Exosomes : fighting cancer with cancer

Alyamani, Hanin and Obeid, Mohammad A and Tate, Rothwelle J and Ferro, Valerie A (2018) Exosomes : fighting cancer with cancer. Therapeutic Delivery, 10 (1). ISSN 2041-5990 (https://doi.org/10.4155/tde-2018-0051)

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Exosomes are nanovesicles secreted by many cells, including cancer cells. Extensive research has been carried out to validate potential applications of exosomes and to evaluate their efficiency in a wide range of diseases, including cancer. The current knowledge on the origin, biogenesis and composition of exosomes is described. This review then focuses on the use of exosomes in cancer diagnostics and therapeutics.