Inflammatory response to orthopaedic cobalt chromium alloy wear debris in a rodent air pouch model

Akbar, M. and Brewer, J.M. and Grant, M.H. Inflammatory response to orthopaedic cobalt chromium alloy wear debris in a rodent air pouch model. Toxicology Letters, 196S. S199. ISSN 0378-4274

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Official URL: https://doi.org/10.1016/j.toxlet.2010.03.675

Abstract

Cobalt chromium (Co-Cr) alloy metal-on-metal (MOM) hip resurfacing has become increasingly common in younger, more active patients. However, there is growing concern regarding levels of Co-Cr wear debris and ions released. Using the rodent air pouch model, described as a facsimile synovium, we assessed the inflammatory response to artificially generated Co-Cr wear debris.

Author(s):	Akbar, M., Brewer, J.M. and Grant, M.H. ORCID: https://orcid.org/0000-0002-7712-404X
Item type:	Article
ID code:	28517
Keywords:	hip resurfacing, cobalt chromium, rodent air pouch, Bioengineering, Engineering (General). Civil engineering (General), Toxicology
Subjects:	Technology > Engineering (General). Civil engineering (General) > Bioengineering Technology > Engineering (General). Civil engineering (General)
Department:	Faculty of Engineering > Bioengineering Faculty of Science > Strathclyde Institute of Pharmacy and Biomedical Sciences
Depositing user:	Ms Ashley Urie
Date deposited:	28 Oct 2010 10:23
Last modified:	10 Jan 2020 02:22
URI:	https://strathprints.strath.ac.uk/id/eprint/28517
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