Cytokine upregulation of proteinase-activated-receptors 2 and 4 expression mediated by p38 MAP kinase and inhibitory kappa B kinase ß in human endothelial cells

Ritchie, E. and Saka, M. and MacKenzie, C. and Drummond, R.M. and Wheeler-Jones, C. and Kanke, T. and Plevin, R.J. (2007) Cytokine upregulation of proteinase-activated-receptors 2 and 4 expression mediated by p38 MAP kinase and inhibitory kappa B kinase ß in human endothelial cells. British Journal of Pharmacology, 150. pp. 1044-1054. ISSN 1476-5381 (http://dx.doi.org/10.1038/sj.bjp.0707150)

Abstract

Up-regulation of proteinase-activated receptor-2 (PAR2) is a factor in a number of disease states and we have therefore examined the signalling pathways involved in the expression of the receptor.

ORCID iDs

Drummond, R.M. ORCID: https://orcid.org/0000-0003-0003-609X

Plevin, R.J. ORCID: https://orcid.org/0000-0002-7849-1220

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  Item type:	Article
  ID code:	7623
  Dates:	Date Event 2007 Published
  Keywords:	adenovirus, 2-furoyl(2f)-LIGKV-OH, human umbilical vein, endothelial cells, inhibitory kappa, B kinase, nuclear factor, kappa B, proteinase-activated receptor, Pharmacy and materia medica, Pharmacology
  Subjects:	Medicine > Pharmacy and materia medica
  Department:	Faculty of Science > Strathclyde Institute of Pharmacy and Biomedical Sciences
  Depositing user:	Strathprints Administrator
  Date deposited:	03 Mar 2009 11:43
  Last modified:	26 Jan 2023 03:03
  URI:	https://strathprints.strath.ac.uk/id/eprint/7623