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2024

Buckley, Charlotte and Lee, Matthew D. and Zhang, Xun and Wilson, Calum and McCarron, John G. (2024) Signalling switches maintain intercellular communication in the vascular endothelium : endothelial Ca2+ waves driven by regenerative IP3-induced IP3 production. British Journal of Pharmacology, 181 (16). pp. 2810-2832. ISSN 1476-5381

Dignam, Joshua P. and Sharma, Smriti and Stasinopoulos, Ioannis and MacLean, Margaret R. (2024) Pulmonary arterial hypertension : sex matters. British Journal of Pharmacology, 181 (7). pp. 938-966. ISSN 1476-5381

Guilding, Clare and White, Paul J. and Cunningham, Margaret and Kelly-Laubscher, Roisin and Koenig, Jennifer and Babey, Anna Marie and Tucker, Steve and Kelly, John P. and Gorman, Laurel and Aronsson, Patrik and Hawes, Martin and Ngo, Suong N.T. and Mifsud, Janet and Werners, Arend H. and Hinton, Tina and Khan, Fouzia and Aljofan, Mohamad and Angelo, Tom (2024) Defining and unpacking the core concepts of pharmacology : a global initiative. British Journal of Pharmacology, 181 (3). pp. 375-392. ISSN 1476-5381

2023

White, Paul and Guilding, Clare and Angelo, Tom and Kelly, John and Gorman, Laurel and Tucker, Steve and Fun, Ashleigh and Han, Jae and Chen, Guanliang and Samak, Yassmin and Babey, Anna-Marie and Caetano, Fabiana and Sarangi, Sudhir and Keonig, Jennifer and Hao, Haiping and Goldfarb, Joseph and Karpa, Kelly and Vieira, Luciene and Restini, Carolina and Cunningham, Margaret and Aronsson, Patrik and Kelly-Laubscher, Roisin and Hernandez, Mark and Rangachari, PK and Mifsud, Janet and Mraiche, Fatima and Sabra, Ramzi and Piñeros, Octavio and Zhen, Xuechu and Kwanashie, Helen and Exintaris, Betty and Karunaratne, Nilushi and Ishii, Kuniaki (2023) Identifying the core concepts of pharmacology education : a global initiative. British Journal of Pharmacology, 180 (9). pp. 1197-1209. ISSN 1476-5381

2022

Zhang, Xun and Lee, Matthew D. and Buckley, Charlotte and Wilson, Calum and McCarron, John G. (2022) Mitochondria regulate TRPV4 mediated release of ATP. British Journal of Pharmacology, 179 (5). pp. 1017-1032. ISSN 1476-5381

2021

Alexander, Stephen PH and Christopoulos, Arthur and Davenport, Anthony P and Kelly, Eamonn and Mathie, Alistair and Peters, John A and Veale, Emma L and Armstrong, Jane F and Faccenda, Elena and Harding, Simon D and Pawson, Adam J and Southan, Christopher and Davies, Jamie A and Abbracchio, Maria Pia and Alexander, Wayne and Al‐hosaini, Khaled and Bäck, Magnus and Barnes, Nicholas M. and Bathgate, Ross and Beaulieu, Jean‐Martin and Bernstein, Kenneth E. and Bettler, Bernhard and Birdsall, Nigel J.M. and Blaho, Victoria and Boulay, Francois and Bousquet, Corinne and Bräuner‐Osborne, Hans and Burnstock, Geoffrey and Caló, Girolamo and Castaño, Justo P. and Catt, Kevin J. and Ceruti, Stefania and Chazot, Paul and Chiang, Nan and Chini, Bice and Chun, Jerold and Cianciulli, Antonia and Civelli, Olivier and Clapp, Lucie H. and Couture, Réjean and Csaba, Zsolt and Dahlgren, Claes and Dent, Gordon and Singh, Khuraijam Dhanachandra and Douglas, Steven D. and Dournaud, Pascal and Eguchi, Satoru and Escher, Emanuel and Filardo, Edward J. and Fong, Tung and Fumagalli, Marta and Gainetdinov, Raul R and Gasparo, Marc de and Gerard, Craig and Gershengorn, Marvin and Gobeil, Fernand and Goodfriend, Theodore L. and Goudet, Cyril and Gregory, Karen J. and Gundlach, Andrew L. and Hamann, Jörg and Hanson, Julien and Hauger, Richard L. and Hay, Debbie L. and Heinemann, Akos and Hollenberg, Morley D. and Holliday, Nicholas D. and Horiuchi, Mastgugu and Hoyer, Daniel and Hunyady, László and Husain, Ahsan and IJzerman, Adriaan P. and Inagami, Tadashi and Jacobson, Kenneth A. and Jensen, Robert T. and Jockers, Ralf and Jonnalagadda, Deepa and Karnik, Sadashiva and Kaupmann, Klemens and Kemp, Jacqueline and Kennedy, Charles and Kihara, Yasuyuki and Kitazawa, Takio and Kozielewicz, Pawel and Kreienkamp, Hans‐Jürgen and Kukkonen, Jyrki P. and Langenhan, Tobias and Leach, Katie and Lecca, Davide and Lee, John D. and Leeman, Susan E. and Leprince, Jérôme and Li, Xaria X. and Williams, Tom Lloyd and Lolait, Stephen J. and Lupp, Amelie and Macrae, Robyn and Maguire, Janet and Mazella, Jean and McArdle, Craig A. and Melmed, Shlomo and Michel, Martin C. and Miller, Laurence J. and Mitolo, Vincenzo and Mouillac, Bernard and Müller, Christa E. and Murphy, Philip and Nahon, Jean‐Louis and Ngo, Tony and Norel, Xavier and Nyimanu, Duuamene and O’Carroll, Anne‐Marie and Offermanns, Stefan and Panaro, Maria Antonietta and Parmentier, Marc and Pertwee, Roger G. and Pin, Jean‐Philippe and Prossnitz, Eric R. and Quinn, Mark and Ramachandran, Rithwik and Ray, Manisha and Reinscheid, Rainer K. and Rondard, Philippe and Rovati, G. Enrico and Ruzza, Chiara and Sanger, Gareth J. and Schöneberg, Torsten and Schulte, Gunnar and Schulz, Stefan and Segaloff, Deborah L. and Serhan, Charles N. and Stoddart, Leigh A. and Sugimoto, Yukihiko and Summers, Roger and Tan, Valerie P. and Thal, David and Thomas, Walter (Wally) and Timmermans, Pieter B. M. W. M. and Tirupula, Kalyan and Tulipano, Giovanni and Unal, Hamiyet and Unger, Thomas and Valant, Celine and Vanderheyden, Patrick and Vaudry, David and Vaudry, Hubert and Vilardaga, Jean‐Pierre and Walker, Christopher S. and Wang, Ji Ming and Ward, Donald T. and Wester, Hans‐Jürgen and Willars, Gary B and Woodruff, Trent M. and Yao, Chengcan and Ye, Richard D. (2021) The concise guide to pharmacology 2021/22 : G protein‐coupled receptors. British Journal of Pharmacology, 178 (S1). S27-S156. ISSN 1476-5381

Alexander, Stephen PH and Mathie, Alistair and Peters, John A and Veale, Emma L and Striessnig, Jörg and Kelly, Eamonn and Armstrong, Jane F and Faccenda, Elena and Harding, Simon D and Pawson, Adam J and Southan, Christopher and Davies, Jamie A and Aldrich, Richard W. and Attali, Bernard and Baggetta, Austin M and Becirovic, Elvir and Biel, Martin and Bill, Roslyn M. and Catterall, William A. and Conner, Alex C. and Davies, Paul and Delling, Markus and Virgilio, Francesco Di and Falzoni, Simonetta and Fenske, Stefanie and George, Chandy and Goldstein, Steve A. N. and Grissmer, Stephan and Ha, Kotdaji and Hammelmann, Verena and Hanukoglu, Israel and Jarvis, Mike and Jensen, Anders A. and Kaczmarek, Leonard K. and Kellenberger, Stephan and Kennedy, Charles and King, Brian and Kitchen, Philip and Lynch, Joseph W. and Perez‐Reyes, Edward and Plant, Leigh D. and Rash, Lachlan and Ren, Dejian and Salman, Mootaz M. and Sivilotti, Lucia G. and Smart, Trevor G. and Snutch, Terrance P. and Tian, Jinbin and Trimmer, James S. and Van den Eynde, Charlotte and Vriens, Joris and Wei, Aguan D. and Winn, Brenda T. and Wulff, Heike and Xu, Haoxing and Yue, Lixia and Zhang, Xiaoli and Zhu, Michael (2021) The concise guide to pharmacology 2021/22 : ion channels. British Journal of Pharmacology, 178 (S1). S157-S245. ISSN 1476-5381

Zhang, Xun and Alhasani, Reem Hasaballah and Zhou, Xinzhi and Reilly, James and Zeng, Zhihong and Strang, Niall and Shu, Xinhua (2021) Oxysterols and retinal degeneration. British Journal of Pharmacology, 178 (16). pp. 3205-3219. ISSN 1476-5381

Buckley, Charlotte and Zhang, Xun and Wilson, Calum and McCarron, John G. (2021) Carbenoxolone and 18β-glycyrrhetinic acid inhibit inositol 1,4,5-trisphosphate-mediated endothelial cell calcium signalling and depolarise mitochondria. British Journal of Pharmacology, 178 (4). pp. 896-912. ISSN 1476-5381

Illes, Peter and Müller, Christa E. and Jacobson, Kenneth A. and Grutter, Thomas and Nicke, Annette and Fountain, Samuel J. and Kennedy, Charles and Schmalzing, Günther and Jarvis, Michael F. and Stojilkovic, Stanko S. and King, Brian F. and Di Virgilio, Francesco (2021) Update of P2X receptor properties and their pharmacology : IUPHAR review 30. British Journal of Pharmacology, 178 (3). pp. 489-514. ISSN 1476-5381

2020

Buckley, Charlotte and Wilson, Calum and McCarron, John G. (2020) FK506 regulates IP3 evoked Ca2+ release independently of FKBP in endothelial cells. British Journal of Pharmacology, 177 (5). pp. 1131-1149. ISSN 1476-5381

Jacobson, Kenneth A. and Delicado, Esmerilda G. and Gachet, Christian and Kennedy, Charles and von Kügelgen, Ivar and Li, Beibei and Miras-Portugal, M. Teresa and Novak, Ivana and Schöneberg, Torsten and Perez-Sen, Raquel and Thor, Doreen and Wu, Beili and Yang, Zhenlin and Müller, Christa E. (2020) Update of P2Y receptor pharmacology : IUPHAR Review 27. British Journal of Pharmacology, 177 (11). 2413–2433. ISSN 1476-5381

2019

Heathcote, Helen R. and Lee, Matthew D. and Zhang, Xun and Saunter, Christopher D. and Wilson, Calum and McCarron, John G. (2019) Endothelial TRPV4 channels modulate vascular tone by Ca 2+-induced Ca 2+ release at inositol 1,4,5-trisphosphate receptors. British Journal of Pharmacology, 176 (17). pp. 3297-3317. ISSN 1476-5381

Muoboghare, Markie O. and Drummond, Robert M. and Kennedy, Charles (2019) Characterisation of P2Y2 receptors in human vascular endothelial cells using AR-C118925XX, a competitive and selective P2Y2 antagonist. British Journal of Pharmacology, 176 (16). pp. 2894-2904. ISSN 1476-5381

Safar, M.A. and Wood, R. and Cunningham, M.R. and Kennedy, C. (2019) P2Y1 and P2Y12 receptor heterodimerisation : from recombinant systems to native detection. British Journal of Pharmacology, 176 (16). p. 3049. ISSN 1476-5381

2017

Barbour, Mark and McNaughton, Melissa and Boomkamp, Stephanie D. and MacRitchie, Neil and Jiang, Hui-Rong and Pyne, Nigel J and Pyne, Susan (2017) Effect of sphingosine kinase modulators on interleukin-1β release, sphingosine 1-phosphate receptor 1 expression and experimental autoimmune encephalomyelitis : FTY720 analogues and inflammation. British Journal of Pharmacology, 174 (2). pp. 210-222. ISSN 1476-5381

2015

Nisar, S P and Jones, M L and Cunningham, M R and Mumford, A D and Mundell, S J, UK GAPP Study Group (2015) Rare platelet G protein-coupled receptor variants : what can we learn? British Journal of Pharmacology. ISSN 1476-5381

Mooney, L and Skinner, M and Coker, S. J. and Currie, S. (2015) Effect of acute and chronic sunitinib treatment on cardiac function and CaMKII. British Journal of Pharmacology. ISSN 1476-5381

2013

Alexander, Stephen P H and Benson, Helen E and Faccenda, Elena and Pawson, Adam J and Sharman, Joanna L and McGrath, John C and Catterall, William A and Spedding, Michael and Peters, John A and Harmar, Anthony J and Abul-Hasn, N and Anderson, C M and Anderson, C M H and Araiksinen, M S and Arita, M and Arthofer, E and Barker, E L and Barratt, C and Barnes, N M and Bathgate, R and Beart, P M and Belelli, D and Bennett, A J and Birdsall, N J M and Boison, D and Bonner, T I and Brailsford, L and Bröer, S and Brown, P and Calo, G and Carter, W G and Catterall, W A and Chan, S L F and Chao, M V and Chiang, N and Christopoulos, A and Chun, J J and Cidlowski, J and Clapham, D E and Cockcroft, S and Connor, M A and Cox, H M and Cuthbert, A and Dautzenberg, F M and Davenport, A P and Dawson, P A and Jones, R L and Kennedy, C and Pyne, N J and Pyne, S, CGTP Collaborators (2013) The Concise Guide to PHARMACOLOGY 2013/14 : overview. British Journal of Pharmacology, 170 (8). pp. 1449-58. ISSN 1476-5381

Davidson, Jillian and Higgs, Warren and Rotondo, D (2013) Eicosapentaenoic acid suppression of systemic inflammatory responses and inverse up-regulation of 15-deoxy Δ12,14 Prostaglandin J2 production. British Journal of Pharmacology, 169 (5). pp. 1130-1139. ISSN 1476-5381

Tonelli, F. and Alossaimi, M. and Williamson, L. and Tate, R.J. and Watson, D.G. and Chan, E. and Bittman, R. and Pyne, N.J. and Pyne, S. (2013) The sphingosine kinase inhibitor 2-(p-hyroxyanilino)-4-(p-chlorophenyl)thiazole reduces androgen receptor expression via an oxidative stress-dependent mechanism. British Journal of Pharmacology, 168 (6). pp. 1497-1505. ISSN 1476-5381

2012

Lim, Keng Gat and Gray, Alexander I and Pyne, Susan and Pyne, Nigel J (2012) Resveratrol dimers are novel sphingosine kinase 1 inhibitors and affect sphingosine kinase 1 expression and cancer cell growth and survival. British Journal of Pharmacology, 166 (5). pp. 1605-1616. ISSN 1476-5381

Davidson, Jillian and Rotondo, D and Rizzo, Maria and Leaver, Anne (2012) Therapeutic implications of disorders of cell death signalling : membranes, micro-environment, and eicosanoid and docosanoid metabolism. British Journal of Pharmacology, 166 (4). pp. 1193-1210. ISSN 1476-5381

Mitchell, Callum and Syed, Nawazish-I-Husain and Gurney, Alison and Kennedy, Charles (2012) A Ca2+-dependent chloride current and Ca2+ influx via Cav1.2 ion channels play major roles in P2Y receptor-mediated pulmonary vasoconstriction. British Journal of Pharmacology, 166 (4). pp. 1503-1512. ISSN 1476-5381

2011

Gan, J. and Greenwood, S.M. and Cobb, S.R. and Bushell, T.J. (2011) Indirect modulation of neuronal excitability and synaptic transmission in the hippocampus by activation of proteinase-activated receptor-2. British Journal of Pharmacology, 163 (5). pp. 984-994. ISSN 1476-5381

Ledgerwood, Craig and Greenwood, Sam M. and Brett, R.R. and Pratt, J.A. and Bushell, T. (2011) Cannabidiol inhibits synaptic transmission in rat hippocampal cultures and slices via multiple receptor pathways. British Journal of Pharmacology, 162 (1). pp. 286-294. ISSN 1476-5381

Gamble, Carly and McIntosh, Kathryn and Scott, Rebecca and Ho, Ka Ho and Plevin, Robin and Paul, Andrew (2011) Inhibitory kappa B kinases as targets for pharmacological regulation. British Journal of Pharmacology, 165 (4). 802–819. ISSN 1476-5381

Jones, R. L. and Woodward, D. F. and Wang, J. W. and Clark, R. L. (2011) Roles of affinity and lipophilicity in the slow kinetics of prostanoid receptor antagonists on isolated smooth muscle preparations. British Journal of Pharmacology, 162 (4). pp. 863-879. ISSN 1476-5381

2010

MacMillan, D. and McCarron, J.G. (2010) The phospholipase C inhibitor U-73122 inhibits Ca2+ release from the intracellular sarcoplasmic reticulum Ca2+ store by inhibiting Ca2+ pumps in smooth muscle. British Journal of Pharmacology, 160 (6). 1295–1301. ISSN 1476-5381

Mair, K.M. and Kane, K.A. and Pyne, S. and Pyne, N.J. and Kennedy, S. (2010) Interaction between anandamide and sphingosine 1-phosphate in mediating vasorelaxation in rat coronary artery. British Journal of Pharmacology, 161 (1). pp. 176-192. ISSN 1476-5381

Ortolano, F. and Maffia, Pasquale and Dever, G. and Rodolico, G. and Millington, O.R. and De Simoni, M.G. and Brewer, J.M. and Bushell, T. and Garside, P. and Carswell, H.V.O. (2010) Advances in imaging of new targets for pharmacological intervention in stroke : real time tracking of T cells in the ischaemic brain. British Journal of Pharmacology, 159 (4). pp. 808-811. ISSN 1476-5381

Al-Mutairi, Mashael and Al-Harthi, Sameer and Cadalbert, Laurence and Plevin, Robin (2010) Over-expression of MAP kinase phosphatase-2 enhances adhesion molecule expression and protects against apoptosis in human endothelial cells. British Journal of Pharmacology, 161 (4). pp. 782-798. ISSN 1476-5381

McDonald, Robert A. and Pyne, S. and Pyne, N.J. and Wainwright, C.L. and Wadsworth, R.M. (2010) The sphingosine kinase inhibitor N, N-dimethylsphingosine inhibits neointimal hyperplasia. British Journal of Pharmacology, 159 (3). pp. 543-553. ISSN 1476-5381

2009

Goh, F.G. and Ng, P.Y. and Reilly, M. and Kanke, T. and Plevin, R. (2009) Dual effect of the novel peptide antagonist K-14585 on Proteinase-Activated Receptor-2 (PAR2)-mediated signalling. British Journal of Pharmacology, 158 (7). pp. 1695-1704. ISSN 1476-5381

MacMillan, D. and McCarron, J.G. (2009) Regulation by FK506 and rapamycin of Ca2+ release from the sarcoplasmic reticulum in vascular smooth muscle : the role of FK506 binding proteins and mTOR. British Journal of Pharmacology, 158 (4). pp. 1112-1120. ISSN 1476-5381

Jones, R.L. and Giembycz, M.A. and Woodward, D.F. (2009) Prostanoid receptor antagonists: development strategies and therapeutic applications. British Journal of Pharmacology, 158 (1). pp. 104-145. ISSN 1476-5381

Kanke, T. and Kabeya, M. and Kubo, S. and Kondo, S. and Yasuoka, K. and Tagashira, J. and Ishiwata, H. and Saka, M. and Furuyama, T. and Nishiyama, T. and Doi, T. and Hattori, Y. and Kawabata, A. and Cunningham, M.R. and Plevin, R.J. (2009) Novel antagonists for proteinase-activated receptor 2 : Inhibition of cellular and vascular responses in vitro and in vivo. British Journal of Pharmacology, 158 (1). pp. 361-371. ISSN 1476-5381

Walsh, S.K. and Kane, K.A. and Wainwright, C.L. (2009) Mast cell degranulation - a mechanism for the anti-arrhythmic effect of endothelin-1? British Journal of Pharmacology, 157 (5). pp. 716-723. ISSN 1476-5381

Miller, Mark R. and Wadsworth, R.M. (2009) Understanding organic nitrates - a vein hope? British Journal of Pharmacology, 157 (4). pp. 565-567. ISSN 1476-5381

Ong, W.K. and Gribble, F.M. and Reimann, F. and Lynch, M.J. and Houslay, M.D. and Baillie, G.S. and Furman, B.L. and Pyne, N.J. (2009) The role of the PDE4D cAMP phosphodiesterase in the regulation of glucagon-like peptide-1 release. British Journal of Pharmacology, 157 (4). pp. 633-644. ISSN 1476-5381

McCloskey, K.D. and Anderson, U.A. and Davidson, R.A. and Bayguinov, Y.R. and Sanders, K.M. and Ward, S.M. (2009) Comparison of mechanical and electrical activity and interstitial cells of Cajal in urinary bladders from wild-type and W/W-v mice. British Journal of Pharmacology, 156 (2). pp. 273-283. ISSN 1476-5381

2008

Kane, K.A. and Michael, G. and Coker, S.J. (2008) Adrenaline reveals the torsadogenic effect of combined blockade of potassium channels in anaesthetized guinea pigs. British Journal of Pharmacology, 154 (7). pp. 1414-1426. ISSN 1476-5381

Mooney, M.H. and Fogarty, S. and Stevenson, C. and Gallagher, A.M. and Palit, P. and Hawley, S.A. and Hardie, D.G. and Coxon, Geoffrey and Waigh, Roger and Tate, R. and Harvey, Alan and Furman, Brian (2008) Mechanisms underlying the metabolic actions of galegine that contribute to weight loss in mice. British Journal of Pharmacology, 153 (8). pp. 1669-1677. ISSN 1476-5381

Pratt, J.A. and Winchester, C. and Egerton, A. and Cochran, S.M. and Morris, B.J. (2008) Modelling prefrontal cortex deficits in schizophrenia: implications for treatment. British Journal of Pharmacology, 153. S465-S470. ISSN 1476-5381

Farkas, A. and Dempster, J. and Coker, S.J. (2008) Importance of vagally mediated bradycardia for the induction of torsade de pointes in an in vivo model. British Journal of Pharmacology, 154 (5). pp. 958-970. ISSN 1476-5381

2007

Gopal, P. and Tate, R. and Pow, E. and Hill, D. and Connolly, J.G. (2007) The role of the amino acid residue at α1:189 in the binding of neuromuscular blocking agents to mouse and human muscle nicotinic acetylcholine receptors. British Journal of Pharmacology, 150 (7). pp. 920-931. ISSN 1476-5381

Kane, K.A. and Michael, G. and Dempster, J. and Coker, S.J. (2007) Potentiation of E-4031-induced torsade de pointes by HMR1556 or ATX-II is not predicted by action potential short-term variability or triangulation. British Journal of Pharmacology, 152 (8). pp. 1215-1227. ISSN 1476-5381

Ritchie, E. and Saka, M. and MacKenzie, C. and Drummond, R.M. and Wheeler-Jones, C. and Kanke, T. and Plevin, R.J. (2007) Cytokine upregulation of proteinase-activated-receptors 2 and 4 expression mediated by p38 MAP kinase and inhibitory kappa B kinase ß in human endothelial cells. British Journal of Pharmacology, 150. pp. 1044-1054. ISSN 1476-5381

2006

Kane, K.A. and Lim, S.Y. and Tennant, G.M. and Kennedy, S. and Wainwright, C.L. (2006) Activation of mouse protease-activated receptor-2 induces lymphocyte adhesion and generation of reactive oxygen species. British Journal of Pharmacology, 149 (5). pp. 591-599. ISSN 1476-5381

Philp, K.L. and Hussain, M. and Byrne, N.F. and Diver, M.J. and Hart, G. and Coker, Susan J. (2006) Greater antiarrhythmic activity of acute 17ß-estradiol in female than male anaesthetized rats: correlation with Ca2+ channel blockade. British Journal of Pharmacology, 149. pp. 233-242. ISSN 1476-5381

Hatziieremia, S. and Gray, A. and Ferro, V.A. and Paul, A. and Plevin, R.J. (2006) The effects of cardamonin on lipopolysaccharide-induced inflammatory protein production and MAP kinase and nFkappaB signalling pathways in monocytes/macrophages. British Journal of Pharmacology, 149. pp. 188-198. ISSN 1476-5381

Looi, Y.H. and Kane, K.A. and McPhaden, A.R. and Wainwright, C.L. (2006) Adrenomedullin acts via nitric oxide and peroxynitrite to protect against myocardial ischaemia-induced arrhythmias in anaesthetized rats. British Journal of Pharmacology, 148. pp. 599-609. ISSN 1476-5381

2003

Cruickshank, S.F. and Baxter, L.M. and Drummond, R.M. (2003) The cl- channel blocker niflumic acid releases ca2+ from an intracellular store in rat pulmonary artery smooth muscle cells. British Journal of Pharmacology, 140 (8). pp. 1442-1450. ISSN 1476-5381

Pyne, Nigel J and MacLean, Margaret R (2003) An assessment of the role of the inhibitory gamma subunit of the retinal cyclic GMP phosphodiesterase and its effect on the p42/p44 mitogen-activated protein kinase pathway in animal and cellular models of pulmonary hypertension. British Journal of Pharmacology, 138 (7). pp. 1313-9. ISSN 1476-5381

Cameron, P. and Smith, S.J. and Giembycz, M.A. and Rotondo, D. and Plevin, R.J. (2003) Verotoxin activates mitogen-activated protein kinase in human peripheral blood monocytes: role in apoptosis and proinflammatory cytokine release. British Journal of Pharmacology, 140 (7). pp. 1320-1330. ISSN 1476-5381

Shum, W.W.C. and Le, G.Y. and Jones, R.L. and Gurney, A.M. and Sasaki, Y. (2003) Involvement of rho-kinase in contraction of guinea-pig aorta induced by prostanoid eP3 receptor agonists. British Journal of Pharmacology, 139 (8). pp. 1449-1461. ISSN 1476-5381

2002

O'Neill, G.T. and Rowan, E.G. and Gurney, A.M. (2002) Muscarinic receptors and calcium signalling in rabbit isolated pulmonary artery smooth muscle cells. British Journal of Pharmacology, 137 (Suppl.). 24P-24P. ISSN 1476-5381

McCartney, C.E. and Rowan, E.G. and Rowe, I.C.M. (2002) The effects of hypoxia and anoxia on the activity of neuronal large conductance calcium-activated potassium (bkca) channels. British Journal of Pharmacology, 137 (Suppl.). 41P-41P. ISSN 1476-5381

Milliken, P.H. and Wadsworth, R.M. (2002) Superoxide and superoxide dismutase in pulmonary hypoxic vasoconstriction. British Journal of Pharmacology, 137 (Suppl ). 50P-50P. ISSN 1476-5381

Murray, Fiona and MacLean, Margaret R and Pyne, Nigel J (2002) Increased expression of the cGMP-inhibited cAMP-specific (PDE3) and cGMP binding cGMP-specific (PDE5) phosphodiesterases in models of pulmonary hypertension. British Journal of Pharmacology, 137 (8). pp. 1187-1194. ISSN 1476-5381

Dempster, J and Wokosin, D L and McCloskey, K D and Girkin, J M and Gurney, A M (2002) WinFluor : an integrated system for the simultaneous recording of cell fluorescence images and electrophysiological signals on a single computer system. British Journal of Pharmacology, 137 (procee). 146P-146P. ISSN 1476-5381

Looi, Y.H. and Wainwright, C.L. and Kane, K.A. (2002) Adrenomedullin protects against ischaemia-induced arrhythmias and injury in anaesthetised rats. British Journal of Pharmacology, 135 (Procee). ISSN 1476-5381

Assis, T.S. and Rowan, E.G. and Kennedy, C. (2002) The sensitivity of sensory neurones to P2 receptor agonists differs in intact and dissociated rat dorsal root ganglia. British Journal of Pharmacology, 135. ISSN 1476-5381 (Unpublished)

Batey, Andrew.J. and Coker, Susan J. (2002) Proarrhythmic potential of halofantrine, terfenadine and clofilium in an in vivo model of torsade de pointes. British Journal of Pharmacology, 135 (4). pp. 1003-1012. ISSN 1476-5381

Chootip, K. and Ness, K.F. and Wang, Y. and Gurney, A.M. and Kennedy, C. (2002) Regional variation in p2 receptor expression in the rat pulmonary arterial circulation. British Journal of Pharmacology, 137 (5). pp. 637-646. ISSN 1476-5381

2001

Jarajapu, Y.P. and Coats, Paul and McGrath, John C. and Hillier, Chris and MacDonald, Allan (2001) Functional chracterization of alpha(1)-adrenoceptor subtypes in human skeletal muscle resistance arteries. British Journal of Pharmacology, 133 (5). pp. 679-686. ISSN 1476-5381

Qi, Ai-Dong and Kennedy, C. and Harden, T. Kendall and Nicholas, Robert A. (2001) Differential coupling of the human P2Y11 receptor to phospholipase C and adenylyl cyclase. British Journal of Pharmacology, 132 (1). pp. 318-326. ISSN 1476-5381

Alderton, F. and Sambi, B.S. and Tate, R. and Pyne, N.J. and Pyne, S. (2001) Assessment of agonism at g-protein coupled receptors by phosphatidic acid and lysophosphatidic acid in human embryonic kidney 293 cells. British Journal of Pharmacology, 134 (1). pp. 6-9. ISSN 1476-5381

Jones, R.L. and Chan, K.M. (2001) Distinction between relaxations induced via prostanoid EP4 and IP1 receptors in pig and rabbit blood vessels. British Journal of Pharmacology, 134. pp. 313-324. ISSN 1476-5381

Torrie, L.J. and MacKenzie, C. and Paul, A. and Plevin, R.J. (2001) Hydrogen peroxide-mediated inhibition of lipopolysaccharide-stimulated inhibitory kappa b kinase activity in rat aortic smooth muscle cells. British Journal of Pharmacology, 134 (2). pp. 393-401. ISSN 1476-5381

2000

Ahmad, M and Abdel-Wahab, Y H and Tate, R and Flatt, P R and Pyne, N J and Furman, B L (2000) Effect of type-selective inhibitors on cyclic nucleotide phosphodiesterase activity and insulin secretion in the clonal insulin secreting cell line BRIN-BD11. British Journal of Pharmacology, 129 (6). pp. 1228-1234. ISSN 1476-5381

1998

Mair, I D and Lambert, J J and Yang, J and Dempster, J and Peters, J A (1998) Pharmacological characterization of a rat 5-hydroxytryptamine type3 receptor subunit (r5-HT3A(b)) expressed in Xenopus laevis oocytes. British Journal of Pharmacology, 124 (8). pp. 1667-74. ISSN 1476-5381

1997

Tian, L and Prior, C and Dempster, J and Marshall, I G (1997) Hexamethonium- and methyllycaconitine-induced changes in acetylcholine release from rat motor nerve terminals. British Journal of Pharmacology, 122 (6). pp. 1025-1034. ISSN 1476-5381

1996

Rae, M.G. and Rowan, E.G. and Kennedy, C. (1996) Characterisation of p-2x-purinoceptors in neurones of the neonatal rat dorsal root ganglia. British Journal of Pharmacology, 119. P369-P369. ISSN 1476-5381

Tolan, D and Conway, A M and Steele, L and Pyne, S and Pyne, N J (1996) The identification of DL-threo dihydrosphingosine and sphingosine as novel inhibitors of extracellular signal-regulated kinase signalling in airway smooth muscle. British Journal of Pharmacology, 119 (2). pp. 185-186. ISSN 1476-5381

Robertson, S.J. and Rae, M.G. and Rowan, E.G. and Kennedy, C. (1996) Characterization of a P-2x-purinoceptor in cultured neurones of the rat dorsal root ganglia. British Journal of Pharmacology, 118 (4). pp. 951-956. ISSN 1476-5381

1995

Fatehi, M. and Rowan, E.G. and Harvey, A.L. (1995) Temperature-dependent effects of adenosine on presynaptic calcium currents and acetylcholine-release from mouse motor-nerve terminals. British Journal of Pharmacology, 116 (Supple). P365-P365. ISSN 1476-5381

Fatehi, M. and Rowan, E.G. and Harvey, A.L. and Moya, E. and Blagbrough, I.S. (1995) The effects of polyamine ftx-3.3 and polyamine amide sftx-3.3 on acetyccholine release. British Journal of Pharmacology, 116 (Supple). P367-P367. ISSN 1476-5381

Dempster, John and Prior, Christopher (1995) The use of computer simulations to accompany the laboratory teaching of pharmacological principles. British Journal of Pharmacology, 116 (Suppl). P460-P460. ISSN 1476-5381

Robertson, S.J. and Rowan, E.R. and Kennedy, C. (1995) Characterization of the electrophysiological actions of P-2-purinoceptor agonists in cultured neurons in the rat. British Journal of Pharmacology, 116 (Supple). P54-P54. ISSN 1476-5381

Vatanpour, H and Harvey, A L (1995) Modulation of acetylcholine release at mouse neuromuscular junctions by interaction of three homologous scorpion toxins with K+ channels. British Journal of Pharmacology, 114 (7). pp. 1502-1506. ISSN 1476-5381

Shafiee-Nick, R and Pyne, N J and Furman, B L (1995) Effects of type-selective phosphodiesterase inhibitors on glucose-induced insulin secretion and islet phosphodiesterase activity. British Journal of Pharmacology, 115 (8). pp. 1486-1492. ISSN 1476-5381

1994

Burns, F and Stevens, P A and Pyne, N J (1994) The identification of apparently novel cyclic AMP and cyclic GMP phosphodiesterase activities in guinea-pig tracheal smooth muscle. British Journal of Pharmacology, 113 (1). pp. 3-4. ISSN 1476-5381

Fatehi, M. and Rowan, E.G. and Harvey, A.L. (1994) Characterization of the effects of depolarizing phospholipases A-2, myotoxin a and ouabain on the perineural waveforms recorded from mouse motor nerve endings. British Journal of Pharmacology, 112 (Supple). U76-U76. ISSN 1476-5381

1993

Hollecker, M and Marshall, D L and Harvey, A L (1993) Structural features important for the biological activity of the potassium channel blocking dendrotoxins. British Journal of Pharmacology, 110 (2). pp. 790-794. ISSN 1476-5381

Pyne, S and Pyne, N J (1993) Differential effects of B(2) receptor antagonists upon bradykinin-stimulated phospholipase C and phospholipase D in guinea-pig cultured tracheal smooth muscle. British Journal of Pharmacology, 110 (1). pp. 477-481. ISSN 1476-5381

1992

Braga, M.F.M. and Rowan, E.G. (1992) Reversal by cysteine of the cadmium-induced block of skeletal neuromuscular transmission in vitro. British Journal of Pharmacology, 107 (1). pp. 95-100. ISSN 1476-5381

Braga, M.F.M. and Anderson, A.J. and Harvey, A.L. and Rowan, E.G. (1992) Apparent block of K+ currents in mouse motor nerve terminals by tetrodotoxin, mu-conotoxin and reduced external sodium. British Journal of Pharmacology, 106 (1). pp. 91-94. ISSN 1476-5381

Connolly, John and Boulter, Jim and Heinemann, Stephen F. (1992) Alpha 4-2 beta 2 and other nicotinic acetylcholine receptor subtypes as targets of psychoactive and addictive drugs. British Journal of Pharmacology, 105 (3). pp. 657-666. ISSN 1476-5381

Pyne, N J and Grady, M W and Shehnaz, D and Stevens, P A and Pyne, S and Rodger, I W (1992) Muscarinic blockade of beta-adrenoceptor-stimulated adenylyl cyclase: the role of stimulatory and inhibitory guanine-nucleotide binding regulatory proteins (Gs and Gi). British Journal of Pharmacology, 107 (3). pp. 881-7. ISSN 1476-5381

1991

Braga, M.F.M. and Harvey, A.L. and Rowan, E.G. (1991) Effects of tacrine, velnacrine (HP029), suronacrine (HP128),and 3,4-diaminopyridine on skeletal neuromusculartransmission in vitro. British Journal of Pharmacology, 102 (4). pp. 909-915. ISSN 1476-5381

1990

Rowan, E.G. and Pemberton, K.E. and Harvey, Alan L. (1990) On the blockade of acetylcholine release at mouse motor nerve terminals by beta-bungarotoxin and crotoxin. British Journal of Pharmacology, 100 (2). pp. 301-304. ISSN 1476-5381

1989

Lambert, J J and Peters, J A and Hales, T G and Dempster, J (1989) The properties of 5-HT3 receptors in clonal cell lines studied by patch-clamp techniques. British Journal of Pharmacology, 97 (1). pp. 27-40. ISSN 1476-5381

1988

Anderson, A.J. and Harvey, Alan L. and Rowan, E.G. and Strong, P.N. (1988) Effects of charybdotoxin, a blocker of Ca2+-activated K+ channels, on motor nerve terminals. British Journal of Pharmacology, 95 (4). pp. 1329-1335. ISSN 1476-5381

Rowan, E.G. and Harvey, Alan L. (1988) Potassium channel blocking actions of beta-bungarotoxin and related toxins on mouse and frog motor nerve terminals. British Journal of Pharmacology, 94 (3). pp. 839-847. ISSN 1476-5381

Estrella, D and Green, K L and Prior, C and Dempster, J and Halliwell, R F and Jacobs, R S and Parsons, S M and Parsons, R L and Marshall, I G (1988) A further study of the neuromuscular effects of vesamicol (AH5183) and of its enantiomer specificity. British Journal of Pharmacology, 93 (4). pp. 759-768. ISSN 1476-5381

Anderson, A J and Harvey, A L (1988) Effects of the potassium channel blocking dendrotoxins on acetylcholine release and motor nerve terminal activity. British Journal of Pharmacology, 93 (1). pp. 215-221. ISSN 1476-5381

1987

Dempster, J and Jones, S V and Marshall, I G (1987) A kinetic analysis of the endplate ion channel blocking action of disopyramide and its optical isomers. British Journal of Pharmacology, 90 (2). pp. 299-307. ISSN 1476-5381

1984

Harvey, A L and Hider, R C and Hodges, S J and Joubert, F J (1984) Structure-activity studies of homologues of short chain neurotoxins from Elapid snake venoms. British Journal of Pharmacology, 82 (3). pp. 709-716. ISSN 1476-5381

1982

Harvey, A L and Karlsson, E (1982) Protease inhibitor homologues from mamba venoms : facilitation of acetylcholine release and interactions with prejunctional blocking toxins. British Journal of Pharmacology, 77 (1). pp. 153-161. ISSN 1476-5381