Browse by Author or creator
2023
Al-Tannak, Naser F. and Al Ali, Abdullah and Santali, Eman Y. and Clements, C. J. and Gray, A. I. and Igoli, J. O. (2023) A new isoflavone from Lomariopsis guineensis (Underw.) Alston. Emirates Journal of Food and Agriculture, 35 (4). pp. 305-310. ISSN 2079-0538
2020
Mazlan, Noor Wini and Clements, Carol and Edrada-Ebel, RuAngelie (2020) Targeted isolation of anti-trypanosomal naphthofuran-quinone compounds from the mangrove plant Avicennia lanata. Marine Drugs, 18 (12). 661. ISSN 1660-3397
Mazlan, Noor Wini and Tate, Rothwelle and Yusoff, Yusnaini Md. and Clements, Carol and Edrada-Ebel, RuAngelie (2020) Metabolomics-guided isolation of anti-trypanosomal compounds from endophytic fungi of the mangrove plant Avicennia lanata. Current Medicinal Chemistry, 27 (11). pp. 1815-1835. ISSN 0929-8673
2019
do Nascimento, Ticiano Gomes and dos Santos Arruda, Rodolfo Elleson and da Cruz Almeida, Erika Tayse and dos Santos Oliveira, José Marcos and Basílio-Júnior, Irinaldo Diniz and Celerino de Moraes Porto, Isabel Cristina and Rodrigues Sabino, Adilson and Tonholo, Josealdo and Gray, Alexander and Edrada Ebel, RuAngelie and Clements, Carol and Zhang, Tong and Watson, David George (2019) Comprehensive multivariate correlations between climatic effect, metabolite-profile, antioxidant capacity and antibacterial activity of Brazilian red propolis metabolites during seasonal study. Scientific Reports, 9. pp. 1-16. 18293. ISSN 2045-2322
Tawfike, Ahmed F. and Romli, Muhammad and Clements, Carol and Abbott, Gráinne and Young, Louise and Schumacher, Marc and Diederich, Marc and Farag, Mohamed and Edrada-Ebel, RuAngelie (2019) Isolation of anticancer and anti-trypanosome secondary metabolites from the endophytic fungus Aspergillus flocculus via bioactivity guided isolation and MS based metabolomics. Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences, 1106-1107. pp. 71-83. ISSN 1570-0232
2017
Omar, Ruwida and Igoli, John O. and Zhang, Tong and Gray, Alexander I. and Ebiloma, Godwin Unekwuojo and Clements, Carol J. and Fearnley, James and Edrada Ebel, RuAngelie and Paget, Tim and de Koning, Harry P. and Watson, David G. (2017) The chemical characterization of Nigerian propolis samples and their activity against Trypanosoma brucei. Scientific Reports, 7 (1). 01038. ISSN 2045-2322
Alonezi, Sanad and Tusiimire, Jonans and Wallace, Jennifer and Dufton, Mark J. and Parkinson, John A. and Young, Louise C. and Clements, Carol J. and Park, Jin-Kyu and Jeon, Jong-Woon and Ferro, Valerie A. and Watson, David G. (2017) Metabolomic profiling of the synergistic effects of melittin in combination with cisplatin on ovarian cancer cells. Metabolites, 7 (14). pp. 1-18. ISSN 2218-1989
2016
Kamal, Nurkhalida and Viegelmann, Christina V. and Clements, Carol J. and Edrada-Ebel, RuAngelie (2016) Metabolomics-guided isolation of anti-trypanosomal metabolites from the endophytic fungus Lasiodiplodia theobromae. Planta Medica. ISSN 0032-0943
Alonezi, Sanad and Tusiimire, Jonans and Wallace, Jennifer and Dufton, Mark J. and Parkinson, John A. and Young, Louise C. and Clements, Carol J. and Park, Jin Kyu and Jeon, Jong Woon and Ferro, Valerie A. and Watson, David G. (2016) Metabolomic profiling of the effects of melittin on cisplatin resistant and cisplatin sensitive ovarian cancer cells using mass spectrometry and biolog microarray technology. Metabolites, 6 (4). ISSN 2218-1989
Siheri, Weam and Zhang, Tong and Ebiloma, Godwin Unekwuojo and Biddau, Marco and Woods, Nicola and Hussain, Muattaz Yassein and Clements, Carol J. and Fearnley, James and Edrada Ebel, RuAngelie and Paget, Timothy and Müller, Sylke and Carter, Katharine C. and Ferro, Valerie A. and De Koning, Harry P. and Watson, David G. (2016) Chemical and antimicrobial profiling of propolis from different regions within Libya. PLOS One, 11 (5). e0155355. ISSN 1932-6203
Tusiimire, Jonans and Wallace, Jennifer and Woods, Nicola and Dufton, Mark J. and Parkinson, John A. and Abbott, Grainne and Clements, Carol J. and Young, Louise and Park, Jin Kyu and Jeon, Jong Woon and Ferro, Valerie A. and Watson, David G. (2016) Effect of bee venom and its fractions on the release of pro-inflammatory cytokines in PMA-differentiated U937 cells co-stimulated with LPS. Vaccines, 4 (2). 11. ISSN 2076-393X
Omar, Ruwida M K and Igoli, John and Gray, Alexander I and Ebiloma, Godwin Unekwuojo and Clements, Carol and Fearnley, James and Edrada Ebel, Ru Angeli and Zhang, Tong and De Koning, Harry P and Watson, David G (2016) Chemical characterisation of Nigerian red propolis and its biological activity against Trypanosoma Brucei. Phytochemical Analysis, 27 (2). 107–115. ISSN 0958-0344
Wan-Mohtar, Wan Abd Al Qadr Imad and Young, Louise and Abbott, Gráinne M. and Clements, Carol and Harvey, Linda M. and McNeil, Brian (2016) Antimicrobial properties and cytotoxicity of sulfated (1,3)-β-D-glucan from the mycelium of the mushroom Ganoderma lucidum. Journal of Microbiology and Biotechnology, 26 (6). pp. 999-1010. ISSN 1738-8872
Kamal, Nurkhalida and Clements, Carol and Gray, Alexander I. and Edrada-Ebel, RuAngelie (2016) Anti-infective activities of secondary metabolites from Vitex pinnata. Journal of Applied Pharmaceutical Science, 6 (1). pp. 102-106. ISSN 2231-3354
2014
Siheri, Weam and Igoli, John O. and Gray, Alexander I. and Nasciemento, Ticiano G. and Zhang, Tong and Fearnley, James and Clements, Carol J. and Carter, Katharine C. and Carruthers, John and Edrada-Ebel, RuAngelie and Watson, David G. (2014) The isolation of antiprotozoal compounds from Libyan propolis. Phytotherapy Research, 28 (12). 1756–1760. ISSN 1099-1573
Tawfike, Ahmed Fares and Edrada-Ebel, Ruangelie and Tate, Roth and Diederich, Marc and Schumacher, Marc and Sawadogo, Richard and Clements, Carol and Young, Louise (2014) Metabolomics and dereplication studies of endophytic metabolites from some Egyptian medicinal plants in the search potential antimicrobial drugs. In: Metabolomics 2014, 2014-06-23 - 2014-06-26, Daiichi Hotel Tsuruoka and Marica/Washington Hotel.
Viegelmann, Christina and Parker, Jennifer and Ooi, Thengtheng and Clements, Carol and Abbott, Gráinne and Young, Louise and Kennedy, Jonathan and Dobson, Alan D W and Edrada-Ebel, RuAngelie (2014) Isolation and identification of antitrypanosomal and antimycobacterial active steroids from the sponge haliclona simulans. Marine Drugs, 12 (5). pp. 2937-2952. ISSN 1660-3397
Zhang, Tong and Omar, Ruwida and Siheri, Weam and Al Mutairi, Sultan and Clements, Carol and Fearnley, James and Edrada-Ebel, Ruangelie and Watson, David (2014) Chromatographic analysis with different detectors in the chemical characterisation and dereplication of African propolis. Talanta, 120. pp. 181-190. ISSN 0039-9140
Lang, Stuart and Khalaf, Abedawn I and Breen, David and Huggan, Judith and Clements, Carol and MacKay, Simon and Suckling, Colin (2014) Oligoamides of 2-amino-5-alkylthiazole 4-carboxylic acids : anti-trypanosomal compounds. Medicinal Chemistry Research, 23 (3). pp. 1170-1179.
Rashid, Mamoon-Ur and Ali, Saqib and Alamzeb, Muhammad and Igoli, John and Clements, Carol and Shah, SQ and Ferro, Valerie and Gray, Alexander and Khan, M Rafiullah (2014) Phytochemical and antitrypanosomal investigation of the fractions and compounds isolated from Artemesia elegantissima. Pharmaceutical Biology, 52 (8). pp. 983-987. ISSN 1388-0209
2013
Noor Wini Binti Mazlan, N and Tate, Rothwelle and Clements, Carol and Edrada-Ebel, Ruangelie (2013) Metabolomics studies of endophytic metabolites from Malaysian mangrove plant in the search for new potential antibiotics. Planta Medica, 79 (13). PA22. ISSN 0032-0943
Elmezughi, Jamal and Shittu, Hafsat and Clements, Carol and Edrada-Ebel, Ru Angelie and Seidel, Veronique and Gray, Alexander (2013) Bioactive natural compounds from Prosopis africana and Abies nobili. Journal of Applied Pharmaceutical Science, 3 (3). pp. 40-43.
Viegelmann, Christina Victoria and Hoe Leong, Cheung and Clements, Carol and Abdelmohsen, Usama Ramada and Hentschel, Ute and Margassery, Lekha Menon and Kennedy, Jonathan and Perrocco, Dominick and Dobson, Alan D. W. and Edrada-Ebel, Ruangelie (2013) Metabolomics as a tool in the identification and production of new antibiotics from sponges and endosymbiotic bacteria. In: 6th International Conference on Marine Bioprospecting (BIOPROSP_13), 2013-02-20 - 2013-02-22.
Ali, Saqib and Igoli, John and Clements, Carol and Semaan, Dima and Almazeb, Muhammad and Rashid, Mamoon-Ur and Shah, Syed Qaisar and Ferro, Valerie and Gray, Alexander and Khan, M Rafiullah (2013) Antidiabetic and antimicrobial activities of fractions and compounds isolated from Berberis brevissima Jafri and Berberis parkeriana Schneid. Bangladesh Journal of Pharmacology, 8 (3). pp. 336-342.
Elmezughi, Jamal and Clements, Carol and Seidel, Veronique and Gray, Alexander (2013) Trypanocidal active compounds from Scottish Abies nobilis and Pinus sylvestris. International Research Journal of Pharmacy, 4 (2). pp. 56-59.
Gebruers, Evelien and Cordero-Maldonado, María Lorena and Gray, Alexander I and Clements, Carol and Harvey, Alan L and Edrada-Ebel, Ruangelie and de Witte, Peter A M and Crawford, Alexander D and Esguerra, Camila V (2013) A phenotypic screen in zebrafish identifies a novel small-molecule inducer of ectopic tail formation suggestive of alterations in non-canonical Wnt/PCP signaling. PLOS One, 8 (12). e83293. ISSN 1932-6203
2012
Clark, Rachel L. and Clements, Carol J. and Barrett, Michael P. and Mackay, Simon P. and Rathnam, Rajendra P. and Owusu-Dapaah, George and Spencer, John and Huggan, Judith K. (2012) Identification and development of the 1,4-benzodiazepin-2-one and quinazoline-2,4-dione scaffolds as submicromolar inhibitors of HAT. Bioorganic and Medicinal Chemistry, 20 (20). pp. 6019-6033. ISSN 0968-0896
Igoli, N. P. and Obanu, Z. A. and Gray, A. I. and Clements, C. (2012) Bioactive diterpenes and sesquiterpenes from the rhizomes of Wild ginger (Siphonochilus aethiopicus (Schweinf) B.L Burtt). African Journal of Traditional, Complementary, and Alternative Medicines, 9 (1). pp. 88-93. ISSN 0189-6016
Khalaf, Abedawn and Bourdin, Claire and Breen, David and Donoghue, Gavin and Scott, Fraser and Suckling, Colin and MacMillan, Donna and Clements, Carol and Fox, Keith and Sekibo, Doreen (2012) Design, synthesis and antibacterial activity of minor groove binders: the role of non-cationic tail groups. European Journal of Medicinal Chemistry, 56. pp. 39-47. ISSN 0223-5234
2011
Gray, Alexander and Igoli, John and Clements, Carol and Mouad, Hazar; Rasooli, Iraj, ed. (2011) Anti-trypanosomal activity and cytotoxicity of some compounds and extracts from Nigerian medicinal plants. In: Phytochemicals. InTech, pp. 375-399. ISBN 9789533074245
Spencer, John and Rathnam, Rajendra P. and Harvey, Alan L. and Clements, Carol J. and Clark, Rachel L. and Barrett, Michael P. and Wong, Pui Ee and Male, Louise and Coles, Simon J. and Mackay, Simon P. (2011) Synthesis and biological evaluation of 1,4-benzodiazepin-2-ones with antitrypanosomal activity. Bioorganic and Medicinal Chemistry, 19 (5). pp. 1802-1815.
Kamal, Nurkhalida Binti and Clements, Carol and Gray, Alexander and Edrada-Ebel, Ruangelie (2011) Discovery of bioactive metabolites from the leaves of Vitex pinnata using high-throughput flash chromatography. Planta Medica, 77 (12). p. 1348. PG68. ISSN 0032-0943
Aly, Amal H and Debbab, Abdessamad and Clements, Carol and Edrada-Ebel, Ruangelie and Orlikova, Barbora and Diederich, Marc and Wray, Victor and Lin, Wenhan and Proksch, Peter (2011) NF kappa B inhibitors and antitrypanosomal metabolites from endophytic fungus Penicillium sp. isolated from Limonium tubiflorum. Bioorganic and Medicinal Chemistry, 19 (1). pp. 414-21.
2010
Kumlung, Tantima and Zhang, Tong and Clements, Carol and Edrada-Ebel, Ruangelie (2010) Metabolomic profiling of some British Isles marine sponges by HR-FTMS and -NMR through differential expression analysis. In: Gordon Research Conference on Marine Natural Products, 2010-02-28 - 2010-03-05, Ventura Beach Marriott. (Unpublished)
2009
Gibson, Colin L. and Huggan, J.K. and Kennedy, Alan and Kiefer, L. and Lee, Jeong Hwan and Suckling, C.J. and Clements, Caorl J. and Harvey, Alan L. and Hunter, William N. and Tulloch, Lindsay B. (2009) Diversity oriented syntheses of fused pyrimidines designed as potential antifolates. Organic and Biomolecular Chemistry, 7 (9). pp. 1829-1842. ISSN 1477-0520
Wheate, N.J. and Abbott, Grainne M. and Tate, Rothwelle J. and Clements, Caorl J. and Edrada-Ebel, RuAngelie and Johnston, B.F. (2009) Side-on binding of p-sulphonatocalix[4]arene to the dinuclear platinum complex trans-[{PtCl(NH3)2}2μ-dpzm]2+ and its implications for anticancer drug delivery. Journal of Inorganic Biochemistry, 103 (3). pp. 448-454. ISSN 0162-0134