Lessons to be learnt from Leishmania studies
Shaw, CD and Carter, KC (2014) Lessons to be learnt from Leishmania studies. Nanomedicine, 9 (10). pp. 1531-1544. ISSN 1743-5889 (https://doi.org/10.2217/nnm.14.66)
Preview |
Text.
Filename: Shaw_Carter_Nanomedicine_2014_Drug_delivery_lessons_to_be_learnt_from_Leishmania.pdf
Accepted Author Manuscript Download (670kB)| Preview |
Abstract
Leishmaniasis is a disease caused by infection with the protozoan parasite Leishmania, which is responsible for three main types of disease: cutaneous leishmaniasis, visceral leishmaniasis and mucocutaneous leishmaniasis based to the site of infection for the particular species. This presents a major challenge to successful drug treatment, as a drug must not only reach antileishmanial concentrations in infected macrophages, the parasites' host cell, but also reach infected cells in locations specific to the type of disease. In this paper we discuss how studies using Leishmania have contributed to our knowledge on how drug delivery systems can be used to improve drug efficacy and delivery.
-
-
Item type: Article ID code: 56734 Dates: DateEvent1 July 2014Published17 June 2014AcceptedSubjects: Medicine > Pharmacy and materia medica Department: Faculty of Engineering > Design, Manufacture and Engineering Management
Faculty of Science > Strathclyde Institute of Pharmacy and Biomedical SciencesDepositing user: Pure Administrator Date deposited: 23 Jun 2016 15:41 Last modified: 19 Sep 2024 00:35 Related URLs: URI: https://strathprints.strath.ac.uk/id/eprint/56734