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2013

Gibriel, Abdullah and Tate, Rothwelle and Yu, Yongbin and Rawson-Lax, E. and Hammer, HM and Tettey, Justice Nii Addy and Pyne, Nigel and Converse, Carolyn (2013) The p.Arg86Gln change in GARP2 (glutamic acid-rich protein-2) is a common West African-related polymorphism. Gene, 515 (1). pp. 155-158. ISSN 0378-1119

2010

Afolaranmi, G. and Tettey, J.N.A. and Murray, H.M. and Meek, R.M.D. and Grant, M.H. (2010) The effect of anticoagulants on the distribution of chromium VI in blood fractions relevance to patients with metal orthopedic implants. Journal of Arthroplasty, 25 (1). pp. 118-120. ISSN 1532-8406

2009

Afolaranmi, G.A. and Tettey, J.N.A. and Murray, H.M. and Meek, R.M.D. and Farmer, J. and Eades, L.J. and Grant, M.H. (2009) Blood chromium and cobalt levels after Durom hip resurfacing. In: British Orthopaedic Research Society Annual Meeting, 2009-06-22 - 2009-06-23. (Unpublished)

Sinclair, J.A. and Henderson, C.J. and Martin, I.K. and Grant, M.H. and Tettey, J.N.A. (2009) The extent of phase I and phase II reactions is affected by the choice of enzyme used to prepare rat hepatocytes. Chemico-Biological Interactions, 179 (2-3). pp. 256-262. ISSN 0009-2797

Coxon, Geoffrey D. and Furman, Brian L. and Harvey, Alan L. and McTavish, John and Mooney, Mark H. and Arastoo, Mahmoud and Kennedy, A.R. and Tettey, J.N.A. and Waigh, R.D. (2009) Benzylguanidines and other galegine analogues inducing weight loss in mice. Journal of Medicinal Chemistry, 52 (11). pp. 3457-3463. ISSN 0022-2623

Thi, M.D. and Grant, M.H. and Mullen, Alexander B. and Tettey, J.N.A. and Mackay, S.P. and Clark, Rachael L. (2009) Metabolism of two new benzodiazepine-type anti-leishmanial agents in rat hepatocytes and hepatic microsomes and their interaction with glutathione in macrophages. Journal of Pharmacy and Pharmacology, 61 (3). pp. 399-406. ISSN 0022-3573

Raghunathan, V.K. and Tettey, J.N.A. and Ellis, E.M. and Grant, M.H. (2009) Comparative chronic in vitro toxicity of hexavalent chromium to osteoblasts and monocytes. Journal of Biomedical Materials Research Part A, 88A (2). pp. 543-550. ISSN 1549-3296

2008

Zheng, L. and Watson, D.G. and Tettey, J.N.A. and Clements, C.A. (2008) The determination of iron as its EDTA complex in Helix aspera by hydrophilic interaction liquid chromatography coupled to Fourier transform electrospray ionisation mass spectrometry. Talanta, 76 (5). pp. 1165-1169. ISSN 0039-9140

Kadi, A.A. and El-Kashef, H.A. and Abdel-Aziz, A.A.M. and Hassan, G. and Tettey, J.N.A. and Grant, M.H. and Lehmann, J. and El-Subbagh, H.I. (2008) Synthesis, ultra-short acting hypnotic activity, and metabolic profile of ethyl 8-oxo-5,6,7,8-tetrahydro-thiazolo[3,2-a] [1,3]diazepin-3-carboxylate (HIE-124). ChemInform, 39 (22). ISSN 1522-2667

Kadi, A.A. and Ei-Kashef, H.A. and Abdel-Aziz, A.A.M. and Hassan, G.S. and Tettey, J.N.A. and Grant, M.H. and Lehmann, J. and EI-Subbagh, H.I. (2008) Synthesis, Ultra-Short Acting Hypnotic Activity, and Metabolic Profile of Ethyl 8-Oxo-5,6,7,8-tetrahydro-thiazolo[3,2-a] [1,3]diazepin-3-carboxylate (HIE-124). Archiv der Pharmazie, 341 (2). pp. 81-89. ISSN 0365-6233

Schad, G.J. and Allanson, A. and Mackay, S.P. and Cannavan, A. and Tettey, J.N.A. (2008) Development and validation of an improved hplc method for the control of potentially counterfeit isometamidium products. Journal of Pharmaceutical and Biomedical Analysis, 46 (1). pp. 45-51. ISSN 1873-264X

EI-Subbagh, H.I. and El-Kashef, H.A. and Kadi, A.A. and Abdel-Aziz, A.A.M. and Hassan, G.S. and Tettey, J.N.A. and Lehmann, J. (2008) New ultra-short acting hypnotic: Synthesis, biological evaluation, and metabolic profile of ethyl 8-oxo-5,6,7,8-tetrahydro-thiazolo[3,2-a][1,3]diazepin-3-carboxylate (HIE-124). Bioorganic and Medicinal Chemistry Letters, 18 (1). pp. 72-77. ISSN 0960-894X

Lau, S.S.M. and Stainforth, N.M. and Watson, D.G. and Skellern, G.G. and Wren, S.A.C. and Tettey, J.N.A. (2008) Ce hydrogen deuterium exchange-ms in peptide analysis. Electrophoresis, 29 (2). pp. 393-400. ISSN 0173-0835

Sinclair, J.A. and Henderson, C.J. and Martin, I.J. and Grant, M.H. and Tettey, J.N.A. (2008) MRP2 transport function in rat hepatocytes and the effect of the liver digestion enzyme. Drug Metabolism Reviews, 40 (Supple). p. 100. ISSN 0360-2532

Afolaranmi, G.A. and Tettey, J.N.A. and Meek, R.M.D. and Grant, M.H. (2008) Release of chromium from orthpaedic arthroplasties. Open Orthopaedics Journal, 2 (9). pp. 10-18. ISSN 1874-3250

Zhang, Tong and Khadra, Ibrahim and Euerby, Melvin R. and Skellern, G.G. and Watson, David G. and Tettey, J.N.A. (2008) Simultaneous analysis of basic, acidic and neutral compounds on an endcapped octadecylsilane silica-based monolith by pressure-assisted capillary electrochromatography. Electrophoresis, 29 (4). pp. 944-951. ISSN 0173-0835

Sinclair, J.A. and Henderson, C.J. and Martin, I.K. and Grant, M.H. and Tettey, J.N.A. (2008) Trypsin inhibitor may increase the formation of GSH conjugates of potentially toxic reactive intermediates in isolated rat hepatocytes. Journal of Pharmacy and Pharmacology, 60 (59). A24-A25. ISSN 0022-3573

Raghunathan, V.K. and Tettey, J.N.A. and Grant, M.H. (2008) Uptake of Cr (VI) and Cr (III)-GSH complex across rat liver cell nuclei. Toxicology, 253 (1-3). pp. 20-21. ISSN 0300-483X

Afolaranmi, G.A. and Tettey, J.N.A. and Gaylor, J.D.S. and Murray, H.M. and Meek, R.M.D. and Grant, M.H. (2008) Uptake of chromium into red blood cells does not affect the ability of haemoglobin to bind oxygen. Toxicology, 253 (1-3). pp. 15-16. ISSN 0300-483X

2007

Duong Thi, M.D. and Clarke, R. and Mackay, S.P. and Mullen, A.B. and Tettey, J.N.A. and Grant, M.H. (2007) Metabolism and toxicity of two new benzodiazepine-type antileishmanial agents in hepatocytes and macrophages. Toxicology, 231 (2-3). pp. 104-105. ISSN 0300-483X

Raghunathan, Vijay Krishna and Ellis, Elizabeth M. and Tettey, Justice N.A. and Grant, M. Helen (2007) Involvement of reduced glutathione and glutathione reductase in the chronic toxicity of hexavalent chromium to monocytes in vitro. Toxicology, 231 (2-3). pp. 105-106. ISSN 0300-483X

Clark, Rachael L. and Carter, Katharine C. and Mullen, Alexander B. and Coxon, Geoffrey D. and Owusu-Dapaah, George and McFarlane, Emma and Dao Duong Thi, M. and Grant, M.H. and Tettey, J.N.A. and Mackay, Simon P. (2007) Identification of the benzodiazepines as a new class of antileishmanial agent. Bioorganic and Medicinal Chemistry Letters, 17 (3). pp. 624-627. ISSN 0960-894X

Ibrahim, H. and El-Sabbagh, N.M. and Changtam, C. and Gould, M. and Grant, M.H. and Tettey, J.N.A. and Vance, S. and Cooper, A. and Suksamrarn, A. and De Koning, H.P. (2007) Analogues of curcumin as a new class of antiprotozoals. In: Medicinal Chemistry in Parasitology: new avenues in, 2007-02-01.

Raghunathan, Vijay Krishna and Tettey, J.N.A. and Ellis, E. and Grant, M.H. (2007) Changes in antioxidant enzymes during chronic in vitro exposure to chromium. In: British Toxicology Society Meeting, 2007-09-01.

Sinclair, J.A. and Henderson, C.J. and Martin, I.J. and Grant, M.H. and Tettey, J.N.A. (2007) Collagenase - alone or in combination for the preparation of hepatocytes? The effect on phase 1 and phase 2 biotransformations. Journal of Pharmacy and Pharmacology, 59 (S1). A16. ISSN 0022-3573

Allanson, A.L. and Cotton, M.M. and Tettey, J.N.A. and Boyter, A.C. (2007) Determination of rifampicin in human plasma and blood spots by high performance liquid chromatography with uV detection: a potential method for therapeutic drug monitoring. Journal of Pharmaceutical and Biomedical Analysis, 44 (4). pp. 963-969. ISSN 1873-264X

Zhang, T. and Watson, D.G. and Tettey, J.N.A. and Stearns, A.T. and Binning, A.R. and Payne, C.J. (2007) Determination of vancomycin in serum by liquid chromatography-high resolution full scan mass spectrometry. Journal of Chromatography B, 857 (2). pp. 352-356. ISSN 1570-0232

Boibessot, I. and Tettey, J.N.A. and Skellern, G.G. and Grant, M.H. (2007) Toxicity of phenanthridine trypanocides in primary cultures of hepatocytes: Interaction with reduced glutathione. In: British Toxicology Society Meeting, 2007-09-01.

Sinclair, J.A. and Henderson, C.J. and Martin, I.K. and Grant, M.H. and Tettey, J.N.A. (2007) The digestion enzyme used in isolation procedures influences metabolic capacity of hepatocytes. In: Life Sciences 2007, 2007-07-09 - 2007-07-10, SECC.

Afolaranmi, G.A. and Tettey, J.N.A. and Murray, H. and Meek, R.M.D. and Grant, M.H. (2007) The effect of anticoagulants on the distribution of chromium (VI) in blood fractions. Journal of Pharmacy and Pharmacology, 59 (S1). A4. ISSN 0022-3573

Afolaranmi, G.A. and Tettey, J.N.A. and Gaylor, J.D.S. and Murray, H.M. and Meek, R.M.D. and Grant, M.H. (2007) The effect of chromium on the oxygen uptake capacity of blood. In: Life Sciences 2007, 2007-07-09 - 2007-07-10, SECC.

2006

Boibessot, I. and Tettey, J.N.A. and Skellern, G.G. and Watson, D.G. and Grant, M.H. (2006) The metabolism of isometamidium in hepatocytes from control and inducer treated rats. Journal of Veterinary Pharmacology and Therapeutics, 29 (6). pp. 547-553. ISSN 0140-7783

Meechan, A.J. and Henderson, C. and Bates, Catharine D. and Grant, M.H. and Tettey, J.N.A. (2006) Metabolism of troglitazone in hepatocytes isolated from experimentally induced diabetic rats. Journal of Pharmacy and Pharmacology, 58 (10). pp. 1359-1365. ISSN 0022-3573

Raghunathan, Vijay Krishna and Duffin, B. and Oladokun, G. and Ellis, E. and Tettey, J.N.A. and Meek, R.M.D. and Murray, H.M. and Grant, M.H. (2006) Osteoblast and monocyte function after chronic exposure to metal ions. In: Proceedings of the Meeting on Biological Implications of Metal-on-Metal Articulations, 2006-11-01.

Sinclair, J.A. and Henderson, C.J. and Grant, M.H. and Martin, I.J. and Tettey, J.N.A. (2006) The influence of digestion enzymes on the metabolic stability of rat hepatocytes. In: Drug Metabolism Discussion Group Meeting, 2006-04-27 - 2006-04-28.

2005

Adu, J.K. and Lau, S. and Watson, D.G. and Euerby, M.R. and Skellern, G.G. and Tettey, J.N.A. (2005) Capillary electrochromatography of therapeutic peptides on mixed-mode butylmethacrylate monoliths. Electrophoresis, 26 (18). pp. 3445-3451. ISSN 0173-0835

Kenny, J.R. and Maggs, J.L. and Tettey, J.N.A. and Harrell, A.W. and Parker, S.G. and Clarke, S.E. and Park, B.K. (2005) Formation and protein binding of the acyl glucuronide of a leukotriene b4 antagonist (sb-209247) relation to species differences in hepatotoxicity. Drug Metabolism and Disposition, 33 (2). pp. 271-281. ISSN 1521-009X

2004

Meechan, A.J. and Henderson, C.J. and Coxon, Geoff and Tettey, J.N.A. and Grant, M.H. (2004) Evaluation of the toxicity of a substituted 2,4-thiazolidinedione moiety to isolated rat hepatocytes : relevance to glitazone toxicity. pA2 Online: E Journal of the British Pharmacological Society, 2 (4).

Bohlooli, S. and Mahmoudian, M. and Skellern, G.G. and Grant, M.H. and Tettey, J.N.A. (2004) Metabolism of the novel dihydropyridine calcium channel blockers mebudipine and dibudipine by isolated rat hepatocytes. Journal of Pharmacy and Pharmacology, 56. pp. 1469-1475. ISSN 0022-3573

Ball, A.J. and Tettey, J.N.A. and Grant, M.H. (2004) The toxicity of troglitazone, roziglitazone and vitamin e in human hep g2 hepatoma cells. Toxicology, 194 (3). pp. 250-251. ISSN 0300-483X

2002

Atsriku, C. and Watson, D.G. and Tettey, J.N.A. and Grant, M.H. and Skellern, G.G. (2002) Determination of diminazene aceturate in pharmaceutical formulations by HPLC and identification of related substances by lC/MS. Journal of Pharmaceutical and Biomedical Analysis, 30 (4). pp. 979-986. ISSN 1873-264X

2001

Owen, A. and Pirmohamed, M. and Tettey, J.N.A. and Morgan, P. and Chadwick, D. and Park, B.K. (2001) Carbamazepine is not a substrate for p-glycoprotein. British Journal of Clinical Pharmacology, 51 (4). pp. 345-349. ISSN 0306-5251

Tettey, J.N.A. and Maggs, J.L. and Rapeport, W.G. and Pirmohamed, M. and Park, B.K. (2001) Enzyme-induction dependent bioactivation of troglitazone and troglitazone quinine in vivo. Chemical Research in Toxicology, 14 (8). pp. 965-974. ISSN 0893-228X