Combined treatment of biomatrices with nisin and pulsed electric fields as a potential decontamination method?

Griffiths, S. and Maclean, M. and MacGregor, S.J. and Anderson, J.G. and Grant, M.H. (2009) Combined treatment of biomatrices with nisin and pulsed electric fields as a potential decontamination method? European Cells and Materials, 18 (Suppl.). p. 18. ISSN 1473-2262

[thumbnail of strathprints018715]
Preview
Text (strathprints018715)
strathprints018715.pdf
Accepted Author Manuscript

Download (65kB)| Preview

    Abstract

    Pulsed electric field (PEF) treatment has been shown to achieve bacterial inactivation in collagen gels whilst retaining the ability of the collagen to function as a biomaterial [1, 2]. Nisin, an antimicrobial peptide, has been used widely as a food preservative and has shown bactericidal action against a number of Gram-positive bacteria [3]. The potential of nisin to increase the efficacy of PEF disinfection of collagen gels to be used for tissue engineering applications was investigated.

    ORCID iDs

    Griffiths, S., Maclean, M. ORCID logoORCID: https://orcid.org/0000-0001-5750-0397, MacGregor, S.J. ORCID logoORCID: https://orcid.org/0000-0002-0808-585X, Anderson, J.G. ORCID logoORCID: https://orcid.org/0000-0003-4151-1619 and Grant, M.H. ORCID logoORCID: https://orcid.org/0000-0002-7712-404X;