Plasmacytoid dendritic cells and antigen presentation to CD4+t cells
Benson, R.A. and Hutchison, S. and Millington, O.R. and McInnes, I.B. and Garside, P. and Brewer, J.M. (2008) Plasmacytoid dendritic cells and antigen presentation to CD4+t cells. Immunology, 125 (s1). p. 102. ISSN 0019-2805 (http://dx.doi.org/10.1111/j.1365-2567.2008.02974.x)
Full text not available in this repository.Request a copyAbstract
The enigmatic antigen presenting role of plasmacytoid dendritic cells (pDCs) has generated considerable interest in recent years. More recently,their interactions with CD4+ T cells and subsequent regulation of pathology in models of autoimmune disease have made them interesting targets for biological intervention. Our studies in a novel murine model of rheumatoid arthritis (RA), demonstrate that pDCs act to limit the spontaneous induction of auto-reactive T cell responses and autoantibody production and can limit the severity of pathology.
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Item type: Article ID code: 19303 Dates: DateEventDecember 2008PublishedSubjects: Science > Microbiology > Immunology
Medicine > Pharmacy and materia medica
Science > Natural history > BiologyDepartment: Faculty of Science > Strathclyde Institute of Pharmacy and Biomedical Sciences
Faculty of Science > Strathclyde Institute of Pharmacy and Biomedical Sciences > Centre for BiophotonicsDepositing user: Strathprints Administrator Date deposited: 18 May 2010 14:16 Last modified: 08 Apr 2024 17:43 URI: https://strathprints.strath.ac.uk/id/eprint/19303