Browse by Journal or other publication

2021

Ali, Eslam M.H and Abdel-Maksoud, Mohammed S. and Hassan, Rasha Mohamed and Mersal, Karim I. and Ammar, Usama M. and Se-In, Choi and He-Soo, Han and Kim, Hee-Kwon and Lee, Anna and Lee, Kyung-Tae and Oh, Chang-Hyun (2021) Design, synthesis and anti-inflammatory activity of imidazol-5-yl pyridine derivatives as p38α/MAPK14 inhibitor. Bioorganic and Medicinal Chemistry, 31. 115969. ISSN 0968-0896

2020

Shah, Rishi R. and Redmond, Joanna M. and Mihut, Andrei and Menon, Malini and Evans, John P. and Murphy, John A. and Bartholomew, Michelle A. and Coe, Diane M. (2020) Hi-JAK-ing the ubiquitin system : the design and physicochemical optimisation of JAK PROTACs. Bioorganic and Medicinal Chemistry, 28 (5). 115326. ISSN 0968-0896

2014

Miah, Afjal H. and Abas, Hossay and Begg, Malcolm and Marsh, Benjamin J. and O'Flynn, Daniel E. and Percy, Jonathan M. and Ford, Alison J. and Procopiou, Panayiotis A. and Richards, Steve A. (2014) Lead identification of benzimidazolone and azabenzimidazolone arylsulfonamides as CC-chemokine receptor 4 (CCR4) antagonists. Bioorganic and Medicinal Chemistry, 22 (15). pp. 4298-4311. ISSN 0968-0896

2013

Liu, Zheng and MacRitchie, Neil and Pyne, Susan and Pyne, Nigel J and Bittman, Robert (2013) Synthesis of (S)-FTY720 vinylphosphonate analogues and evaluation of their potential as sphingosine kinase 1 inhibitors and activators. Bioorganic and Medicinal Chemistry, 21 (9). pp. 2503-2510. ISSN 0968-0896

2012

Clark, Rachel L. and Clements, Carol J. and Barrett, Michael P. and Mackay, Simon P. and Rathnam, Rajendra P. and Owusu-Dapaah, George and Spencer, John and Huggan, Judith K. (2012) Identification and development of the 1,4-benzodiazepin-2-one and quinazoline-2,4-dione scaffolds as submicromolar inhibitors of HAT. Bioorganic and Medicinal Chemistry, 20 (20). pp. 6019-6033. ISSN 0968-0896

Petch, Donna and Anderson, Rosaleen J. and Cunningham, Anne and George, Suja E. and Hibbs, David E. and Liu, Ran and Mackay, Simon P. and Paul, Andrew and Small, David A. P. and Groundwater, Paul W. (2012) Design and synthesis of EGFR dimerization inhibitors and evaluation of their potential in the treatment of psoriasis. Bioorganic and Medicinal Chemistry, 20 (19). pp. 5901-5914. ISSN 0968-0896

2011

Ihmaid, S. and Al-Rawi, J. and Bradley, C. and Angove, M. J. and Robertson, M. N. and Clark, R. L. (2011) Synthesis, structural elucidation, DNA-PK inhibition, homology modelling and anti-platelet activity of morpholino-substituted-1,3-naphth-oxazines. Bioorganic and Medicinal Chemistry, 19 (13). pp. 3983-3994. ISSN 0968-0896

Spencer, John and Rathnam, Rajendra P. and Harvey, Alan L. and Clements, Carol J. and Clark, Rachel L. and Barrett, Michael P. and Wong, Pui Ee and Male, Louise and Coles, Simon J. and Mackay, Simon P. (2011) Synthesis and biological evaluation of 1,4-benzodiazepin-2-ones with antitrypanosomal activity. Bioorganic and Medicinal Chemistry, 19 (5). pp. 1802-1815.

Aly, Amal H and Debbab, Abdessamad and Clements, Carol and Edrada-Ebel, Ruangelie and Orlikova, Barbora and Diederich, Marc and Wray, Victor and Lin, Wenhan and Proksch, Peter (2011) NF kappa B inhibitors and antitrypanosomal metabolites from endophytic fungus Penicillium sp. isolated from Limonium tubiflorum. Bioorganic and Medicinal Chemistry, 19 (1). pp. 414-21.

2010

Hertiani, T. and Edrada-Ebel, RuAngelie and Ortlepp, S. and van Soest, R.W.M. and de Voogd, N.J. and Wray, Victor and Hentschel, Ute and Kozytska, Svitlana and Müller, Werner E.G. and Proksch, Peter (2010) From anti-fouling to biofilm inhibition : new cytotoxic secondary metabolites from two Indonesian Agelas sponges. Bioorganic and Medicinal Chemistry, 18 (3). 1297–1311.

Ibrahim, Sabrin R M and Min, Cho Cho and Teuscher, Franka and Ebel, Rainer and Kakoschke, Christel and Lin, Wenhan and Wray, Victor and Edrada-Ebel, RuAngelie and Proksch, Peter (2010) Callyaerins A-F and H, new cytotoxic cyclic peptides from the Indonesian marine sponge Callyspongia aerizusa. Bioorganic and Medicinal Chemistry, 18 (14). pp. 4947-56.

2009

Xu, J. and Kjer, J. and Sendker, J. and Wray, V. and Guan, H. and Edrada-Ebel, R.A. and Mueller, W.E.G. and Bayer, M. (2009) Cytosporones, coumarins, and an alkaloid from the endophytic fungus Pestalotiopsis sp. isolated from the Chinese mangrove plant Rhizophora mucronata. Bioorganic and Medicinal Chemistry, 17 (20). pp. 7362-7367.

2007

Clark, R.L. and Deane, F.M. and Anthony, N.G. and Johnston, B.F. and McCarthy, F.O. and Mackay, S.P. (2007) Exploring DNA topoisomerase I inhibition by the benzo[c]phenanthridines fagaronine and ethoxidine using steered molecular dynamics. Bioorganic and Medicinal Chemistry, 15 (14). pp. 4741-4752.