Browse by Author or creator
2024
Riley, Christopher and Ammar, Usama and Alsfouk, Aisha and Anthony, Nahoum G. and Baiget, Jessica and Berretta, Giacomo and Breen, David and Huggan, Judith and Lawson, Christopher and McIntosh, Kathryn and Plevin, Robin and Suckling, Colin J. and Young, Louise C. and Paul, Andrew and Mackay, Simon P. (2024) Design and synthesis of novel aminoindazole-pyrrolo[2,3-b]pyridine inhibitors of IKKα that selectively perturb cellular non-canonical NF-κB signalling. Molecules, 29 (15). 3515. ISSN 1420-3049
McIntosh, Kathryn (2024) Advanced Immunology by the University of Strathclyde, Glasgow. Free Press Journal. pp. 14-23.
2023
McIntosh, Kathryn (2023) Beyond the Vaccine. The Hindu (Education Plus). p. 2.
McIntosh, Kathryn and Khalaf, Yousif H. and Craig, Rachel and West, Christopher and McCulloch, Ashley and Waghmare, Ajay and Lawson, Christopher and Chan, Edmond Y.W. and MacKay, Simon and Paul, Andrew and Plevin, Robin (2023) IL-1β stimulates a novel, IKKα -dependent, NIK -independent activation of non-canonical NFκB signalling. Cellular Signalling, 107. 110684. ISSN 1873-3913
2020
McIntosh, Kathryn A. and Cunningham, Margaret R. and Bushell, Trevor and Plevin, Robin (2020) The development of proteinase-activated receptor-2 modulators and the challenges involved. Biochemical Society Transactions, 48 (6). pp. 2525-2537. BST20200191. ISSN 0300-5127
2019
Schroeder, Juliane and Ross, Kirsty and McIntosh, Kathryn and Jabbar, Shilan Khayrula Jabbar and Woods, Stuart and Crowe, Jenny and Patterson-Kane, Janet C and Alexander, James and Lawrence, Catherine and Plevin, Robin (2019) Novel protective role for MAP kinase phosphatase 2 in inflammatory arthritis. RMD Open, 5 (1). e000711. e000711. ISSN 2056-5933
2018
Ng, Pei Y. and McIntosh, Kathryn A. and Hargrave, Gillian and Ho, Ka H. and Paul, Andrew and Plevin, Robin (2018) Inhibition of cytokine-mediated JNK signalling by purinergic P2Y11 receptors, a novel protective mechanism in endothelial cells. Cellular Signalling, 51. pp. 59-71. ISSN 1873-3913
2017
Anthony, Nahoum G. and Baiget, Jessica and Berretta, Giacomo and Boyd, Marie and Breen, David and Edwards, Joanne and Gamble, Carly and Gray, Alexander I. and Harvey, Alan L. and Hatziieremia, Sophia and Ho, Ka Ho and Huggan, Judith K. and Lang, Stuart and Llona-Minguez, Sabin and Luo, Jia Lin and McIntosh, Kathryn and Paul, Andrew and Plevin, Robin J. and Robertson, Murray N. and Scott, Rebecca and Suckling, Colin J. and Sutcliffe, Oliver Brook and Young, Louise C. and MacKay, Simon P. (2017) Inhibitory Kappa B kinase α (IKKα) inhibitors that recapitulate their selectivity in cells against isoform-related biomarkers. Journal of Medicinal Chemistry, 60 (16). pp. 7043-7066. ISSN 0022-2623
2016
Cunningham, Margaret and McIntosh, Kathryn and Bushell, Trevor and Sloan, Graeme and Plevin, Robin (2016) Proteinase-activated receptors (PARs) as targets for antiplatelet therapy. Biochemical Society Transactions, 44 (2). pp. 606-612. ISSN 0300-5127
Bushell, Trevor J. and Cunningham, Margaret R. and McIntosh, Kathryn A. and Moudio, Serge and Plevin, Robin (2016) Protease-activated receptor 2 : are common functions in glial and immune cells linked to inflammation-related CNS disorders? Current Drug Targets, 17 (16). pp. 1861-1870. ISSN 1873-5592
2015
Huesa, Carmen and Ortiz, Ana C and Dunning, Lynette and McGavin, Laura and Bennett, Louise and McIntosh, Kathryn and Crilly, Anne and Kurowska-Stolarska, Mariola and Plevin, Robin and van ,t Hof, Rob J and Rowan, Andrew D and McInnes, Iain B and Goodyear, Carl S and Lockhart, John C and Ferrell, William R (2015) Proteinase-activated receptor 2 modulates OA-related pain, cartilage and bone pathology. Annals of the Rheumatic Diseases. ISSN 0003-4967
2012
Cunningham, Margaret R. and McIntosh, Kathryn A. and Pediani, John D. and Robben, Joris and Cooke, Alexandra E. and Nilsson, Mary and Gould, Gwyn W. and Mundell, Stuart and Milligan, Graeme and Plevin, Robin (2012) Novel role for proteinase-activated receptor 2 (PAR2) in membrane trafficking of proteinase-activated receptor 4 (PAR4). Journal of Biological Chemistry, 287 (20). pp. 16656-16669. ISSN 1083-351X
2011
Gamble, Carly and McIntosh, Kathryn and Scott, Rebecca and Ho, Ka Ho and Plevin, Robin and Paul, Andrew (2011) Inhibitory kappa B kinases as targets for pharmacological regulation. British Journal of Pharmacology, 165 (4). 802–819. ISSN 1476-5381
2010
McIntosh, K. and Cunningham, M.R. and Cadalbert, L. and Lochart, J. and Boyd, G. and Ferrell, W.R. and Plevin, R.J. (2010) Proteinase-activated receptor-2 mediated inhibition of TNFα-stimulated JNK activation — A novel paradigm for Gq/11 linked GPCRs. Cellular Signalling, 22 (2). pp. 265-273. ISSN 1873-3913
2007
McIntosh, Kathryn A and Plevin, Robin and Ferrell, William R and Lockhart, John C (2007) The therapeutic potential of proteinase-activated receptors in arthritis. Current Opinion in Pharmacology, 7 (3). pp. 334-338. ISSN 1471-4892