Leishmania MAP kinases-familiar proteins in an unusual context
Wiese, Martin (2007) Leishmania MAP kinases-familiar proteins in an unusual context. International Journal for Parasitology, 37 (10). pp. 1053-62. ISSN 0020-7519
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Mitogen-activated protein kinases are well-known mediators of signal transduction of higher eukaryotes regulating important processes like proliferation, differentiation, stress response and apoptosis. In Leishmania, the typical three-tiered module of MAP kinase signal transduction pathways is present. However, typical activators like cell surface receptors and substrates such as RNA polymerase II transcription factors are missing. Here, I describe the set of 15 putative mitogen-activated protein kinases encoded in the Leishmania genome and discuss their potential function.
Creators(s): |
Wiese, Martin ![]() | Item type: | Article |
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ID code: | 49450 |
Keywords: | amino acid sequence, animals, gene expression regulation, leishmania, mitogen-activated protein kinases, molecular sequence data, phylogeny, protozoan proteins, signal transduction, deletion analysis, kinetoplastida, Medicine, Immunology, Infectious Diseases, Parasitology |
Subjects: | Medicine Science > Microbiology > Immunology |
Department: | Faculty of Science > Strathclyde Institute of Pharmacy and Biomedical Sciences |
Depositing user: | Pure Administrator |
Date deposited: | 01 Oct 2014 09:56 |
Last modified: | 20 Jan 2021 21:28 |
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URI: | https://strathprints.strath.ac.uk/id/eprint/49450 |
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