Picture of DNA strand

Pioneering chemical biology & medicinal chemistry through Open Access research...

Strathprints makes available scholarly Open Access content by researchers in the Department of Pure & Applied Chemistry, based within the Faculty of Science.

Research here spans a wide range of topics from analytical chemistry to materials science, and from biological chemistry to theoretical chemistry. The specific work in chemical biology and medicinal chemistry, as an example, encompasses pioneering techniques in synthesis, bioinformatics, nucleic acid chemistry, amino acid chemistry, heterocyclic chemistry, biophysical chemistry and NMR spectroscopy.

Explore the Open Access research of the Department of Pure & Applied Chemistry. Or explore all of Strathclyde's Open Access research...

The effect of cell ingrowth on the mechanical behaviour of anchored collagen gels

Busby, Grahame and Riches, Philip and Grant, Mary and MacKay, Simon (2013) The effect of cell ingrowth on the mechanical behaviour of anchored collagen gels. International Journal of Artificial Organs, 36 (8). p. 567. ISSN 0391-3988

Full text not available in this repository.Request a copy from the Strathclyde author

Abstract

Collagen gels are often used in studies of cell-matrix interactions and as scaffolds for tissue engineering. However, the effect of cell proliferation on their bulk mechanical properties is still poorly understood. We recently published a method for extracting meaningful mechanical properties from collagen gels of > 99.5% water, using confined compression and biphasic theory (J Biomech 46 (2013) 837). In the present study we used this technique to investigate the effects of cell ingrowth on the transient mechanical behaviour of highly hydrated collagen gels.