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2024
Armstrong, Georgina Bethany and Burley, Glenn A. and Lewis, William and Rattray, Zahra (2024) Assessing the manufacturability and critical quality attribute profiles of anti-IL-8 immunoglobulin G mutant variants. Molecular Pharmaceutics, 21 (12). 6423–6432. ISSN 1543-8384
2023
Rodrigues, Miguel A. and Matsarskaia, Olga and Rego, Pedro and Geraldes, Vitor and Connor, Lauren E. and Oswald, Iain D. H. and Sztucki, Michael and Shalaev, Evgenyi (2023) Freeze-induced phase transition and local pressure in a phospholipid/water system : novel insights from a time/temperature resolved synchrotron X-ray diffraction study. Molecular Pharmaceutics, 20 (11). pp. 5790-5799. ISSN 1543-8384
2022
Charpentier, Maxime D. and Venkatramanan, Raghunath and Rougeot, Céline and Leyssens, Tom and Johnston, Karen and ter Horst, Joop H. (2022) Multicomponent chiral quantification with Ultraviolet circular dichroism spectroscopy : ternary and quaternary phase diagrams of Levetiracetam. Molecular Pharmaceutics, 20 (1). pp. 616-629. ISSN 1543-8384
Webb, Cameron and Ip, Shell and Bathula, Nuthan V. and Popova, Petya and Soriano, Shekinah K. V. and Ly, Han Han and Eryilmaz, Burcu and Nguyen Huu, Viet Anh and Broadhead, Richard and Rabel, Martin and Villamagna, Ian and Abraham, Suraj and Raeesi, Vahid and Thomas, Anitha and Clarke, Samuel and Ramsay, Euan C. and Perrie, Yvonne and Blakney, Anna K. (2022) Current status and future perspectives on MRNA drug manufacturing. Molecular Pharmaceutics, 19 (4). pp. 1047-1058. ISSN 1543-8384
2021
Chatzikleanthous, Despo and O'Hagan, Derek T and Adamo, Roberto (2021) Lipid-based nanoparticles for delivery of vaccine adjuvants and antigens : toward multicomponent vaccines. Molecular Pharmaceutics, 18 (8). pp. 2867-2888. ISSN 1543-8384
2019
Harfouche, Lina C. and Brandel, Clément and Cartigny, Yohann and Ter Horst, Joop H. and Coquerel, Gérard and Petit, Samuel (2019) Enabling direct preferential crystallization in a stable racemic compound system. Molecular Pharmaceutics, 16 (11). pp. 4670-4676. ISSN 1543-8384
Bordos, Ecaterina and Islam, Muhammad T. and Florence, Alastair J. and Halbert, Gavin W. and Robertson, John (2019) Use of terahertz-Raman spectroscopy to determine solubility of the crystalline active pharmaceutical ingredient in polymeric matrices during hot melt extrusion. Molecular Pharmaceutics, 16 (10). pp. 4361-4371. ISSN 1543-8384
Roces, Carla B. and Khadke, Swapnil and Christensen, Dennis and Perrie, Yvonne (2019) Scale-independent microfluidic production of cationic liposomal adjuvants and development of enhanced lymphatic targeting strategies. Molecular Pharmaceutics, 16 (10). pp. 4372-4386. ISSN 1543-8384
Dunn, Claire and Perrier, Jeremy and Khadra, Ibrahim and Wilson, Clive G. and Halbert, Gavin W. (2019) The topography of simulated intestinal equilibrium solubility. Molecular Pharmaceutics, 16 (5). pp. 1890-1905. ISSN 1543-8384
2018
Smith, Lindsay and Serrano, Dolores R. and Mauger, Marion and Bolás-Fernández, Francisco and Dea-Ayuela, Maria Auxiliadora and Lalatsa, Aikaterini (2018) Orally bioavailable and effective buparvaquone lipid-based nanomedicines for visceral leishmaniasis. Molecular Pharmaceutics, 15 (7). pp. 2570-2583. ISSN 1543-8384
2017
Ainousah, Bayan E and Perrier, Jeremy and Dunn, Claire and Khadra, Ibrahim and Wilson, Clive G. and Halbert, Gavin W (2017) Dual level statistical investigation of equilibrium solubility in simulated fasted and fed intestinal fluid. Molecular Pharmaceutics, 14 (12). pp. 4170-4180. ISSN 1543-8384
Zhou, Zhou and Dunn, Claire and Khadra, Ibrahim and Wilson, Clive G. and Halbert, Gavin W. (2017) Influence of physiological gastrointestinal surfactant ratio on the equilibrium solubility of BCS class II drugs investigated using a four component mixture design. Molecular Pharmaceutics. ISSN 1543-8384
Obeid, Mohammad A. and Elburi, Ashref and Young, Louise C. and Mullen, Alexander B. and Tate, Rothwelle J. and Ferro, Valerie A. (2017) Formulation of Nonionic Surfactant Vesicles (NISV) prepared by microfluidics for therapeutic delivery of siRNA into cancer cells. Molecular Pharmaceutics, 14 (7). pp. 2450-2458. ISSN 1543-8384
Rolón, Miriam and Serrano, Dolores R. and Lalatsa, Aikaterini and De Pablo, Esther and Torrado, Juan Jose and Ballesteros, Maria Paloma and Healy, Anne Marie and Vega, Celeste and Coronel, Cathia and Bolás-Fernández, Francisco and Dea-Ayuela, Maria Auxiliadora (2017) Engineering oral and parenteral amorphous amphotericin B formulations against experimental Trypanosoma cruzi infections. Molecular Pharmaceutics, 14 (4). pp. 1095-1106. ISSN 1543-8384
2015
Palmer, David S. and Misin, Maksim and Fedorov, Maxim V. and Llinas, Antonio (2015) Fast and general method to predict the physicochemical properties of druglike molecules using the integral equation theory of molecular liquids. Molecular Pharmaceutics, 12 (9). 3420–3432. ISSN 1543-8384
Serrano, Dolores R. and Lalatsa, Aikaterini and Dea-Ayuela, M. Auxiliadora and Bilbao-Ramos, Pablo E. and Garrett, Natalie L. and Moger, Julian and Guarro, Josep and Capilla, Javier and Ballesteros, M. Paloma and Schätzlein, Andreas G. and Bolás, Francisco and Torrado, Juan J. and Uchegbu, Ijeoma F. (2015) Oral particle uptake and organ targeting drives the activity of amphotericin B nanoparticles. Molecular Pharmaceutics, 12 (2). pp. 420-431. ISSN 1543-8384
2014
Palmer, David S. and Mitchell, John B. O. (2014) Is experimental data quality the limiting factor in predicting the aqueous solubility of druglike molecules? Molecular Pharmaceutics, 11 (8). 2962–2972. ISSN 1543-8384
Lalatsa, Aikaterini and Schatzlein, Andreas G. and Uchegbu, Ijeoma F. (2014) Strategies to deliver peptide drugs to the brain. Molecular Pharmaceutics, 11 (4). pp. 1081-1093. ISSN 1543-8384
Kaur, Randip and Henriksen-Lacey, Malou and Wilkhu, Jitinder and Devitt, Andrew and Christensen, Dennis and Perrie, Yvonne (2014) Effect of incorporating cholesterol into DDA:TDB liposomal adjuvants on bilayer properties, biodistribution, and immune responses. Molecular Pharmaceutics, 11 (1). pp. 197-207. ISSN 1543-8384
2013
Onyesome, Ichioma and Lamprou, Dimitrios and Sygellou, Lamprini and Owusu-Ware, Samuel and Antonijevic, Milan and Chowdhry, Babur and Douroumis, D. (2013) Sirolimus encapsulated liposomes for cancer therapy : physicochemical and mechanical characterization of sirolimus distribution within liposome bilayers. Molecular Pharmaceutics, 10 (11). pp. 4281-4293. ISSN 1543-8384
2011
Palmer, David and Frolov, Andrey I. and Ratkova, Ekaterina L. and Fedorov, Maxim V. (2011) Toward a universal model to calculate the solvation thermodynamics of druglike molecules : the importance of new experimental databases. Molecular Pharmaceutics, 8 (4). pp. 1423-1429.
2010
Walker, Shonagh and Kaur, Rajdip and McInnes, Fiona J and Wheate, Nial J (2010) Synthesis, processing and solid state excipient interactions of cucurbit[6]uril and its formulation into tablets for oral drug delivery. Molecular Pharmaceutics, 7 (6). pp. 2166-2172.