Leishmania MAP kinases-familiar proteins in an unusual context

Wiese, Martin (2007) Leishmania MAP kinases-familiar proteins in an unusual context. International Journal for Parasitology, 37 (10). pp. 1053-62. ISSN 0020-7519 (https://doi.org/10.1016/j.ijpara.2007.04.008)

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Abstract

Mitogen-activated protein kinases are well-known mediators of signal transduction of higher eukaryotes regulating important processes like proliferation, differentiation, stress response and apoptosis. In Leishmania, the typical three-tiered module of MAP kinase signal transduction pathways is present. However, typical activators like cell surface receptors and substrates such as RNA polymerase II transcription factors are missing. Here, I describe the set of 15 putative mitogen-activated protein kinases encoded in the Leishmania genome and discuss their potential function.

ORCID iDs

Wiese, Martin ORCID logoORCID: https://orcid.org/0000-0003-4493-0835;
  • Item type:Article
    ID code:49450
    Dates:
    Date
    Event
    August 2007
    Published
    29 April 2007
    Published Online
    18 April 2007
    Accepted
    Keywords:amino acid sequence, animals, gene expression regulation, leishmania, mitogen-activated protein kinases, molecular sequence data, phylogeny, protozoan proteins, signal transduction, deletion analysis, kinetoplastida, Medicine, Immunology, Infectious Diseases, Parasitology, SDG 3 - Good Health and Well-being
    Subjects:Medicine
    Science > Microbiology > Immunology
    Department:Faculty of Science > Strathclyde Institute of Pharmacy and Biomedical Sciences
    Depositing user: Pure Administrator
    Date deposited:01 Oct 2014 09:56
    Last modified:15 Sep 2021 17:03
    Related URLs:
    URI:https://strathprints.strath.ac.uk/id/eprint/49450
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