Picture of mobile phone running fintech app

Fintech: Open Access research exploring new frontiers in financial technology

Strathprints makes available Open Access scholarly outputs by the Department of Accounting & Finance at Strathclyde. Particular research specialisms include financial risk management and investment strategies.

The Department also hosts the Centre for Financial Regulation and Innovation (CeFRI), demonstrating research expertise in fintech and capital markets. It also aims to provide a strategic link between academia, policy-makers, regulators and other financial industry participants.

Explore all Strathclyde Open Access research...

The isolation of antiprotozoal compounds from Libyan propolis

Siheri, Weam and Igoli, John O. and Gray, Alexander I. and Nasciemento, Ticiano G. and Zhang, Tong and Fearnley, James and Clements, Carol J. and Carter, Katharine C. and Carruthers, John and Edrada-Ebel, RuAngelie and Watson, David G. (2014) The isolation of antiprotozoal compounds from Libyan propolis. Phytotherapy Research, 28 (12). 1756–1760. ISSN 0951-418X

[img]
Preview
Text (Siheri-etal-PR-2014-The-isolation-of-anti-protozoal-compounds-from-Libyan)
Siheri_etal_PR_2014_The_isolation_of_anti_protozoal_compounds_from_Libyan.pdf
Accepted Author Manuscript

Download (560kB) | Preview

Abstract

Propolis is increasingly being explored as a source of biologically active compounds. Until now, there has been no study of Libyan propolis. Two samples were collected in North East Libya and tested for their activity against Trypanosoma brucei. Extracts from both samples had quite high activity. One of the samples was fractionated and yielded a number of active fractions. Three of the active fractions contained single compounds, which were found to be 13-epitorulosal, acetyl-13-epi-cupressic acid and 13-epi-cupressic acid, which have been described before in Mediterranean propolis. Two of the compounds had a minimum inhibitory concentration value of 1.56 µg/mL against T. brucei. The active fractions were also tested against macrophages infected with Leishmania donovani, and again moderate to strong activity was observed with the compounds having IC50 values in the range 5.1-21.9 µg/mL.