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2016

Subramaniam, Sudhakar Raja and Ellis, Elizabeth M. (2016) Umbelliferone and esculetin protect against N-nitrosodiethylamine-induced hepatotoxicity in rats. Cell Biology International, 40 (7). pp. 761-769. ISSN 1095-8355

2015

Lawal, Akeem O. and Marnewick, Jeanine L. and Ellis, Elizabeth M. (2015) Heme oxygenase-1 attenuates cadmium-induced mitochondrial-caspase 3- dependent apoptosis in human hepatoma cell line. BMC Pharmacology and Toxicology, 16. 41. ISSN 2050-6511

2014

Harwood, Thomas and Turton, David A. and Ellis, Elizabeth M. and Lapthorn, Adrian J. and Wynne, Klaas; (2014) Terahertz optical Kerr effect spectroscopy of biological molecules. In: International Conference on Infrared, Millimeter, and Terahertz Waves, IRMMW-THz. IEEE, USA. ISBN 9781479938773

Li, Dan and Ellis, Elizabeth M. (2014) Aldo–keto reductase 7A5 (AKR7A5) attenuates oxidative stress and reactive aldehyde toxicity in V79-4 cells. Toxicology in Vitro, 28 (4). pp. 707-714. ISSN 0887-2333

Turton, David A. and Senn, Hans Martin and Harwood, Thomas and Lapthorn, Adrian J. and Ellis, Elizabeth M. and Wynne, Klaas (2014) Terahertz underdamped vibrational motion governs protein-ligand binding in solution. Nature Communications, 5. 3999. ISSN 2041-1723

Li, Dan and Ellis, Elizabeth M (2014) 4-Hydroxynonenal induces an increase in expression of receptor for activating C Kinase 1 (RACK1) in Chinese hamster V79-4 lung cells. Chemico-Biological Interactions, 213. pp. 13-20. ISSN 0009-2797

Lawal, Akeem O. and Ellis, Elizabeth M. (2014) 2D-gel electrophoresis analysis of proteomic changes in three human cell lines; HEK 293, Hepg2 and 1321N1 cells in response to cadmium. Current Proteomics, 11 (1). pp. 27-36. ISSN 1875-6247

2013

Turton, David and Harwood, Thomas and Lapthorn, Adrian and Ellis, Elizabeth and Wynne, Klaas (2013) Ultrabroadband terahertz spectroscopies of biomolecules and water. Proceedings of SPIE: The International Society for Optical Engineering, 8623. 862303. ISSN 1996-756X

Subramaniam, Sudhakar R and Ellis, Elizabeth M (2013) Neuroprotective effects of umbelliferone and esculetin in a mouse model of Parkinson's disease. Journal of Neuroscience Research, 91 (3). 453–461.

Lyon, Robert C and Li, Dan and McGarvie, Gail and Ellis, Elizabeth M (2013) Aldo–keto reductases mediate constitutive and inducible protection against aldehyde toxicity in human neuroblastoma SH-SY5Y cells. Neurochemistry International, 62 (1). 113–121.

2012

Lapthorn, Adrian J and Zhu, Xiaofeng and Ellis, Elizabeth M (2012) The diversity of microbial aldo/keto reductases from Escherichia coli K12. Chemico-Biological Interactions.

Li, Dan and Ellis, Elizabeth (2012) Inducible protection of human astrocytoma 1321N1 cells against hydrogen peroxide and aldehyde toxicity by 7-hydroxycoumarin is associated with the upregulation of aldo-keto reductases. NeuroToxicology, 33 (5). pp. 1368-1374. ISSN 0161-813X

Lawal, Akeem O and Ellis, Elizabeth M (2012) Phospholipase C mediates cadmium-dependent apoptosis in HEK 293 cells. Basic and Clinical Pharmacology and Toxicology, 110 (6). pp. 510-517.

Ellis, Elizabeth (2012) Human aldo-keto reductase AKR7A2 protects against the cytotoxicity and mutagenicity of reactive aldehydes and lowers intracellular reactive oxygen species in hamster V79-4 cells. Chemico-Biological Interactions, 195 (1). pp. 25-34. ISSN 0009-2797

2011

Alzeer, S. and Ellis, E. M. (2011) The role of AKR1A1 in GHB biosynthesis and breakdown in HEPG2 cells. Toxicology, 290 (2-3). pp. 120-121. ISSN 0300-483X

Lawal, Akeem O and Ellis, Elizabeth M (2011) Nrf2-mediated adaptive response to cadmium-induced toxicity involves protein kinase C delta in human 1321N1 astrocytoma cells. Environmental toxicology and pharmacology, 32 (1). pp. 54-62.

Subramaniam, Sudhakar R and Ellis, Elizabeth M (2011) Esculetin-induced protection of human hepatoma HepG2 cells against hydrogen peroxide is associated with the Nrf2-dependent induction of the NAD(P)H : Quinone oxidoreductase 1 gene. Toxicology and Applied Pharmacology, 250 (2). pp. 130-136.

Lawal, Akeem O and Ellis, Elizabeth M (2011) The chemopreventive effects of aged garlic extract against cadmium-induced toxicity. Environmental toxicology and pharmacology, 32 (2). pp. 266-274.

Girkin, John M and Mohammed, Mazher-iqbal and Ellis, Elizabeth M (2011) A miniaturised integrated biophotonic point-of-care genotyping system. Faraday Discussions, 149. pp. 115-123. ISSN 1359-6640

Alzeer, Samar and Ellis, Elizabeth M (2011) The role of aldehyde reductase AKR1A1 in the metabolism of gamma-hydroxybutyrate in 1321N1 human astrocytoma cells. Chemico-Biological Interactions, 191. pp. 303-307.

2010

Lawal, Akeem Olalekan and Ellis, Elizabeth (2010) Differential sensitivity and responsiveness of three human cell lines HepG2, 1321N1 and HEK 293 to cadmium. Journal of Toxicological Sciences, 35 (4). pp. 465-78.

Raghunathan, Vijay Krishna and Grant, M.H. and Ellis, E. (2010) Changes in protein expression associated with chronic in vitro exposure of hexavalent chromium to osteoblasts and monocytes: a proteomic approach. Journal of Biomedical Materials Research Part A, 92A (2). pp. 615-625. ISSN 1549-3296

2009

Lawal, A.O. and Ellis, E.M. (2009) Intracellular ca2+ alteration via phospholipase c-inositol triphosphate and mitochondrial-caspase dependent pathways mediate cadmium-induced cell death. Toxicology, 262 (1). pp. 4-5. ISSN 0300-483X

Raghunathan, Vijay Krishna and Ellis, E. and Grant, M. Helen (2009) Response to chronic exposure to hexavalent chromium in human monocytes. Toxicology in Vitro, 23 (4). pp. 647-652. ISSN 0887-2333

Mohammed, Mazher-Iqbal and Sills, Graeme J. and Brodie, Martin J. and Ellis, E. and Girkin, J.M. (2009) A complete miniaturised genotyping system for the detection of single nucleotide polymorphisms in human DNA samples. Sensors and Actuators B: Chemical, 139 (1). pp. 83-90. ISSN 0925-4005

Raghunathan, V.K. and Tettey, J.N.A. and Ellis, E.M. and Grant, M.H. (2009) Comparative chronic in vitro toxicity of hexavalent chromium to osteoblasts and monocytes. Journal of Biomedical Materials Research Part A, 88A (2). pp. 543-550. ISSN 1549-3296

Pournamdari, M. and Saadi, Ahmed and Ellis, E. and Andrew, Ruth and Walker, Brian and Watson, D.G. (2009) Development of a derivatisation method for the analysis of aldehyde modified amino acid residues in proteins by Fourier transform mass spectrometry. Analytica Chimica Acta, 633 (2). pp. 216-222. ISSN 0003-2670

Lyon, Robert C. and Johnston, Stuart M. and Panopoulos, Andraes and Alzeer, Samar and McGarvie, Gail and Ellis, Elizabeth M. (2009) Enzymes involved in the metabolism of gamma-hydroxybutyrate in SH-SY5Y cells: Identification of an iron-dependent alcohol dehydrogenase ADHFe1. Chemico-Biological Interactions, 178 (1-3). pp. 283-287. ISSN 0009-2797

Ellis, E. (2009) Protection against aflatoxin B1 in rat - a new look at the link between toxicity, carcinogenicity, and metabolism. Toxicological Sciences, 109 (1). pp. 1-3. ISSN 1096-6080

2008

Lawal, A.O. and Ellis, E.M. (2008) Changes in antioxidant status in HepG2, 1321N1 and HEK 293 cells in response to cadmium induced-oxidative stress. Toxicology, 253 (1-3). pp. 1-2. ISSN 0300-483X

2007

Anthony, Nahoum Guillaume Hsuan and Breen, D. and Clarke, Joanna and Donoghue, Gavin and Drummond, Allan J. and Ellis, Elizabeth and Gemmell, Curtis G. and Helesbeux, Jean-Jacques and Hunter, Iain. S. and Khalaf, Abedawn and MacKay, Simon and Parkinson, J.A. and Suckling, C.J. and Waigh, R.D. (2007) Antimicrobial lexitropsins containing amide, amidine, and alkene linking groups. Journal of Medicinal Chemistry, 50 (24). pp. 6116-6125. ISSN 0022-2623

Lyon, R.C. and Johnston, S.M. and Watson, D.G. and McGarvie, G. and Ellis, E.M. (2007) Synthesis and catabolism of gamma-hydroxybutyrate in SH-SY5Y human neuroblastoma cells. Journal of Biological Chemistry, 282 (36). pp. 25986-25992. ISSN 1083-351X

Raghunathan, Vijay Krishna and Ellis, Elizabeth M. and Tettey, Justice N.A. and Grant, M. Helen (2007) Involvement of reduced glutathione and glutathione reductase in the chronic toxicity of hexavalent chromium to monocytes in vitro. Toxicology, 231 (2-3). pp. 105-106. ISSN 0300-483X

Raghunathan, Vijay Krishna and Tettey, J.N.A. and Ellis, E. and Grant, M.H. (2007) Changes in antioxidant enzymes during chronic in vitro exposure to chromium. In: British Toxicology Society Meeting, 2007-09-01.

2006

Raghunathan, V.K. and Ellis, E.M. and Grant, M.H. (2006) Chronic toxicity of hexavalent chromium to U937 human monocyte cell line. In: BioScience 2006: Bioscience in the 21st Century, 2006-07-23 - 2006-07-27.

Zhu, X. and Lapthorn, A.J. and Ellis, E. (2006) Crystal structure of mouse succinic semialdehyde reductase AKR7A5: structural basis for substrate specificity. BMC Biochemistry, 45 (6). pp. 1562-1570. ISSN 1471-2091

Short, D.M. and Lyon, R.C. and Watson, D.G. and Barski, O.A. and McGarvie, G. and Ellis, E. (2006) Metabolism of trans, trans-muconaldehyde, a cytotoxic metabolite of benzene, in mouse liver by alcohol dehydrogenase Adh1 and aldehyde reductase AKR1A4. Toxicology and Applied Pharmacology, 210 (1-2). pp. 163-170. ISSN 0041-008X

Raghunathan, Vijay Krishna and Duffin, B. and Oladokun, G. and Ellis, E. and Tettey, J.N.A. and Meek, R.M.D. and Murray, H.M. and Grant, M.H. (2006) Osteoblast and monocyte function after chronic exposure to metal ions. In: Proceedings of the Meeting on Biological Implications of Metal-on-Metal Articulations, 2006-11-01.

2003

Ellis, E. and Slattery, C.M. and Hayes, J.D. (2003) Characterization of the rat aflatoxin B1 aldehyde reductase gene, AKR7A1. Structure and chromosomal localization of AKR7A1 as well as identification of antioxidant response elements in the gene promoter. Carcinogenesis, 24 (4). pp. 727-737. ISSN 0143-3334

Kozma, E. and Brown, E. and Ellis, E. and Lapthorn, A. (2003) The high resolution crystal structure of rat liver AKR7A1 understanding the substrate specificities of the AKR7 family. Chemico-Biological Interactions, 143. pp. 289-297. ISSN 0009-2797

2002

Hayes, J.D. and Kelly, V.P. and Slattery, C.M. and Ellis, E.M. (2002) Aflatoxin aldehyde reductases. Chemical Research in Toxicology, 15 (12). p. 1656. ISSN 0893-228X

Ellis, E. and Gardner, Rachel A. and Li, Dan and Grant, Anne W. (2002) Role of akr7a aldo-keto reductases in the detoxication of aldehydes and ketones. Chemical Research in Toxicology, 15 (12). p. 1666. ISSN 0893-228X

Grant, Anne W. and Staffas, Louise and Mankowitz, Louise and Kelly, Vincent P. and Manson, Margaret M. and DePierre, Joseph W. and Hayes, John D. and Ellis, E.M. (2002) Erratum to 'Expression of rat aldehyde reductase AKR7A1: influence of age and sex and tissue-specific inducibility' [Biochemical Pharmacology V.62 (2001) 1511-1519]. Biochemical Pharmacology, 64 (2). p. 353. ISSN 0006-2952

Hinshelwood, A. and McGarvie, G. and Ellis, E. (2002) Characterisation of a novel mouse liver aldo-keto reductase AKR7A5. FEBS Letters, 523 (1-3). pp. 213-218. ISSN 0014-5793

Kozma, E. and Brown, E. and Ellis, E. and Lapthorn, A. (2002) The crystal structure of rat liver AKR7A1: a dimeric member of the Aldo-Keto reductase superfamily. Journal of Biological Chemistry, 277 (18). pp. 16285-16293. ISSN 1083-351X

2001

Grant, A. and Staffas, L. and Mancowiz, L. and Kelly, V.P. and Manson, M.M. and DePierre, J.W. and Hayes, J.D. and Ellis, E.M. (2001) Expression of rat aldehyde reductase AKR7A1: influence of age and sex and tissue-specific inducibility. Biochemical Pharmacology, 62 (11). pp. 1511-1519. ISSN 0006-2952