Browse by Author or creator

2024

Alanazi, Ibrahim M. and Alzahrani, Abdullah R. and Alsaad, Mohammad A. and Moqeem, Abdulaziz L. and Hamdi, Abdulmohsen M. and Taher, Mohiuddin M. and Watson, David G. and Grant, M. Helen (2024) The effect of mephedrone on human neuroblastoma and astrocytoma cells. Saudi Pharmaceutical Journal, 32 (4). 102011. ISSN 1319-0164

Jenkinson, Mark R. J. and Meek, Dominic R. M. and Tate, Rothwelle and Brady, Adrian and MacMillan, Sandy and Grant, Helen and Currie, Susan (2024) Cardiac function may be compromised in patients with elevated blood cobalt levels secondary to metal-on-metal hip implants : a pilot study using a novel echocardiography measurement. The Bone & Joint Journal, 106-B (No.3 S). pp. 51-58. ISSN 2049-4394

2023

Alanazi, Ibrahim M. and Alzahrani, Abdullah R. and Zughaibi, Torki A. and Al-Asmari, Ahmed I. and Tabrez, Shams and Henderson, Catherine and Watson, David and Grant, Mary Helen (2023) Metabolomics analysis as a tool to measure cobalt neurotoxicity : an in vitro validation. Metabolites, 13 (6). 698. ISSN 2218-1989

Jenkinson, Mark and Meek, Dominic and MacMillan, Sandy and Tate, Rothwelle and Grant, Mary and Currie, Susan (2023) Cardiac function is compromised in patients with elevated blood cobalt levels secondary to metal-on-metal hip implants. Heart, 109 (Supple). A4. ISSN 1468-201X

Olatunji, Zainab O and MacMillan, Sandy and Cameron-Ruiz, Miren and Bosakhar, Zainab Y and MacKenzie, Graeme and Grant, Mary H and Tate, Rothwelle and MacQuaide, Niall and Currie, Susan (2023) Effects of acute and chronic cobalt treatment on adult rat cardiomyocyte calcium handling. Heart, 109 (Supple). A6. ISSN 1468-201X

2022

Jenkinson, M. R.J. and Meek, R.M.D. and MacMillan, S. and Tate, R. and Grant, M.H. and Currie, S. (2022) Global longitudinal strain is compromised in patients with elevated blood cobalt levels secondary to metal-on-metal hip implants. In: Europhysiology 2022, 2022-09-16 - 2022-09-18, Tivoli Conference Centre.

Gómez-Arnaiz, Sara and Tate, Rothwelle J. and Grant, Mary Helen (2022) Cobalt neurotoxicity : transcriptional effect of elevated cobalt blood levels in the rodent brain. Toxics, 10 (2). 59. ISSN 2305-6304

2021

Jenkinson, Mark R. J. and Meek, Dominic R. M. and Tate, Rothwelle and MacMillan, Sandy and Grant, M. Helen and Currie, Susan (2021) Cobalt-induced cardiomyopathy - do circulating cobalt levels matter? Bone and Joint Research, 10 (6). 340–347. ISSN 2046-3758

2020

Gómez-Arnaiz, S. and Tate, R.J. and Grant, M.H. (2020) Cytotoxicity of cobalt chloride in brain cell lines - a comparison between astrocytoma and neuroblastoma cells. Toxicology in Vitro, 68. 104958. ISSN 0887-2333

2018

Laovitthayanggoon, Sarunya and Henderson, Catherine J. and McCluskey, Claire and Macdonald, Margaret and Tate, Rothwelle J. and Grant, M. Helen and Currie, Susan (2018) Cobalt administration causes reduced contractility with parallel increases in TRPC6 and TRPM7 transporter protein expression in adult rat hearts. Cardiovascular Toxicology. ISSN 1559-0259

2017

Andriakopoulou, C.E. and Zadpoor, A.A. and Grant, M.H. and Riches, P.E. (2017) Development and mechanical characterisation of self-compressed collagen gels. Materials Science and Engineering: C. ISSN 0928-4931

Gomez Arnaiz, Sara and Tate, Rothwelle and Currie, Susan and Grant, Mary (2017) In vitro effects of cobalt ions on CNS derived cell lines. In: British Toxicology Society Congress 2017, 2017-04-03 - 2017-04-05, Hilton Hotel.

Laovitthayanggoon, Sarunya and Henderson, Catherine J. and Tate, Rothwelle J. and Currie, Susan and McCluskey, Claire and Macdonald, Margaret and Grant, M. Helen (2017) In vivo and in vitro toxicity of cobalt in the heart. In: British Toxicology Society Congress 2017, 2017-04-03 - 2017-04-05, Hilton Hotel.

Laovitthayanggoon, Sarunya and Grant, M. Helen and Henderson, Catherine J. and Tate, Rothwelle J. and Currie, Susan (2017) CoCl2 induced cardiotoxicity associated with CoCr alloy orthopaedic implants. Heart, 103 (S2). A4. 9. ISSN 1468-201X

Nelson, Leonard J. and Morgan, Katie and Treskes, Philipp and Samuel, Kay and Henderson, Catherine J. and LeBled, Claire and Homer, Natalie and Grant, M. Helen and Hayes, Peter C. and Plevris, John N. (2017) Human hepatic HepaRG cells maintain an organotypic phenotype with high intrinsic CYP450 activity/metabolism and significantly outperform standard HepG2/C3A cells for pharmaceutical and therapeutic applications. Basic and Clinical Pharmacology and Toxicology, 120 (1). pp. 30-37. ISSN 1742-7835

2016

Alanazi, Ibrahim and Grant, M. Helen and Watson, David and Henderson, Catherine (2016) Comparison of the metabolism of mephedrone in cultured and in freshly isolated primary rat hepatocytes. Applied in Vitro Toxicology, 2 (4). p. 241. ISSN 2332-1539

Khreit, Osama IG and Grant, Helen M and Henderson, Catherine and Watson, David G and Sutcliffe, Oliver B (2016) Identification of novel metabolic pathways of sitagliptin (STG) by LC/MS and LC/MS2 after incubations with rat hepatcoytes. Drug Metabolism and Disposition, 7 (4). 1000220. ISSN 1521-009X

Laovitthayanggoon, Sarunya and Grant, M. Helen and Henderson, Catherine J. and Tate, Rothwelle J. and Currie, Susan (2016) Investigating cobalt toxicity in the context of joint replacement patients - cobalt uptake in primary cardiac fibroblasts and in 3T3 cells. Applied in Vitro Toxicology, 2 (4). ISSN 2332-1539

Irving, Daniel and Lamprou, Dimitrios A. and MacLean, Michelle and MacGregor, Scott J. and Anderson, John G. and Grant, M. Helen (2016) A comparison study of the degradative effects and safety implications of UVC and 405 nm germicidal light sources for endoscope storage. Polymer Degradation and Stability, 133. pp. 249-254. ISSN 0141-3910

Ramakrishnan, P. and MacLean, M. and MacGregor, S. J. and Anderson, J. G. and Grant, M. H. (2016) Development of 405 nm HINS-light technology for decontamination applications in arthroplasty surgery. Bone & Joint Journal : Orthopaedic Proceedings Supplement, 98-B (SUPP 1). p. 22. ISSN 2049-4416

McKenzie, Karen and MacLean, Michelle and Grant, M. Helen and Ramakrishnan, Praveen and MacGregor, Scott J. and Anderson, John G. (2016) The effects of 405 nm light on bacterial membrane integrity determined by salt and bile tolerance assays, leakage of UV absorbing material and SYTOX green labelling. Microbiology, 162 (9). pp. 1680-1688. ISSN 1465-2080

Davidson, Scott and Lamprou, Dimitrios A. and Urquhart, Andrew J. and Grant, M. Helen and Patwardhan, Siddharth V. (2016) Bioinspired silica offers a novel, green and biocompatible alternative to traditional drug delivery systems. ACS Biomaterials Science & Engineering, 2 (9). 1493–1503. ISSN 2373-9878

Ramakrishnan, Praveen and MacLean, Michelle and Anderson, John and MacGregor, Scott and Clarke, Jon and Meek, R.M.D. and Grant, Mary (2016) Considerations for the technical development of 405nm light for decontamination applications in arthroplasty surgery. In: British Orthopaedic Society Conference, 2016-09-05 - 2016-09-06, Glasgow University.

Scott, Fraser and Khalaf, Abedawn and Suckling, Colin and Carter, Katharine and Grant, Mary and Henderson, Catherine and Westrop, Gareth and Watson, David (2016) An evaluation of minor groove binders as anti-lung cancer therapeutics. Bioorganic and Medicinal Chemistry Letters, 26 (15). pp. 3478-3486. ISSN 0960-894X

Ramakrishnan, Praveen and Maclean, Michelle and MacGregor, Scott J. and Anderson, John G. and Grant, M. Helen (2016) Cytotoxic responses to 405 nm light exposure in mammalian and bacterial cells : involvement of reactive oxygen species. Toxicology in Vitro, 33. pp. 54-62. ISSN 0887-2333

Laovitthayanggoon, Sarunya and Tate, Rothwelle and Currie, Susan and Grant, Mary Helen (2016) Cobalt cardiotoxicity - effects on the contractile and non-contractile cells of the heart. FASEB Journal, 30 (1). 178.7. ISSN 0892-6638

2015

Mohd Riduan Bin Mohamad, M and Riches, Philip and Grant, M. Helen (2015) The effects of decellularisation on the mechanical properties of bone, and subsequent recellularisation of the samples. In: American Society for Bone & Mineral Research (ASBMR), 2015-10-09 - 2015-10-12.

Ramakrishnan, P and MacLean, M and MacGregor, S and Anderson, J and Grant, MH (2015) 405 nm light technology shows potential for patient safe decontamination during orthopaedic surgery. European Cells and Materials, 30 (S2). p. 25. ISSN 1473-2262

Davidson, Scott and Grant, Mary and Lamprou, Dimitrios and Patwardhan, Siddharth (2015) Bio-inspired silica nanoparticles as drug delivery vehicles. In: The 42nd Annual Meeting & Exposition of the Controlled Release Society, 2015-07-26 - 2015-07-29, Scotland.

Kemp, Olivia and Grant, Mary and Lamprou, Dimitrios (2015) Microfluidics liposome formulation and investigation of liposome-cell interactions by atomic force microscopy. In: The 42nd Annual Meeting & Exposition of the Controlled Release Society, 2015-07-26 - 2015-07-29, Scotland.

Posada, Olga M. and Tate, Rothwelle J. and Meek, R.M. Dominic and Grant, M. Helen (2015) In vitro analyses of the toxicity, immunological, and gene expression effects of cobalt-chromium alloy wear debris and Co ions derived from metal-on-metal hip implants. Lubricants, 3 (3). pp. 539-568.

Agbekoh, Peter and Henderson, Catherine and Riches, Philip and Grant, Mary (2015) Influence of mechanical properties of collagen on the metabolic activity of sandwich-cultured human hepatocyes. In: 13th European ISSX meeting, 2015-06-22 - 2015-06-25, TIC Building, Strathclyde University.

Omar, Khaled M. K. and Grant, Mary and Henderson, Catherine and Watson, David (2015) LC-MS analysis of the metabolism of the dietary constituent hesperidin by rat hepatocytes. In: 13th European ISSX meeting, 2015-06-22 - 2015-06-25, TIC Building, Strathclyde University.

Alwashih, Mohammad and Watson, David and Grant, Mary and Henderson, Catherine (2015) Metabolomics as a tool to investigate mephadrone as a drug of abuse in rat hepatocytes. In: 13th European ISSX meeting, 2015-06-22 - 2015-06-25, TIC Building, Strathclyde University.

Hobbs, Michael and MacKay, Simon and Grant, Mary and Bloomer, J (2015) Utility of a mechanistic model to investigate the uptake of rosuvastatin in human hepatocytes and time-dependent inhibition of cyclosporine A and cyclosporine AM1. In: 13th European ISSX meeting, 2015-06-22 - 2015-06-25, TIC Building, Strathclyde University.

Posada, Olga M. and Tate, R. J. and Grant, M. H. (2015) Toxicity of cobalt-chromium nanoparticles released from a resurfacing hip implant and cobalt ions on primary human lymphocytes in vitro. Journal of Applied Toxicology, 35 (6). pp. 614-622. ISSN 0260-437X

Posada, Olga M. and Tate, Rothwelle J. and Grant, M. Helen (2015) Effects of CoCr metal wear debris generated from metal-on-metal hip implants and Co ions on human monocyte-like U937 cells. Toxicology in Vitro, 29 (2). pp. 271-280. ISSN 0887-2333

Gupta, Sanjay and MacLean, Michelle and Anderson, John and MacGregor, Scott and Meek, Dominic and Grant, Mary (2015) Inactivation of micro-organisms isolated from infected lower limb arthroplasties using high-intensity narrow-spectrum (HINS) light. The Bone and Joint Journal, 97-B (2). p. 283. ISSN 2049-4394

2014

Omar, Khaled and Grant, M. Helen and Henderson, Catherine and Watson, David George (2014) The complex degradation and metabolism of quercetin in rat hepatocyte incubations. Xenobiotica, 44 (12). pp. 1074-1082. ISSN 0049-8254

Posada, Olga M. and Gilmour, Denise and Tate, Rothwelle J. and Grant, M. Helen (2014) CoCr wear particles generated from CoCr alloy metal-on-metal hip replacements, and cobalt ions stimulate apoptosis and expression of general toxicology-related genes in monocyte-like U937 cells. Toxicology and Applied Pharmacology, 281 (1). 125–135. ISSN 0041-008X

Agbekoh, Peter E. and Henderson, Catherine and Riches, Philip E. and Grant, M. Helen (2014) Effect of cultured rat primary hepatocytes on the mechanical properties of collagen gel matrices. European Cells and Materials, 28 (S.4). p. 77. ISSN 1473-2262

Ramakrishnan, Praveen and MacLean, Michelle and MacGregor, Scott and Anderson, John and Grant, M. Helen (2014) Optimising 405 nm HINS light technology for patient safe decontamination during arthroplasty surgery. European Cells and Materials, 28 (S.4). p. 36. ISSN 1473-2262

Irving, Daniel and Grant, M. Helen and MacLean, Michelle and Lamprou, Dimitrios and MacGregor, Scott and Anderson, John (2014) The degradative effects of germicidal light on flexible endoscope material : the safety and suitability of UVC and 405nm light sources. In: The 9th Healthcare Infection Society International Conference 2014, 2014-11-16 - 2014-11-18, Lyon Convention Centre.

Mohamad, Mohd Riduan and Riches, Philip and Grant, M. Helen (2014) The effects of decellularisation on the mechanical properties of bone. European Cells and Materials, 28 (S.4). p. 72. ISSN 1473-2262

Ramakrishnan, Praveen and MacLean, Michelle and MacGregor, Scott J. and Anderson, John G. and Grant, M. Helen (2014) Differential sensitivity of osteoblasts and bacterial pathogens to 405-nm light highlighting potential for decontamination applications in orthopedic surgery. Journal of Biomedical Optics, 19 (10). 105001. ISSN 1083-3668

Kemp, Olivia and Grant, Helen and Lamprou, Dimitrios (2014) Atomic force microscopy (AFM) analysis of nanocarrier–cell interaction. Toxicology Letters, 229 (Supple). S67. P-1.86. ISSN 0378-4274

Agbekoh, Peter E. and Henderson, Catherine and Riches, Philip E. and Grant, M. Helen (2014) Collagen hydrogel matrices for primary hepatocyte culture. Toxicology Letters, 229 (Supple). S141-S142. P-2.151. ISSN 0378-4274

Ellis, L.C.J. and Grant, M.H. and Hawksworth, G.M. and Weaver, R.J. (2014) Quantification of biliary excretion, sinusoidal excretion and diffusion of 5(6)-carboxy-2',-7'-dichlorofluorescein (CDF) in hepatocytes isolated from Sprague Dawley, Wistar and Mrp2 (TR-) deficient rats. Toxicology in Vitro, 28 (6). 1165–1175. ISSN 0887-2333

Omar, Khaled and Grant, M. Helen and Henderson, Catherine and Watson, David G (2014) The abundant dietary constituent ferulic acid forms a wide range of metabolites including a glutathione adduct when incubated with rat hepatocytes. Xenobiotica, 44 (5). pp. 432-437.

Nelson, L. J. and Treskes, P. and Henderson, C. J. and Homer, N. and Morgan, K. and LeBled, C. and Grant, M. H. and Plevris, J. N. (2014) Human hepatic HepaRG cells maintain high intrinsic CYP450 activity/metabolism and significantly outperform standard HepG2/C3A cells used in drug pharmacology applications. Journal of Hepatology, 60 (1 Supp). S176-S177. ISSN 0168-8278

Steven, Christopher Robert and Busby, Grahame and Mather, C. and Tariq, Balal and Briuglia, Maria Lucia and Lamprou, Dimitrios and Urquhart, Andrew and Grant, Mary and Patwardhan, Siddharth (2014) Bioinspired silica as drug delivery systems and their biocompatibility. Journal of Materials Chemistry B, 2 (31). pp. 5028-5042. ISSN 2050-750X

2013

Posada Estefan, Olga Maria and Grant, Helen and Tate, Rothwelle J. (2013) Co–Cr wear products derived from metal-on-metal articulations induce apoptosis on monocyte-like U937 cells. Toxicology Letters, 28 (Suppl). S75. ISSN 0378-4274

Nelson, L. N. and Grant, H. G. and Henderson, C. H. and Navarro, M. N. and Plevris, J. P. and Treskes, P. T. (2013) Utility of dynamic testosterone profiling for assessing human hepatic culture systems for 3D tissue engineering/pharma applications. International Journal of Artificial Organs, 36 (8). p. 586. ISSN 0391-3988

Busby, Grahame and Riches, Philip and Grant, Mary and MacKay, Simon (2013) The effect of cell ingrowth on the mechanical behaviour of anchored collagen gels. International Journal of Artificial Organs, 36 (8). p. 567. O106. ISSN 0391-3988

Laco, Filip and Grant, Mary and Black, Richard Anthony (2013) Collagen–nanofiber hydrogel composites promote contact guidance of human lymphatic microvascular endothelial cells and directed capillary tube formation. Journal of Biomedical Materials Research Part A, 101A (6). 1787–1799. ISSN 1549-3296

Posada Estefan, Olga Maria and Tate, Rothwelle and Grant, Mary (2013) Co-Cr wear particles and cobalt ions stimulate the expression of human general toxicology related genes on monocyte like U937 cells. In: British Toxicology Society Meeting, 2013-04-07 - 2013-04-10.

McDonald, Richard and Gupta, Sanjay and MacLean, Michelle and Ramakrishnan, Praveen and Anderson, John and MacGregor, Scott and Meek, Dominic and Grant, Mary (2013) 405 nm light exposure of osteoblasts and inactivation of bacterial isolates from arthroplasty patients : potential for new disinfection applications? European Cells and Materials, 25 (March). pp. 204-214. ISSN 1473-2262

Busby, Grahame A. and Grant, M. Helen and MacKay, Simon P. and Riches, Philip E. (2013) Confined compression of collagen hydrogels. Journal of Biomechanics, 46 (4). pp. 837-840. ISSN 0021-9290

Sinclair, J.A. and Henderson, C. and Tettey, J.N.A. and Grant, M.H. (2013) The influence of the choice of digestion enzyme used to prepare rat hepatocytes on xenobiotic uptake and efflux. Toxicology in Vitro, 27 (1). pp. 451-457. ISSN 0887-2333

Khreit, Osama Idris Gibreel and Grant, Mary and Zhang, Tong and Henderson, Catherine and Watson, David and Sutcliffe, Oliver Brook (2013) Elucidation of the phase I and phase II metabolic pathways of (+/-)-4'-nethylmethcathinone (4-MMC) and (+/-)-4'-(trifluoromethyl)methcathinone (4-TFMMC) in rat liver hepatocytes using LC-MS and LC-MS2. Journal of Pharmaceutical and Biomedical Analysis, 72. pp. 177-185. ISSN 1873-264X

2012

Akbar, Moeed and Fraser, Alastair and Graham, GJ and Brewer, James and Grant, Mary (2012) Acute inflammatory response to cobalt chromium orthopaedic wear debris in a rodent air-pouch model. Journal of the Royal Society Interface, 9 (74). pp. 2109-2119. ISSN 1742-5689

Busby, Grahame and Patwardhan, Siddharth and Urquhart, Andrew and Grant, Mary (2012) Understanding the biological safety of silica nanoparticles. In: Britich Toxicology Meeting, 2012-09-10 - 2012-09-11.

Hamilton, C and Henderson, C J and Ulijn, R V and Grant, M H (2012) Galactosylated poly(ethylene glycol) as a scaffold for primary hepatocytes. European Cells and Materials, 23 (Suppl ). p. 30. ISSN 1473-2262

Afolaranmi, Grace and Akbar, Moeed and Brewer, James and Grant, Mary (2012) Distribution of metal released from cobalt–chromium alloy orthopaedic wear particles implanted into air pouches in mice. Journal of Biomedical Materials Research Part A, 100A (6). 1529–1538. ISSN 1549-3296

Dunham, A and Yan, X T and Grant, M H (2012) An investigation of the stiffness moduli of artificial bone materials. European Cells and Materials, 23 (Suppl ). p. 52. ISSN 1473-2262

Griffiths, Sarah and Maclean, Michelle and Anderson, John G. and Macgregor, Scott J. and Grant, H. Mary (2012) Inactivation of microorganisms within collagen gel biomatrices using pulsed electric field treatment. Journal of Materials Science: Materials in Medicine, 23 (2). pp. 507-515. ISSN 0957-4530

Hamilton, Christopher and Henderson, Catherine and Ulijn, Rein and Grant, Mary (2012) Chemically functionalised poly(ethylene) glycol monolayers as scaffolds for primary hepatocytes: cell targeting with galactosamine. In: 3rd Tissue Engineering and Regenerative Medicine World Congress, 2012-07-02.

Wallace, Gillian and Ramsden, Diane and Grant, Mary; Lyubimov, A.V., ed. (2012) General principles of drug disposition. In: Encyclopaedia of Drug Metabolism and Interactions. John Wiley & Sons Inc.. ISBN 9780470921920

Grant, Mary (2012) Metabolic profiling with isolated hepatocytes, and choice of scaffolds for culture. In: Hepatocyte Expert Programme, 2012-03-06 - 2012-03-08. (Unpublished)

Grant, Mary and Henderson, Catherine and Vontivillu Mohanarengan, Subhashree and Phillips, Sion (2012) Primary culture of rat hepatocytes on 3-D glass matrics. In: British Toxicology Society Meeting, 2007-09-01.

Hamilton, Christopher and Henderson, Catherine and Ulijn, Rein and Grant, Mary (2012) Primary cultures of hepatocytes: galactosamine as a ligand of the asialoglycoprotein receptor. In: British Toxicology Society Meeting, 2007-09-01.

2011

Busby, Grahame and Mackay, Simon and Riches, Philip and Grant, Mary (2011) Culture of 3T3 fibroblasts in collagen gels in the presence of ACE inhibitors. Toxicology, 290 (2-3). pp. 135-136. ISSN 0300-483X

Afolaranmi, Grace and Grant, Mary (2011) Effect of ascorbic acid on the distribution of Cr (VI) and CO(II) in the blood and organs of rats. Toxicology, 290 (2-3). p. 120. ISSN 0300-483X

Large, Emma and Pryde, Anne and Plevris, John and Flint, David and Grant, Mary (2011) Insulin-like growth factor binding protein-5 as a biomarker for detection of early liver disease. Toxicology, 290 (2-3). p. 124. ISSN 0300-483X

Afolaranmi, Grace and Al-Mufty, Hassan Heshmat and Grant, Mary (2011) Release of soluble metal ions from copper based dental alloys mesured by ICP-MS. Toxicology, 290 (2-3). p. 119. ISSN 0300-483X

Hamilton, Christopher and Ulijn, Rein Vincent and Grant, Mary (2011) Synthetic scaffolds for the culture of primary hepatocytes: chemically functionalised poly(ethylene glycol) monolayers. In: Surface Science of Biologically Important Interfaces -13, 2011-10-12 - 2011-10-12. (Unpublished)

Large, Emma and Henderson, Catherine and Flint, David and Grant, Mary (2011) IGFBP-5 as a biomarker of de-differentiation in hepatocytes. Toxicology Letters, 205 (Supple). S65-S65. ISSN 0378-4274

Hamilton, Christopher and Ulijn, Rein Vincent and Grant, Mary (2011) Chemically modified scaffolds for the culture of primary hepatocytes. In: The 6th UK and RI Postgraduate Conference in Biomedical Engineering and Medical Physics, 2011-08-14 - 2011-08-16. (Unpublished)

Large, Emma and Henderson, Catherine and Flint, David and Grant, Mary (2011) IGFBP-5 and hepatocyte differentiation. In: 40th Anniversary DMDG Meeting, 2011-08-11 - 2011-08-12. (Unpublished)

Posada Estefan, Olga Maria and Tate, Rothwelle and Grant, Mary (2011) RNA stability in frozen/thawed clinical samples. In: The 6th UK and RI Postgraduate Conference in Biomedical Engineering and Medical Physics, 2011-08-14 - 2011-08-16.

Dunham, April and Yan, Xiu and Grant, Mary (2011) An investigation into the compatibility of 5 potential binders for the production of artificial bone scaffolds. In: The 6th UK and RI Postgraduate Conference in Biomedical Engineering and Medical Physics, 2011-08-14 - 2011-08-16. (Unpublished)

Busby, Grahame and Riches, Philip and Mackay, Simon and Grant, Mary (2011) A novel method of characterising mechanical properties of hydrogels. European Cells and Materials, 22 (3). p. 70. ISSN 1473-2262

Mcdonald, Richard and Maclean, Michelle and Anderson, John and Macgregor, Scott and Grant, Mary (2011) Effect of 405 nm high-intensity narrow-spectrum light on osteoblast function. In: XII eCells & Materials Conference on Implant Infection, 2011-06-23 - 2011-06-25.

Akbar, Moeed and Brewer, James M. and Grant, M. Helen (2011) The effect of chromium and cobalt ions on primary human lymphocytes in vitro. Journal of Immunotoxicology, 8 (2). pp. 140-149.

Busby, Grahame and Riches, Philip and Mackay, Simon and Grant, Mary (2011) Compression testing of collagen hydrogels. In: BOSE Electroforce Systems UK User Group Meeting, 2011-04-06 - 2011-04-06. (Unpublished)

Mcdonald, Richard and Grant, M. Helen and Macgregor, Scott J. and Anderson, John G. and Maclean, Michelle (2011) Effect of 405 nm high-intensity narrow-spectrum light on fibroblast populated collagen lattices : an in vitro model of wound healing. Journal of Biomedical Optics, 16 (4). 048003. ISSN 1083-3668

Laco, F. and Grant, M.H. and Flint, D.J. and Black, R.A. (2011) Cellular trans-differentiation and morphogenesis towards the lymphatic lineage in regenerative medicine. Stem Cells and Development, 20 (2). pp. 181-195. ISSN 1547-3287

Griffiths, Sarah and Maclean, Michelle and MacGregor, Scott J. and Anderson, John G. and Grant, M. Helen (2011) Decontamination of collagen biomatrices with combined pulsed electric field and nisin treatment. Journal of Biomedical Materials Research Part B: Applied Biomaterials, 96B (2). pp. 287-293.

Afolaranmi, Grace A. and Henderson, Catherine and Grant, M.Helen (2011) Effect of Chromium and Cobalt ions on phase I and phase II enzymatic activities in vitro in freshly isolated rat hepatocytes. Toxicology in Vitro, 25 (1). pp. 125-130. ISSN 0887-2333

George, Susan M. and Gaylor, John D.S. and Leadbitter, Jason and Grant, M.Helen (2011) The effect of beta-cyclodextrin and hydroxypropyl beta-cyclodextrin incorporation into plasticised poly(vinyl chloride) on its compatibility with human monocytes. Journal of Biomedical Materials Research Part B: Applied Biomaterials, 96B (2). pp. 310-315.

Gupta, Sanjay and Maclean, Michelle and Anderson, John and Macgregor, Scott and Meek, Dominic and Grant, Mary (2011) Inactivation of microorganisms isolated from infected arthroplasty using high intensity narrow spectrum (HINS) light. In: British Orthopaedic Association BOA/IOA Combined Meeting, 2011-09-01.

Posada Estefan, Olga Maria and Tate, Rothwelle and Grant, Mary (2011) RNA stability in frozen/thawed clinical blood samples. In: British Toxicology Society Meeting, 2011-09-05 - 2011-09-06.

Afolaranmi, Grace and Grant, Mary (2011) The distribution of soluble Cr and Co ions in the blood and organs of rats and the effect of ascorbic acid on the distribution. Journal of Applied Toxicology, 31 (7).

Dunham, April and Yan, Xiu and Grant, Mary (2011) An investigation into the compatibility of 5 potential binders for the production of artificial bone scaffolds. In: British Toxicology Society Meeting, 2011-09-05 - 2011-09-06.

2010

Large, E. and Henderson, C.J. and Flint, D.J. and Grant, M.H. (2010) Oxidative stress via hydrogen peroxide and menadione does not induce the secretion of IGFBP-5 in primary rat hepatocytes. Toxicology, 278 (3). pp. 356-357. ISSN 0300-483X

Akbar, M. and Brewer, J.M. and Grant, M.H. (2010) Inflammatory response to orthopaedic cobalt chromium alloy wear debris in a rodent air pouch model. Toxicology Letters, 196S. S199. ISSN 0378-4274

Raghunathan, Vijay Krishna and Grant, M.H. and Ellis, E. (2010) Changes in protein expression associated with chronic in vitro exposure of hexavalent chromium to osteoblasts and monocytes: a proteomic approach. Journal of Biomedical Materials Research Part A, 92A (2). pp. 615-625. ISSN 1549-3296

Laco, F. and Grant, M.H. and Flint, D.J. and Black, R.A. (2010) Electrospun 3D Scaffolds for Lymphatic Tissue Engineering. In: Gordon Research Conference for Molecular Mechanisms in Lymphatic Function & Disease, 2010-06-13 - 2010-06-18.

Akbar, M. and Brewer, J.M. and Grant, M.H. (2010) Interaction of metal ions with human lymphocytes. In: 12th Meeting of the Combined Orthopaedic Associations, 1900-01-01.

Afolaranmi, G. and Tettey, J.N.A. and Murray, H.M. and Meek, R.M.D. and Grant, M.H. (2010) The effect of anticoagulants on the distribution of chromium VI in blood fractions relevance to patients with metal orthopedic implants. Journal of Arthroplasty, 25 (1). pp. 118-120. ISSN 1532-8406

McDonald, R. and MacGregor, S.J. and Maclean, M. and Anderson, J.G. and Grant, M.H. (2010) The effect of high-intensity narrow spectrum light on osteoblast function. In: UK Biomaterials Society, 2010-07-01.

Busby, G. and Riches, P.E. and Mackay, S.P. and Grant, M.H. (2010) A novel method of characterising mechanical properties of collagen based scaffolds for tissue engineering. In: UK Biomaterials Society, 2010-07-01.

2009

Akbar, M. and Brewer, J.M. and Grant, M.H. (2009) Chromium and cobalt ions cause apoptosis in human lymphocytes in vitro. In: British Toxicology Annual Meeting, 2009-09-06 - 2009-09-07. (Unpublished)

Smith, Sharon and Griffiths, S. and MacGregor, Scott and Beveridge, Joe and Anderson, John and van der Walle, Christopher F. and Grant, M.H. (2009) Pulsed electric field as a potential new method for microbial inactivation in scaffold materials for tissue engineering : the effect on collagen as a scaffold. Journal of Biomedical Materials Research Part A, 90A (3). pp. 844-851. ISSN 1549-3296

MacGregor, S.J. and Anderson, J.G. and Woolsey, G. and Grant, M. and Beveridge, J.R. and Griffiths, S. and Smith, S.L. and Murdoch, L.E. and Timoshkin, I. (2009) Development and applications in electronic sterilisation technologies. In: 17th International Conference on Gas Discharges and Their Applications, 1900-01-01.

Afolaranmi, G.A. and Tettey, J.N.A. and Murray, H.M. and Meek, R.M.D. and Farmer, J. and Eades, L.J. and Grant, M.H. (2009) Blood chromium and cobalt levels after Durom hip resurfacing. In: British Orthopaedic Research Society Annual Meeting, 2009-06-22 - 2009-06-23. (Unpublished)

Raghunathan, Vijay Krishna and Ellis, E. and Grant, M. Helen (2009) Response to chronic exposure to hexavalent chromium in human monocytes. Toxicology in Vitro, 23 (4). pp. 647-652. ISSN 0887-2333

Sinclair, J.A. and Henderson, C.J. and Martin, I.K. and Grant, M.H. and Tettey, J.N.A. (2009) The extent of phase I and phase II reactions is affected by the choice of enzyme used to prepare rat hepatocytes. Chemico-Biological Interactions, 179 (2-3). pp. 256-262. ISSN 0009-2797

Thi, M.D. and Grant, M.H. and Mullen, Alexander B. and Tettey, J.N.A. and Mackay, S.P. and Clark, Rachael L. (2009) Metabolism of two new benzodiazepine-type anti-leishmanial agents in rat hepatocytes and hepatic microsomes and their interaction with glutathione in macrophages. Journal of Pharmacy and Pharmacology, 61 (3). pp. 399-406. ISSN 0022-3573

Raghunathan, V.K. and Tettey, J.N.A. and Ellis, E.M. and Grant, M.H. (2009) Comparative chronic in vitro toxicity of hexavalent chromium to osteoblasts and monocytes. Journal of Biomedical Materials Research Part A, 88A (2). pp. 543-550. ISSN 1549-3296

Griffiths, S. and Maclean, M. and MacGregor, S.J. and Anderson, J.G. and Grant, M.H. (2009) Combined treatment of biomatrices with nisin and pulsed electric fields as a potential decontamination method? European Cells and Materials, 18 (Suppl.). p. 18. ISSN 1473-2262

McDonald, R. and MacGregor, S.J. and Maclean, M. and Anderson, J.G. and Grant, M.H. (2009) Effect of HINS light on the contraction of fibroblast populated collagen lattices. European Cells and Materials, 18 (Suppl.). p. 79. ISSN 1473-2262

Ho, B. and Barbenel, J.C. and Grant, M.H. (2009) Effect of low-level laser treatment of tissue-engineered skin substitutes: contraction of collagen lattices. Journal of Biomedical Optics, 14 (3). 034002. ISSN 1083-3668

Smith, S. and Maclean, M. and MacGregor, S.J. and Anderson, J.G. and Grant, M.H. (2009) Impact of varying intensities of blue-light exposure on 3T3 cells. European Cells and Materials, 18 (Suppl.). p. 106. ISSN 1473-2262

Griffiths, S. and MacGregor, S.J. and Anderson, J.G. and Maclean, M. and Gaylor, J.D.S. and Grant, M.H.; Teck Lim, Chewee and Goh, James C.H., eds. (2009) Inactivation of problematic micro-organisms in collagen based media by pulsed electrical field treatment (PEF). In: Proceedings of the 13th International Conference on Biomedical Engineering. IFMBE Proceedings, 23 (Track ). Springer Berlin Heidelberg, pp. 1320-1324. ISBN 978-3-540-92840-9

Saddiq, Z.A. and Barbenel, J.C. and Grant, M.H. (2009) The mechanical strength of collagen gels containing glycosaminoglycans and populated with fibroblasts. Journal of Biomedical Materials Research Part A, 89A (3). pp. 679-706. ISSN 1549-3296

2008

Kadi, A.A. and El-Kashef, H.A. and Abdel-Aziz, A.A.M. and Hassan, G. and Tettey, J.N.A. and Grant, M.H. and Lehmann, J. and El-Subbagh, H.I. (2008) Synthesis, ultra-short acting hypnotic activity, and metabolic profile of ethyl 8-oxo-5,6,7,8-tetrahydro-thiazolo[3,2-a] [1,3]diazepin-3-carboxylate (HIE-124). ChemInform, 39 (22). ISSN 1522-2667

Griffiths, S. and Smith, S. and MacGregor, S.J. and Anderson, J.G. and van der Walle, Christopher F. and Beveridge, J.R. and Grant, Helen (2008) Pulsed electric field treatment as a potential method for microbial inactivation in scaffold materials for tissue engineering: the inactivation of bacteria in collagen gel. Journal of Applied Microbiology, 105 (4). pp. 963-969.

Kadi, A.A. and Ei-Kashef, H.A. and Abdel-Aziz, A.A.M. and Hassan, G.S. and Tettey, J.N.A. and Grant, M.H. and Lehmann, J. and EI-Subbagh, H.I. (2008) Synthesis, Ultra-Short Acting Hypnotic Activity, and Metabolic Profile of Ethyl 8-Oxo-5,6,7,8-tetrahydro-thiazolo[3,2-a] [1,3]diazepin-3-carboxylate (HIE-124). Archiv der Pharmazie, 341 (2). pp. 81-89. ISSN 0365-6233

Gunaratnam, M. and Grant, M.H. (2008) Cr(VI) inhibits DNA, RNA and protein syntheses in hepatocytes: Involvement of glutathione reductase, reduced glutathione and DT-diaphorase. Toxicology in Vitro, 22 (4). pp. 879-886. ISSN 0887-2333

Smith, S. and Maclean, M. and MacGregor, S.J. and Anderson, J.G. and Grant, M.H.; (2008) Exposure of 3T3 mouse fibroblasts and collagen to high intensity blue light. In: Proceedings of the 13th International Conference on Biomedical Engineering. IFMBE Proceedings, 23 (Track ). Springer, pp. 1352-1355. ISBN 978-3-540-92840-9

Clayton, R.A.E. and Beggs, I. and Salter, D.M. and Grant, M.H. and Patton, J.T. and Porter, D.E. (2008) Inflammatory pseudotumor associated with femoral nerve palsy following metal-on-metal resurfacing of the hip. Journal of Bone and Joint Surgery, American Volume, 90A (9). pp. 1988-1993.

Akbar, M. and Henderson, C.J. and Grant, M. Helen (2008) Inhibition of cell growth and glutathione depletion by calcium channel blockers. Toxicology, 253 (1-3). pp. 14-15. ISSN 0300-483X

Sinclair, J.A. and Henderson, C.J. and Martin, I.J. and Grant, M.H. and Tettey, J.N.A. (2008) MRP2 transport function in rat hepatocytes and the effect of the liver digestion enzyme. Drug Metabolism Reviews, 40 (Supple). p. 100. ISSN 0360-2532

Smith, S. and Griffiths, S. and MacGregor, S.J. and Anderson, J.G. and van der Walle, Christopher F. and Grant, M.H. (2008) Pulsed electric field (PEF) treatment: A novel decontamination method for tissue engineering matrices. In: UK Society for Biomaterials Meeting, 2008-06-01.

Afolaranmi, G.A. and Tettey, J.N.A. and Meek, R.M.D. and Grant, M.H. (2008) Release of chromium from orthpaedic arthroplasties. Open Orthopaedics Journal, 2 (9). pp. 10-18. ISSN 1874-3250

Sinclair, J.A. and Henderson, C.J. and Martin, I.K. and Grant, M.H. and Tettey, J.N.A. (2008) Trypsin inhibitor may increase the formation of GSH conjugates of potentially toxic reactive intermediates in isolated rat hepatocytes. Journal of Pharmacy and Pharmacology, 60 (59). A24-A25. ISSN 0022-3573

Raghunathan, V.K. and Tettey, J.N.A. and Grant, M.H. (2008) Uptake of Cr (VI) and Cr (III)-GSH complex across rat liver cell nuclei. Toxicology, 253 (1-3). pp. 20-21. ISSN 0300-483X

Afolaranmi, G.A. and Tettey, J.N.A. and Gaylor, J.D.S. and Murray, H.M. and Meek, R.M.D. and Grant, M.H. (2008) Uptake of chromium into red blood cells does not affect the ability of haemoglobin to bind oxygen. Toxicology, 253 (1-3). pp. 15-16. ISSN 0300-483X

2007

Lalaouni, A. and Henderson, C.J. and Kupper, C. and Grant, M.H. (2007) The interaction of chromium (VI) with macrophages : Depletion of glutathione and inhibition of glutathione reductase. Toxicology, 236 (1-2). pp. 76-81. ISSN 0300-483X

Duong Thi, M.D. and Clarke, R. and Mackay, S.P. and Mullen, A.B. and Tettey, J.N.A. and Grant, M.H. (2007) Metabolism and toxicity of two new benzodiazepine-type antileishmanial agents in hepatocytes and macrophages. Toxicology, 231 (2-3). pp. 104-105. ISSN 0300-483X

Raghunathan, Vijay Krishna and Ellis, Elizabeth M. and Tettey, Justice N.A. and Grant, M. Helen (2007) Involvement of reduced glutathione and glutathione reductase in the chronic toxicity of hexavalent chromium to monocytes in vitro. Toxicology, 231 (2-3). pp. 105-106. ISSN 0300-483X

Clark, Rachael L. and Carter, Katharine C. and Mullen, Alexander B. and Coxon, Geoffrey D. and Owusu-Dapaah, George and McFarlane, Emma and Dao Duong Thi, M. and Grant, M.H. and Tettey, J.N.A. and Mackay, Simon P. (2007) Identification of the benzodiazepines as a new class of antileishmanial agent. Bioorganic and Medicinal Chemistry Letters, 17 (3). pp. 624-627. ISSN 0960-894X

Ibrahim, H. and El-Sabbagh, N.M. and Changtam, C. and Gould, M. and Grant, M.H. and Tettey, J.N.A. and Vance, S. and Cooper, A. and Suksamrarn, A. and De Koning, H.P. (2007) Analogues of curcumin as a new class of antiprotozoals. In: Medicinal Chemistry in Parasitology: new avenues in, 2007-02-01.

Raghunathan, Vijay Krishna and Tettey, J.N.A. and Ellis, E. and Grant, M.H. (2007) Changes in antioxidant enzymes during chronic in vitro exposure to chromium. In: British Toxicology Society Meeting, 2007-09-01.

Sinclair, J.A. and Henderson, C.J. and Martin, I.J. and Grant, M.H. and Tettey, J.N.A. (2007) Collagenase - alone or in combination for the preparation of hepatocytes? The effect on phase 1 and phase 2 biotransformations. Journal of Pharmacy and Pharmacology, 59 (S1). A16. ISSN 0022-3573

Smith, S. and Griffiths, S. and Grant, M.H. and MacGregor, S.J. and Anderson, J.G. (2007) Pulsed electric field (PEF) treatment as a sterilisation method for collagen based biomatrices. Journal of Pharmacy and Pharmacology, 59 (Supple). A64-A64. ISSN 0022-3573

Stevenson, D. and Morgan, C. and McLellan, L.A. and Grant, M.H. (2007) Reduced glutathione levels and expression of the enzymes of glutathione synthesis in cryopreserved hepatocyte monolayer cultures. Toxicology, 231 (2-3). pp. 100-101. ISSN 0300-483X

Stevenson, D.J. and Morgan, C. and McLellan, L.I. and Grant, M.H. (2007) Reduced glutathione levels and expression of the enzymes of glutathione synthesis in cryopreserved hepatocyte monolayer cultures. Toxicology in Vitro, 21 (3). pp. 527-532. ISSN 0887-2333

Boibessot, I. and Tettey, J.N.A. and Skellern, G.G. and Grant, M.H. (2007) Toxicity of phenanthridine trypanocides in primary cultures of hepatocytes: Interaction with reduced glutathione. In: British Toxicology Society Meeting, 2007-09-01.

Griffiths, S. and Smith, S. and Grant, M.H. and MacGregor, S.J. and Anderson, J.G. (2007) The application of pulsed electric fields to eliminate escherichia coli from collagen based biomatrices. In: Society for General Microbiology 161st Meeting, 2007-09-03 - 2007-09-06.

Sinclair, J.A. and Henderson, C.J. and Martin, I.K. and Grant, M.H. and Tettey, J.N.A. (2007) The digestion enzyme used in isolation procedures influences metabolic capacity of hepatocytes. In: Life Sciences 2007, 2007-07-09 - 2007-07-10, SECC.

Afolaranmi, G.A. and Tettey, J.N.A. and Murray, H. and Meek, R.M.D. and Grant, M.H. (2007) The effect of anticoagulants on the distribution of chromium (VI) in blood fractions. Journal of Pharmacy and Pharmacology, 59 (S1). A4. ISSN 0022-3573

Afolaranmi, G.A. and Tettey, J.N.A. and Gaylor, J.D.S. and Murray, H.M. and Meek, R.M.D. and Grant, M.H. (2007) The effect of chromium on the oxygen uptake capacity of blood. In: Life Sciences 2007, 2007-07-09 - 2007-07-10, SECC.

2006

Boibessot, I. and Tettey, J.N.A. and Skellern, G.G. and Watson, D.G. and Grant, M.H. (2006) The metabolism of isometamidium in hepatocytes from control and inducer treated rats. Journal of Veterinary Pharmacology and Therapeutics, 29 (6). pp. 547-553. ISSN 0140-7783

Meechan, A.J. and Henderson, C. and Bates, Catharine D. and Grant, M.H. and Tettey, J.N.A. (2006) Metabolism of troglitazone in hepatocytes isolated from experimentally induced diabetic rats. Journal of Pharmacy and Pharmacology, 58 (10). pp. 1359-1365. ISSN 0022-3573

Raghunathan, V.K. and Ellis, E.M. and Grant, M.H. (2006) Chronic toxicity of hexavalent chromium to U937 human monocyte cell line. In: BioScience 2006: Bioscience in the 21st Century, 2006-07-23 - 2006-07-27.

George, S.M. and Gaylor, J.D.S. and Leadbitter, J. and Grant, M.H. (2006) Evaluation of toxicity of modified PVC materials using a human monocyte cell line. In: BioScience 2006: Bioscience in the 21st Century, 2006-07-23 - 2006-07-27.

Raghunathan, Vijay Krishna and Duffin, B. and Oladokun, G. and Ellis, E. and Tettey, J.N.A. and Meek, R.M.D. and Murray, H.M. and Grant, M.H. (2006) Osteoblast and monocyte function after chronic exposure to metal ions. In: Proceedings of the Meeting on Biological Implications of Metal-on-Metal Articulations, 2006-11-01.

Sinclair, J.A. and Henderson, C.J. and Grant, M.H. and Martin, I.J. and Tettey, J.N.A. (2006) The influence of digestion enzymes on the metabolic stability of rat hepatocytes. In: Drug Metabolism Discussion Group Meeting, 2006-04-27 - 2006-04-28.

George, S.M. and Gaylor, J.D.S. and Leadbitter, J. and Grant, M.H. (2006) The interaction of plasticised PVC materials with u937 human monocyte cell line and human platelets. In: 26th Meeting of the European Biomaterials Society, 1900-01-01.

Brodie, J.C. and Merry, J. and Grant, M.H. (2006) The mechanical properties of calcium phosphate ceramics modified by collagen coating and populated by osteoblasts. Journal of Materials Science: Materials in Medicine, 17 (1). pp. 43-48. ISSN 0957-4530

2005

Ganguli, A. and Lloyd, A.W. and Steward, C. and Butler, S. and Philips, G. and Meikle, S.T. and Grant, M.H. (2005) Bacterial adhesion on bisphosphonate coated hydroxyapatite. Journal of Materials Science: Materials in Medicine, 16 (4). pp. 283-287. ISSN 0957-4530

Stevenson, D.J. and Grant, M.H.; (2005) Cryopreservation of hepatocytes for bioartificial liver devices. In: Bioreactors for Tissue Engineering: Principles, Design and Operation. Springer, Dordrecht, Netherlands, pp. 353-372. ISBN 978-1-4020-3740-5

Kataropoulou, M. and Henderson, C.J. and Grant, M.H. (2005) Metabolic studies of hepatocytes cultured on collagen substrates modified to contain glycosaminoglycans. Tissue Engineering, 11 (7-8). pp. 1263-1273. ISSN 1076-3279

Brodie, J.C. and Goldie, E.I. and Connel, G. and Merry, J. and Grant, M.H. (2005) Osteoblast interactions with calcium phosphate ceramics modified by coating with type I collagen. Journal of Biomedical Materials Research, 73A (4). pp. 409-421. ISSN 0021-9304

Saddiq, Z.A. and Barbenel, J.C. and Grant, M.H. (2005) The mechanical strength of collagen gels containing glycosaminoglycans and populated with fibroblasts. In: Tissue and Cell Engineering Society Meeting, 2005-05-20 - 2005-05-22.

Grant, M.H. and Morgan, C. and Henderson, C.J. and Malsch, G. and Seifert, B. and Albrecht, W. and Groth, T. (2005) The viability and function of primary rat hepatocytes cultured on polymeric membranes developed for hybrid artificial liver devices. Journal of Biomedical Materials Research, 73A (3). pp. 367-375. ISSN 0021-9304

2004

Winn, P.L. and Kelso, K. and Grant, M.H. (2004) Inhibition of cell growth by lovastatin. Toxicology, 202 (1-2). pp. 106-107. ISSN 0300-483X

Winn, P.L. and Kelso, K. and Grant, M.H. (2004) The effects of glycerol trinitrate, lovastatin and aspirin on the proliferation of human aortic smooth muscle cells. Toxicology, 194 (3). pp. 241-242. ISSN 0300-483X

Winn, P.L. and Wallace, H.M. and Clarke, Brendan and Kelso, K. and Grant, M.H. (2004) Aspirin and glyceryl trinitrate effects on polyamine uptake and smooth muscle cell growth. In: UNSPECIFIED.

Stevenson, D.J. and Morgan, C. and Goldie, E. and Connel, G. and Grant, M.H. (2004) Cryopreservation of viable hepatocyte monolayers in cryoprotectant media with high serum content: metabolism of testosterone and kaempherol post-cryopreservation. Cryobiology, 49 (2). pp. 97-113. ISSN 0011-2240

Ting, L.K.S. and Wang, N. and Grant, M.H. and Henderson, C.J. (2004) Culture of rodent hepatocytes on microgrooved surfaces: application for a flat-plate bioartificial liver device. In: 1st International Bioengineering Conference 2004, Bioengineering: Challenges and Innovations, 2004-09-08 - 2004-09-10.

Gunaratnam, M. and Grant, M.H. (2004) Damage to F-actin and cell death induced by chromium VI and nickel in primary monolayer cultures of rat hepatocytes. Toxicology in Vitro, 18 (3). pp. 245-253. ISSN 0887-2333

Meechan, A.J. and Henderson, C.J. and Coxon, Geoff and Tettey, J.N.A. and Grant, M.H. (2004) Evaluation of the toxicity of a substituted 2,4-thiazolidinedione moiety to isolated rat hepatocytes : relevance to glitazone toxicity. pA2 Online: E Journal of the British Pharmacological Society, 2 (4).

Bibi, S. and Angeli, F. and Grant, M.H.; (2004) Inhibition of glutathione reductase by chromium (VI). In: Proceedings of the British Pharmacological Society Conference 2004. British Pharmacological Society.

Grant, M.H. and Spence, W.D. (2004) Long-term monitoring of activity in the below knee amputee. In: American Academy of Orthotists and Prosthetists Annual Meeting, 2004-02-24 - 2004-02-27.

Rukavina, M. and Winn, P.L. and Grant, M.H. (2004) Lovastatin inhibits macrophage proliferation but stimulates phagocytosis. In: CELSUS Meeting, 1900-01-01.

Ho, Gideon and Henderson, Catherine J. and Barbenel, Joseph C. and Grant, M.H. (2004) Low level laser therapy and tissue engineered skin substitutes: effect on the proliferation rate of 3T3 mouse fibroblast cells. Proceedings of SPIE: The International Society for Optical Engineering, 5610 (124).

Bohlooli, S. and Mahmoudian, M. and Skellern, G.G. and Grant, M.H. and Tettey, J.N.A. (2004) Metabolism of the novel dihydropyridine calcium channel blockers mebudipine and dibudipine by isolated rat hepatocytes. Journal of Pharmacy and Pharmacology, 56. pp. 1469-1475. ISSN 0022-3573

Stevenson, D.J. and Morgan, C. and Grant, M.H. (2004) Mitochondrial function in hepatocyte monolayer cultures. Toxicology, 202 (1-2). pp. 101-102. ISSN 0300-483X

Atsriku, C. and Grant, M.H. and Skellern, G.G. and Watson, D.G. (2004) The effects of inducing agents on the metabolism of pentamidine by isolated rat hepatocytes. Toxicology, 194 (3). pp. 234-235. ISSN 0300-483X

Ball, A.J. and Tettey, J.N.A. and Grant, M.H. (2004) The toxicity of troglitazone, roziglitazone and vitamin e in human hep g2 hepatoma cells. Toxicology, 194 (3). pp. 250-251. ISSN 0300-483X

2003

Ho, G. and Barbenel, J.C. and Grant, M.H. (2003) The effect of low level laser therapy on the contraction of fibroblast populated collagen-GAG lattices in vitro. Tissue Engineering, 9 (4). p. 805. ISSN 1076-3279

Stevenson, D.J. and Morgan, C. and Goldie, E.I. and Connel, G. and Grant, M.H. (2003) Cryopreservation of hepatocyte monolayers. In: Hepatocyte Users Group Meeting, 2003-03-28 - 2003-03-29.

Stevenson, D.J. and Morgan, C. and Goldie, E.I. and Connel, G. and Grant, M.H. (2003) Cryopreservation, hepatocyte monolayers and DMSO shock. In: Cryomed Biol Meeting, 2003-09-01.

Ho, G. and Grant, M.H. and Barbenel, J.C. and Henderson, C.J. (2003) Low level laser therapy on artificial skin substitutes : no significant effect on the proliferation rate of 3T3 mouse fibroblast cells. Lasers in Medical Science, 18. S14-S15. ISSN 0268-8921

Atsriku, C. and Skellern, G.G. and Grant, M.H. and Watson, D.G. (2003) The effect of inducing agents on the metabolism of trypanocidal diamidines by isolated rat hepatocytes. Chemico-Biological Interactions, 146 (3). pp. 297-305. ISSN 0009-2797

Kataropoulou, M. and Henderson, C.J. and Grant, M.H. (2003) The influence of glycosaminoglycans and cross-linking agents on the phenotype of hepatocytes cultured on collagen gels. Human and Experimental Toxicology, 22 (2). pp. 65-71. ISSN 0960-3271

Jairaj, Mark and Watson, D.G. and Grant, M. Helen and Skellern, G.G. (2003) The toxicity of opiates and their metabolites in HepG2 cells. Chemico-Biological Interactions, 146 (2). pp. 121-129. ISSN 0009-2797

2002

Gunaratnam, M. and Grant, M.H.; (2002) Chromium VI induced cytoskeletal damage and cell death in isolated hepatocytes. In: Biochemical Society Transactions. Biochemical Society, pp. 748-750.

Jairaj, M. and Watson, D.G. and Grant, M.H. and Skellern, G.G. (2002) Metabolic profiling of the antitussive drug pholcodine in rat hepatocytes. In: Gordon Research Conference on Drug Metabolism, 2002-07-14 - 2002-07-19.

Atsriku, C. and Watson, D.G. and Grant, M.H. and Skellern, G.G. (2002) The application of liquid chromatography-tandem mass spectrometry to in vitro metabolic studies of pentamidine by induced isolated rat hepatocytes. In: 50th Meeting of the American Society for Mass Spectrometry, 2002-06-02 - 2002-06-06.

Grant, M.H. (2002) Bioartificial liver devices. In: 11th Annual Conference of the British Society for Histocompatibility and Immunogenetics, 1900-01-01.

Gunaratnam, M. and Grant, M.H. (2002) Chromium VI induced damage to the cytoskeleton and cell death in isolated hepatocytes. Biochemical Society Transactions, 30. pp. 748-750. ISSN 0300-5127

Jairaj, M. and Watson, D.G. and Grant, M.H. and Skellern, G.G. (2002) Comparative biotransformation of morphine, codeine and pholcodine in rat hepatocytes: identification of a novel metabolite of pholcodine. Xenobiotica, 32 (12). pp. 979-986. ISSN 0049-8254

Kataropoulou, M. and Goldie, E. and Connel, G. and Grant, M.H. (2002) Confocal laser scanning microscopy (CLSM) study of hepatocytes cultured on collagen films and gels. European Cells and Materials, 4 (2). pp. 72-73. ISSN 1473-2262

Ho, G. and Grant, M.H. and Barbenel, J.C. (2002) Contractile behaviour of 3T3 mouse fibroblasts in artificial skin substitutes: effect of different cell-seeding methods. European Cells and Materials, 4 (2). pp. 55-56. ISSN 1473-2262

Stevenson, D.J. and Grant, M.H. and Goldie, E.I. and Connel, G. and Morgan, C. (2002) Cryopreservation of hepatocytes: the monolayer approach. In: RSC-DMG 2002: New Technologies in Drug Discovery, 2002-12-12 - 2002-12-13.

McKay, G.C. and Henderson, C.J. and Goldie, E.I. and Connel, G. and Westmoreland, C. and Grant, M.H. (2002) Cryopreservation of rat hepatocyte monolayers: cell viability and cytochrome P450 content in post-thaw cultures. Toxicology in Vitro, 16 (1). pp. 71-79. ISSN 0887-2333

Stevenson, D. and Morgan, C. and Goldie, E.I. and Connel, G. and Grant, M.H. (2002) Cryopreserved hepatocyte monolayers. Biochemical Society Transactions, 30. p. 94. ISSN 0300-5127

Atsriku, C. and Watson, D.G. and Tettey, J.N.A. and Grant, M.H. and Skellern, G.G. (2002) Determination of diminazene aceturate in pharmaceutical formulations by HPLC and identification of related substances by lC/MS. Journal of Pharmaceutical and Biomedical Analysis, 30 (4). pp. 979-986. ISSN 1873-264X

Kataropoulou, M. and Henderson, C.J. and Grant, M.H. (2002) Expression of glutathione-S-transferases in hepatocytes cultured on collagen gels of different composition. Toxicology, 192. pp. 87-88. ISSN 0300-483X

Ball, A.J. and Rodgers, E.H. and Goldie, E.I. and Connel, G. and Savage, R. and Hamblin, J. and Grant, M.H. (2002) Growth and viability of osteoblasts on hydroxyapatite and tri-calcium phosphate ceramics: the effect of collagen coating. European Cells and Materials, 4 (2). p. 57. ISSN 1473-2262

Kataropoulou, M. and Henderson, C.J. and Grant, M.H. (2002) Kaempferol metabolism by rat hepatocytes cultured on different collagen substrates. Biochemical Society Transactions, 30. p. 94. ISSN 0300-5127

Stevenson, D. and Wokosin, D. and Girkin, J. and Grant, M.H. (2002) Measurement of the intracellular distribution of reduced glutathione in cultured rat hepatocytes using monochlorobimane and confocal laser scanning microscopy. Toxicology in Vitro, 16 (5). pp. 609-619. ISSN 0887-2333

Boibessot, I. and Grant, M.H. and Turner, M.C.J. and Skellern, G.G. and Watson, D.G. and Goldie, E.I. and Connel, G. and Macintosh, A. (2002) Metabolism and distribution of phenanthridine trypanocides in trypanosome Brucei brucei. Acta Tropica, 84 (3). pp. 219-228. ISSN 0001-706X

Oliveira, E.D.J. and Watson, D.G. and Grant, M.H. (2002) Metabolism of quercetin and kaempferol by rat hepatocytes and identification of flavonoid glycosides in plasma. Xenobiotica, 32 (4). pp. 279-287. ISSN 0049-8254

Connolly, P. and Grant, M.H. and Smith, A.C.J. and Stevenson, D. (2002) Monitoring and storing tissue for regenerative medicine. In: Regenerative Medicine European Strategy Meeting, 1900-01-01.

Ganguli, A. and Lloyd, A.W. and Steward, C. and Butler, S.H. and Philips, G. and Meikle, S.T. and Grant, M.H. (2002) Osteoblast growth and bacterial adhesion on bisphosphonate coated hydroxyapatite. In: Institute of Physics and Engineering in Medicine 27th Annual Day Conference on 'Biomechanical, Biological and Biomaterials Interactions at Interfaces with Implants', 2002-09-10 - 2002-09-12.

Gunaratnam, M. and Pohlscheidt, M. and Grant, M.H. (2002) Pretreatment of rats with the inducing agents phenobarbitone and 3-methylcholanthrene ameliorates the toxicity of chromium (VI) in hepatocytes. Toxicology in Vitro, 16 (5). pp. 509-516. ISSN 0887-2333

Jairaj, M. and Watson, D.G. and Grant, M.H. and Skellern, G.G. (2002) Toxicity of codeine, codeinone and oxycodone in hep g2 cells: identification of a codeinone-glutathione conjugate by lC/+ECI-MS/MS. In: 50th Meeting of the American Society for Mass Spectrometry, 2002-06-02 - 2002-06-06.

Stevenson, D. and Morgan, C. and Goldie, E.I. and Connel, G. and Grant, M.H. (2002) Viability and function of cryopreserved rat hepatocyte monolayers as a function of cryopreservation media composition. Toxicology, 178. pp. 55-56. ISSN 0300-483X

Denning, D.J. and Henderson, C.J. and Grant, M.H. (2002) The cytotoxicity of chromium in osteoblasts: effects on macromolecular synthesis. Journal of Materials Science: Materials in Medicine, 13 (1). pp. 47-52. ISSN 0957-4530

Atsriku, C. and Watson, D.G. and Grant, M.H. and Skellern, G.G. (2002) The effects of inducing agents on the metabolism of pentamidine in isolated hepatocytes. In: Pfizer Drug Discovery 2002, 1900-01-01.

Atsriku, C. and Skellern, G.G. and Watson, D.G. and Grant, M.H. (2002) The effects of inducing agents on the metabolism of trypanocidal diamidines by isolated rat hepatocytes. In: RSC-DMG 2002: New Technologies in Drug Discovery, 2002-12-12 - 2002-12-13.

Lalaouni, A. and Kupper, C. and Grant, M.H. (2002) The interaction of hexavalent chromium with mouse macrophages. Toxicology, 192 (1). p. 86. ISSN 0300-483X

Ganguli, A. and Henderson, C. and Grant, M.H. and Meikle, S.T. and Lloyd, A.W. and Goldie, I. (2002) The interactions of bisphosphonates in solution and as coatings on hydroxyapatite with osteoblasts. Journal of Materials Science: Materials in Medicine, 13 (10). pp. 923-931. ISSN 0957-4530

Kataropoulou, M. and Henderson, C.J. and Grant, M.H. (2002) The metabolism of kaempferol in primary hepatocytes cultured on collagen films and gels of different composition. In: RSC-DMG 2002: New Technologies in Drug Discovery, 2002-12-12 - 2002-12-13.

Gunaratnam, M. and Grant, M.H.; (2002) The toxicity of orthopaedic biomaterials chromium and nickel in rat hepatocytes. In: Transactions of the 28th Annual Meeting of the Society for Biomaterials. Society for Biomaterials. ISBN 8032087028

2001

Atsriku, C. and Skellern, G.G. and Watson, D.G. and Grant, M.H. (2001) High-performance liquid chromatographic determination of diminazene aceturate in the presence of its related substances. In: British Pharmaceutical Conference, 2001-09-23 - 2001-09-26.

Kaulek, V. and Sass, P. and Alexandre, E. and Grant, M.H. and Richert, L. and Jaeck, D. and Tiberghien, P. and Wolf, P. and Azimzadeh, A. (2001) Comparative phenotype and immunogenicity of freshly isolated and immortalized rat hepatocytes. Cell Transplantation, 10 (8). pp. 739-747. ISSN 0963-6897

Gunaratnam, M. and Grant, M.H. (2001) Glutathione reductase reduces chromium VI to cytotoxic metabolites in isolated rat hepatocytes. Toxicology, 168 (1). pp. 119-121. ISSN 0300-483X

Jairaj, M. and Watson, D.G. and Grant, M.H. and Skellern, G.G. (2001) Identification of metabolites of pholcodine by lC/MS. In: Proceedings of the Spring Symposium of the Chromatographic Society, 1900-01-01.

Boibessot, I. and Grant, M.H. and Skellern, G.G. and Watson, D.G. (2001) Isometamidium metabolism and distribution in rat hepatocytes. In: 26th Meeting of the International Scientific Council for Trypanosomiasis Research and Control, 2001-10-01 - 2001-10-05.

Jairaj, M. and Watson, D.G. and Grant, M.H. and Skellern, G.G. (2001) Metabolic profiling of the antitissive pholcodine in rat hepatocytes : identification of a novel metabolite by lC/+ESI- mS. In: 49th American Society for Mass Spectrometry Conference on Mass Spectrometry and Allied Topics, 2001-05-27 - 2001-05-31.

Atsriku, C. and Skellern, G.G. and Watson, D.G. and Grant, M.H. (2001) RP-HPLC determination of dimanazene aceturate in pharmaceutical preparations. In: 26th Meeting of the International Scientific Council for Trypanosomiasis Research and Control, 2001-10-01 - 2001-10-05.

Jairaj, M. and Skellern, G.G. and Watson, D.G. and Grant, M.H.; (2001) Study of the in vitro metabolism of the antitussive pholcodine: metabolic profiling and pharmacokinetics in isolated rat hepatocytes. In: British Pharmaceutical Conference: science proceedings, Glasgow, September 23rd - 26th, 2001. Pharmaceutical Press, GBR. ISBN 9780853695127

Grant, M.H. and Rogers, E.H. and Anderson, K.P. and Haydon, G.H. and Hayes, P.C. (2001) The effect of serum from liver cancer patients on the growth and function of primary and immortalised hepatocytes. International Journal of Artificial Organs, 24 (11). pp. 807-813. ISSN 0391-3988

McKegney, M. and Taggart, I. and Grant, M.H. (2001) The influence of crosslinking agents and diamines on the pore size, morphology and biological stability of collagen sponges, and their effect on cell penetration through the sponge matrix. Journal of Materials Science: Materials in Medicine, 12 (9). pp. 833-844. ISSN 0957-4530

Kataropoulou, M. and Henderson, C.J. and Grant, M.H.; (2001) The influence of glycosaminoglycans and crosslinking agents on the phenotype of hepatocytes cultured on collagen gels. In: Transactions of the 25th Annual Meeting of the Society for Biomaterials. Society for Biomaterials. ISBN 8024572001

Ganguli, A. and Lloyd, A.W. and Meikle, S.T. and Grant, M.H.; (2001) The interaction of bisphosphonate-coated hydroxyapatite and osteoblasts. In: Transactions of the 25th Annual Meeting of the Society for Biomaterials. Society for Biomaterials. ISBN 8024572001

Gunaratnam, M. and Grant, M.H. (2001) The interaction of the orthopaedic metals, chromium VI and nickel, with hepatocytes. Journal of Materials Science: Materials in Medicine, 12 (10-12). pp. 945-948. ISSN 0957-4530

Jairaj, M. and Watson, D.G. and Skellern, G.G. and Grant, M.H. (2001) The metabolism of the antitussive pholcodine in isolated rat hepatocytes: identification of a novel metabolite and toxicological implications. Toxicology, 168 (1). pp. 135-136. ISSN 0300-483X

Gunaratnam, M. and Grant, M.H. (2001) The role of glutathione reductase in the cytotoxicity of chromium (VI) in isolated rat hepatocytes. Chemico-Biological Interactions, 134 (2). pp. 191-202. ISSN 0009-2797

Stevenson, D. and Wokosin, D. and Girkin, J. and Grant, M.H. (2001) The use of monochlorobimane and confocal laser scanning microscopy to measure the intracellular distribution of reduced glutathione in rat hepatocytes. Toxicology, 168 (3). pp. 114-115. ISSN 0300-483X