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Powering innovation in artificial intelligence with Open Access research...

Artificial intelligence (AI) and machine learning (ML) together represent a research frontier with a wide variety of discipline specific applications. At Strathclyde researchers in Computer & Information Sciences are exploring improved AI planning models to enable improved decision making by automous agents. Meanwhile, research conducted by the Aerospace Centre of Excellence is using AI and computational techniques to optimize the efficacy of certain astronautic applications. This includes 'global trajectory optimization' to aircraft and spacecraft design, from the planning and scheduling for autonomous vehicles to the synthesis of robust controllers for airplanes or satellites.

AI is also transforming the research agenda within Finance, where researchers are exploring the potential of AI and machine learning in evaluating banking risks and in new, emerging aspects of FinTech.

Explore some of this Open Access research from Computer & Information Sciences, Aerospace Centre of Excellence and Finance. Or explore all of Strathclyde's Open Access research...

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Number of items: 11.

Article

Miah, Afjal H. and Abas, Hossay and Begg, Malcolm and Marsh, Benjamin J. and O'Flynn, Daniel E. and Percy, Jonathan M. and Ford, Alison J. and Procopiou, Panayiotis A. and Richards, Steve A. (2014) Lead identification of benzimidazolone and azabenzimidazolone arylsulfonamides as CC-chemokine receptor 4 (CCR4) antagonists. Bioorganic and Medicinal Chemistry, 22 (15). pp. 4298-4311. ISSN 0968-0896

Liu, Zheng and MacRitchie, Neil and Pyne, Susan and Pyne, Nigel J and Bittman, Robert (2013) Synthesis of (S)-FTY720 vinylphosphonate analogues and evaluation of their potential as sphingosine kinase 1 inhibitors and activators. Bioorganic and Medicinal Chemistry, 21 (9). pp. 2503-2510. ISSN 0968-0896

Clark, Rachel L. and Clements, Carol J. and Barrett, Michael P. and Mackay, Simon P. and Rathnam, Rajendra P. and Owusu-Dapaah, George and Spencer, John and Huggan, Judith K. (2012) Identification and development of the 1,4-benzodiazepin-2-one and quinazoline-2,4-dione scaffolds as submicromolar inhibitors of HAT. Bioorganic and Medicinal Chemistry, 20 (20). pp. 6019-6033. ISSN 0968-0896

Petch, Donna and Anderson, Rosaleen J. and Cunningham, Anne and George, Suja E. and Hibbs, David E. and Liu, Ran and Mackay, Simon P. and Paul, Andrew and Small, David A. P. and Groundwater, Paul W. (2012) Design and synthesis of EGFR dimerization inhibitors and evaluation of their potential in the treatment of psoriasis. Bioorganic and Medicinal Chemistry, 20 (19). pp. 5901-5914. ISSN 0968-0896

Ihmaid, S. and Al-Rawi, J. and Bradley, C. and Angove, M. J. and Robertson, M. N. and Clark, R. L. (2011) Synthesis, structural elucidation, DNA-PK inhibition, homology modelling and anti-platelet activity of morpholino-substituted-1,3-naphth-oxazines. Bioorganic and Medicinal Chemistry, 19 (13). pp. 3983-3994. ISSN 0968-0896

Spencer, John and Rathnam, Rajendra P. and Harvey, Alan L. and Clements, Carol J. and Clark, Rachel L. and Barrett, Michael P. and Wong, Pui Ee and Male, Louise and Coles, Simon J. and Mackay, Simon P. (2011) Synthesis and biological evaluation of 1,4-benzodiazepin-2-ones with antitrypanosomal activity. Bioorganic and Medicinal Chemistry, 19 (5). pp. 1802-1815.

Aly, Amal H and Debbab, Abdessamad and Clements, Carol and Edrada-Ebel, Ruangelie and Orlikova, Barbora and Diederich, Marc and Wray, Victor and Lin, Wenhan and Proksch, Peter (2011) NF kappa B inhibitors and antitrypanosomal metabolites from endophytic fungus Penicillium sp. isolated from Limonium tubiflorum. Bioorganic and Medicinal Chemistry, 19 (1). pp. 414-21.

Hertiani, T. and Edrada-Ebel, RuAngelie and Ortlepp, S. and van Soest, R.W.M. and de Voogd, N.J. and Wray, Victor and Hentschel, Ute and Kozytska, Svitlana and Müller, Werner E.G. and Proksch, Peter (2010) From anti-fouling to biofilm inhibition : new cytotoxic secondary metabolites from two Indonesian Agelas sponges. Bioorganic and Medicinal Chemistry, 18 (3). 1297–1311.

Ibrahim, Sabrin R M and Min, Cho Cho and Teuscher, Franka and Ebel, Rainer and Kakoschke, Christel and Lin, Wenhan and Wray, Victor and Edrada-Ebel, RuAngelie and Proksch, Peter (2010) Callyaerins A-F and H, new cytotoxic cyclic peptides from the Indonesian marine sponge Callyspongia aerizusa. Bioorganic and Medicinal Chemistry, 18 (14). pp. 4947-56.

Xu, J. and Kjer, J. and Sendker, J. and Wray, V. and Guan, H. and Edrada-Ebel, R.A. and Mueller, W.E.G. and Bayer, M. (2009) Cytosporones, coumarins, and an alkaloid from the endophytic fungus Pestalotiopsis sp. isolated from the Chinese mangrove plant Rhizophora mucronata. Bioorganic and Medicinal Chemistry, 17 (20). pp. 7362-7367.

Clark, R.L. and Deane, F.M. and Anthony, N.G. and Johnston, B.F. and McCarthy, F.O. and Mackay, S.P. (2007) Exploring DNA topoisomerase I inhibition by the benzo[c]phenanthridines fagaronine and ethoxidine using steered molecular dynamics. Bioorganic and Medicinal Chemistry, 15 (14). pp. 4741-4752.

This list was generated on Mon Aug 3 12:51:00 2020 BST.