Metabolomics and dereplication studies of endophytic metabolites from some Egyptian medicinal plants in the search potential antimicrobial drugs
Tawfike, Ahmed Fares and Edrada-Ebel, Ruangelie and Tate, Roth and Diederich, Marc and Schumacher, Marc and Sawadogo, Richard and Clements, Carol and Young, Louise (2014) Metabolomics and dereplication studies of endophytic metabolites from some Egyptian medicinal plants in the search potential antimicrobial drugs. In: Metabolomics 2014, 2014-06-23 - 2014-06-26, Daiichi Hotel Tsuruoka and Marica/Washington Hotel.
Full text not available in this repository.Request a copy from the Strathclyde authorAbstract
This study involved bioassay guided chromatographic isolation of three new natural compounds with 40 known bio-active metabolites from three endophytic fungi from different Egyptian medicinal plants. Identification of the strain has been achieved through molecular biological methods. Metabolomic profiling, using 2D-NMR and HR-ESIFTMS were done at different stages of the growth phase for both solid and liquid culture media. Dereplication studies were accomplished by utilizing the Mzmine software with the AntiBase database. The chemometric algorithms using SIMCA-P+ software were used to compare the active and inactive extracts and/or fractions in order to early predict the bioactive metabolites
Creators(s): |
Tawfike, Ahmed Fares ![]() | Item type: | Conference or Workshop Item(Poster) |
---|---|
ID code: | 56999 |
Keywords: | bioactive metabolites, Egyptian medicinal plants, anti cancer drugs, Pharmacy and materia medica, Pharmacology, Toxicology and Pharmaceutics(all) |
Subjects: | Medicine > Pharmacy and materia medica |
Department: | Faculty of Science > Strathclyde Institute of Pharmacy and Biomedical Sciences |
Depositing user: | Pure Administrator |
Date deposited: | 20 Jul 2016 13:10 |
Last modified: | 19 Feb 2021 03:08 |
Related URLs: | |
URI: | https://strathprints.strath.ac.uk/id/eprint/56999 |
Export data: |