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Open Access research which pushes advances in bionanotechnology

Strathprints makes available scholarly Open Access content by researchers in the Strathclyde Institute of Pharmacy & Biomedical Sciences (SIPBS) , based within the Faculty of Science.

SIPBS is a major research centre in Scotland focusing on 'new medicines', 'better medicines' and 'better use of medicines'. This includes the exploration of nanoparticles and nanomedicines within the wider research agenda of bionanotechnology, in which the tools of nanotechnology are applied to solve biological problems. At SIPBS multidisciplinary approaches are also pursued to improve bioscience understanding of novel therapeutic targets with the aim of developing therapeutic interventions and the investigation, development and manufacture of drug substances and products.

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The toxicity of orthopaedic biomaterials chromium and nickel in rat hepatocytes

Gunaratnam, M. and Grant, M.H. (2002) The toxicity of orthopaedic biomaterials chromium and nickel in rat hepatocytes. In: Transactions of the 28th Annual Meeting of the Society for Biomaterials. Society for Biomaterials. ISBN 8032087028

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Abstract

The toxicity of nickel, chromium (III) and (VI), vanadium and aluminium was compared in an immortalized neonatal rat osteoblast cell line using the MTT assay and a novel index of cytoxicity, alkaline phosphatase (ALP) activity.