New avenues for drug delivery in Leishmania: using treatment of visceral leishmaniasis with amphotericin B as an exemplar.

Carter, Katharine and Mullen, Alexander; (2016) New avenues for drug delivery in Leishmania: using treatment of visceral leishmaniasis with amphotericin B as an exemplar. In: Drug Discovery in Leishmaniasis. Royal Society of Chemistry. (In Press)

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Abstract

In this review the benefits of using a drug delivery system (DDS) to improve therapeutic outcome will be discussed using treatment of visceral leishmaniasis with amphotericin B (AMB), a poorly water soluble drug, as an exemplar. Progress in producing AMB formulations that can be given by intravenous, oral and pulmonary routes of administration is discussed.

ORCID iDs

Carter, Katharine and Mullen, Alexander ORCID logoORCID: https://orcid.org/0000-0001-7475-5543;