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2023

Topuz Ata, Derya and Hussain, Muattaz and Jones, Michael and Best, Jonathan and Wiese, Martin and Carter, Katharine Christine (2023) Immunisation with transgenic L. tarentolae expressing gamma glutamyl cysteine synthetase from pathogenic Leishmania species protected against L. major and L. donovani infection in a murine model. Microorganisms, 11 (5). 1322. ISSN 2076-2607

2022

Al Kufi, Suad Gazi Jaafer and Emmerson, Josiah and Rosenqvist, Heidi and Garcia, Catarina Mateus Moreira and Rios-Szwed, Diana Onodelia and Wiese, Martin (2022) Absence of DEATH kinesin is fatal for Leishmania mexicana amastigotes. Scientific Reports, 12 (1). 3266. ISSN 2045-2322

2020

Hall, Amy R. and Blakeman, Jamie T. and Eissa, Ahmed M. and Chapman, Paul and Morales-García, Ana L. and Stennett, Laura and Martin, Oihane and Giraud, Emilie and Dockrell, David H. and Cameron, Neil R. and Wiese, Martin and Yakop, Laith and Rogers, Matthew E. and Geoghegan, Mark (2020) Glycan–glycan interactions determine Leishmania attachment to the midgut of permissive sand fly vectors. Chemical Science, 11 (40). pp. 10973-10983. ISSN 2041-6539

2019

Hombach-Barrigah, Antje and Bartsch, Katharina and Smirlis, Despina and Rosenqvist, Heidi and MacDonald, Andrea and Dingli, Florent and Loew, Damarys and Späth, Gerald F. and Rachidi, Najma and Wiese, Martin and Clos, Joachim (2019) Leishmania donovani 90 kD heat shock protein - impact of phosphosites on parasite fitness, infectivity and casein kinase affinity. Scientific Reports, 9 (1). 5074. ISSN 2045-2322

2016

Goldman-Pinkovich, Adele and Balno, Caitlin and Strasser, Rona and Zeituni-Molad, Michal and Bendelak, Keren and Rentsch, Doris and Ephros, Moshe and Wiese, Martin and Jardim, Armando and Myler, Peter J and Zilberstein, Dan (2016) An arginine deprivation response pathway is induced in Leishmania during macrophage invasion. PLOS Pathogens, 12 (4). e1005494. ISSN 1553-7366

2014

Cayla, Mathieu and Rachidi, Najma and Leclercq, Olivier and Schmidt-Arras, Dirk and Rosenqvist, Heidi and Wiese, Martin and Späth, Gerald F (2014) Transgenic analysis of the Leishmania MAP kinase MPK10 reveals an auto-inhibitory mechanism crucial for stage-regulated activity and parasite viability. PLOS Pathogens, 10 (9). e1004347. ISSN 1553-7366

Yau, Wai-Lok and Pescher, Pascale and MacDonald, Andrea and Hem, Sonia and Zander, Dorothea and Retzlaff, Silke and Blisnick, Thierry and Rotureau, Brice and Rosenqvist, Heidi and Wiese, Martin and Bastin, Philippe and Clos, Joachim and Späth, Gerald (2014) The Leishmania donovani chaperone cyclophilin 40 is essential for intracellular infection independent of its stage-specific phosphorylation status. Molecular Microbiology, 93 (1). 80–97. ISSN 0950-382X

2012

Mandal, Goutam and Sharma, Mansi and Kruse, Martin and Sander-Juelch, Claudia and Munro, Laura A and Wang, Yong and Vilg, Jenny Veide and Tamás, Markus J and Bhattacharjee, Hiranmoy and Wiese, Martin and Mukhopadhyay, Rita (2012) Modulation of Leishmania major aquaglyceroporin activity by a mitogen-activated protein kinase. Molecular Microbiology, 85 (6). 1204–1218.

Alsaadi, Manal and Italia, Jagdishbhai Laxmanbhai and Mullen, Alexander and Kumar, M.N.V Ravi and Candlish, A.A. and Williams, Roderick and Shaw, C.D. and Al-Gawhari, Fatima and Coombs, Graham and Wiese, Martin and Thomson, Alison and Puig-Sellart, M. and Wallace, J. and Sharp, A and Wheeler, Lee and Warn, Peter and Carter, Katharine (2012) The efficacy of aerosol treatment with non-ionic surfactant vesicles containing amphotericin B in rodent models of leishmaniasis and pulmonary aspergillosis infection. Journal of Controlled Release, 160 (3). pp. 685-691. ISSN 0168-3659

2010

Lamerz, Anne-Christin and Damerow, Sebastian and Kleczka, Barbara and Wiese, Martin and van Zandbergen, Ger and Lamerz, Jens and Wenzel, Alexander and Hsu, Fong-Fu and Turk, John and Beverley, Stephen M and Routier, Françoise H (2010) Deletion of UDP-glucose pyrophosphorylase reveals a UDP-glucose independent UDP-galactose salvage pathway in Leishmania major. Glycobiology, 20 (7). pp. 872-882.

von Freyend, Simona John and Rosenqvist, Heidi and Fink, Annette and Melzer, Inga Maria and Clos, Joachim and Jensen, Ole Nørregaard and Wiese, Martin (2010) LmxMPK4, an essential mitogen-activated protein kinase of Leishmania mexicana is phosphorylated and activated by the STE7-like protein kinase LmxMKK5. International Journal for Parasitology, 40 (8). pp. 969-978.

2009

Wiese, M. and Morris, Andrew and Grant, Karen M.; Selzer, Paul M., ed. (2009) Trypanosomatid protein kinases as potential drug targets. In: Antiparasitic and Antibacterial Drug Discovery. John Wiley & Sons Inc., pp. 227-276. ISBN 978-3-527-32327-2

2008

Thiel, Meike and Harder, Simone and Wiese, Martin and Kroemer, Manfred and Bruchhaus, Iris (2008) Involvement of a Leishmania thymidine kinase in flagellum formation, promastigote shape and growth as well as virulence. Molecular and Biochemical Parasitology, 158 (2). pp. 152-162. ISSN 0166-6851

2007

Wiese, Martin (2007) Leishmania MAP kinases-familiar proteins in an unusual context. International Journal for Parasitology, 37 (10). pp. 1053-62. ISSN 0020-7519

Kleczka, B. and Lamerz, Anne-Christin and van Zandbergen, G. and Wenzel, Ulf and Gerardy-Schahn, Rita and Wiese, Martin and Routier, Françoise H (2007) Targeted gene deletion of leishmania major UDP-galactopyranose mutase leads to attenuated virulence. Journal of Biological Chemistry, 282 (14). pp. 10498-10505. ISSN 1083-351X

2006

Erdmann, M. and Scholz, M. and Melzer, I.M. and Schmetz, C. and Wiese, M. (2006) Interacting protein kinases involved in the regulation of flagellar length. Molecular Biology of the Cell, 17 (4). pp. 2035-2045. ISSN 1059-1524

2005

Wang, Qiong and Melzer, Inga M and Kruse, Martin and Sander-Juelch, Claudia and Wiese, Martin (2005) LmxMPK4, a mitogen-activated protein (MAP) kinase homologue essential for promastigotes and amastigotes of Leishmania mexicana. Kinetoplastid Biology and Disease, 4. 6. ISSN 1475-9292

Weise, Frank and Thilo, Lutz and Engstler, Markus and Wiese, Martin and Benzel, Isabel and Kühn, Christina and Bühring, Hans-Jörg and Overath, Peter (2005) Binding affinity and capacity of putative adaptor-mediated sorting of a Type I membrane protein in Leishmania mexicana. Molecular and Biochemical Parasitology, 142 (2). pp. 203-11. ISSN 0166-6851

Bengs, F. and Scholz, A. and Kuhn, D. and Wiese, M. (2005) LmxMPK9, a mitogen-activated protein kinase homologue affects flagellar length in leishmania mexicana. Molecular Microbiology, 55 (5). pp. 1606-1615. ISSN 0950-382X

2003

Wiese, Martin and Wang, Qiong and Görcke, Iris (2003) Identification of mitogen-activated protein kinase homologues from Leishmania mexicana. International Journal for Parasitology, 33 (14). pp. 1577-1587. ISSN 0020-7519

Wiese, M. and Kuhn, D. and Grunfelder, C.G. (2003) Protein kinase involved in flagellar-length control. Eukaryotic cell, 2 (4). pp. 769-777. ISSN 1535-9778

2001

Duncan, Robert and Alvarez, R and Jaffe, C L and Wiese, M and Klutch, M and Shakarian, A and Dwyer, D and Nakhasi, H L (2001) Early response gene expression during differentiation of cultured Leishmania donovani. Parasitology Research, 87 (11). pp. 897-906. ISSN 0932-0113

Wiese, M and Görcke, I (2001) Homologues of LMPK, a mitogen-activated protein kinase from Leishmania mexicana, in different Leishmania species. Medical Microbiology and Immunology, 190 (1-2). pp. 19-22. ISSN 0300-8584

2000

Weise, F and Stierhof, Y D and Kühn, C and Wiese, M and Overath, P (2000) Distribution of GPI-anchored proteins in the protozoan parasite Leishmania, based on an improved ultrastructural description using high-pressure frozen cells. Journal of Cell Science, 113 Pt 24. pp. 4587-4603. ISSN 0021-9533

Benzel, I and Weise, F and Wiese, M (2000) Deletion of the gene for the membrane-bound acid phosphatase of Leishmania mexicana. Molecular and Biochemical Parasitology, 111 (1). pp. 77-86. ISSN 0166-6851

Aebischer, T and Wolfram, M and Patzer, S I and Ilg, T and Wiese, M and Overath, P (2000) Subunit vaccination of mice against new world cutaneous leishmaniasis : comparison of three proteins expressed in amastigotes and six adjuvants. Infection and Immunity, 68 (3). pp. 1328-1336. ISSN 0019-9567

1999

Wiese, M and Görcke, I and Overath, P (1999) Expression and species-specific glycosylation of Leishmania mexicana secreted acid phosphatase in Leishmania major. Molecular and Biochemical Parasitology, 102 (2). pp. 325-329. ISSN 0166-6851

1998

Stierhof, Y D and Wiese, M and Ilg, T and Overath, P and Häner, M and Aebi, U (1998) Structure of a filamentous phosphoglycoprotein polymer : the secreted acid phosphatase of Leishmania mexicana. Journal of Molecular Biology, 282 (1). pp. 137-148. ISSN 0022-2836

Wiese, M (1998) A mitogen-activated protein (MAP) kinase homologue of Leishmania mexicana is essential for parasite survival in the infected host. The EMBO journal, 17 (9). pp. 2619-2628. ISSN 1460-2075

1997

Overath, P and Stierhof, Y D and Wiese, M (1997) Endocytosis and secretion in trypanosomatid parasites - Tumultuous traffic in a pocket. Trends in Cell Biology, 7 (1). pp. 27-33. ISSN 0962-8924

1996

Wolfram, M and Fuchs, M and Wiese, M and Stierhof, Y D and Overath, P (1996) Antigen presentation by Leishmania mexicana-infected macrophages : activation of helper T cells by a model parasite antigen secreted into the parasitophorous vacuole or expressed on the amastigote surface. European Journal of Immunology, 26 (12). pp. 3153-3162. ISSN 0014-2980

Wiese, Martin and Berger, Oliver and Stierhof, York-Dieter and Wolfram, Markus and Fuchs, Manuela and Overath, Peter (1996) Gene cloning and cellular localization of a membrane-bound acid phosphatase of Leishmania mexicana. Molecular and Biochemical Parasitology, 82 (2). pp. 153-165. ISSN 0166-6851

1995

Wiese, M and Ilg, T and Lottspeich, F and Overath, P (1995) Ser/Thr-rich repetitive motifs as targets for phosphoglycan modifications in Leishmania mexicana secreted acid phosphatase. The EMBO journal, 14 (6). pp. 1067-1074. ISSN 1460-2075

1994

Ilg, T and Stierhof, Y D and Wiese, M and McConville, M J and Overath, P (1994) Characterization of phosphoglycan-containing secretory products of Leishmania. Parasitology, 108 (S1). S63-71. ISSN 0031-1820

1993

Ilg, Thomas and Harbecke, Dorothee and Wiese, Martin and Overath, Peter (1993) Monoclonal antibodies directed against Leishmania secreted acid phosphatase and lipophosphoglycan. Partial characterization of private and public epitopes. European Journal of Biochemistry, 217 (2). pp. 603-15. ISSN 0014-2956