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2023

Topuz Ata, Derya and Hussain, Muattaz and Jones, Michael and Best, Jonathan and Wiese, Martin and Carter, Katharine Christine (2023) Immunisation with transgenic L. tarentolae expressing gamma glutamyl cysteine synthetase from pathogenic Leishmania species protected against L. major and L. donovani infection in a murine model. Microorganisms, 11 (5). 1322. ISSN 2076-2607

2022

Perieteanu, Marina C. and McGee, Leah M.C. and Shaw, Craig D. and MacMillan, Donna S. and Khalaf, Abedawn I. and Gillingwater, Kirsten and Beveridge, Rebecca and Carter, Katharine C. and Suckling, Colin J. and Scott, Fraser J. (2022) Selective anti-Leishmanial Strathclyde minor groove binders using an N-oxide tail group modification. International Journal of Molecular Sciences, 23 (19). 11912. ISSN 1422-0067

Kieswetter, Nathan S. and Ozturk, Mumin and Hlaka, Lerato and Chia, Julius Ebua and Nichol, Ryan J. O. and Cross, Jasmine M. and McGee, Leah and Tyson-Hirst, Izaak and Beveridge, Rebecca and Brombacher, Frank and Carter, Katharine C. and Suckling, Colin J. and Scott, Fraser J. and Guler, Reto (2022) Intranasally administered S-MGB-364 displays antitubercular activity and modulates the host immune response to mycobacterium tuberculosis infection. Journal of Antimicrobial Chemotherapy, 77 (4). pp. 1061-1071. ISSN 0305-7453

2021

Brooke, Daniel P. and McGee, Leah M. C. and Giordani, Federica and Cross, Jasmine M. and Khalaf, Abedawn I. and Irving, Craig and Gillingwater, Kirsten and Shaw, Craig D. and Carter, Katharine C. and Barrett, Michael P. and Suckling, Colin J. and Scott, Fraser J. (2021) Correction : Truncated S-MGBs: towards a parasite-specific and low aggregation chemotype. RSC Medicinal Chemistry, 12 (12). p. 2071.

Brooke, Daniel P. and McGee, Leah M. C. and Giordani, Federica and Cross, Jasmine M. and Khalaf, Abedawn I. and Irving, Craig and Gillingwater, Kirsten and Shaw, Craig D. and Carter, Katharine C. and Barrett, Michael P. and Suckling, Colin J. and Scott, Fraser J. (2021) Truncated S-MGBs : towards a parasite-specific and low aggregation chemotype. RSC Medicinal Chemistry, 12 (8). pp. 1391-1401. ISSN 2040-2511

Miret, Jorge A. and Moreno, Javier and Nieto, avier and Carter, Katharine C. and Mullen, Alexander B. and Ambros, Luis and Rodríguez, Casilda and San Andrés, Manuel Ignacio and González, Fernado (2021) Antileishmanial efficacy and tolerability of combined treatment with non-ionic surfactant vesicle formulations of sodium stibogluconate and paromomycin in dogs. Experimental Parasitology, 220. 108033. ISSN 0014-4894

2020

Ahmed, Humera and Curtis, Charlotte R. and Tur-Gracia, Sara and Olatunji, Toluwanimi O. and Carter, Katharine C. and Williams, Roderick A. M. (2020) Drug combinations as effective anti-leishmanials against drug resistant Leishmania mexicana. RSC Medicinal Chemistry, 11 (8). pp. 905-912. ISSN 2040-2511

Ahmed, Humera and Carter, Katharine C. and Williams, Roderick A.M. (2020) Structure and antiparasitic activity relationship of alkylphosphocholine analogues against Leishmania donovani. Microorganisms, 8 (8). 1117. ISSN 2076-2607

Aruleba, Raphael Taiwo and Carter, Katharine C. and Brombacher, Frank and Hurdayal, Ramona (2020) Can we harness immune responses to improve drug treatment in leishmaniasis? Microorganisms, 8 (7). pp. 1-20. 1069. ISSN 2076-2607

Obeid, Mohammad A. and Teeravatcharoenchai, Teeranun and Connell, David and Niwasabutra, Kanidta and Hussain, Muattaz and Carter, Katharine and Ferro, Valerie A. (2020) Examination of the effect of niosome preparation methods in encapsulating model antigens on the vesicle characteristics and their ability to induce immune responses. Journal of Liposome Research, 31 (2). pp. 195-202. ISSN 0898-2104

2019

Shaw, C. D. and Imamura, H. and Downing, T. and Blackburn, G. and Westrop, G. D. and Cotton, J. A. and Berriman, M. and Sanders, M. and Rijal, S. and Coombs, G. H. and Dujardin, J. C. and Carter, K. C. (2019) Genomic and metabolomic polymorphism among experimentally selected paromomycin-resistant Leishmania donovani strains. Antimicrobial Agents and Chemotherapy, 64. e00904-19. ISSN 0066-4804

McFarlane, Emma and Mokgethi, Thabang and Kaye, Paul M. and Hurdayal, Ramona and Brombacher, Frank and Alexander, James and Carter, Katharine C. (2019) IL-4 mediated resistance of BALB/c mice to visceral leishmaniasis is independent of IL-4Rα signaling via T cells. Frontiers in Immunology, 10. 1957. ISSN 1664-3224

2017

Hlaka, Lerato and Rosslee, Michael-Jon and Ozturk, Mumin and Kumar, Santosh and Parihar, Suraj and Brombacher, Frank and Khalaf, Abedawn and Carter, Katharine and Scott, Fraser and Suckling, Colin and Guler, Reto (2017) Evaluation of minor groove binders (MGBs) as novel anti-mycobacterial agents, and the effect of using non-ionic surfactant vesicles as a delivery system to improve their efficacy. Journal of Antimicrobial Chemotherapy, 72 (12). 3334–3341. ISSN 0305-7453

Carter, Katharine C. and Mullen, Alexander B.; Rivas, Luis and Gil, Carmen, eds. (2017) New avenues for drug delivery in Leishmania : using treatment of visceral leishmaniasis with amphotericin B as an exemplar. In: Drug Discovery in Leishmaniasis. Royal Society of Chemistry, Croydon, 224 - 234. ISBN 9781788012584

2016

Scott, Fraser and Khalaf, Abedawn and Suckling, Colin and Carter, Katharine and Grant, Mary and Henderson, Catherine and Westrop, Gareth and Watson, David (2016) An evaluation of minor groove binders as anti-lung cancer therapeutics. Bioorganic and Medicinal Chemistry Letters, 26 (15). pp. 3478-3486. ISSN 0960-894X

Siheri, Weam and Zhang, Tong and Ebiloma, Godwin Unekwuojo and Biddau, Marco and Woods, Nicola and Hussain, Muattaz Yassein and Clements, Carol J. and Fearnley, James and Edrada Ebel, RuAngelie and Paget, Timothy and Müller, Sylke and Carter, Katharine C. and Ferro, Valerie A. and De Koning, Harry P. and Watson, David G. (2016) Chemical and antimicrobial profiling of propolis from different regions within Libya. PLOS One, 11 (5). e0155355. ISSN 1932-6203

Shaw, C. D. and Lonchamp, J. and Downing, T. and Imamura, H. and Freeman, T. M. and Cotton, J. A. and Sanders, M. and Blackburn, G. and Dujardin, J. C. and Rijal, S. and Khanal, B. and Illingworth, C. J. R. and Coombs, G. H. and Carter, K. C. (2016) In vitro selection of miltefosine resistance in promastigotes of Leishmania donovani from Nepal : genomic and metabolomic characterization. Molecular Microbiology, 99 (6). pp. 1134-1148. ISSN 0950-382X

Carter, K.C. and Puig-Sellart, M. (2016) Nanocarriers made from non-ionic surfactants or natural polymers for pulmonary drug delivery. Current Pharmaceutical Design, 22 (22). pp. 3324-3331. ISSN 1381-6128

2014

Siheri, Weam and Igoli, John O. and Gray, Alexander I. and Nasciemento, Ticiano G. and Zhang, Tong and Fearnley, James and Clements, Carol J. and Carter, Katharine C. and Carruthers, John and Edrada-Ebel, RuAngelie and Watson, David G. (2014) The isolation of antiprotozoal compounds from Libyan propolis. Phytotherapy Research, 28 (12). 1756–1760. ISSN 1099-1573

Shaw, CD and Carter, KC (2014) Lessons to be learnt from Leishmania studies. Nanomedicine, 9 (10). pp. 1531-1544. ISSN 1743-5889

2013

Alsaadi, Manal M. and Carter, K. Christine and Mullen, Alexander B. (2013) High performance liquid chromatography with evaporative light scattering detection for the characterisation of a vesicular delivery system during stability studies. Journal of Chromatography A, 1320. pp. 80-85. ISSN 0021-9673

2012

Carter, Katharine and Ross, K. and Tacchini-Cottier, F. and Lawrence, C. (2012) The role of mast cells in protection against Leishmania donovani infection. Immunology, 137 (1 spec). pp. 562-563. ISSN 0019-2805

Italia, Jagdishbhai Laxmanbhai and Kumar, M.N.V Ravi and Carter, Katharine (2012) Evaluating the potential of polyester nanoparticles for per oral delivery of amphotericin B in treating visceral leishmaniasis. Journal of Biomedical Nanotechnology, 8 (4). pp. 695-702. ISSN 1550-7033

Alsaadi, Manal and Italia, Jagdishbhai Laxmanbhai and Mullen, Alexander and Kumar, M.N.V Ravi and Candlish, A.A. and Williams, Roderick and Shaw, C.D. and Al-Gawhari, Fatima and Coombs, Graham and Wiese, Martin and Thomson, Alison and Puig-Sellart, M. and Wallace, J. and Sharp, A and Wheeler, Lee and Warn, Peter and Carter, Katharine (2012) The efficacy of aerosol treatment with non-ionic surfactant vesicles containing amphotericin B in rodent models of leishmaniasis and pulmonary aspergillosis infection. Journal of Controlled Release, 160 (3). pp. 685-691. ISSN 0168-3659

Hendrickx, Sarah and Inocêncio da Luz, Raquel Andrea and Bhandari, V. and Kuypers, K. and Shaw, Craig and Lonchamp, Julien and Salotra, P. and Carter, Katharine and Carter, Katharine and Sundar, S. and Rijal, S. and Dujardin, Jean-Claude and Cos, Paul and Maes, Louis (2012) Experimental induction of paromomycin resistance in antimony-resistant strains of L. donovani : outcome dependent on in vitro selection protocol. PLOS Neglected Tropical Diseases, 6 (5). e1664. ISSN 1935-2727

Carter, Katharine and Roberts, Craig and Doro, Basma Mohamed and Alsaadi, Manal and Mullen, Alexander and Campbell, Samantha and Alawa, Judith and Alawa, Clement and Nok, Andrew (2012) Comparative assessment of a DNA and protein Leishmania donovani gamma glutamyl cysteine synthetase vaccine to cross-protect against murine cutaneous leishmaniasis caused by L. major or L. mexicana infection. Vaccine, 30 (7). pp. 1357-1363. ISSN 1873-2518

2011

Italia, Jagdishbhai L and Sharp, Andrew and Carter, Katharine C and Warn, Peter and Kumar, M N V Ravi (2011) Peroral amphotericin B polymer nanoparticles lead to comparable or superior in vivo antifungal activity to that of intravenous Ambisome® or Fungizone™. PLoS One, 6 (10). e25744.

McFarlane, Emma and Carter, Katharine C and McKenzie, Andrew N and Kaye, Paul M and Brombacher, Frank and Alexander, James (2011) Endogenous IL-13 plays a crucial role in liver granuloma maturation during Leishmania donovani infection, independent of IL-4R alpha-responsive macrophages and neutrophils. Journal of Infectious Diseases, 204 (1). pp. 36-43.

2010

Henriquez, F. L. and Campbell, S. A. and Roberts, C. W. and Mullen, A. B. and Burchmore, R. and Carter, K. C. (2010) Vaccination with recombinant Leishmania donovani gamma-glutamylcysteine synthetase fusion protein protects against L. donovani infection. Journal of Parasitology, 96 (5). pp. 929-936.

2009

Mann, Jamie F S and Shakir, Eisin and Carter, Katharine C and Mullen, Alexander B and Alexander, James and Ferro, Valerie A (2009) Lipid vesicle size of an oral influenza vaccine delivery vehicle influences the Th1/Th2 bias in the immune response and protection against infection. Vaccine, 27 (27). pp. 3643-3649. ISSN 1873-2518

2008

McFarlane, E. and Perez, C. and Charmoy, M. and Allenbach, C. and Carter, K.C. and Alexander, J. and Tacchini-Cottier, F. (2008) Neutrophils contribute to development of a protective immune response during onset of infection with Leishmania donovani. Infection and Immunity, 76 (2). pp. 532-541. ISSN 0019-9567

Jones, L.A. and Anthony, J. and Henriquez, F.L. and Lyons, R. and Nickdel, M.B. and Carter, K.C. and Alexander, J. and Roberts, C.W. (2008) Toll-like receptor-4-mediated macrophage activation is differentially regulated by progesterone via the glucocorticoid and progesterone receptors. Immunology, 125 (1). pp. 59-69. ISSN 0019-2805

2007

McBride, James and Mullen, Alexander B. and Carter, K. Christine and Roberts, Craig W. (2007) Differential cytotoxicity of phospholipid analogues to pathogenic Acanthamoeba species and mammalian cells. Journal of Antimicrobial Chemotherapy, 60 (3). pp. 521-525. ISSN 0305-7453

Carter, K. C. and Henriquez, F. L. and Campbell, S. A. and Roberts, C. W. and Nok, A. and Mullen, A. B. and McFarlane, E. (2007) DNA vaccination against the parasite enzyme gamma-glutamylcysteine synthetase confers protection against Leishmania donovani infection. Vaccine, 25 (22). pp. 4502-4509. ISSN 1873-2518

Clark, Rachael L. and Carter, Katharine C. and Mullen, Alexander B. and Coxon, Geoffrey D. and Owusu-Dapaah, George and McFarlane, Emma and Dao Duong Thi, M. and Grant, M.H. and Tettey, J.N.A. and Mackay, Simon P. (2007) Identification of the benzodiazepines as a new class of antileishmanial agent. Bioorganic and Medicinal Chemistry Letters, 17 (3). pp. 624-627. ISSN 0960-894X

2006

Mullen, Alexander B. and Lawrence, Catherine E. and McFarlane, Emma and Wei, Xiao-Quing and Carter, Katharine C. (2006) Endogenous interleukin-18 is involved in immunity to Leishmania donovani but its absence does not adversely influence the therapeutic activity of sodium stibogluconate. Immunology, 119 (3). pp. 348-354. ISSN 0019-2805

Alexander, J. and Mann, J.F.S. and Scales, H.E. and Shakir, E. and Carter, K.C. and Mullen, A. and Ferro, V.A. (2006) Oral delivery of tetanus toxoid using vesicles containing bile salts (bilosomes) induces significant systemic and mucosal immunity. Methods, 38 (2). pp. 90-95. ISSN 1046-2023

Carter, K.C. and Hutchison, S. and Henriquez, F.L. and Legare, M. and Ouellette, M. and Roberts, C.W. and Mullen, A. (2006) Resistance of leishmania donovani to sodium stibogluconate is related to the expression of host and parasite gamma-glutamylcysteine synthetase. Antimicrobial Agents and Chemotherapy, 50 (1). pp. 88-95. ISSN 0066-4804

Qu, Xioazhong and Khutoryanskiy, Vitaliy V. and Stewart, Ailsa and Rahman, Samina and Papahadjopoulos-Sternberg, Brigitte and Dufès, Christine and McCarthy, Dave and Wilson, Clive G. and Lyons, Robert and Carter, Katharine C. and Schätzlein, Andreas and Uchegbu, Ijeoma F. (2006) Carbohydrate-based micelle clusters which enhance hydrophobic drug bioavailability by up to 1 order of magnitude. Biomacromolecules, 7 (12). pp. 3452-3459. ISSN 1525-7797

Ferro, V.A. and Carter, K.C. (2006) Mucosal immunisation : successful approaches to targeting different tissues. Methods, 38 (2). pp. 61-64. ISSN 1046-2023

Carter, K.C. and Ferro, V.A. and Alexander, J. and Mullen, A. (2006) Translation of an experimental oral vaccine formulation into a commercial product. Methods, 38 (2). pp. 65-68. ISSN 1046-2023

2005

Carter, K.C. and Hutchison, S. and Boitelle, A. and Murray, H.W. and Sundar, S. and Mullen, A. (2005) Sodium stibogluconate resistance in leishmania donovani correlates with greater tolerance to macrophage antileishmanial responses and trivalent antimony therapy. Parasitology, 131 (6). pp. 747-757. ISSN 0031-1820

2004

Ferro, V.A. and Costa, R. and Carter, K.C. and Harvey, M.J. and Waterston, M.M. and Mullen, A. and Matschke, C. and Mann, J.F.S. and Colston, A. and Stimson, W.H. (2004) Immune responses to a GnRH-based anti-fertility immunogen, induced by different adjuvants and subsequent effect on vaccine efficacy. Vaccine, 22 (8). pp. 1024-31. ISSN 1873-2518

Mann, J.F.S. and Ferro, V.A. and Mullen, A. and Tetley, L. and Mullen, M. and Carter, K.C. and Alexander, J. and Stimson, W.H. (2004) Optimisation of a lipid based oral delivery system containing A/Panama influenza haemagglutinin. Vaccine, 22 (19). pp. 2425-2429. ISSN 1873-2518

2003

Nieto, J. and Alvar, J. and Mullen, A. and Carter, K.C. and Rodriguez, C. and San Andres, M.I. and San Andres, M.D. and Baillie, A.J. (2003) Pharmacokinetics, toxicities, and efficacies of sodium stibogluconate formulations after intravenous administration in animals. Antimicrobial Agents and Chemotherapy, 47 (9). pp. 2781-2787. ISSN 0066-4804

Carter, K.C. and Sundar, S. and Spickett, C.M. and Pereira, O.C. and Mullen, A. (2003) The in vivo susceptibility of Leishmania donovani to sodium stibogluconate is drug specific and can be reversed by inhibiting glutathione biosynthesis. Antimicrobial Agents and Chemotherapy, 47 (5). pp. 1529-1535. ISSN 0066-4804

2002

Nic Daeid, N. and Carter, K.C. and Finnon, Y.S. and Waddell, R.J.H. and Robson, D.C. (2002) The effect of nitrostyrene on cell proliferation and macrophage immune responses. Immunopharmacology and Immunotoxicology, 24 (2). pp. 187-197. ISSN 0892-3973

Alexander, James and Brombacher, Frank and McGachy, H.A. and McKenzie, A.N.J. and Walker, W. and Carter, K.C. (2002) An essential role for IL-13 in maintaining a non-healing response following leishmania mexicana infection. European Journal of Immunology, 32 (10). pp. 2923-2933. ISSN 0014-2980

2001

Carter, K.C. and Mullen, A. and Sundar, S. and Kenney, R.T. (2001) Efficacies of vesicular and free sodium stibogluconate formulations against clinical isolates of leishmania donovani. Antimicrobial Agents and Chemotherapy, 45 (12). pp. 355-359. ISSN 0066-4804

2000

Mullen, Alexander and Carter, Katharine; Uchegbu, L F, ed. (2000) Non-ionic surfactant vesicles for the treatment of visceral leishmaniasis. In: Synthetic surfactant vesicles. CRC Press. ISBN 9789058230119