Browse by Journal or other publication

2021

Ali, Eslam M.H and El-Telbany, Rania Farag A. and Abdel-Maksoud, Mohammed S. and Ammar, Usama M. and Mersal, Karim I. and Zaraei, Sayed-Omar and El-Gamal, Mohammed I. and Choi, Se-In and Lee, Kyung-Tae and Kim, Hee-Kwon and Lee, Kwan Hyi and Oh, Chang-Hyun (2021) Design, synthesis, biological evaluation, and docking studies of novel (imidazol-5-yl)pyrimidine-based derivatives as dual BRAFV600E/p38α inhibitors. European Journal of Medicinal Chemistry, 215. 113277. ISSN 0223-5234

2020

Lippa, Rhys A. and Barrett, John and Pal, Sandeep and Rowedder, James E. and Murphy, John A. and Barrett, Tim N. (2020) Discovery of the first potent and selective αvβ5 integrin inhibitor based on an amide-containing core. European Journal of Medicinal Chemistry, 208. 112719. ISSN 0223-5234

2019

Hussein, Buthaina and Ikhmais, Balqis and Kadirvel, Manikandan and Magwaza, Rachael N. and Halbert, Gavin and Bryce, Richard A. and Stratford, Ian J. and Freeman, Sally (2019) Discovery of potent 4-aminoquinoline hydrazone inhibitors of NRH:quinoneoxidoreductase-2 (NQO2). European Journal of Medicinal Chemistry, 182. 111649. ISSN 0223-5234

2018

Ahonen, Tiina J. and Rinne, Maiju and Grutschreiber, Peter and Mätlik, Kert and Airavaara, Mikko and Schaarschmidt, Dieter and Lang, Heinrich and Reiss, David and Xhaard, Henri and Gavériaux-Ruff, Claire and Yli-Kauhaluoma, Jari and Moreira, Vânia M. (2018) Synthesis of 7β-hydroxy-8-ketone opioid derivatives with antagonist activity at the mu- and delta- opioid receptors. European Journal of Medicinal Chemistry, 151. pp. 495-507. ISSN 0223-5234

Figueiredo, Joana and Serrano, João L. and Cavalheiro, Eunice and Keurulainen, Leena and Yli-Kauhaluoma, Jari and Moreira, Vânia M. and Ferreira, Susana and Domingues, Fernanda C. and Silvestre, Samuel and Almeida, Paulo (2018) Trisubstituted barbiturates and thiobarbiturates : synthesis and biological evaluation as xanthine oxidase inhibitors, antioxidants, antibacterial and antiproliferative agents. European Journal of Medicinal Chemistry, 143. pp. 829-842. ISSN 0223-5234

2017

Scott, Fraser and Nichol, Ryan J.O. and Khalaf, Abedawn I. and Giordani, Federica and Gillingwater, Kirsten and Ramu, Soumya and Elliott, Alysha and Zuegg, Johannes and Duffy, Paula and Rosslee, Michael-Jon and Hlaka, Lerato and Kumar, Santosh and Ozturk, Mumin and Brombacher, Frank and Barrett, Michael and Guler, Reto and Suckling, Colin J. (2017) An evaluation of minor groove binders as anti-fungal and anti-mycobacterial therapeutics. European Journal of Medicinal Chemistry, 136. pp. 561-572. ISSN 0223-5234

2016

Scott, Fraser J. and Khalaf, Abedawn I. and Giordani, Federica and Wong, Pui Ee and Duffy, Sandra and Barrett, Michael and Avery, Vicky M. and Suckling, Colin J. (2016) An evaluation of minor groove binders as anti-Trypanosoma brucei brucei therapeutics. European Journal of Medicinal Chemistry, 116. pp. 116-125. ISSN 0223-5234

Shukla, Lena and Ajram, Laura A. and Begg, Malcolm and Evans, Brian and Graves, Rebecca H. and Hodgson, Simon T. and Lynn, Sean M. and Miah, Afjal H. and Percy, Jonathan M. and Procopiou, Panayiotis A. and Richards, Stephen A. and Slack, Robert J. (2016) 2,8-Diazaspiro[4.5]decan-8-yl)pyrimidin-4-amine potent CCR4 antagonists capable of inducing receptor endocytosis. European Journal of Medicinal Chemistry, 115. pp. 14-25. ISSN 0223-5234

2012

Abualhasan, Murad N. and Good, James A. D. and Wittayanarakul, Kitiyaporn and Anthony, Nahoum G. and Berretta, Giacomo and Rath, Oliver and Kozielski, Frank and Sutcliffe, Oliver B. and Mackay, Simon P. (2012) Doing the methylene shuffle - further insights into the inhibition of mitotic kinesin Eg5 with S-trityl L-cysteine. European Journal of Medicinal Chemistry, 54. pp. 483-498. ISSN 0223-5234

Khalaf, Abedawn and Bourdin, Claire and Breen, David and Donoghue, Gavin and Scott, Fraser and Suckling, Colin and MacMillan, Donna and Clements, Carol and Fox, Keith and Sekibo, Doreen (2012) Design, synthesis and antibacterial activity of minor groove binders: the role of non-cationic tail groups. European Journal of Medicinal Chemistry, 56. pp. 39-47. ISSN 0223-5234

2011

Khalaf, Abedawn I and Anthony, Nahoum and Breen, David and Donoghue, Gavin and Mackay, Simon P and Scott, Fraser J and Suckling, Colin J (2011) Amide isosteres in structure-activity studies of antibacterial minor groove binders. European Journal of Medicinal Chemistry, 46 (11). pp. 5343-5355.

2009

Bansal, R. and Kumar, G. and Gandhi, D. and Young, Louise C. and Harvey, A.L. (2009) Synthesis of a series of 8-(substituted-phenyl)xanthines and a study on the effects of substitution pattern of phenyl substituents on affinity for adenosine A(1) and A(2A) receptors. European Journal of Medicinal Chemistry, 44 (5). pp. 2122-2127. ISSN 0223-5234

2002

Jindal, D.P. and Piplani, P. and Fajrak, H. and Prior, C.B. and Marshall, I.G. (2002) Synthesis and neuromuscular blocking activity of 16beta-n-methylpiperazino steroidal derivatives. European Journal of Medicinal Chemistry, 37 (11). pp. 901-908. ISSN 0223-5234

2001

Jindal, D.P. and Piplani, P. and Fajrak, H. and Prior, C.B. and Marshall, I.G. (2001) Synthesis and neuromuscular blocking activity of 16β-piperidinosteroidal derivatives. European Journal of Medicinal Chemistry, 36 (2). pp. 195-202. ISSN 0223-5234