Galactosylated poly(ethylene glycol) as a scaffold for primary hepatocytes.
Hamilton, C and Henderson, C J and Ulijn, R V and Grant, M H (2012) Galactosylated poly(ethylene glycol) as a scaffold for primary hepatocytes. European Cells and Materials, 23 (Suppl ). p. 30. ISSN 1473-2262
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Maintaining stable cultures of viable and metabolically active primary hepatocytes is a long standing problem 1. Synthetic biomaterials with tuneable chemical properties may provide a suitable platform for the culture of primary cells. Hepatocytes are capable of binding terminal galactose residues via the hepatocyte asialoglycoprotein receptor (ASGPr); targeting of this receptor may facilitate binding of cells, influence morphology and ultimately improve cellular function 2
Creators(s): |
Hamilton, C ![]() ![]() ![]() | Item type: | Article |
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ID code: | 51206 |
Keywords: | hepatocyte scaffold, galactosylated poly(ethylene glycol), stable cultures, Bioengineering, Biochemistry, Biomaterials |
Subjects: | Technology > Engineering (General). Civil engineering (General) > Bioengineering |
Department: | Faculty of Engineering > Biomedical Engineering Technology and Innovation Centre > Bionanotechnology Faculty of Science |
Depositing user: | Pure Administrator |
Date deposited: | 22 Jan 2015 14:32 |
Last modified: | 17 Dec 2020 02:07 |
Related URLs: | |
URI: | https://strathprints.strath.ac.uk/id/eprint/51206 |
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