Cytokine upregulation of proteinase-activated-receptors 2 and 4 expression mediated by p38 MAP kinase and inhibitory kappa B kinase ß in human endothelial cells

Ritchie, E. and Saka, M. and MacKenzie, C. and Drummond, R.M. and Wheeler-Jones, C. and Kanke, T. and Plevin, R.J. (2007) Cytokine upregulation of proteinase-activated-receptors 2 and 4 expression mediated by p38 MAP kinase and inhibitory kappa B kinase ß in human endothelial cells. British Journal of Pharmacology, 150. pp. 1044-1054. ISSN 1476-5381

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Abstract

Up-regulation of proteinase-activated receptor-2 (PAR2) is a factor in a number of disease states and we have therefore examined the signalling pathways involved in the expression of the receptor.

ORCID iDs

Ritchie, E., Saka, M., MacKenzie, C., Drummond, R.M. ORCID logoORCID: https://orcid.org/0000-0003-0003-609X, Wheeler-Jones, C., Kanke, T. and Plevin, R.J. ORCID logoORCID: https://orcid.org/0000-0002-7849-1220;