Browse by Author or creator

2024

Riley, Christopher and Ammar, Usama and Alsfouk, Aisha and Anthony, Nahoum G. and Baiget, Jessica and Berretta, Giacomo and Breen, David and Huggan, Judith and Lawson, Christopher and McIntosh, Kathryn and Plevin, Robin and Suckling, Colin J. and Young, Louise C. and Paul, Andrew and Mackay, Simon P. (2024) Design and synthesis of novel aminoindazole-pyrrolo[2,3-b]pyridine inhibitors of IKKα that selectively perturb cellular non-canonical NF-κB signalling. Molecules, 29 (15). 3515. ISSN 1420-3049

2021

Akil, Lina and Breen, David and Ford, Steven (2021) Design and use of digital mimics for remote learning. In: Analytical Research Forum 2021, 2021-06-15 - 2021-06-16, Online.

2019

Breen, D. and Boyter, A.C. and Lynas, G. (2019) Gamification in M.Pharm. teaching. Pharmacy Education, 19 (1). p. 265. 38. ISSN 1560-2214

Breen, D. and Boyter, A.C. and Lynas, G. (2019) Pharmopoly : gamification in MPharm teaching. In: 2019 Pharmacy Education Conference, University of Manchester, 2019-06-24 - 2019-06-24, University of Manchester.

2017

Anthony, Nahoum G. and Baiget, Jessica and Berretta, Giacomo and Boyd, Marie and Breen, David and Edwards, Joanne and Gamble, Carly and Gray, Alexander I. and Harvey, Alan L. and Hatziieremia, Sophia and Ho, Ka Ho and Huggan, Judith K. and Lang, Stuart and Llona-Minguez, Sabin and Luo, Jia Lin and McIntosh, Kathryn and Paul, Andrew and Plevin, Robin J. and Robertson, Murray N. and Scott, Rebecca and Suckling, Colin J. and Sutcliffe, Oliver Brook and Young, Louise C. and MacKay, Simon P. (2017) Inhibitory Kappa B kinase α (IKKα) inhibitors that recapitulate their selectivity in cells against isoform-related biomarkers. Journal of Medicinal Chemistry, 60 (16). pp. 7043-7066. ISSN 0022-2623

2014

Lang, Stuart and Khalaf, Abedawn I and Breen, David and Huggan, Judith and Clements, Carol and MacKay, Simon and Suckling, Colin (2014) Oligoamides of 2-amino-5-alkylthiazole 4-carboxylic acids : anti-trypanosomal compounds. Medicinal Chemistry Research, 23 (3). pp. 1170-1179.

2012

Khalaf, Abedawn and Bourdin, Claire and Breen, David and Donoghue, Gavin and Scott, Fraser and Suckling, Colin and MacMillan, Donna and Clements, Carol and Fox, Keith and Sekibo, Doreen (2012) Design, synthesis and antibacterial activity of minor groove binders: the role of non-cationic tail groups. European Journal of Medicinal Chemistry, 56. pp. 39-47. ISSN 0223-5234

2011

Khalaf, Abedawn I and Anthony, Nahoum and Breen, David and Donoghue, Gavin and Mackay, Simon P and Scott, Fraser J and Suckling, Colin J (2011) Amide isosteres in structure-activity studies of antibacterial minor groove binders. European Journal of Medicinal Chemistry, 46 (11). pp. 5343-5355.

2009

Anthony, N.G. and Breen, D. and Donoghue, G. and Khalaf, A.I. and Mackay, S.P. and Parkinson, J.A. and Suckling, C.J. (2009) A new synthesis of alkene-containing minor-groove binders and essential hydrogen bonding in binding to DNA and in antibacterial activity. Organic and Biomolecular Chemistry, 7 (9). pp. 1843-1850. ISSN 1477-0520

Breen, D. and Kennedy, A.R. and Suckling, C.J. (2009) A divergent synthesis of minor groove binders with tail group variation. Organic and Biomolecular Chemistry, 7 (1). pp. 178-186. ISSN 1477-0520

2007

Anthony, Nahoum Guillaume Hsuan and Breen, D. and Clarke, Joanna and Donoghue, Gavin and Drummond, Allan J. and Ellis, Elizabeth and Gemmell, Curtis G. and Helesbeux, Jean-Jacques and Hunter, Iain. S. and Khalaf, Abedawn and MacKay, Simon and Parkinson, J.A. and Suckling, C.J. and Waigh, R.D. (2007) Antimicrobial lexitropsins containing amide, amidine, and alkene linking groups. Journal of Medicinal Chemistry, 50 (24). pp. 6116-6125. ISSN 0022-2623