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Open Access research that helps to deliver "better medicines"...

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An investigation into the compatibility of 5 potential binders for the production of artificial bone scaffolds

Dunham, April and Yan, Xiu and Grant, Mary (2011) An investigation into the compatibility of 5 potential binders for the production of artificial bone scaffolds. In: British Toxicology Society Meeting, 2011-09-05 - 2011-09-06.

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Abstract

Current practice of facial reconstruction is often below patients’ expectations. This could be improved by the use of 3D printed personalised bone scaffolds. In this study the biocompatibility of 5 potential binders for this process was investigated in vitro. None of the binders showed an overt toxic effect. However, all potential binders except for sodium trisilicate solution showed a cytostatic effect at concentrations of 100µM suggesting their use could result in an inhibitory affect on wound healing in vivo.