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Open Access research that solves space system engineering problems...

Strathprints makes available scholarly Open Access content by scholars in the Department of Mechanical & Aerospace Engineering (MAE), based within the Faculty of Engineering.

Research at MAE includes research into space systems engineering and spaceflight mechanics. This spans a wide variety of topics such as nano-satellites, self-assembling spacecraft, orbital dynamics, trajectory design and optimization, autonomous navigation and planning, all under the auspices of the Aerospace Centre of Excellence - and with almost all research outputs openly available through Strathprints.

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Number of items: 63.

2019

Zhang, Xun and Lee, Matthew D. and Wilson, Calum and McCarron, John G. (2019) Hydrogen peroxide depolarizes mitochondria and inhibits IP3-evoked Ca2+ release in the endothelium of intact arteries. Cell Calcium, 84. 102108. ISSN 0143-4160

Lawton, Penelope F. and Buckley, Charlotte and Saunter, Christopher D. and Wilson, Calum and Corbett, Alexander D. and Slater, Patrick S. and McCarron, John G. and Girkin, John M. (2019) Multi-plane remote refocussing epifluorescence microscopy to image dynamic Ca2+ events. Biomedical Optics Express, 10 (11). pp. 5611-5624. ISSN 2156-7085

Buckley, Charlotte and Wilson, Calum and McCarron, John G. (2019) FK506 regulates IP3 evoked Ca2+ release independently of FKBP in endothelial cells. British Journal of Pharmacology. ISSN 1476-5381 (In Press)

Heathcote, Helen R. and Lee, Matthew D. and Zhang, Xun and Saunter, Christopher D. and Wilson, Calum and McCarron, John G. (2019) Endothelial TRPV4 channels modulate vascular tone by Ca 2+-induced Ca 2+ release at inositol 1,4,5-trisphosphate receptors. British Journal of Pharmacology, 176 (17). pp. 3297-3317. ISSN 1476-5381

Wilson, Calum and Zhang, Xun and Buckley, Charlotte and Heathcote, Helen R. and Lee, Matthew D. and McCarron, John G. (2019) Increased vascular contractility in hypertension results from impaired endothelial calcium signaling. Hypertension, 74 (5). pp. 1200-1214. ISSN 1524-4563

McCarron, John G and Wilson, Calum and Heathcote, Helen R and Zhang, Xun and Buckley, Charlotte and Lee, Matthew D (2019) Heterogeneity and emergent behaviour in the vascular endothelium. Current Opinion in Pharmacology, 45. pp. 23-32. ISSN 1471-4892

Lawton, Penelope F. and Lee, Matthew D. and Saunter, Christopher D. and Girkin, John M. and McCarron, John G. and Wilson, Calum (2019) VasoTracker, a low-cost and open source pressure myograph system for vascular physiology. Frontiers in Physiology, 10 (FEB). 99. ISSN 1664-042X

Wilson, Calum and Lee, Matthew D. and Heathcote, Helen R. and Zhang, Xun and Buckley, Charlotte and Girkin, John M. and Saunter, Christopher D. and McCarron, John G. (2019) Mitochondrial ATP production provides long-range control of endothelial inositol trisphosphate–evoked calcium signaling : mitochondrial control of endothelial Ca2+ signaling. Journal of Biological Chemistry, 294 (3). pp. 737-758. ISSN 1083-351X

2018

Lee, Matthew D. and Wilson, Calum and Saunter, Christopher D. and Kennedy, Charles and Girkin, John M. and McCarron, John G. (2018) Spatially-structured cell populations process multiple sensory signals in parallel in intact vascular endothelium : stimulus-specific sensory cells in the intact vascular endothelium. Science Signaling, 11 (561). eaar4411. ISSN 1945-0877

McCarron, John G. and Saunter, Christopher and Wilson, Calum and Girkin, John M. and Chalmers, Susan (2018) Mitochondria structure and position in the local control of calcium signals in smooth muscle cells. In: Signal Transduction and Smooth Muscle. CRC Press, Boca Raton, Florida, pp. 173-190. ISBN 9781498774222

Casciano, Jessica C. and Cohen-Nowak, Adam and Vande Voorde, Johan and Zhang, Qifeng and Chalmers, Susan and Sandison, Mairi and Hedley, Ann and McBryan, Tony and Beer, Thomas and Tang, Hsin-Yao and Speicher, David W. and Adams, Peter and Liu, Xiufeng and Schlegel, Richard and McCarron, John and Wakelam, Michael J. and Gottlieb, Eyal and Schug, Zachary T. (2018) Abstract 1441 : MYC expression promotes lipid metabolism and metabolic plasticity in human mammary epithelial cell. Cancer Research, 78 (13 Sup). ISSN 0008-5472

Patnaik, Sarita Rani and Zhang, Xun and Biswas, Lincoln and Akhtar, Saeed and Zhou, Xinzhi and Kusuluri, Deva Krupakar and Reilly, James and May-Simera, Helen and Chalmers, Susan and McCarron, John G. and Shu, Xinhua (2018) RPGR protein complex regulates proteasome activity and mediates store-operated calcium entry. Oncotarget, 9 (33). pp. 23183-23197. ISSN 1949-2553

Ratnayake, Manuela and Wilson, Calum and Lee, Matthew D. and Girkin, John M. and Saunter, Christopher M. and McCarron, John (2018) Complex Interactions of excitatory and inhibitory stimuli in the vascular endothelium. FASEB Journal, 32 (1 Supp). 843.5. ISSN 0892-6638

2017

McCarron, John G. and Lee, Matthew D. and Wilson, Calum (2017) The endothelium solves problems that endothelial cells do not know exist. Trends in Pharmacological Sciences, 38 (4). pp. 322-338. ISSN 0165-6147

Wilson, Calum and Saunter, Christopher D. and Girkin, John M. and McCarron, John G. (2017) Advancing age decreases pressure-sensitive modulation of calcium signaling in the endothelium of intact and pressurized arteries. Journal of Vascular Research, 53 (5-6). 358–369. ISSN 1018-1172

2016

Wilson, Calum and Lee, Matthew D. and McCarron, John G. (2016) Acetylcholine released by endothelial cells facilitates flow-mediated dilatation. Journal of Physiology, 594 (24). pp. 7267-7307. ISSN 0022-3751

Sandison, Mairi E. and Dempster, John and McCarron, John G. (2016) The transition of smooth muscle cells from a contractile to a migratory, phagocytic phenotype : direct demonstration of phenotypic modulation. Journal of Physiology, 594 (21). pp. 6189-6209. ISSN 1469-7793

Chalmers, Susan and Saunter, Christopher and Girkin, John M. and McCarron, John G. (2016) Age decreases mitochondrial motility and increases mitochondrial size in vascular smooth muscle : Smooth muscle mitochondrial shape and motility changes with age. Journal of Physiology, 594 (15). 4283–4295. ISSN 0022-3751

McCarron, John G. and Chalmers, Susan and Wilson, Calum and Sandison, Mairi E. (2016) Calcium mobilization via intracellular ion channels, store organization and mitochondria in smooth muscle. In: Vascular Ion Channels in Physiology and Disease. Springer, Berlin, pp. 233-254. ISBN 978-3-319-29635-7

Wilson, Calum and Saunter, Christopher D. and Girkin, John M. and McCarron, John G. (2016) Clusters of specialized detector cells provide sensitive and high fidelity receptor signaling in intact endothelium. FASEB Journal, 30 (5). pp. 2000-2013. ISSN 0892-6638

2015

Caldwell, Stuart T. and Cairns, Andrew G. and Olson, Marnie and Chalmers, Susan and Sandison, Mairi and Mullen, William and McCarron, John G. and Hartley, Richard C. (2015) Synthesis of an azido-tagged low affinity ratiometric calcium sensor. Tetrahedron, 71 (51). 9571–9578. ISSN 0040-4020

Wilson, Calum and Saunter, Christopher D. and Girkin, John M. and McCarron, John G. (2015) Pressure-dependent regulation of Ca2+ signaling in the vascular endothelium. Journal of Physiology, 593 (24). pp. 5231-5253. ISSN 1469-7793

Chalmers, Susan and Saunter, Christopher D. and Girkin, John M. and McCarron, John G. (2015) Flicker-assisted localization microscopy reveals altered mitochondrial architecture in hypertension. Scientific Reports, 5. ISSN 2045-2322

Sandison, Mairi and McCarron, John (2015) Heterogeneity in the proliferative capacity of smooth muscle cells (SMCs). FASEB Journal, 29 (Suppl.). 418.8. ISSN 0892-6638

2014

Sandison, Mairi and Chalmers, Susan and Dempster, John and McCarron, John (2014) Direct visualisation of smooth muscle cell phenotypic plasticity and migration by long-term imaging. FASEB Journal, 28 (Suppl ). 867.12. ISSN 0892-6638

2013

McCarron, J.G. and Wilson, C. and Sandison, M.E. and Olson, M.L. and Girkin, J.M. and Saunter, C. and Chalmers, S. (2013) From structure to function : mitochondrial morphology, motion and shaping in vascular smooth muscle. Journal of Vascular Research, 50 (5). pp. 357-371. ISSN 1018-1172

Mccarron, John G. and Olson, Marnie L. and Wilson, Calum and Sandison, Mairi E. and Chalmers, Susan (2013) Examining the role of mitochondria in Ca2+ Signaling in native vascular smooth muscle. Microcirculation, 20 (4). pp. 317-329. ISSN 1549-8719

McCarron, John G. and Olson, Marnie L. and Chalmers, Susan and Girkin, John M. (2013) Single cell and subcellular measurements of intracellular Ca2+ concentration. In: Calcium Signaling Protocols. Methods in Molecular Biology, 937 . Humana Press, pp. 239-251. ISBN 978-1-62703-086-1

2012

Chalmers, Susan and Saunter, Chris and Wilson, Calum and Coats, Paul and Girkin, John and McCarron, John (2012) Mitochondrial motility and vascular smooth muscle proliferation. Arteriosclerosis Thrombosis, and Vascular Biology, 32 (12). pp. 3000-3011. ISSN 1524-4636

Chalmers, Susan and Saunter, Christopher and Wilson, Calum and Coats, Paul and Girkin, John M and McCarron, John G (2012) Mitochondrial motility and vascular smooth muscle proliferation. Arteriosclerosis Thrombosis, and Vascular Biology, 32 (12). pp. 3000-3011. ISSN 1079-5642

Olson, Marnie L. and Sandison, Mairi E. and Chalmers, Susan and McCarron, John G. (2012) Microdomains of muscarinic acetylcholine and InsP3 receptors create InsP3 junctions and sites of Ca2+ wave initiation in smooth muscle. Journal of Cell Science, 125. pp. 5315-5328. ISSN 0021-9533

MacMillan, Debbi and Kennedy, Charles and McCarron, John (2012) ATP inhibits Ins(1,4,5)P3-evoked Ca2+ release in smooth muscle via P2Y1 receptors. Journal of Cell Science, 125 (21). pp. 5151-5158. ISSN 0021-9533

McCarron, John and Chalmers, Susan and Olson, Marnie and Girkin, John (2012) Subplasma membrane Ca2+ signals. IUBMB Life, 64 (7). pp. 573-585.

Olson, Marnie L and Chalmers, Susan and McCarron, John G (2012) Mitochondrial organization and Ca2+ uptake. Biochemical Society Transactions, 40 (1). pp. 158-167.

McCarron, John and Olson, Marnie and Chalmers, Susan (2012) Mitochondrial regulation of cytosolic Ca2+ signals in smooth muscle. Pflügers Archiv European Journal of Physiology, 464 (specia). pp. 51-62.

Chalmers, Susan and Caldwell, S.T. and Quin, C and Prime, T.A. and James, A.M. and Cairns, Alan and Murphy, M.P. and McCarron, John and Hartley, R.C. (2012) Selective uncoupling of individual mitochondria within a cell using a mitochondria-targeted photoactivated protonophore. Journal of the American Chemical Society, 134 (2). pp. 758-761.

2011

Chalmers, S. and Coats, P. and McCarron, J. G. (2011) Mitochondrial motility and vascular smooth muscle proliferation. Heart, 97 (24). ISSN 1468-201X

McCarron, J. and Chalmers, S. and Olson, M. (2011) Modulation of calcium signalling pathways. Journal of Vascular Research, 48 (Suppl.). p. 42. IS24. ISSN 1018-1172

2010

McCarron, J.G. and Chalmers, S. and MacMillan, D. and Olson, M.L. (2010) Agonist-evoked Ca2+ wave progression requires Ca2+ and IP3. Journal of Cellular Physiology, 224 (2). pp. 334-344. ISSN 0021-9541

MacMillan, D. and McCarron, J.G. (2010) The phospholipase C inhibitor U-73122 inhibits Ca2+ release from the intracellular sarcoplasmic reticulum Ca2+ store by inhibiting Ca2+ pumps in smooth muscle. British Journal of Pharmacology, 160 (6). 1295–1301. ISSN 1476-5381

Olson, M. and Chalmers, S. and McCarron, John G. (2010) Mitochondrial Ca2+ uptake increases Ca2+ release from Inositol 1,4,5-trisphosphate receptor clusters in smooth muscle cells. Journal of Biological Chemistry, 285 (3). pp. 2040-2050. ISSN 1083-351X

2009

Rainbow, R. and MacMillan, D. and McCarron, J.G. (2009) The sarcoplasmic reticulum Ca2+ store arrangement in vascular smooth muscle. Cell Calcium, 45 (5-6). pp. 313-322. ISSN 0143-4160

MacMillan, D. and McCarron, J.G. (2009) Regulation by FK506 and rapamycin of Ca2+ release from the sarcoplasmic reticulum in vascular smooth muscle : the role of FK506 binding proteins and mTOR. British Journal of Pharmacology, 158 (4). pp. 1112-1120. ISSN 1476-5381

McCarron, J.G. and Olson, M. and Currie, S. and Wright, A. and Anderson, K.I. and Girkin, J.M. (2009) Elevations of intracellular calcium reflect normal voltage-dependent behavior, and not constitutive activity, of voltage-dependent calcium channels in gastrointestinal and vascular smooth muscle. Journal of General Physiology, 133 (4). pp. 439-457. ISSN 0022-1295

Avionitis, N. and Chalmers, S. and McDougall, C. and Stanton-Humphreys, M.N. and Brown, C.T.A. and McCarron, J.G. and Conway, S.J. (2009) Caged AG10: new tools for spatially predefined mitochondrial uncoupling. Molecular BioSystems, 5. pp. 450-457. ISSN 1742-206X

Chalmers, S. and McCarron, J.G. (2009) Inhibition of mitochondrial calcium uptake rather than efflux impedes calcium release by inositol-1,4,5-trisphosphate-sensitive receptors. Cell Calcium, 46 (2). pp. 107-113. ISSN 0143-4160

2008

Currie, S. and Rainbow, R. and Ewart, M-A. and Kitson, S. and Pliego, E.H. and Kane, K.A. and McCarron, J.G. (2008) IP3R-mediated Ca2+ release is modulated by anandamide in isolated cardiac nuclei. Journal of Molecular and Cellular Cardiology, 45 (6). pp. 804-811. ISSN 0022-2828

McCarron, J.G. and Olson, Marnie (2008) A single luminally continuous sarcoplasmic reticulum with apparently separate Ca2+ stores in smooth muscle. Journal of Biological Chemistry, 283 (11). pp. 7206-7218. ISSN 1083-351X

Chalmers, S. and McCarron, J.G. (2008) The mitochondrial membrane potential and Ca2+ oscillations in smooth muscle. Journal of Cell Science, 121 (1). pp. 75-85. ISSN 0021-9533

MacMillan, D. and Currie, S. and McCarron, J.G. (2008) FK506-binding protein (FKBP12) regulates ryanodine receptor-evoked Ca2+ release in colonic but not aortic smooth muscle. Cell Calcium, 43 (6). pp. 539-549. ISSN 0143-4160

McCarron, J.G. and Chalmers, S. and Muir, T.C. (2008) "Quantal" Ca2+ release at the cytoplasmic aspect of the Ins(1,4,5)P3R channel in smooth muscle. Journal of Cell Science, 121 (1). pp. 86-98. ISSN 0021-9533

2007

Chalmers, S. and Olson, M. and MacMillan, D. and Rainbow, R. and McCarron, J.G. (2007) Ion channels in smooth muscle: regulation by the sarcoplasmic reticulum and mitochondria. Cell Calcium, 42 (4-5). pp. 447-466. ISSN 0143-4160

McCarron, J.G. and Olson, M. and Rainbow, R. and MacMillan, D. and Chalmers, S. (2007) Ins(1,4,5)P3 receptor regulation during ‘quantal’ Ca2+ release in smooth muscle. Trends in Pharmacological Sciences, 28 (6). pp. 271-279. ISSN 0165-6147

2006

McCarron, John G. and Chalmers, Susan and Bradley, Karen N. and MacMillan, Debbi and Muir, Thomas C. (2006) Ca2+ microdomains in smooth muscle. Cell Calcium, 40 (5-6). pp. 461-493. ISSN 0143-4160

2005

MacMillan, D. and Currie, S. and Bradley, K.N. and Muir, T.C. and McCarron, J.G. (2005) In smooth muscle, FK506-binding protein modulates IP3 receptor-evoked Ca2+ release by mTOR and calcineurin. Journal of Cell Science, 118 (23). pp. 5443-5451. ISSN 0021-9533

MacMillan, D. and Chalmers, S. and Muir, T.C. and McCarron, J.G. (2005) IP3-mediated Ca2+ increases do not involve the ryanodine receptor, but ryanodine receptor antagonists reduce IP3-mediated Ca2+ increases in guinea-pig colonic smooth muscle cells. Journal of Physiology, 569 (2). pp. 533-544. ISSN 0022-3751

2004

Mccarron, John and Bradley, Karen and Macmillan, Debbi and Chalmers, Susan and Muir, Thomas C. (2004) The sarcoplasmic reticulum, Ca2+ trapping, and wave mechanisms in smooth muscle. News in Physiological Sciences, 19. pp. 138-147. ISSN 0886-1714

McCarron, J.G. and MacMillan, D. and Bradley, K.N. and Chalmers, S. and Muir, T.C. (2004) Origin and mechanisms of Ca2+ waves in smooth muscle as revealed by localized photolysis of caged inositol 1,4,5-trisphosphate. Journal of Biological Chemistry, 279. pp. 8417-8427. ISSN 1083-351X

2003

Mccarron, John and Bradley, Karen and MacMillan, Debbi and Muir, Thomas C. (2003) Sarcolemma agonist-induced interactions between InsP3 and ryanodine receptors in Ca2+ oscillations and waves in smooth muscle. Biochemical Society Transactions, 31 (5). pp. 920-924. ISSN 0300-5127

Bradley, K.N. and Currie, S. and MacMillan, D. and Muir, T.C. and McCarron, J.G. (2003) Cyclic ADP-ribose increases Ca2+ removal in smooth muscle. Journal of Cell Science, 116. pp. 4291-306. ISSN 0021-9533

2002

McCarron, J.G. and Craig, J.W. and Bradley, K.N. and Muir, T.C. (2002) Agonist-induced phasic and tonic responses in smooth muscle are mediated by InsP3. Journal of Cell Science, 115. pp. 2207-2218. ISSN 0021-9533

Bradley, K.N. and Flynn, E.R.M. and Muir, T.C. and McCarron, J.G. (2002) Ca2+ regulation in guinea pig colonic smooth muscle: the role of the na+-Ca2+ exchanger and the sarcoplasmic reticulum. Journal of Physiology, 538. pp. 465-482. ISSN 0022-3751

2001

Flynn, Elaine R.M. and Bradley, Karen N. and Muir, Thomas C. and McCarron, John G. (2001) Functionally-separate intracellular ca2+ stores in smooth muscle. Journal of Biological Chemistry, 276. pp. 36411-18. ISSN 1083-351X

This list was generated on Sat Dec 14 05:49:33 2019 GMT.