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2015

Gomez-Roman, Natividad and McGregor, Fiona and Wheate, Nial J. and Plumb, Jane A. (2015) Cucurbit [7] uril encapsulated cisplatin overcomes resistance to cisplatin induced by Rab25 overexpression in an intraperitoneal ovarian cancer model. Journal of Ovarian Research, 8 (1). pp. 1-10. 62. ISSN 1757-2215

2014

Oun, Rabbab and Floriano, Rafael S. and Isaacs, Lyle and Rowan, Edward G. and Wheate, Nial J. (2014) The ex vivo neurotoxic, myotoxic and cardiotoxic activity of cucurbituril-based macrocyclic drug delivery vehicles. Toxicology Research, 3 (6). pp. 447-455. ISSN 2045-4538

Oun, Rabbab and Plumb, Jane A. and Wheate, Nial J. (2014) A cisplatin slow-release hydrogel drug delivery system based on a formulation of the macrocycle cucurbit[7]uril, gelatin and polyvinyl alcohol. Journal of Inorganic Biochemistry, 134. pp. 100-105. ISSN 0162-0134

2012

Craig, Gemma E. and Brown, Sarah D. and Lamprou, Dimitrios A. and Graham, Duncan and Wheate, Nial J. (2012) Cisplatin-tethered gold nanoparticles that exhibit enhanced reproducibility, drug loading, and stability : a step closer to pharmaceutical approval? Inorganic Chemistry, 51 (6). pp. 3490-3497. ISSN 1520-510X

Alniss, Hasan Y and Anthony, Nahoum Guillaume Husan and Khalaf, Abedawn and Mackay, Simon and Suckling, Colin and Waigh, Roger and Wheate, Nial and Parkinson, John (2012) Rationalising sequence selection by ligand assemblies in the DNA minor groove : the case for thiazotropsin A. Chemical Science, 3 (3). pp. 711-722. ISSN 2041-6539

2011

Kirkpatrick, Gordon J and Plumb, Jane A and Sutcliffe, Oliver B and Flint, David J and Wheate, Nial J (2011) Evaluation of anionic half generation 3.5-6.5 poly(amidoamine) dendrimers as delivery vehicles for the active component of the anticancer drug cisplatin. Journal of Inorganic Biochemistry, 105 (9). pp. 1115-1122.

Walker, Shonagh and Oun, Rabbab and Mcinnes, Fiona and Wheate, Nial (2011) The potential of cucurbit[n]urils in drug delivery. Israel Journal of Chemistry, 51 (5-6). pp. 616-624.

2010

Wheate, N.J. and Vora, V. and Anthony, N.G. and McInnes, F.J. (2010) Host-guest complexes of the antituberculosis drugs pyrazinamide and isoniazid with cucurbit[7]uril. Journal of Inclusion Phenomena and Macrocyclic Chemistry, 68 (3-4). pp. 359-367. ISSN 0923-0750

Walker, Shonagh and Kaur, Rajdip and McInnes, Fiona J and Wheate, Nial J (2010) Synthesis, processing and solid state excipient interactions of cucurbit[6]uril and its formulation into tablets for oral drug delivery. Molecular Pharmaceutics, 7 (6). pp. 2166-2172.

Brown, Sarah D. and Nativo, Paola and Smith, Jo-Ann and Stirling, David and Edwards, Paul R. and Venugopal, Balaji and Flint, David J. and Plumb, Jane A. and Graham, Duncan and Wheate, Nial J. (2010) Gold nanoparticles for the improved anticancer drug delivery of the active component of oxaliplatin. Journal of the American Chemical Society, 132 (13). pp. 4678-4684. ISSN 1520-5126

Wheate, N.J. and Patel, Nilesh and Sutcliffe, O.B. (2010) Microwave synthesis of curcurbit[n]urils. Future Medicinal Chemistry, 2 (2). pp. 231-236. ISSN 1756-8919

McInnes, F.J. and Anthony, N.G. and Kennedy, Alan R. and Wheate, Nial J. (2010) Solid state stabilisation of the orally delivered drugs atenolol, glibenclamide, memantine and paracetamol through their complexation with cucurbit[7]uril. Organic and Biomolecular Chemistry, 8 (4). pp. 765-773. ISSN 1477-0520

2009

Kennedy, Alan R. and Florence, Alastair J. and McInnes, Fiona J. and Wheate, Nial J. (2009) A chemical preformulation study of a host-guest complex of cucurbit[7]uril and a multinuclear platinum agent for enhanced anticancer drug delivery. Dalton Transactions, 2009 (37). pp. 7695-7700. ISSN 1472-7773

Wheate, N.J. and Abbott, Grainne M. and Tate, Rothwelle J. and Clements, Caorl J. and Edrada-Ebel, RuAngelie and Johnston, B.F. (2009) Side-on binding of p-sulphonatocalix[4]arene to the dinuclear platinum complex trans-[{PtCl(NH3)2}2μ-dpzm]2+ and its implications for anticancer drug delivery. Journal of Inorganic Biochemistry, 103 (3). pp. 448-454. ISSN 0162-0134

Pisani, Michelle J. and Wheate, N.J. and Keene, F. Richard and Aldrich-Wright, J.R. and Collins, J. Grant (2009) Anionic PAMAM dendrimers as drug delivery vehicles for transition metal-based anticancer drugs. Journal of Inorganic Biochemistry, 103 (3). pp. 373-380. ISSN 0162-0134

Grant, M. and Wheate, Nial J. and Aldrich-Wright, Janice R. (2009) Diffusion coefficient of cucurbit[n]urils (n = 6 or 7) at different concentrations, temperatures and pH. Journal of Chemical and Engineering Data, 54 (2). pp. 323-326. ISSN 0021-9568

Krause-Heuer, A.M. and Wheate, N.J. and Price, William S. and Aldrich-Wright, Janice R. (2009) Diffusion-based studies on the self-stacking and nanorod formation of platinum(II) intercalators. Chemical Communications (London). pp. 1210-1212. ISSN 0009-241X

Kirkpatrick, G.J. and Sutcliffe, O.B. and Flint, D.J. and Wheate, N.J. (2009) PAMAM dendrimers as drug delivery vehicles for platinum anticancer drugs. In: Gordon Research Conference: Metals in Medicine, 2009-06-28 - 2009-07-02.

Krause-Heuer, A.M. and Grunert, R. and Kuhne, S. and Maruszak, M. and Wheate, N.J. and Le Pevelen, D. and Boag, L.R. and Fisher, D.M. (2009) Studies into the mechanism of action of platinum(II) complexes with potent cytotoxicity in human cancer cells. Journal of Medicinal Chemistry, 52 (17). pp. 5474-5484. ISSN 0022-2623

2008

Kemp, S. and Wheate, N.J. and Pisani, Michelle J. and Aldrich-Wright, J.R. (2008) Degradation of bidentate-coordinated platinum(II)-based DNA intercalators by reduced l-glutathione. Journal of Medicinal Chemistry, 51 (9). pp. 2787-2794. ISSN 0022-2623

Wheate, N.J. and Kumar, P.G.A. and Torres, A.M. and Aldrich-Wright, J.R. and Price, W.S. (2008) Examination of cucurbit[7]uril and its host-guest complexes by diffusion nuclear magnetic resonance. Journal of Physical Chemistry B, 112 (8). pp. 2311-2314. ISSN 1520-6106

Wheate, N.J. (2008) Improving platinum(II)-based anticancer drug delivery using cucurbit[n]urils. Journal of Inorganic Biochemistry, 102 (12). pp. 2060-2066. ISSN 0162-0134

Krause-Heuer, A.M. and Wheate, Nial J. and Tilby, Michael J. and Pearson, D. Graham and Ottley, Christoper J. and Aldrich-Wright, Janice R. (2008) Substituted β-cyclodextrins and calix[4]arene as encapsulatory vehicles for platinum(II)-based DNA intercalators. Inorganic Chemistry, 47 (15). pp. 6880-6888. ISSN 1520-510X

2007

Wheate, N.J. and Collins, J.G. and Kemp, S. and Aldrich-Wright, J.R. and Brodie, C.R. (2007) DNA intercalators in cancer therapy: organic and inorganic drugs and their spectroscopic tools of analysis. Mini-Reviews in Medicinal Chemistry, 7 (6). pp. 627-648. ISSN 1389-5575

Kemp, Sharon and Wheate, Nial J. and Wang, Shaoyu and Collins, J. Grant and Ralph, Stephen F. and Day, Anthony I. and Higgins, Vincent J. and Aldrich-Wright, Janice R. (2007) Encapsulation of platinum(II)-based DNA intercalators within cucurbit[6,7,8]urils. Journal of Biological Inorganic Chemistry, 12 (7). pp. 969-979. ISSN 0949-8257

Wheate, N.J. and Taleb, R.I. and Krause-Heuer, A.M. and Aldrich-Wright, J.R. and Higgins, V.J. and Wang, S. (2007) Novel platinum(II)-based anticancer complexes and molecular hosts as their drug delivery vehicles. Dalton Transactions, 2007. pp. 5055-5064. ISSN 1472-7773

Taleb, R.I. and Jaramillo, D. and Wheate, N.J. and Aldrich-Wright, J.R. (2007) Synthesis of DNA-sequence-selective hairpin polyamide platinum complexes. Chemistry - A European Journal, 13. pp. 3177-3186. ISSN 1521-3765

Yousouf, S.J. and Brodie, C.R. and Wheate, N.J. and Aldrich-Wright, J.R. (2007) Synthesis of a heterodinuclear ruthenium(II)-platinum(II) complex linked by l-cysteine methyl ester. Polyhedron, 26 (2). pp. 318-328. ISSN 0277-5387

Kemp, S. and Wheate, N.J. and Buck, D.P. and Nikac, M. and Collins, J.G. and Aldrich-Wright, J.R. (2007) The effect of ancillary ligand chirality and phenanthroline functional group substitution on the cytotoxicity of platinum(II)-based metallointercalators. Journal of Inorganic Biochemistry, 101 (7). pp. 1049-1058. ISSN 0162-0134

Kemp, Sharon and Wheate, Nial J. and Stootman, Frank H. and Aldrich-Wright, Janice R. (2007) The host-guest chemistry of proflavine with cucurbit[6,7,8]urils. Supramolecular Chemistry, 19 (7). pp. 475-484. ISSN 1061-0278

2006

Brodie, C.R. and Wheate, N.J. and Aldrich-Wright, J.R. (2006) (4,7-Dimethyl-1,10-phenanthroline)(ethylenediamine)platinum(II) dichloride tris(deuterium oxide) solvate. Acta Crystallographica Section E: Structure Reports, E62. m3137-m3139. ISSN 1600-5368

Jaramillo, D. and Wheate, N.J. and Ralph, S.F. and Howard, W.A. and Tor, Y. and Aldrich-Wright, J.R. (2006) Polyamide platinum anticancer complexes designed to target specific DNA sequences. Inorganic Chemistry, 45 (15). pp. 6004-6013. ISSN 1520-510X

2005

Wheate, Nial J. and Buck, Damian P. and Day, Anthony I. and Collins, J. Grant (2005) Cucurbit[n]uril binding of platinum anticancer complexes. Dalton Transactions (3). pp. 451-458. ISSN 1472-7773

2004

Wheate, N.J. and Day, A.I. and Blanch, R.J. and Arnold, A.P. and Cullinane, C. and Collins, J.G. (2004) Multi-nuclear platinum complexes encapsulated in cucurbit[n]uril as an approach to reduce toxicity in cancer treatment. Chemical Communications (London), 12. pp. 1424-1425. ISSN 0009-241X