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2016

Scales, Hannah E. and Ierna, Michelle and Smith, Karen M. and Ross, Kirsty and Meiklejohn, Gordon R. and Patterson-Kane, Janet C. and McInnes, Iain B. and Brewer, James M. and Garside, Paul and Maffia, Pasquale (2016) Assessment of murine collagen-induced arthritis by longitudinal non-invasive duplexed molecular optical imaging. Rheumatology, 55 (3). pp. 565-572. ISSN 1462-0324

2014

Shrestha, Rajeev and Shakya Shrestha, S. and Millington, O. and Brewer, J. and Bushell, T. (2014) Immune responses in neurodegenerative diseases. Kathmandu University Medical Journal, 12 (45). pp. 67-76. ISSN 1812-2027

Shrestha Maleku, Rajeev and Millington, Owain and Brewer, James and Dev, Kumlesh and Bushell, Trevor (2014) Lymphocyte-mediated neuroprotection in in vitro models of excitotoxicity involves astrocytic activation and the inhibition of MAP kinase signalling pathways. Neuropharmacology, 76 (A). pp. 184-193. ISSN 0028-3908

2013

Stevenson, Ross and McAughtrie, Sarah and Senior, Laura and Stokes, Robert J and McGachy, Helen and Tetley, Laurence and Nativo, Paola and Brewer, James M and Alexander, James and Faulds, Karen and Graham, Duncan (2013) Analysis of intracellular enzyme activity by surface enhanced Raman scattering. Analyst, 138 (21). pp. 6331-6336.

2012

McQueenie, Ross and Stevenson, Ross and Benson, Robert and MacRitchie, Neil and McInnes, Iain and Maffia, Pasquale and Faulds, Karen and Graham, Duncan and Brewer, James and Garside, Paul (2012) Detection of inflammation in vivo by surface-enhanced Raman scattering provides higher sensitivity than conventional fluorescence imaging. Analytical Chemistry, 84 (14). pp. 5968-5975. ISSN 0003-2700

2011

Benson, R. A. and Patakas, A. and McQueenie, R. and Ross, K. and McInnes, I. B. and Brewer, J. M. and Garside, P. (2011) Arthritis in space and time - To boldly go! FEBS Letters, 585 (23). 3640–3648.

Ierna, Michelle and Smith, Karen and Ross, Kirsty and Meiklejohn, Gordon and Maffia, Pasquale and Brewer, James M. and McInnes, Iain B. and Garside, Paul (2011) Pre-clinical bioimaging in a mouse model of rheumatoid arthritis. Arthritis and Rheumatism, 63 (10). S75-S75. ISSN 0004-3591

Fumagalli, Stefano and Coles, Jonathan A and Ejlerskov, Patrick and Ortolano, Fabrizio and Bushell, Trevor J and Brewer, James M and De Simoni, Maria-Grazia and Dever, Gary and Garside, Paul and Maffia, Pasquale and Carswell, Hilary V (2011) In vivo real-time multiphoton imaging of T lymphocytes in the mouse brain after experimental stroke. Stroke, 42 (5). pp. 1429-1436. ISSN 0039-2499

Wright, A. J. and Benson, R. A. and Bowman, R. W. and Gibson, G. M. and Padgett, M. J. and Girkin, J. M. and Brewer, J. and Garside, P.; Dholakia, K. and Spalding, G.C., eds. (2011) Investigating the interaction forces between T cells and antigen-presenting cells using an optical trapping system. In: Optical trapping and optical micromanipulation VIII. Proceedings of SPIE . SPIE, Bellingham. ISBN 9780819487070

2010

Akbar, M. and Brewer, J.M. and Grant, M.H. (2010) Inflammatory response to orthopaedic cobalt chromium alloy wear debris in a rodent air pouch model. Toxicology Letters, 196S. S199. ISSN 0378-4274

Ortolano, F. and Maffia, Pasquale and Dever, G. and Rodolico, G. and Millington, O.R. and De Simoni, M.G. and Brewer, J.M. and Bushell, T. and Garside, P. and Carswell, H.V.O. (2010) Advances in imaging of new targets for pharmacological intervention in stroke : real time tracking of T cells in the ischaemic brain. British Journal of Pharmacology, 159 (4). pp. 808-811. ISSN 1476-5381

Millington, O.R. and Brewer, J.M. and Garside, P. and Maffia, P. (2010) Imaging interaction between the immune and cardiovascular systems in vivo by multiphoton microscopy. Methods in Molecular Biology, 161 (3). pp. 193-206.

Millington, O.R. and Brewer, J.M. and Garside, P. and Maffia, P. (2010) Imaging interactions between the immune and cardiovascular systems in vivo by multiphoton microscopy. Methods in Molecular Biology, 616. pp. 193-206. ISSN 1064-3745

Akbar, M. and Brewer, J.M. and Grant, M.H. (2010) Interaction of metal ions with human lymphocytes. In: 12th Meeting of the Combined Orthopaedic Associations, 1900-01-01.

2009

Rush, C.M. and Millington, O.R. and Hutchison, S. and Bryson, K. and Brewer, J.M. and Garside, P. (2009) Characterization of CD4+ T-cell–dendritic cell interactions during secondary antigen exposure in tolerance and priming. Immunology, 128 (4). pp. 463-471. ISSN 0019-2805

Dever, G.J. and Rodolico, G. and Berrino, L. and McInnes, I.B. and Brewer, J.M. and Garside, P. and Maffia, P. (2009) Three-dimensional imaging of atherosclerotic plaques in apolipoprotein e-deficient mice. Heart, 95 (22). ISSN 1468-201X

Ogunwale, B. and Schmidt-Ott, A. and Meek, R.M.D. and Brewer, J.M. (2009) Investigating the immunologic effects of cocr nanoparticles. Clinical Orthopaedics and Related Research, 467 (11). pp. 3010-3016. ISSN 0009-921X

Akbar, M. and Brewer, J.M. and Grant, M.H. (2009) Chromium and cobalt ions cause apoptosis in human lymphocytes in vitro. In: British Toxicology Annual Meeting, 2009-09-06 - 2009-09-07. (Unpublished)

Dever, G. and Rodolico, G. and Berrino, L. and McInnes, I.B. and Brewer, J.M. and Garside, P. and Maffia, P. (2009) Confocal and multiphoton laser scanning microscopy provide 3-dimensional imaging of atherosclerotic plaques in apolipoprotein e-deficient mice. Arteriosclerosis Thrombosis, and Vascular Biology, 29 (7). E74-E74. ISSN 1524-4636

Ortolano, F. and Maffia, Pasquale and Dever, G. and Hutchison, S. and Benson, R. and Millington, O.R. and De Simoni, M.G. and Bushell, T. and Garside, P. and Carswell, H.V. and Brewer, J.M. (2009) Imaging T-cell movement in the brain during experimental cerebral malaria. Parasite Immunology, 31 (3). pp. 147-150. ISSN 0141-9838

Jongbloed, S.L. and Benson, R.A. and Nickdel, M.B. and Garside, P. and McInnes, L.B. and Brewer, J.M. (2009) Plasmacytoid dendritic cells regulate breach of self-tolerance in autoimmune arthritis. Journal of Immunology, 182 (2). pp. 963-968. ISSN 0022-1767

Hutchison, S. and Choo-Kang, B.S.W. and Gibson, V.B. and Bundick, R.V. and Leishman, A.J. and Brewer, J.M. and McInnes, I.B. and Garside, P. (2009) An investigation of the impact of the location and timing of antigen-specific t cell division on airways inflammation. Clinical and Experimental Immunology, 155 (1). pp. 107-116. ISSN 0009-9104

2008

Benson, R.A. and Hutchison, S. and Millington, O.R. and McInnes, I.B. and Garside, P. and Brewer, J.M. (2008) Plasmacytoid dendritic cells and antigen presentation to CD4+t cells. Immunology, 125 (s1). p. 102. ISSN 0019-2805

Rush, C.M. and Bryson, K.J. and Hutchison, S. and Garside, P. and Brewer, J.M. (2008) Real time in vivo behaviour of CD4(+) T cells from naive, primed and orally tolerised mice during secondary antigen exposure. Immunology, 125 (s1). p. 76. ISSN 0019-2805

Nickdel, M.B. and Valesini, G. and Hutchison, S. and Benson, R. and Bundick, R.V. and Leishman, A.J. and McInnes, I.B. and Brewer, J.M. and Garside, P. (2008) Dissecting the contribution of innate and antigen-specific pathways to the breach of self-tolerance observed in a murine model of arthritis. Annals of the Rheumatic Diseases. ISSN 0003-4967

Culshaw, S. and Millington, O.R. and Brewer, J.M. and McInnes, I.B. (2008) Murine neutrophils present Class II restricted antigen. Immunology Letters, 118 (1). pp. 49-54. ISSN 0165-2478

Hutchison, S. and Choo-Kang, B.S.W. and Bundick, R.V. and Leishman, A.J. and Brewer, J.M. and McInnes, I.B. and Garside, P. (2008) Tumour necrosis factor-α blockade suppresses murine allergic airways inflammation. Clinical and Experimental Immunology, 151 (1). pp. 114-122. ISSN 0009-9104

Brewer, J.M. and Garside, P. (2008) Real-time imaging of the cellular interactions underlying tolerance, priming, and responses to infection. Immunological Reviews, 221 (1). pp. 130-146. ISSN 0105-2896

Thompson, J.G. and Millington, O.R. and Garside, P. and Brewer, J.M. (2008) What can transgenic parasites tell us about the development of Plasmodium-specific immune responses? Parasite Immunology, 30 (4). pp. 223-233. ISSN 0141-9838

2007

Wilson, Rona and Bate, Clive and Boshuizen, Ronald and Williams, Alun and Brewer, James (2007) Squalestatin alters the intracellular trafficking of a neurotoxic prion peptide. BMC Neuroscience, 8. 99. ISSN 1471-2202

Millington, Owain R. and Gibson, Vivienne B. and Rush, Catherine M. and Zinselmeyer, Bernd H. and Phillips, R. Stephen and Garside, Paul and Brewer, James M. (2007) Malaria impairs T cell clustering and immune priming despite normal signal 1 from dendritic cells. PLOS Pathogens, 3 (10). e143. ISSN 1553-7366

Maffia, Pasquale and Zinselmeyer, Bernd H. and Ialenti, Armando and Kennedy, Simon and Baker, Andrew H. and McInnes, Iain B. and Brewer, James M. and Garside, Paul (2007) Images in cardiovascular medicine : multiphoton microscopy for three-dimensional imaging of lymphocyte recruitment into apolipoprotein-E-deficient mouse carotid artery. Circulation, 115 (11). e326-e328. ISSN 0009-7322

Brewer, J.M. and Trif, M. and Roseanu, A. and Brock, J.H. (2007) Designing lipid nanostructures for local delivery of biologically active macromolecules. Journal of Liposome Research, 17 (3-4). pp. 237-248. ISSN 0898-2104

Brewer, J.M. and Millington, O.R. and Zinselmeyer, B.H. and Garside, P. and Rush, C. (2007) Lymphocyte tracking and interactions in secondary lymphoid organs. Inflammation Research, 56 (10). pp. 391-401. ISSN 1023-3830

2006

Millington, Owain R. and Di Lorenzo, Caterina and Phillips, R. Stephen and Garside, Paul and Brewer, James M. (2006) Suppression of adaptive immunity to heterologous antigens during plasmodium infection through hemozoin-induced failure of dendritic cell function. Journal of Biology, 5 (5). 5.

Garside, P. and Smith, K.M. and McNeil, R.C. and Brewer, J.M. (2006) Analysis of costimulatory molecule expression on antigen-specific T and B cells during the induction of adjuvant-induced th1 and th2 type responses. Vaccine, 24. pp. 3035-3043. ISSN 1873-2518

Brewer, J.M. (2006) (How) do aluminium adjuvants work? Immunology Letters, 102 (1). pp. 10-15. ISSN 0165-2478

Brewer, J.M. and Garside, P. and Rush, C.; Vella, Anthony T., ed. (2006) Investigating the contributions of inflammation and antigen depot to adjuvant function. In: Towards an Understanding of Initiating T Cell Immunity. Research Signpost, pp. 1-25. ISBN 9788130801186

Brewer, J.M. and Schneider, Helga and Downey, Jos and Smith, Andrew and Zinselmeyer, B.H. and Rush, Catherine (2006) Reversal of the TCR stop signal by CTLA-4. Science, 313 (5795). pp. 1972-1975. ISSN 0036-8075

Brewer, J.M. (2006) Using bicistronic IL-4 reporter mice to identify IL-4 expressing cells following immunisation with aluminium adjuvant. Vaccine, 24 (26). pp. 5393-5399. ISSN 1873-2518

2005

Zinselmeyer, B.H. and Dempster, J. and Gurney, A.M. and Wokosin, D.L. and Miller, M. and Ho, H. and Millington, O.R. and Smith, K.M. and Rush, C.M. and Parker, I. and Cahalan, M. and Brewer, J.M. and Garside, P. (2005) In situ characterisation of CD4+ t cell behaviour in mucosal and systemic lymphoid tissues during the induction of oral priming and tolerance. Journal of Experimental Medicine, 201 (11). pp. 1815-1823. ISSN 0022-1007

2004

Brewer, J.M. (2004) Vesicle size influences the trafficking, processing and presentation of antigens in lipid vesicles. Journal of Immunology, 173 (10). pp. 6143-6150. ISSN 0022-1767

Brewer, James M. and Smith, Karen M. and Rush, Catherine M. and Riley, Jillian and Garside, Paul (2004) In vivo generated Th1 cells can migrate to B cell follicles to support B cell responses. Journal of Immunology, 173 (3). pp. 1640-1646. ISSN 0022-1767

2003

Pollock, K.G.J. and McNeil, K.S. and Mottram, J.C. and Lyons, R.E. and Brewer, J.M. and Scott, P. and Coombs, G.H. and Alexander, J. (2003) The Leishmania mexicana cysteine protease, CPB2.8, induces potent Th2 responses. Journal of Immunology, 170 (4). pp. 1746-1753. ISSN 0022-1767

1995

Walker, W and Roberts, C W and Brewer, J M and Alexander, J (1995) Antibody responses to Toxoplasma gondii antigen in human peripheral blood lymphocyte-reconstituted severe-combined immunodeficient mice reproduce the immunological status of the lymphocyte donor. European Journal of Immunology, 25 (5). pp. 1426-1430. ISSN 0014-2980

Brewer, J M and Roberts, C W and Stimson, W H and Alexander, J (1995) Accurate determination of adjuvant-associated protein or peptide by ninhydrin assay. Vaccine, 13 (15). pp. 1441-1444. ISSN 1873-2518

1994

Roberts, C W and Brewer, J M and Alexander, J (1994) Congenital toxoplasmosis in the Balb/c mouse : prevention of vertical disease transmission and fetal death by vaccination. Vaccine, 12 (15). pp. 1389-1394. ISSN 1873-2518

Brewer, James and Roberts, Craig and O'Grady, J. E. and Smart, Christine and Alexander, James; (1994) Non-ionic surfactant vesicles as vaccine delivery systems. In: Biotechnology '94. The Institution of Chemical Engineers, Rugby, pp. 34-36. ISBN 9780852953358

1993

Alexander, J. and Roberts, C. W. and Brewer, J. M.; Smith, Judith E., ed. (1993) Progress towards the development of a vaccine against congenital toxoplasmosis : identification of protective antigens and the selection of appropriate adjuvants. In: Toxoplasmosis. Nato ASI Subseries H:, H78 . Springer-Verlag, Berlin, pp. 217-229. ISBN 9783642785610