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2024

Ali-Jerman, Hawraa and Al-Quraishi, Zainab and Muglikar, Ashish and Perrie, Yvonne and Tate, Rothwelle J. and Mullin, Margaret and McNeill, Gayle and MacKenzie, Graeme and Dufès, Christine (2024) Enhancing transfection efficacy in glioma cells : A comparison of microfluidic versus manual polypropylenimine dendriplex formation. International Journal of Nanomedicine, 19 (19). pp. 12189-12203. ISSN 1176-9114

Sliwowska, Joanna Helena and Woods, Nicola Elizabeth and Alzahrani, Abdullah Rzgallah and Paspali, Elpiniki and Tate, Rothwelle Joseph and Ferro, Valerie Anne (2024) Kisspeptin a potential therapeutic target in treatment of both metabolic and reproductive dysfunction. Journal of Diabetes, 16 (4). e13541. ISSN 1753-0407

Jenkinson, Mark R. J. and Meek, Dominic R. M. and Tate, Rothwelle and Brady, Adrian and MacMillan, Sandy and Grant, Helen and Currie, Susan (2024) Cardiac function may be compromised in patients with elevated blood cobalt levels secondary to metal-on-metal hip implants : a pilot study using a novel echocardiography measurement. The Bone & Joint Journal, 106-B (No.3 S). pp. 51-58. ISSN 2049-4394

2023

Maeyouf, Khadeejah and Sakpakdeejaroen, Intouch and Somani, Sukrut and Meewan, Jitkasem and Ali-Jerman, Hawraa and Laskar, Partha and Mullin, Margaret and MacKenzie, Graeme and Tate, Rothwelle J. and Dufès, Christine (2023) Transferrin-bearing, zein-based hybrid lipid nanoparticles for drug and gene delivery to prostate cancer cells. Pharmaceutics, 15 (11). 2643. ISSN 1999-4923

Jenkinson, Mark and Meek, Dominic and MacMillan, Sandy and Tate, Rothwelle and Grant, Mary and Currie, Susan (2023) Cardiac function is compromised in patients with elevated blood cobalt levels secondary to metal-on-metal hip implants. Heart, 109 (Supple). A4. ISSN 1468-201X

Olatunji, Zainab O and MacMillan, Sandy and Cameron-Ruiz, Miren and Bosakhar, Zainab Y and MacKenzie, Graeme and Grant, Mary H and Tate, Rothwelle and MacQuaide, Niall and Currie, Susan (2023) Effects of acute and chronic cobalt treatment on adult rat cardiomyocyte calcium handling. Heart, 109 (Supple). A6. ISSN 1468-201X

2022

Jenkinson, M. R.J. and Meek, R.M.D. and MacMillan, S. and Tate, R. and Grant, M.H. and Currie, S. (2022) Global longitudinal strain is compromised in patients with elevated blood cobalt levels secondary to metal-on-metal hip implants. In: Europhysiology 2022, 2022-09-16 - 2022-09-18, Tivoli Conference Centre.

Patkar, Shalmali and Uwanogho, Dafe and Modo, Michel and Tate, Rothwelle J. and Plevin, Robin and Carswell, Hilary V. O. (2022) Targeting 17β-estradiol biosynthesis in neural stem cells improves stroke outcome. Frontiers in Cellular Neuroscience, 16. 917181. ISSN 1662-5102

Almowalad, Jamal and Laskar, Partha and Somani, Sukrut and Meewan, Jitkasem and Tate, Rothwelle J. and Dufès, Christine (2022) Lactoferrin- and dendrimer-bearing gold nanocages for stimulus-free DNA delivery to prostate cancer cells. International Journal of Nanomedicine, 17. pp. 1409-1421. ISSN 1176-9114

Gómez-Arnaiz, Sara and Tate, Rothwelle J. and Grant, Mary Helen (2022) Cobalt neurotoxicity : transcriptional effect of elevated cobalt blood levels in the rodent brain. Toxics, 10 (2). 59. ISSN 2305-6304

2021

Almowalad, Jamal and Somani, Sukrut and Laskar, Partha and Meewan, Jitkasem and Tate, Rothwelle J. and Mullin, Margaret and Dufès, Christine (2021) Lactoferrin-bearing gold nanocages for gene delivery in prostate cancer cells in vitro. International Journal of Nanomedicine, 16. pp. 4391-4407. ISSN 1176-9114

Jenkinson, Mark R. J. and Meek, Dominic R. M. and Tate, Rothwelle and MacMillan, Sandy and Grant, M. Helen and Currie, Susan (2021) Cobalt-induced cardiomyopathy - do circulating cobalt levels matter? Bone and Joint Research, 10 (6). 340–347. ISSN 2046-3758

Brown, Ryan D.R. and Veerman, Ben E.P. and Oh, Jeongah and Tate, Rothwelle J. and Torta, Federico and Cunningham, Margaret R. and Adams, David R. and Pyne, Susan and Pyne, Nigel J. (2021) A new model for regulation of sphingosine kinase 1 translocation to the plasma membrane in breast cancer cells. Journal of Biological Chemistry. 100674. ISSN 1083-351X

Laskar, Partha and Somani, Sukrut and Mullin, Margaret and Tate, Rothwelle and Warzecha, Monika and Bowering, Deborah and Keating, Patricia and Irving, Craig and Leung, Hing Y and Dufès, Christine (2021) Octadecyl chain-bearing PEGylated poly(propyleneimine)-based dendrimersomes : physicochemical studies, redox-responsiveness, DNA condensation, cytotoxicity and gene delivery to cancer cells. Biomaterials Science, 9 (4). pp. 1431-1448. ISSN 2047-4830

2020

Gómez-Arnaiz, S. and Tate, R.J. and Grant, M.H. (2020) Cytotoxicity of cobalt chloride in brain cell lines - a comparison between astrocytoma and neuroblastoma cells. Toxicology in Vitro, 68. 104958. ISSN 0887-2333

Mazlan, Noor Wini and Tate, Rothwelle and Yusoff, Yusnaini Md. and Clements, Carol and Edrada-Ebel, RuAngelie (2020) Metabolomics-guided isolation of anti-trypanosomal compounds from endophytic fungi of the mangrove plant Avicennia lanata. Current Medicinal Chemistry, 27 (11). pp. 1815-1835. ISSN 0929-8673

2019

Laskar, Partha and Somani, Sukrut and Campbell, Sara Jane and Mullin, Margaret and Keating, Patricia and Tate, Rothwelle J. and Irving, Craig and Leung, Hing Y. and Dufès, Christine (2019) Camptothecin-based dendrimersomes for gene delivery and redox-responsive drug delivery to cancer cells. Nanoscale, 11 (42). pp. 20058-20071. ISSN 2040-3372

Neamatallah, Thikryat and Jabbar, Shilan and Tate, Rothwelle and Schroeder, Juliane and Shweash, Muhannad and Alexander, James and Plevin, Robin (2019) Whole genome microarray analysis of DUSP4-deletion reveals a novel role for MAP kinase phosphatase-2 (MKP-2) in macrophage gene expression and function. International Journal of Molecular Sciences, 20 (14). 3434. ISSN 1422-0067

Obeid, Mohammad A. and Dufès, Christine and Somani, Sukrut and Mullen, Alexander B. and Tate, Rothwelle J. and Ferro, Valerie A. (2019) Proof of concept studies for siRNA delivery by non-ionic surfactant vesicles : in vitro and in vivo evaluation of protein knockdown. Journal of Liposome Research, 29 (3). pp. 229-238. ISSN 0898-2104

2018

Laskar, Partha and Somani, Sukrut and Altwaijry, Najla Abdullah S and Mullin, Margaret and Bowering, Deborah and Warzecha, Monika and Keating, Patricia and Tate, Rothwelle J. and Leung, Hing Y. and Dufès, Christine (2018) Redox-sensitive, cholesterol-bearing PEGylated poly(propyleneimine)-based dendrimersomes for drug and gene delivery to cancer cells. Nanoscale, 10 (48). pp. 22830-22847. ISSN 2040-3372

Alyamani, Hanin and Obeid, Mohammad A and Tate, Rothwelle J and Ferro, Valerie A (2018) Exosomes : fighting cancer with cancer. Therapeutic Delivery, 10 (1). ISSN 2041-5990

Laovitthayanggoon, Sarunya and Henderson, Catherine J. and McCluskey, Claire and Macdonald, Margaret and Tate, Rothwelle J. and Grant, M. Helen and Currie, Susan (2018) Cobalt administration causes reduced contractility with parallel increases in TRPC6 and TRPM7 transporter protein expression in adult rat hearts. Cardiovascular Toxicology. ISSN 1559-0259

Alsanafi, Mariam and Kelly, Samuel L. and Jubair, Karawan and McNaughton, Melissa and Tate, Rothwelle J. and Merrill Jr., Alfred H. and Pyne, Susan and Pyne, Nigel J. (2018) Native and polyubiquitinated forms of dihydroceramide desaturase are differentially linked to human embryonic kidney cell survival. Molecular and Cellular Biology, 38. e00222. ISSN 0270-7306

Kouskou, Marianna and Thomson, David M. and Brett, Ros R. and Wheeler, Lee and Tate, Rothwelle J. and Pratt, Judith A. and Chamberlain, Luke H. (2018) Disruption of the Zdhhc9 intellectual disability gene leads to behavioural abnormalities in a mouse. Experimental Neurology, 308. pp. 35-46. ISSN 0014-4886

Kashmiry, Alaa and Tate, Rothwelle and Rotondo, Giuliana and Davidson, Jillian and Rotondo, Dino (2018) The prostaglandin EP4 receptor is a master regulator of the expression of PGE2 receptors following inflammatory activation in human monocytic cells. Biochimica et Biophysica Acta Molecular and Cell Biology of Lipids, 1863 (10). pp. 1297-1304. ISSN 1388-1981

Ritchie, Louise and Tate, Rothwelle and Chamberlain, Luke H. and Robertson, Graham and Zagnoni, Michele and Sposito, Teresa and Wray, Selina and Wright, John A. and Bryant, Clare E. and Gay, Nicholas J. and Bushell, Trevor J. (2018) Toll-like receptor 3 activation impairs excitability and synaptic activity via TRIF signalling in immature rat and human neurons. Neuropharmacology, 135. pp. 1-10. ISSN 0028-3908

El Buri, Ashref and Adams, David R. and Smith, Douglas and Tate, Rothwelle J. and Mullin, Margaret and Pyne, Susan and Pyne, Nigel J. (2018) The sphingosine 1-phosphate receptor 2 is shed in exosomes from breast cancer cells and is N-terminally processed to a short constitutively active form that promotes extracellular signal regulated kinase activation and DNA synthesis in fibroblasts. Oncotarget, 9 (50). pp. 29453-29467. ISSN 1949-2553

Altwaijry, Najla and Somani, Sukrut and Parkinson, John A. and Tate, Rothwelle J. and Keating, Patricia and Warzecha, Monika and MacKenzie, Graeme R. and Leung, Hing Y. and Dufès, Christine (2018) Regression of prostate tumors after intravenous administration of lactoferrin-bearing polypropylenimine dendriplexes encoding TNF-α, TRAIL and interleukin-12. Drug Delivery, 25 (1). pp. 679-689. ISSN 1521-0464

2017

Kakkassery, Vinodh and Skosyrski, S. and Lüth, A. and Kleuser, B. and van der Giet, M. and Tate, R. and Reinhard, J. and Faissner, A. and Joachim, S. C. and Kociok, N. (2017) Etoposide upregulates survival favoring sphingosine-1-phosphate in etoposide-resistant retinoblastoma cells. Pathology & Oncology Research. ISSN 1532-2807

Obeid, Mohammad A. and Elburi, Ashref and Young, Louise C. and Mullen, Alexander B. and Tate, Rothwelle J. and Ferro, Valerie A. (2017) Formulation of Nonionic Surfactant Vesicles (NISV) prepared by microfluidics for therapeutic delivery of siRNA into cancer cells. Molecular Pharmaceutics, 14 (7). pp. 2450-2458. ISSN 1543-8384

Tawfike, A F and Tate, R and Abbott, G and Young, L and Viegelmann, C and Schumacher, Marc and Diederich, Marc and Edrada-Ebel, R.A. (2017) Metabolomic tools to assess the chemistry and bioactivity of endophytic aspergillus strain. Chemistry and Biodiversity. ISSN 1612-1872

Berry, Helen R. and Tate, Rothwelle and Campbell, Conor and Conway, Bernard (2017) BDNF Val66Met polymorphism attenuates explosive jump fatigue differentially after trans-spinal anodal direct current stimulation. In: International Neuromodulation Society 13th World Congress, 2017-05-27 - 2017-06-01, Edinburgh International Conference Centre.

Berry, Helen R. and Tate, Rothwelle J. and Conway, Bernard A. (2017) Transcutaneous spinal direct current stimulation induces lasting fatigue resistance and enhances explosive vertical jump performance. PLOS One, 12 (4). e0173846. ISSN 1932-6203

Gomez Arnaiz, Sara and Tate, Rothwelle and Currie, Susan and Grant, Mary (2017) In vitro effects of cobalt ions on CNS derived cell lines. In: British Toxicology Society Congress 2017, 2017-04-03 - 2017-04-05, Hilton Hotel.

Laovitthayanggoon, Sarunya and Henderson, Catherine J. and Tate, Rothwelle J. and Currie, Susan and McCluskey, Claire and Macdonald, Margaret and Grant, M. Helen (2017) In vivo and in vitro toxicity of cobalt in the heart. In: British Toxicology Society Congress 2017, 2017-04-03 - 2017-04-05, Hilton Hotel.

Laovitthayanggoon, Sarunya and Grant, M. Helen and Henderson, Catherine J. and Tate, Rothwelle J. and Currie, Susan (2017) CoCl2 induced cardiotoxicity associated with CoCr alloy orthopaedic implants. Heart, 103 (S2). A4. 9. ISSN 1468-201X

Obeid, Mohammad A. and Gebril, Ayman M. and Tate, Rothwelle J. and Mullen, Alexander B. and Ferro, Valerie A. (2017) Comparison of the physical characteristics of monodisperse non-ionic surfactant vesicles (NISV) prepared using different manufacturing methods. International Journal of Pharmaceutics. pp. 1-23. ISSN 1873-3476

Obeid, Mohammad A. and Khadra, Ibrahim and Mullen, Alexander B. and Tate, Rothwelle J. and Ferro, Valerie A. (2017) The effects of hydration media on the characteristics of non-ionic surfactant vesicles (NISV) prepared by microfluidics. International Journal of Pharmaceutics, 516 (1-2). pp. 52-60. ISSN 1873-3476

2016

Woods, N and Gebril, A and Simpson, Ann and Iannetta, Ppm and Kenicer, G and Tate, R J and Pickard, B and Gray, A I and Ferro, V A (2016) Brain changing tubers : gene expression changes following mediaeval tuber consumption. Planta Medica, 81 (S 01). S1-S381. ISSN 0032-0943

Laovitthayanggoon, Sarunya and Grant, M. Helen and Henderson, Catherine J. and Tate, Rothwelle J. and Currie, Susan (2016) Investigating cobalt toxicity in the context of joint replacement patients - cobalt uptake in primary cardiac fibroblasts and in 3T3 cells. Applied in Vitro Toxicology, 2 (4). ISSN 2332-1539

Laovitthayanggoon, Sarunya and Tate, Rothwelle and Currie, Susan and Grant, Mary Helen (2016) Cobalt cardiotoxicity - effects on the contractile and non-contractile cells of the heart. FASEB Journal, 30 (1). 178.7. ISSN 0892-6638

2015

Lim, Li Ying and Koh, Pei Yin and Somani, Sukrut and Al Robaian, Majed and Karim, Reatul and Yean, Yi Lyn and Mitchell, Jennifer and Tate, Rothwelle J. and Edrada-Ebel, RuAngelie and Blatchford, David R. and Mullin, Margaret and Dufès, Christine (2015) Tumor regression following intravenous administration of lactoferrin- and lactoferricin-bearing dendriplexes. Nanomedicine: Nanotechnology, Biology and Medicine, 11 (6). pp. 1445-1454. ISSN 1549-9634

Posada, Olga M. and Tate, Rothwelle J. and Meek, R.M. Dominic and Grant, M. Helen (2015) In vitro analyses of the toxicity, immunological, and gene expression effects of cobalt-chromium alloy wear debris and Co ions derived from metal-on-metal hip implants. Lubricants, 3 (3). pp. 539-568.

Tate, Rothwelle and Rotondo, Dino and Davidson, Jillian (2015) Regulation of lipid metabolism by microRNAs. Current Opinion in Lipidology, 26 (3). pp. 243-244. ISSN 0957-9672

Posada, Olga M. and Tate, R. J. and Grant, M. H. (2015) Toxicity of cobalt-chromium nanoparticles released from a resurfacing hip implant and cobalt ions on primary human lymphocytes in vitro. Journal of Applied Toxicology, 35 (6). pp. 614-622. ISSN 0260-437X

Posada, Olga M. and Tate, Rothwelle J. and Grant, M. Helen (2015) Effects of CoCr metal wear debris generated from metal-on-metal hip implants and Co ions on human monocyte-like U937 cells. Toxicology in Vitro, 29 (2). pp. 271-280. ISSN 0887-2333

Philip, Anna and Ferro, Valerie A. and Tate, Rothwelle J. (2015) Determination of the potential bioavailability of plant microRNAs using a simulated human digestion process. Molecular Nutrition and Food Research. ISSN 1613-4125

2014

Posada, Olga M. and Gilmour, Denise and Tate, Rothwelle J. and Grant, M. Helen (2014) CoCr wear particles generated from CoCr alloy metal-on-metal hip replacements, and cobalt ions stimulate apoptosis and expression of general toxicology-related genes in monocyte-like U937 cells. Toxicology and Applied Pharmacology, 281 (1). 125–135. ISSN 0041-008X

Tawfike, Ahmed Fares and Edrada-Ebel, Ruangelie and Tate, Roth and Diederich, Marc and Schumacher, Marc and Sawadogo, Richard and Clements, Carol and Young, Louise (2014) Metabolomics and dereplication studies of endophytic metabolites from some Egyptian medicinal plants in the search potential antimicrobial drugs. In: Metabolomics 2014, 2014-06-23 - 2014-06-26, Daiichi Hotel Tsuruoka and Marica/Washington Hotel.

2013

Davidson, Jillian and Tate, Rothwelle and Rotondo, Dino (2013) Genetics and molecular biology : the role of retinoic acid receptor genes in acute promyelocytic leukemia. Current Opinion in Lipidology, 24 (4). pp. 364-365. ISSN 0957-9672

Posada Estefan, Olga Maria and Grant, Helen and Tate, Rothwelle J. (2013) Co–Cr wear products derived from metal-on-metal articulations induce apoptosis on monocyte-like U937 cells. Toxicology Letters, 28 (Suppl). S75. ISSN 0378-4274

Noor Wini Binti Mazlan, N and Tate, Rothwelle and Clements, Carol and Edrada-Ebel, Ruangelie (2013) Metabolomics studies of endophytic metabolites from Malaysian mangrove plant in the search for new potential antibiotics. Planta Medica, 79 (13). PA22. ISSN 0032-0943

Posada Estefan, Olga Maria and Tate, Rothwelle and Grant, Mary (2013) Co-Cr wear particles and cobalt ions stimulate the expression of human general toxicology related genes on monocyte like U937 cells. In: British Toxicology Society Meeting, 2013-04-07 - 2013-04-10.

Tonelli, F. and Alossaimi, M. and Williamson, L. and Tate, R.J. and Watson, D.G. and Chan, E. and Bittman, R. and Pyne, N.J. and Pyne, S. (2013) The sphingosine kinase inhibitor 2-(p-hyroxyanilino)-4-(p-chlorophenyl)thiazole reduces androgen receptor expression via an oxidative stress-dependent mechanism. British Journal of Pharmacology, 168 (6). pp. 1497-1505. ISSN 1476-5381

Gibriel, Abdullah and Tate, Rothwelle and Yu, Yongbin and Rawson-Lax, E. and Hammer, HM and Tettey, Justice Nii Addy and Pyne, Nigel and Converse, Carolyn (2013) The p.Arg86Gln change in GARP2 (glutamic acid-rich protein-2) is a common West African-related polymorphism. Gene, 515 (1). pp. 155-158. ISSN 0378-1119

2012

Tawfike, Ahmed Fares Said and Romli, Mohamed and Tate, Rothwelle and Diederich, Marc and Schumacher, Marc and Edrada-Ebel, Ruangelie (2012) Metabolomics and dereplication studies of endophytic metabolites from some Egyptian medicinal plants in search for new potential anti-cancer drugs. In: Metabomeeting 2012, 2012-09-21 - 2012-09-24, University of Manchester.

Patkar, Shalmali Satish and Tate, Rothwelle and Modo, M. and Plevin, Robin and Carswell, Hilary (2012) Conditionally immortalised neural stem cells promote functional recovery and brain plasticity after transient focal cerebral ischaemia in mice. Stem Cell Research, 8 (1). 14–25.

Lemarié, Fanny and Croft, Daniel and Tate, Rothwelle and Ryan, Kevin M. and Dufès, Christine (2012) Tumor regression following intravenous administration of a tumor-targeted p73 gene delivery system. Biomaterials, 33. pp. 2701-2709. ISSN 1878-5905

2011

Aldawsari, Hibah Mobarak and Edrada-Ebel, Ruangelie and Blatchford, David and Tate, Rothwelle and Tetley, Laurence and Dufès, Christine (2011) Enhanced gene expression in tumors after intravenous administration of arginine-, lysine- and leucine-bearing polypropylenimine polyplex. Biomaterials, 32 (25). pp. 5889-5899. ISSN 1878-5905

Posada Estefan, Olga Maria and Tate, Rothwelle and Grant, Mary (2011) RNA stability in frozen/thawed clinical samples. In: The 6th UK and RI Postgraduate Conference in Biomedical Engineering and Medical Physics, 2011-08-14 - 2011-08-16.

Aldawsari, Hibah Mobarak and Sundara Raj, Behin and Edrada-Ebel, Ruangelie and Blatchford, David and Tate, Rothwelle and Tetley, Laurence and Dufès, Christine (2011) Enhanced gene expression in tumors after intravenous administration of arginine-, lysine- and leucine-bearing polyethylenimine polyplex. Nanomedicine: Nanotechnology, Biology and Medicine, 7 (5). pp. 815-823.

Posada Estefan, Olga Maria and Tate, Rothwelle and Grant, Mary (2011) RNA stability in frozen/thawed clinical blood samples. In: British Toxicology Society Meeting, 2011-09-05 - 2011-09-06.

2010

Loveridge, Carolyn and Tonelli, Francesca and Leclercq, Tamara and Lim, Keng Gat and Long, Jaclyn S and Berdyshev, Evgeny and Tate, Rothwelle J and Natarajan, Viswanathan and Pitson, Stuart M and Pyne, Nigel J and Pyne, Susan (2010) The sphingosine kinase 1 inhibitor 2-(P-hydroxyanilino)-4-(P-chlorophenyl)thiazole induces proteasomal degradation of sphingosine kinase 1 in mammalian cells. Journal of Biological Chemistry, 285 (50). pp. 38841-38852. ISSN 1083-351X

Koppu, Swati and Oh, Yew Jinn and Edrada-Ebel, R. and Blatchford, David R. and Tetley, L. and Tate, R. and Dufès, Christine (2010) Tumor regression after systemic administration of a novel tumor-targeted gene delivery system carrying a therapeutic plasmid DNA. Journal of Controlled Release, 143 (2). pp. 215-221. ISSN 0168-3659

Aldawsari, Hibah Mobarak and Sundara Raj, Behin and Edrada-Ebel, Ruangelie and Blatchford, David and Tate, Rothwelle and Dufès, Christine (2010) Enhanced transfection efficacy of polyethylenimine by surface modification with arginine, lysine, and leucine. Controlled Release Society Newsletter, 27 (6). pp. 12-14.

2009

Patkar, S. and Tate, R. and Modo, M. and Plevin, R.J. and Carswell, H.V.O. (2009) Characterisation of neural stem cells for oestrogen in vitro: potential for improving stem cell based therapy for stroke. Journal of Cerebral Blood Flow and Metabolism, 29. S554-S555.

Wheate, N.J. and Abbott, Grainne M. and Tate, Rothwelle J. and Clements, Caorl J. and Edrada-Ebel, RuAngelie and Johnston, B.F. (2009) Side-on binding of p-sulphonatocalix[4]arene to the dinuclear platinum complex trans-[{PtCl(NH3)2}2μ-dpzm]2+ and its implications for anticancer drug delivery. Journal of Inorganic Biochemistry, 103 (3). pp. 448-454. ISSN 0162-0134

2008

Mooney, M.H. and Fogarty, S. and Stevenson, C. and Gallagher, A.M. and Palit, P. and Hawley, S.A. and Hardie, D.G. and Coxon, Geoffrey and Waigh, Roger and Tate, R. and Harvey, Alan and Furman, Brian (2008) Mechanisms underlying the metabolic actions of galegine that contribute to weight loss in mice. British Journal of Pharmacology, 153 (8). pp. 1669-1677. ISSN 1476-5381

2007

Gopal, P. and Tate, R. and Pow, E. and Hill, D. and Connolly, J.G. (2007) The role of the amino acid residue at α1:189 in the binding of neuromuscular blocking agents to mouse and human muscle nicotinic acetylcholine receptors. British Journal of Pharmacology, 150 (7). pp. 920-931. ISSN 1476-5381

2006

Egan, C.A. and Houston, K.M. and Alcocer, M.J.C. and Solovyova, A. and Tate, R. and Lochnit, G. and McInnes, I.B. and Harnett, M.M. (2006) Lack of immunological cross-reactivity between parasite-derived and recombinant forms of es-62, a secreted protein of acanthocheilonema viteae. Parasitology, 132 (2). pp. 263-274. ISSN 0031-1820

Pyne, N.J. and Murray, Fiona and Tate, R. and MacLean, Margaret R; Beavo, J and Francis, S and Houslay, MD, eds. (2006) Molecular determinants in pulmonary hypertension : the role of PDE5. In: Cyclic Nucleotide Phosphodiesterases in Health and Diseases. CRC/Taylor & Francis Group, Boca Raton, pp. 501-518. ISBN 9780849396687

2003

Frame, Mhairi J and Tate, Rothwelle and Adams, David R and Morgan, Keith M and Houslay, M D and Vandenabeele, Peter and Pyne, Nigel J (2003) Interaction of caspase-3 with the cyclic GMP binding cyclic GMP specific phosphodiesterase (PDE5a1). European Journal of Biochemistry, 270 (5). pp. 962-970. ISSN 0014-2956

Gurney, A.M. and Osipenko, O.N. and MacMillan, D. and McFarlane, K.M. and Tate, R.J.S.J. and Kempsill, F.E.J. (2003) Two-pore domain k channel, TASK-1, in pulmonary artery smooth muscle cells. Circulation Research, 93. pp. 957-964. ISSN 0009-7330

Wan, K.F. and Sambi, B.S. and Tate, R. and Waters, C. and Pyne, N.J. (2003) The inhibitory gamma subunit of the type 6 retinal cGMP phosphodiesterase functions to link c-Src and g-protein-coupled receptor kinase 2 in a signaling unit that regulates p42/p44 mitogen-activated protein kinase by epidermal growth factor. Journal of Biological Chemistry, 278. pp. 18658-18663. ISSN 1083-351X

2002

Stepek, G and Auchie, M and Tate, R and Watson, K and Russell, D G and Devaney, E and Harnett, W (2002) Expression of the filarial nematode phosphorylcholine-containing glycoprotein, ES62, is stage specific. Parasitology, 125 (Pt 2). pp. 155-64. ISSN 0031-1820

Connolly, John G. and Tate, Roth J. and McLennan, Neil F. and Brown, Debbie and Telling, Glenn C. and Fraser, Jan and Head, Mark W. (2002) Properties of the cellular prion protein expressed in Xenopus oocytes. NeuroReport, 13 (9). pp. 1229-1233. ISSN 0959-4965

Tate, R. and Arshavsky, V.Y. and Pyne, N.J. (2002) The identification of the inhibitory gamma-subunits of the type 6 retinal cyclic guanosine monophosphate phosphodiesterase in non-retinal tissues: differential processing of mRNA transcripts. Genomics, 79 (4). pp. 582-586. ISSN 1089-8646

2001

Frame, Mhairi and Wan, Kah Fei and Tate, R. and Vandenabeele, Peter and Pyne, Nigel J. (2001) The gamma subunit of the rod photoreceptor cGMP phosphodiesterase can modulate the proteolysis of two cGMP binding cGMP-specific phosphodiesterases (PDE6 and PDE5) by caspase-3. Cellular Signalling, 13 (10). pp. 735-741. ISSN 1873-3913

Alderton, F. and Sambi, B.S. and Tate, R. and Pyne, N.J. and Pyne, S. (2001) Assessment of agonism at g-protein coupled receptors by phosphatidic acid and lysophosphatidic acid in human embryonic kidney 293 cells. British Journal of Pharmacology, 134 (1). pp. 6-9. ISSN 1476-5381

Wan, K.F. and Sambi, B.S. and Frame, M.J. and Tate, R. and Pyne, N.J. (2001) The inhibitory gamma subunit of the type 6 retinal cyclic guanosine monophosphate phosphodiesterase is a novel intermediate regulating p42/p44 mitogen-activated protein kinase signaling in human embryonic kidney 293 cells. Journal of Biological Chemistry, 276 (41). pp. 37794-37802. ISSN 1083-351X

2000

Ahmad, M and Abdel-Wahab, Y H and Tate, R and Flatt, P R and Pyne, N J and Furman, B L (2000) Effect of type-selective inhibitors on cyclic nucleotide phosphodiesterase activity and insulin secretion in the clonal insulin secreting cell line BRIN-BD11. British Journal of Pharmacology, 129 (6). pp. 1228-1234. ISSN 1476-5381

Osipenko, O N and Tate, R J and Gurney, A M and Tate, Rothwelle (2000) Potential role for kv3.1b channels as oxygen sensors. Circulation Research, 86 (5). pp. 534-40. ISSN 0009-7330

1999

Pyne, S and Rakhit, S and Conway, A M and McKie, A and Darroch, P and Tate, R and Pyne, N (1999) Extracellular actions of sphingosine 1-phosphate through endothelial differentiation gene products in mammalian cells: role in regulating proliferation and apoptosis. Biochemical Society Transactions, 27 (4). pp. 404-409. ISSN 0300-5127

Rakhit, S and Conway, A M and Tate, R and Bower, T and Pyne, N J and Pyne, S (1999) Sphingosine 1-phosphate stimulation of the p42/p44 mitogen-activated protein kinase pathway in airway smooth muscle. Role of endothelial differentiation gene 1, c-Src tyrosine kinase and phosphoinositide 3-kinase. Biochemical journal, 338 (3). pp. 643-649. ISSN 0264-6021

Tate, R J and Tolan, D and Pyne, S (1999) Molecular cloning of magnesium-independent type 2 phosphatidic acid phosphatases from airway smooth muscle. Cellular Signalling, 11 (7). pp. 515-522. ISSN 1873-3913

1998

Tate, R J and Lochhead, A and Brzeski, H and Arshavsky, V and Pyne, N J (1998) The gamma-subunit of the rod photoreceptor cGMP-binding cGMP-specific PDE is expressed in mouse lung. Cell Biochemistry and Biophysics, 29 (1-2). pp. 133-144. ISSN 1085-9195

1997

Somiari, R I and Brzeski, H and Tate, R and Bieleck, S and Polak, J (1997) Cloning and sequencing of an aspergillus niger gene coding for beta-fructufuranosidase. Biotechnology Letters, 19 (12). pp. 1243-1247. ISSN 0141-5492

Habib, F K and Ross, M and Tate, R and Chisholm, G D (1997) Differential effect of finasteride on the tissue androgen concentrations in benign prostatic hyperplasia. Clinical Endocrinology, 46 (2). pp. 137-44. ISSN 0300-0664

1996

Belham, C M and Tate, R J and Scott, P H and Pemberton, A D and Miller, H R and Wadsworth, R M and Gould, G W and Plevin, R (1996) Trypsin stimulates proteinase-activated receptor-2-dependent and -independent activation of mitogen-activated protein kinases. Biochemical journal, 320 ( Pt . pp. 939-46. ISSN 0264-6021

1995

Iehlé, Catherine and Délos, Sylvie and Guirou, Olivier and Tate, Rothwell and Raynaud, Jean-Pierre and Martin, Pierre-Marie (1995) Human prostatic steroid 5 alpha-reductase isoforms--a comparative study of selective inhibitors. Journal of Steroid Biochemistry and Molecular Biology, 54 (5-6). pp. 273-279. ISSN 0960-0760

1993

Heyns, C F and Tate, R and Sargent, N S and Habib, F K and Chisholm, G D (1993) Absence of 5 alpha-reductase activity in the gubernaculum during descent of the fetal pig testis. Journal of Urology, 150 (2 Pt 1). pp. 510-513. ISSN 0022-5347