, Marie Hélène and Fournier, Charlène and Francis, Peter L. and Gummer, Laura A. and Herry, Kenny and Hobbs, Andrew and Hobbs, Clare I. and Homes, Paul and Jamieson, Craig and Nicodeme, Edwige and Pickett, Stephen D. and Reid, Iain H. and Simpson, Graham L. and Sloan, Lisa A. and Smith, Sarah E. and Somers, Donald O N and Spitzfaden, Claus and Suckling, Colin J. and Valko, Klara and Washio, Yoshiaki and Young, Robert J. (2015) The discovery of in vivo active mitochondrial branched-chain aminotransferase (BCATm) inhibitors by hybridizing fragment and HTS hits. Journal of Medicinal Chemistry, 58 (18). pp. 7140-7163. ISSN 0022-2623

Kennedy, Alan R. and Khalaf, Abedawn I. and Scott, Fraser J. and Suckling, Colin J. (2015) Crystal structure of N,N-dimethyl-2-[(4-methylbenzyl) sulfonyl]ethanamine. Acta Crystallographica Section E: Structure Reports, 71 (7). pp. 757-759. ISSN 1600-5368

Suckling, Colin J. (2015) The antibacterial drug MGB-BP3 : from discovery to clinical trial. Chemistry and Biology Interface, 5 (3). pp. 166-174. ISSN 2249-4820

Rzepecka, Justyna and Pineda, Miguel A. and Al-Riyami, Lamyaa and Rodgers, David T. and Huggan, Judith K. and Lumb, Felicity E. and Khalaf, Abedawn I. and Meakin, Paul J. and Corbet, Marlene and Ashford, Michael L. and Suckling, Colin J. and Harnett, Margaret M. and Harnett, William (2015) Prophylactic and therapeutic treatment with a synthetic analogue of a parasitic worm product prevents experimental arthritis and inhibits IL-1β production via NRF2-mediated counter-regulation of the inflammasome. Journal of Autoimmunity, 60. pp. 59-73. ISSN 0896-8411

Al-Riyami, Lamyaa and Rodgers, David T. and Rzepecka, Justyna and Pineda, Miguel A. and Suckling, Colin J. and Harnett, Margaret M. and Harnett, William (2015) Protective effect of small molecule analogues of the Acanthocheilonema viteae secreted product ES-62 on oxazolone-induced ear inflammation. Experimental Parasitology. ISSN 0014-4894 (In Press)

2014

Alniss, Hasan Y. and Salvia, Marie Virginie and Sadikov, Mykhailo and Golovchenko, Igor and Anthony, Nahoum G. and Khalaf, Abedawn I. and MacKay, Simon P. and Suckling, Colin J. and Parkinson, John A. (2014) Recognition of the DNA minor groove by thiazotropsin analogues. Chembiochem, 15 (13). 1978–1990. ISSN 1439-4227

Nieminen, Leena Kaija Linnea and Hunter, Iain and Suckling, Colin and Tucker, Nicholas (2014) The differing biological fates of DNA minor groove-binding (MGB) antibiotics in Gram-negative and Gram-positive bacteria. In: International Congresses of the International Union of Microbiological Societies (IUMS), 2014-07-27 - 2014-08-01, Palais des Congres de Montreal. (Unpublished)

Rzepecka, Justyna and Coates, Michelle and Saggar, Moninder and Al-Riyami, Lamyaa and Coltherd, Jennifer and Tay, Hwee Kee and Huggan, Judith and Janicova, Lucia and Khalaf, Abedawn and Siebeke, Ivonne and Suckling, Colin and Harnett, Margaret and Harnett, William (2014) Small molecule analogues of the immunomodulatory parasitic helminth product ES-62 have anti-allergy properties. International Journal for Parasitology, 44 (9). pp. 669-674. ISSN 0020-7519

Mayer, Günter and Lünse, Christina and Suckling, Colin and Scott, Fraser (2014) Novel TPP-riboswitch activators bypass metabolic enzyme dependency. Frontiers in Chemistry, 2. 53. ISSN 2296-2646 (In Press)

Chreifi, Georges and Li, Huiying and McInnes, Craig and Gibson, Colin and Suckling, Colin and Poulos, Thomas L (2014) Communication between the zinc and tetrahydrobiopterin binding sites in nitric oxide synthase. Biochemistry. ISSN 0006-2960

Lang, Stuart and Khalaf, Abedawn I and Breen, David and Huggan, Judith and Clements, Carol and MacKay, Simon and Suckling, Colin (2014) Oligoamides of 2-amino-5-alkylthiazole 4-carboxylic acids : anti-trypanosomal compounds. Medicinal Chemistry Research, 23 (3). pp. 1170-1179.

Khalaf, Abedawn I and Huggan, Judith and Suckling, Colin J and Gibson, Colin L and Stewart, Kirsten and Giordani, Federica and Barrett, Michael P. and Wong, Pui Ee and Barrack, Keri L and Hunter, William N (2014) Structure based design and synthesis of antiparasitic pyrrolopyrimidines targeting pteridine reductase 1. Journal of Medicinal Chemistry, 57 (15). pp. 6479-6494. ISSN 0022-2623

2013

Salvia, Marie-Virginie and Addison, Fiona and Alniss, Hasan Y H and Buurma, Niklaas J and Khalaf, Abedawn and MacKay, Simon and Anthony, Nahoum G and Suckling, Colin and Evstigneev, Maxim P and Santiago, Adrian Hernandez and Waigh, Roger and Parkinson, John (2013) Thiazotropsin aggregation and its relationship to molecular recognition in the DNA minor groove. Biophysical Chemistry, 179. pp. 1-11. ISSN 0301-4622

Barrett, M.P. and Gemmell, Curtis G and Suckling, Colin (2013) Minor groove binders as anti-infective agents. Pharmacology and Therapeutics, 139 (1). pp. 12-23. ISSN 0163-7258

Suckling, Colin (2013) The diversity-oriented synthesis of pteridines—achievements and potential for development. IUBMB Life, 65 (4). pp. 283-299. ISSN 1521-6543

Bochatay, Valentin and Boissarie, Patrick and Murphy, John A and Suckling, Colin and Lang, Stuart (2013) Mechanistic exploration of the palladium-catalysed process for the synthesis of benzoxazoles and benzothiazoles. Journal of Organic Chemistry, 78 (4). pp. 1471-1477. ISSN 0022-3263

Al-Riyami, Lamyaa and Pineda, Miguel and Rzepecka, Justyna and Huggan, Judith and Khalaf, Abedawn and Suckling, Colin and Rodgers, David and Harnett, Margaret and Harnett, William and Scott, Fraser (2013) Designing anti-inflammatory drugs from parasitic worms: a synthetic small molecule analogue of the Acanthocheilonema viteae product ES-62 prevents development of collagen-induced arthritis : Helminth-based synthetic compound protects against CIA. Journal of Medicinal Chemistry, 56. pp. 9982-10002. ISSN 0022-2623

Parkinson, John A and Scott, Fraser J and Suckling, Colin J and Wilson, Gail (2013) Exceptionally strong intermolecular association in hydrophobic DNA minor groove binders and their potential therapeutic consequences. MedChemComm, 4 (7). pp. 1105-1108.

2012

Anderson, Niall A and Fallon, Brendan J and Valverde, Elena and MacDonald, Simon J F and Pritchard, John M and Suckling, Colin and Watson, Allan (2012) Asymmetric rhodium-catalysed addition of arylboronic acids to acyclic unsaturated esters containing a basic γ-amino group. Synlett, 23 (19). pp. 2817-2821. ISSN 0936-5214

Daff, Simon and Gazur, Ben and Papale, Davide and McInnes, Craig and Morthala, Raghavendar R. and Gibson, Colin L. and Suckling, Colin J. (2012) Tetrahydrobiopterin and electron transfer in NO synthase. Nitric Oxide: Biology and Chemistry, 27 (supple). S5-S5. ISSN 1089-8603

Suckling, Colin (2012) From multiply active natural product to candidate drug? Antibacterial (and other) minor groove binders for DNA. Future Medicinal Chemistry, 4 (8). pp. 971-989. ISSN 1756-8919

Boissarie, Patrick and Hamilton, Zoe and Lang, Stuart and Murphy, John A and Suckling, Colin (2012) Pd-catalyzed three-component synthesis of oxazolines and benzoxazoles. SYNFACTS, 8 (2). p. 138.

Khalaf, Abedawn and Bourdin, Claire and Breen, David and Donoghue, Gavin and Scott, Fraser and Suckling, Colin and MacMillan, Donna and Clements, Carol and Fox, Keith and Sekibo, Doreen (2012) Design, synthesis and antibacterial activity of minor groove binders: the role of non-cationic tail groups. European Journal of Medicinal Chemistry, 56. pp. 39-47. ISSN 0223-5234

Alniss, Hasan Y and Anthony, Nahoum Guillaume Husan and Khalaf, Abedawn and Mackay, Simon and Suckling, Colin and Waigh, Roger and Wheate, Nial and Parkinson, John (2012) Rationalising sequence selection by ligand assemblies in the DNA minor groove : the case for thiazotropsin A. Chemical Science, 3 (3). pp. 711-722. ISSN 2041-6539

2011

Boissarie, Patrick and Hamilton, Zoe and Lang, Stuart and Murphy, John and Suckling, Colin (2011) A powerful palladium-catalyzed multicomponent process for the preparation of oxazolines and benzoxazoles. Organic Letters, 13 (23). pp. 6256-6259. ISSN 1523-7060

Khalaf, Abedawn I and Anthony, Nahoum and Breen, David and Donoghue, Gavin and Mackay, Simon P and Scott, Fraser J and Suckling, Colin J (2011) Amide isosteres in structure-activity studies of antibacterial minor groove binders. European Journal of Medicinal Chemistry, 46 (11). pp. 5343-5355.

Baiget, Jessica and Llona-Minguez, Sabin and Lang, Stuart and MacKay, Simon P. and Suckling, Colin J. and Sutcliffe, Oliver B. (2011) Manganese dioxide mediated one-pot synthesis of methyl 9H-pyrido[3,4-b]indole-1-carboxylate : concise synthesis of alangiobussinine. Beilstein Journal of Organic Chemistry, 7. pp. 1407-1411. ISSN 1860-5397

Lee, Graham and Thomson, D.M. and Suckling, Colin and Morris, B.J. and Pratt, J.A. (2011) Evaluating nitric oxide synthase as a potential therapeutic target in schizophrenia. Journal of Psychopharmacology, 25 (8 Supp). A67-A67. ISSN 1461-7285

Adcock, Jonathan Paul and Gibson, Colin and Huggan, Judith and Suckling, Colin (2011) Diversity oriented synthesis : substitution at C5 in unreactive pyrimidines by Claisen rearrangement and reactivity in nucleophilic substitution at C2 and C4 in pteridines and pyrido[2,3-d]pyrimidines. Tetrahedron, 67 (18). pp. 3226-3237. ISSN 0040-4020

Kunuthur, S. P. and Milliken, P. H. and Gibson, Colin and Suckling, C. J. and Wadsworth, R. M. (2011) Tetrahydrobiopterin analogues with NO-dependent pulmonary vasodilator properties. European Journal of Pharmacology, 650 (1). pp. 371-377. ISSN 0014-2999

2010

Al-Riyami, Lamyaa and Rzepecka, Justyna and Khalaf, Abedawn and Suckling, Colin and Harnett, M. and Harnett, William (2010) Small molecule analogues of an immunomodulatory helminth product provide a novel approach to dissecting macrophage signal transduction pathways : Poster abstract. Immunology, 131 (Supple). p. 164. ISSN 0019-2805

Wittayanarakul, Kitiyaporn and Anthony, Nahoum G. and Treesuwan, Witcha and Hannongbua, Supa and Alniss, Hasan and Khalaf, Abedawn I. and Suckling, Colin J. and Parkinson, John A and Mackay, Simon P. (2010) Ranking ligand affinity for the DNA minor groove by experiment and simulation. Medicinal Chemistry Letters, 1 (8). pp. 376-680. ISSN 1948-5875

Kennedy, Alan and Khalaf, Abedawn I. and Suckling, Colin J. (2010) 2,2,2-Trifluoro-N-(isoquinolin-5-ylmethyl)acetamide. Acta Crystallographica Section E: Structure Reports, 66 (Pt 1). o135. ISSN 1600-5368

McInnes, Craig R. and Suckling, C.J. and Gibson, C.L. and Morthala, Raghavendar R. and Daff, Simon and Gazur, Ben (2010) Blocked dihydropteridines as nitric oxide synthase activators. Pteridines, 20. pp. 27-35. ISSN 0933-4807

Tulloch, Lindsay B. and Martini, Viviane P. and Iulek, Jorge and Huggan, J. and Lee, Jeong Hwan and Gibson, C.L. and Smith, Terry K. and Suckling, C.J. and Hunter, William N. (2010) Structure-based design of pteridine reductase inhibitors targeting African sleeping sickness and the leishmaniases. Journal of Medicinal Chemistry, 53 (1). pp. 221-229. ISSN 0022-2623

2009

Stevenson, Ross and Stokes, Robert J. and MacMillan, Donna and Armstrong, David and Faulds, Karen and Wadsworth, Roger and Kununthur, Suma and Suckling, Colin J. and Graham, Duncan (2009) In situ detection of pterins by SERS. Analyst, 134. pp. 1561-1564. ISSN 0003-2654

Treesuwan, Witcha and Wittayanarakul, Kitiyaporn and Anthony, Nahoum G. and Huchet, Guillaume and Alniss, Hasan and Hannongbua, Supa and Khalaf, Abedawn I. and Suckling, Colin J. and Parkinson, John A. and Mackay, Simon P. (2009) A detailed binding free energy study of 2 : 1 ligand–DNA complex formation by experiment and simulation. Physical Chemistry Chemical Physics, 11 (45). pp. 10682-10693. ISSN 1463-9084

Gibson, Colin L. and Huggan, J.K. and Kennedy, Alan and Kiefer, L. and Lee, Jeong Hwan and Suckling, C.J. and Clements, Caorl J. and Harvey, Alan L. and Hunter, William N. and Tulloch, Lindsay B. (2009) Diversity oriented syntheses of fused pyrimidines designed as potential antifolates. Organic and Biomolecular Chemistry, 7 (9). pp. 1829-1842. ISSN 1477-0520

Anthony, N.G. and Breen, D. and Donoghue, G. and Khalaf, A.I. and Mackay, S.P. and Parkinson, J.A. and Suckling, C.J. (2009) A new synthesis of alkene-containing minor-groove binders and essential hydrogen bonding in binding to DNA and in antibacterial activity. Organic and Biomolecular Chemistry, 7 (9). pp. 1843-1850. ISSN 1477-0520

Parkinson, J.A. and Khalaf, A.I. and Anthony, N.G. and Mackay, S.P. and Suckling, C.J. and Waigh, R.D. (2009) Comparison of DNA complex formation behaviour for two closely related lexitropsin analogues. Helvetica Chimica Acta, 92 (5). pp. 795-822. ISSN 0018-019X

Breen, D. and Kennedy, A.R. and Suckling, C.J. (2009) A divergent synthesis of minor groove binders with tail group variation. Organic and Biomolecular Chemistry, 7 (1). pp. 178-186. ISSN 1477-0520

2008

Gibson, Colin and Kennedy, A.R. and Morthala, R.R. and Parkinson, J.A. and Suckling, C.J. (2008) Tetramic acid and imidazolidinone syntheses via unexpected base induced cyclisations of alanine derived Weinreb amides. Tetrahedron, 64 (32). pp. 7619-7625. ISSN 0040-4020

Suckling, C.J. (2008) Molecular recognition and physicochemical properties in the discovery of selective antibacterial minor groove binders. Journal of Physical Organic Chemistry, 21 (7-8). pp. 575-583. ISSN 0894-3230

Suckling, Colin J. and Gibson, C.L. and Huggan, Judith K. and Morthala, Raghavendar R. and Clarke, Brendan and Kununthur, Suma and Wadsworth, Roger M. and Daff, Simon and Papale, Davide (2008) 6-Acetyl-7,7-dimethyl-5,6,7,8-tetrahydropterin is an activator of nitric oxide synthases. Bioorganic and Medicinal Chemistry Letters, 18 (5). pp. 1563-1566. ISSN 0960-894X

2007

Anthony, Nahoum Guillaume Hsuan and Breen, D. and Clarke, Joanna and Donoghue, Gavin and Drummond, Allan J. and Ellis, Elizabeth and Gemmell, Curtis G. and Helesbeux, Jean-Jacques and Hunter, Iain. S. and Khalaf, Abedawn and MacKay, Simon and Parkinson, J.A. and Suckling, C.J. and Waigh, R.D. (2007) Antimicrobial lexitropsins containing amide, amidine, and alkene linking groups. Journal of Medicinal Chemistry, 50 (24). pp. 6116-6125. ISSN 0022-2623

Suckling, C.J. and Murphy, J.A. and Khalaf, A.I. and Zhou, S. and Lizos, D.E. and Nguyen Van Nhien, A. and Yasumatsu, H. and McVie, A. and Young, L.C. and McCraw, C. and Waterman, P.G. and Morris, B.J. and Pratt, J.A. and Harvey, A. (2007) M4 agonists/5HT7 antagonists with potential as antischizophrenic drugs: serominic compounds. Bioorganic and Medicinal Chemistry Letters, 17 (9). pp. 2649-2655. ISSN 0960-894X

2006

Kennedy, Alan and Khalaf, Abedawn I. and Suckling, Colin J. and Waigh, Roger D. (2006) 3-Nitro-1-(triisopropylsilyl)-1H-pyrrole. Acta Crystallographica Section E: Structure Reports, 62 (8). o3282-o3284. ISSN 1600-5368

Suckling, C.J. and Hampshire, Andrew J. and Khairallah, Hannah and Khalaf, A.I. and Ebrahimabadi, Abdolrasoul H. and Waigh, R.D. and Brown, Tom and Fox, Keith R. (2006) DNA sequence recognition by an imidazole-containing isopropyl thiazole polyamide (thiazotropsin b). Bioorganic and Medicinal Chemistry Letters, 16 (13). pp. 3469-3474.

Clark, R.L. and Johnston, B.F. and Suckling, C.J. and Mackay, S.P. (2006) A modelling study of a non-concerted hydrolytic cycloaddition reaction by the catalytic antibody H11. Bioorganic and Medicinal Chemistry Letters, 14. pp. 2674-2683. ISSN 0960-894X

Gibson, C.L. and Huggan, J.K. and Kennedy, A.R. and Suckling, C.J. (2006) Ethyl 2-({6-amino-2-(benzylsulfanyl)-5-[2-(ethoxycarbonyl)prop-2-enyl]pyrimidin-4-yloxy}methyl)acrylate. Acta Crystallographica Section E: Structure Reports, 62 (1). o324-o326. ISSN 1600-5368

2005

Anthony, Nahoum Guillaume Hsuan and Huchet, Guillaume and Johnston, Blair and Parkinson, John and Suckling, Colin and Waigh, Roger and MacKay, Simon (2005) In Silico Footprinting of Ligands Binding to the Minor Groove of DNA. Journal of Chemical Information and Modeling, 45 (6). pp. 1896-1907. ISSN 1549-9596

Alvarez, R.G. and Kennedy, A.R. and Khalaf, A.I. and Suckling, C.J. and Waigh, R.D. (2005) 2-(1-Piperidinyl)-1,3-benzothiazole. Acta Crystallographica Section E: Structure Reports, 61. pp. 569-570. ISSN 1600-5368

Suckling, C.J. and Huggan, J. and Berlouis, L. and Gibson, C.L. (2005) Electrochemical properties of blocked dihydropterins. Pteridines, 16 (112). ISSN 0933-4807

Suckling, C.J. and Huggan, J. and Rao, R.M. and Kiefer, L. and Gibson, C.L. (2005) Highly flexible solid phase syntheses of pteridines and related compounds. Pteridines, 16 (88). ISSN 0933-4807

Suckling, C.J. and Huggan, J. and Rao, R.M. and Kiefer, L. and Gibson, C.L. (2005) Highly flexible syntheses of pteridines and related compounds. Pteridines, 16 (53). ISSN 0933-4807

Suckling, C.J. and Kununthur, S.R. and Gibson, C.L. and Wadsworth, R.M. (2005) Modulation of pulmonary vascular tone by novel analogues of tetrahydrobiopterin. Pteridines, 16 (112). ISSN 0933-4807

2004

Suckling, C.J. (2004) Minor groove binders 1998-2004. Expert Opinion on Therapeutic Patents, 14 (12). pp. 1693-1724. ISSN 1354-3776

Khalaf, A.I. and Ebrahimabadi, A.H. and Drummond, A.J. and Anthony, N.G. and Mackay, S.P. and Suckling, C.J. and Waigh, R.D. (2004) Synthesis and antimicrobial activity of some netropsin analogues. Organic and Biomolecular Chemistry, 2 (21). pp. 3119-3127. ISSN 1477-0520

Anthony, N.G. and Johnston, B.F. and Khalaf, A.I. and Mackay, S.P. and Parkinson, J.A. and Suckling, C.J. and Waigh, R.D. (2004) Short Lexitropsin that Recognizes the DNA Minor Groove at 5'-ACTAGT-3': Understanding the Role of Isopropyl-thiazole. Journal of the American Chemical Society, 126 (36). pp. 11338-11349. ISSN 1520-5126

Kennedy, Alan R. and Khalaf, Abedawn I. and Suckling, Colin J. and Waigh, Roger D. (2004) Methyl 2-amino-5-iso­propyl-1,3-thia­zole-4-carboxyl­ate. Acta Crystallographica Section E: Structure Reports, 60 (9). pp. 1510-1512. ISSN 1600-5368

Anthony, N.G. and Johnston, B.F. and Mackay, S.P. and Suckling, C.J. and Waigh, R.D. (2004) An in silico footprinting technique to study ligand interactions in the minor groove of DNA. Drugs of the Future, 29 (Suppl.). p. 150. ISSN 0377-8282

Kennedy, A.R. and Khalaf, A.I. and Suckling, C.J. and Waigh, R.D. (2004) Ethyl 2-amino-4-isopropyl-1,3-thiazole-5-carboxylate. Acta Crystallographica Section E: Structure Reports, 60 (8). pp. 1188-1190. ISSN 1600-5368

James, P.L. and Merkina, E.E. and Khalaf, A.I. and Suckling, C.J. and Waigh, R.D. and Brown, T. and Fox, K.R. (2004) DNA sequence recognition by an isopropyl substituted thiazole polyamide. Nucleic Acids Research, 32 (11). pp. 3410-3417. ISSN 1362-4962

Anthony, N.G. and Fox, K.R. and Johnston, B.F. and Khalaf, A.I. and Mackay, S.P. and McGroarty, I.S. and Parkinson, J.A. and Skellern, G.G. and Suckling, C.J. and Waigh, R.D. (2004) DNA binding of a short lexitropsin. Bioorganic and Medicinal Chemistry Letters, 14 (5). pp. 1353-1356. ISSN 0960-894X

Khalaf, A.I. and Waigh, R.D. and Drummond, A.J. and Pringle, B. and McGroarty, I. and Skellern, G.G. and Suckling, C.J. (2004) Distamycin Analogues with Enhanced Lipophilicity: Synthesis and Antimicrobial Activity. Journal of Medicinal Chemistry, 47 (8). pp. 2133-2156. ISSN 0022-2623

Gibson, C.L. and La Rosa, S. and Ohta, K. and Boyle, P.H. and Leurquin, F. and Lemaçon, A. and Suckling, C.J. (2004) The synthesis of 7-deazaguanines as potential inhibitors of guanosine triphosphate cyclohydrolase 1. Tetrahedron, 60 (4). pp. 943-959. ISSN 0040-4020

Suckling, C.J. and Gibson, C.L. and Huggan, J. and Oppilliart, S. and La Rosa, S.; Epton, R., ed. (2004) Solid phase synthesis of pteridines and related compounds. In: 8th Millennium Symposium, Solid Phase Synthesis and Combinational Libraries. Mayflower, pp. 39-42.

2003

Kennedy, A.R. and Khalaf, A.I. and Suckling, C.J. and Waigh, R.D. (2003) Ethyl 5-oxo-2,5-dihydro-4-isoxazolecarboxylate hydroxylamine salt. Acta Crystallographica Section E: Structure Reports, 59 (9). pp. 1410-1412. ISSN 1600-5368

Suckling, C.J. and Waigh, R.D. and Khalaf, A.L. and Parkinson, J. and Hunter, I.S.; Williams, R.M., ed. (2003) Minor groove binders substituted by lipophilic groups. In: 19th International Congress on Heterocyclic Chemistry. Elsevier, p. 98. ISBN 0-080443-04-4

Suckling, C.J. and Gibson, C.L. and La Rosa, S. and Huggan, J. and Oppilliart, S.; Williams, R.M., ed. (2003) Solid phase synthesis of pteridines and related compounds. In: 19th International Congress on Heterocyclic Chemistry. Elsevier, p. 322. ISBN 0-080443-04-4

Gibson, C.L. and La Rosa, S. and Suckling, C.J. (2003) A prototype solid phase synthesis of pteridines and related heterocyclic compounds. Organic and Biomolecular Chemistry, 1 (11). pp. 1909-1918. ISSN 1477-0520

Gibson, C.L. and La Rosa, S. and Suckling, C.J. (2003) A traceless solid-phase synthesis of pteridines. Tetrahedron Letters, 44 (6). pp. 1267-1270. ISSN 0040-4039

Guiney, D. and Gibson, C.L. and Suckling, C.J. (2003) Syntheses of highly functionalised 6-substituted pteridines. Organic and Biomolecular Chemistry, 1 (4). pp. 664-675. ISSN 1477-0520

2002

Littlejohn, A. and Suckling, C.J. and Campbell, L. and McNicol, D. (2002) The amazingly patient tutor: students' interactions with an online carbohydrate chemistry course. British Journal of Educational Technology, 33 (3). pp. 313-321. ISSN 0007-1013

La Rosa, S. and Boyle, P.H. and Suckling, C.J. and Gibson, C.L. and Guiney, D.; (2002) Solution and solid phase synthesis of pteridines, purides and related compounds. In: The Chemistry and Biology of Pteridines and Folates. Kluwer Academic Publishers, UK, pp. 25-29. ISBN 0-792376-75-7

Gibson, C.L. and Boyle, P.H. and Guiney, D. and La Rosa, S. and Suckling, C.J.; (2002) Strategies for the synthesis of pteridines and related compounds with high diversity. In: The Chemistry and Biology of Pteridines and Folates. Kluwer Academic Publishers, pp. 421-425. ISBN 0-792376-75-7

Guiney, D. and Boyle, P.H. and Gibson, C.L. and La Rosa, S. and Suckling, C.J.; (2002) Synthesis of Pteridines with C-2 and C-6 functional group diversity. In: The Chemistry and Biology of Pteridines and Folates. Kluwer Academic Publishers, pp. 31-35. ISBN 0-792376-75-7

2001

Alvarez, Ricardo G. and Hunter, Iain S. and Suckling, Colin J. and Thomas, Michael and Vitinius, Ute (2001) A novel biotransformation of benzofurans and related compounds catalysed by a chloroperoxidase. Tetrahedron, 57 (40). pp. 8581-8587. ISSN 0040-4020

Kennedy, Alan and Khalaf, Abedawn and Suckling, Colin and Waigh, Roger (2001) Ethyl 2-aminooxazole-5-carboxylate. Acta Crystallographica Section E: Structure Reports, 57. o832-o833. ISSN 1600-5368

2000

Khalaf, A.I. and Alvarez, R.G. and Suckling, C.J. and Waigh, R.D. (2000) Unexpected Dealkylation During Nucleophilic Substitution: Synthesis of 2-N,N-Dialkylamino Benzoxazoles and Benzothiazoles. Tetrahedron, 56 (43). pp. 8567-8571. ISSN 0040-4020

Khalaf, A.I. and Pitt, A.R. and Scobie, M. and Suckling, C.J. and Urwin, J. and Waigh, R.D. and Young, S.C. and Fishleigh, R.V. and Fox, K.R. (2000) DNA Binding, Solubility, and Partitioning Characteristics of Extended Lexitropsins. Journal of Medicinal Chemistry, 43 (17). pp. 3257-3266. ISSN 0022-2623

Khalaf, A.I. and Pitt, A.R. and Scobie, M. and Suckling, C.J. and Urwin, J. and Waigh, R.D. and Young, S.C. and Fishleigh, R.V. and Wylie, W.A. (2000) The Synthesis of Some Head to Head Linked DNA Minor Groove Binders. International Journal of Chemical Research, 56 (29). pp. 5225-5239. ISSN 0975-3699

Suckling, C.J. and Gibson, C.L. and McCluskey, A.; (2000) Synthesis of Pyrimidine Libraries: Development of Solid Phase Methodology. In: Solid Phase Synthesis and Combinatorial Chemical Libraries. Mayflower Press, pp. 359-360. ISBN 0471331953 (Unpublished)

Khalaf, A.I. and Pitt, A.R. and Scobie, M. and Suckling, C.J. and Urwin, J. and Waigh, R.D. and Young, S.C. and Fishleigh, R.V. (2000) The synthesis of some indole-containing amino acids as linkers for the construction of DNA minor groove binders. International Journal of Chemical Research, 2000 (6). pp. 264-265. ISSN 0975-3699

Kennedy, A.R. and Khalaf, A.I. and Suckling, C.J. (2000) 3-Acetoxycyclohex-4-ene-1,2-di-carboxylic anhydride. Acta Crystallographica Section C: Crystal Structure Communications, 56 (6). e265-e266. ISSN 0108-2701

Khalaf, Abedawn I. and Linaza, Sabin and Pitt, Andrew R. and Stimson, William H. and Suckling, Colin J. (2000) On the specificity of reactions catalysed by the antibody H11. Tetrahedron, 56 (3). pp. 489-495. ISSN 0040-4020

Khalaf, Abedawn I. and Pitt, Andrew R. and Scobie, Martin and Suckling, Colin J. and Urwin, John and Waigh, Roger D. and Fishleigh, Robert V. and Young, Stephen C. (2000) Synthesis of novel DNA binding agents: indole-containing analogs of bis-netropsin. International Journal of Chemical Research (6). pp. 264-265. ISSN 0975-3699

1999

Kennedy, A.R. and Pitt, A.R. and Suckling, C.J. and Suckling, K.E. and Thomas, M. (1999) Cholest-5-ene-3 beta,4 beta-diyl diacetate. Acta Crystallographica Section C: Crystal Structure Communications, 55 (9). pp. 1570-1572. ISSN 0108-2701

Kennedy, Alan and Khalaf, Abedawn I. and Pitt, Andrew P. and Scobie, Martin and Suckling, Colin J. and Urwin, John and Waigh, Roger D. and Young, Stephen C. (1999) Methyl 2-amino-4-(methoxymethyl)thiazole-5-carboxylate. Acta Crystallographica Section C: Crystal Structure Communications, C55 (7). ii, IUC9900072. ISSN 0108-2701

1992

Khalaf, Abedawn I. and Proctor, George R. and Suckling, Colin J. and Bence, Laura H. and Irvine, June I. and Stimson, William H. (1992) Remarkably efficient hydrolysis of a 4-nitrophenyl ester by a catalytic antibody raised to an ammonium hapten. Journal of the Chemical Society, Perkin Transactions 1 (12). pp. 1475-1481. ISSN 1472-7781

1991

Reid, David G. and MacLachlan, L.K. and Suckling, K.E. and Gee, A. and Cresswell, S. and Suckling, C.J. (1991) A f-19 and deuterium nmr-study of two novel fluorosterols and their properties in model membranes and high-density-lipoprotein. Chemistry and Physics of Lipids, 58 (1-2). pp. 175-181. ISSN 0009-3084

Suckling, Colin J. and Tedford, Catriona M. and Proctor, George R. and Khalaf, Abedawn I. and Bence, Laura M. and Stimson, William H. (1991) Catalytic antibodies: a new window on protein chemistry. Ciba Foundation Symposium, 159 (Catal.). pp. 201-210. ISSN 0300-5208