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2013

Watson, David G and Tonelli, Francesca and Al Osaimi, Manal and Williamson, Leon and Chan, Edmond and Gorshkova, Irina and Berdyshev, Evgeny and Bittman, Robert and Pyne, Nigel J and Pyne, Susan (2013) The roles of sphingosine kinases 1 and 2 in regulating the Warburg effect in prostate cancer cells. Cellular Signalling, 25 (4). pp. 1011-1017. ISSN 1873-3913

Tonelli, F. and Alossaimi, M. and Williamson, L. and Tate, R.J. and Watson, D.G. and Chan, E. and Bittman, R. and Pyne, N.J. and Pyne, S. (2013) The sphingosine kinase inhibitor 2-(p-hyroxyanilino)-4-(p-chlorophenyl)thiazole reduces androgen receptor expression via an oxidative stress-dependent mechanism. British Journal of Pharmacology, 168 (6). pp. 1497-1505. ISSN 1476-5381

Tonelli, Francesca and Alossaimi, Manal and Natarajan, Viswanathan and Gorshkova, Irina and Berdyshev, Evgeny and Bittman, Robert and Watson, David G and Pyne, Susan and Pyne, Nigel J (2013) The roles of sphingosine kinase 1 and 2 in regulating the metabolome and survival of prostate cancer cells. Biomolecules, 3 (2). pp. 316-333. ISSN 2218-273X

2012

Lim, Keng Gat and Tonelli, Francesca Romana and Berdyshev, Evgeny and Gorshkova, Irina and Leclercq, Tamara and Pitson, Stuart M and Bittman, Robert and Pyne, Susan and Pyne, Nigel (2012) Inhibition kinetics and regulation of sphingosine kinase 1 expression in prostate cancer cells : functional differences between sphingosine kinase 1a and 1b. International Journal of Biochemistry and Cell Biology, 44 (9). pp. 1457-1464. ISSN 1357-2725

Pyne, Nigel J and Tonelli, Francesca and Lim, Keng Gat and Long, Jaclyn and Edwards, Joanne and Pyne, Susan (2012) Targeting sphingosine kinase 1 in cancer. Advances in Biological Regulation, 52 (1). 31–38. ISSN 2212-4934

2011

Lim, Keng and Tonelli, Francesca Romana and Li, Z. and Lu, X. and Bittman, R. and Pyne, Susan and Pyne, Nigel (2011) FTY720 analogues as sphingosine kinase 1 inhibitors : enzyme inhibition kinetics, allosterism, proteasomal degradation and actin rearrangement in MCF-7 breast cancer cells. Journal of Biological Chemistry, 286 (21). pp. 18633-18640. ISSN 1083-351X

2010

Loveridge, Carolyn and Tonelli, Francesca and Leclercq, Tamara and Lim, Keng Gat and Long, Jaclyn S and Berdyshev, Evgeny and Tate, Rothwelle J and Natarajan, Viswanathan and Pitson, Stuart M and Pyne, Nigel J and Pyne, Susan (2010) The sphingosine kinase 1 inhibitor 2-(P-hydroxyanilino)-4-(P-chlorophenyl)thiazole induces proteasomal degradation of sphingosine kinase 1 in mammalian cells. Journal of Biological Chemistry, 285 (50). pp. 38841-38852. ISSN 1083-351X

Tonelli, F. and Lim, K.G. and Loveridge, Carolyn and Long, J. and Pitson, S.M. and Tigyi, G. and Bittman, R. and Pyne, S. and Pyne, N.J. (2010) FTY720 and (S)-FTY720 vinylphosphonate inhibit sphingosine kinase 1 and promote its proteasomal degradation in human pulmonary artery smooth muscle, breast cancer and androgen-independent prostate cancer cells. Cellular Signalling, 22 (10). pp. 1536-1542. ISSN 1873-3913