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2024

Mark, David R. and Tucker, Nicholas P. and Herron, Paul R. (2024) Chromosome architecture as a determinant for biosynthetic diversity in micromonospora. Microbial Genomics, 10 (11). 001313. ISSN 2057-5858

2022

McSorley, James C. and MacFadyen, Alison C. and Kerr, Leena and Tucker, Nicholas Peter (2022) Host lysolipid differentially modulates virulence factor expression and antimicrobial susceptibility in. Microbiology, 168 (7). ISSN 1465-2080

2021

Sydney, Natashia and Swain, Martin T. and So, Jeffery M.T. and Hoiczyk, Egbert and Tucker, Nicholas P. and Whitworth, David E. (2021) The genetics of prey susceptibility to myxobacterial predation : a review, including an investigation into pseudomonas aeruginosa mutations affecting predation by Myxococcus xanthus. Microbial Physiology, 31 (2). pp. 57-66. ISSN 2673-1673

Moore, Matthew P. and Lamont, Iain L. and Williams, David and Paterson, Steve and Kukavica-Ibrulj, Irena and Tucker, Nicholas P. and Kenna, Dervla T.D. and Turton, Jane F. and Jeukens, Julie and Freschi, Luca and Wee, Brian A. and Loman, Nicholas J. and Holden, Stephen and Manzoor, Susan and Hawkey, Peter and Southern, Kevin W. and Walshaw, Martin J. and Levesque, Roger C. and Fothergill, Joanne L. and Winstanley, Craig (2021) Transmission, adaptation and geographical spread of the Pseudomonas aeruginosa Liverpool epidemic strain. Microbial Genomics, 7 (3). 000511. ISSN 2057-5858

Efthimiou, Georgios and Tucker, Nicholas P. (2021) Microbes Against Humanity, a workshop game for horrible students : using a creative card game in higher education microbiology teaching. Access Microbiology, 3 (2). ISSN 2516-8290

2020

O'Boyle, Nicky and Connolly, James P. R. and Tucker, Nicholas P. and Roe, Andrew J. (2020) Genomic plasticity of pathogenic Escherichia coli mediates D-serine tolerance via multiple adaptive mechanisms. Proceedings of the National Academy of Sciences of the United States of America, 117 (36). pp. 22484-22493. ISSN 1091-6490

Schniete, Jana K. and Reumerman, Richard and Kerr, Leena and Tucker, Nicholas P. and Hunter, Iain S. and Herron, Paul R. and Hoskisson, Paul A. (2020) Differential transcription of expanded gene families in central carbon metabolism of Streptomyces coelicolor A3(2). Access Microbiology. ISSN 2516-8290

2019

Lemonidis, Kimon and Salih, Talal S. and Dancer, Stephanie J. and Hunter, Iain S. and Tucker, Nicholas P. (2019) Emergence of an Australian-like pstS-null vancomycin resistant Enterococcus faecium clone in Scotland. PLoS ONE, 14 (6). e0218185. ISSN 1932-6203

2018

Ward, A.C. and Hannah, A.J. and Kendrick, S.L. and Tucker, N.P. and MacGregor, G. and Connolly, P. (2018) Identification and characterisation of Staphylococcus aureus on low cost screen printed carbon electrodes using impedance spectroscopy. Biosensors and Bioelectronics, 110. pp. 65-70. ISSN 0956-5663

Freschi, Luca and Bertelli, Claire and Jeukens, Julie and Moore, Matthew P. and Kukavica-Ibrulj, Irena and Emond-Rheault, Jean-Guillaume and Hamel, Jérémie and Fothergill, Joanne L and Tucker, Nicholas P. and McClean, Siobhán and Klockgether, Jens and de Soyza, Anthony and Brinkman, Fiona S.L. and Levesque, Roger C. and Winstanley, Craig (2018) Genomic characterisation of an international Pseudomonas aeruginosa reference panel indicates that the two major groups draw upon distinct mobile gene pools. FEMS Microbiology Letters. ISSN 0378-1097

Beaton, Ainsley and Lood, Cédric and Cunningham-Oakes, Edward and MacFadyen, Alison and Mullins, Alex J and Bestawy, Walid El and Botelho, João and Chevalier, Sylvie and Coleman, Shannon and Dalzell, Chloe and Dolan, Stephen K and Faccenda, Alberto and Ghequire, Maarten G K and Higgins, Steven and Kutschera, Alexander and Murray, Jordan and Redway, Martha and Salih, Talal and da Silva, Ana C and Smith, Brian A and Smits, Nathan and Thomson, Ryan and Woodcock, Stuart and Welch, Martin and Cornelis, Pierre and Lavigne, Rob and van Noort, Vera and Tucker, Nicholas P (2018) Community-led comparative genomic and phenotypic analysis of the aquaculture pathogen Pseudomonas baetica a390T sequenced by Ion semiconductor and Nanopore technologies. FEMS Microbiology Letters, 365 (9). fny069. ISSN 0378-1097

2017

Suckling, Colin J. and Khalaf, Abedawn and Scott, Fraser J. and Tucker, Nicholas and Niemenen, Leena and Lemonidis, Kimon and Hunter, Iain S. (2017) Why antibacterial minor groove binders are a good thing. In: 3rd International Electronic Conference on Medicinal Chemistry, 2017-11-01 - 2017-11-30.

Jeukens, Julie and Freschi, Luca and Kukavica-Ibrulj, Irena and Emond-Rheault, Jean-Guillaume and Tucker, Nicholas P and Levesque, Roger C (2017) Genomics of antibiotic-resistance prediction in Pseudomonas aeruginosa. Annals of the New York Academy of Sciences. ISSN 0077-8923

Adnan, Hazniza and Seidel, Veronique and Tucker, Nicholas P. (2017) Natural antibiofilm agents and the need for antibiofilm drug leads. Educatum Journal of Science, Mathematics and Technology, 4 (1). pp. 1-8. ISSN 2462-2451

2016

McCaughey, Laura C. and Josts, Inokentijs and Grinter, Rhys and White, Paul and Byron, Olwyn and Tucker, Nicholas P. and Matthews, Jacqueline M. and Kleanthous, Colin and Whitchurch, Cynthia B. and Walker, Daniel (2016) Discovery, characterisation and in vivo activity of pyocin SD2, a protein antibiotic from Pseudomonas aeruginosa. Biochemical Journal, 473 (15). pp. 2345-2358. ISSN 0264-6021

Lemieux, Andrée-Ann and Jeukens, Julie and Kukavica-Ibrulj, Irena and Fothergill, Joanne L. and Boyle, Brian and Laroche, Jérôme and Tucker, Nicholas P. and Winstanley, Craig and Levesque, Roger C. (2016) Genes required for free phage production are essential for pseudomonas aeruginosa chronic lung infections. Journal of Infectious Diseases, 213 (3). pp. 395-402. ISSN 0022-1899

2015

Freschi, Luca and Jeukens, Julie and Kukavica-Ibrulj, Irena and Boyle, Brian and Dupont, Marie-Josée and Laroche, Jérôme and Larose, Stéphane and Maaroufi, Halim and Fothergill, Joanne L. and Moores, Matthew and Winsor, Geoffrey L. and Aaron, Shawn D. and Barbeau, Jean and Bell, Scott C. and Burns, Jane L. and Camara, Miguel and Cantin, André and Charette, Steve J. and Dewar, Ken and Déziel, Éric and Grimwood, Keith and Hancock, Robert E. W. and Harrison, Joe J. and Heeb, Stephan and Jelsbak, Lars and Jia, Baofeng and Kenna, Dervla T. and Kidd, Timothy J. and Klockgether, Jens and Lam, Joseph S. and Lamont, Iain L. and Lewenza, Shawn and Loman, Nick and Malouin, François and Manos, Jim and McArthur, Andrew G. and McKeown, Josie and Milot, Julie and Naghra, Hardeep and Nguyen, Dao and Pereira, Sheldon K. and Perron, Gabriel G. and Pirnay, Jean-Paul and Rainey, Paul B. and Rousseau, Simon and Santos, Pedro M. and Stephenson, Anne and Taylor, Véronique and Turton, Jane F. and Waglechner, Nicholas and Williams, Paul and Thrane, Sandra W. and Wright, Gerard D. and Brinkman, Fiona S. L. and Tucker, Nicholas P. and Tümmler, Burkhard and Winstanley, Craig and Levesque, Roger C. (2015) Clinical utilization of genomics data produced by the international Pseudomonas aeruginosa consortium. Frontiers in Microbiology, 6. 1036. ISSN 1664-302X

Johns, Benjamin E. and Purdy, Kevin J. and Tucker, Nicholas P. and Maddocks, Sarah E. (2015) Phenotypic and genotypic characteristics of small colony variants and their role in chronic infection. Microbiology Insights, 8. pp. 15-23. ISSN 1178-6361

2014

Sangal, Vartul and Nieminen, Leena and Tucker, Nicholas P. and Hoskisson, Paul A.; Goodfellow, Michael and Sutcliffe, Iain and Chun, Jongsik, eds. (2014) Revolutionizing prokaryotic systematics through next-generation sequencing. In: New Approaches to Prokaryotic Systematics. Methods in Microbiology . Elsevier, pp. 75-101. ISBN 978-0-12-800176-9

Ward, Andrew C. and Tucker, Nicholas P. and Connolly, Patricia (2014) Development of a diagnostic device to detect different pseudomonas aeruginosa phenotypes in medically relevant contexts. In: Engineering in Medicine and Biology Society (EMBC), 2014 36th Annual International Conference of the IEEE, 2014-08-26 - 2014-08-30, IL.

Nieminen, Leena Kaija Linnea and Hunter, Iain and Suckling, Colin and Tucker, Nicholas (2014) The differing biological fates of DNA minor groove-binding (MGB) antibiotics in Gram-negative and Gram-positive bacteria. In: International Congresses of the International Union of Microbiological Societies (IUMS), 2014-07-27 - 2014-08-01, Palais des Congres de Montreal. (Unpublished)

Sangal, Vartul and Nieminen, Leena and Weinhardt, Barbara and Raeside, Jane and Tucker, Nicholas P. and Florea, Catalina Diana and Pollock, Kevin G. and Hoskisson, Paul A. (2014) Diphtheria-like disease caused by toxigenic corynebacterium ulcerans strain. Emerging Infectious Diseases, 20 (7). pp. 1257-1258. ISSN 1080-6040

Stewart, Lewis and Ford, Amy and Sangal, Vartul and Jeukens, Julie and Boyle, Brian and Kukavica-Ibrulj, Iréna and Caim, Shabhonam and Crossman, Lisa and Hoskisson, Paul A and Levesque, Roger and Tucker, Nicholas P (2014) Draft genomes of 12 host-adapted and environmental isolates of Pseudomonas aeruginosa and their positions in the core genome phylogeny. Pathogens and disease, 71.

Ward, Andrew C and Connolly, Patricia and Tucker, Nicholas P (2014) Pseudomonas aeruginosa can be detected in a polymicrobial competition model using impedance spectroscopy with a novel biosensor. PLOS One, 9 (3). e91732. ISSN 1932-6203

McCaughey, Laura C and Grinter, Rhys and Josts, Inokentijs and Roszak, Aleksander W and Waløen, Kai I and Cogdell, Richard J and Milner, Joel and Evans, Tom and Kelly, Sharon and Tucker, Nicholas P and Byron, Olwyn and Smith, Brian and Walker, Daniel (2014) Lectin-like bacteriocins from pseudomonas spp. utilise D-rhamnose containing lipopolysaccharide as a cellular receptor. PLOS Pathogens, 10 (2). e1003898. ISSN 1553-7366

Jeukens, Julie and Boyle, Brian and Kukavica-Ibrulj, Irena and Ouellet, Myriam M and Aaron, Shawn D and Charette, Steve J and Fothergill, Joanne L and Tucker, Nicholas P and Winstanley, Craig and Levesque, Roger C (2014) Comparative genomics of isolates of a pseudomonas aeruginosa epidemic strain associated with chronic lung infections of cystic fibrosis patients. PLOS One, 9 (2). e87611. ISSN 1932-6203

Jeukens, Julie and Boyle, Brian and Tucker, Nicholas P and Levesque, Roger C; Filloux, Alain and Ramos, Juan-Luis, eds. (2014) Strategy for genome sequencing analysis and assembly for comparative genomics of pseudomonas genomes. In: Pseudomonas Methods and Protocols. Methods in Molecular Biology . Springer, New York, pp. 565-577. ISBN 9781493904730

Mackenzie, Ashleigh and Stewart, Lewis and Hoskisson, Paul A and Tucker, Nicholas P; Filloux, Alain and Ramos, Juan-Luis, eds. (2014) Transcriptional analysis of pseudomonas aeruginosa Infected caenorhabditis elegans. In: Pseudomonas Methods and Protocols. Methods in Molecular Biology . Springer, New York, pp. 607-612. ISBN 9781493904723

2013

Candelaresi, Marco and Gumiero, Andrea and Adamczyk, Katrin and Robb, Kirsty and Bellota-Antón, César and Sangal, Vartul and Munnoch, John and Greetham, Gregory M and Towrie, Michael and Hoskisson, Paul A and Parker, Anthony W and Tucker, Nicholas P and Walsh, Martin A and Hunt, Neil T (2013) A structural and dynamic investigation of the inhibition of catalase by nitric oxide. Organic and Biomolecular Chemistry, 11 (44). pp. 7778-7788. ISSN 1477-0520

Reumerman, Richard A and Tucker, Nicholas P and Herron, Paul R and Hoskisson, Paul A and Sangal, Vartul (2013) Tool for rapid annotation of microbial SNPs (TRAMS) : a simple program for rapid annotation of genomic variation in prokaryotes. Antonie van Leeuwenhoek: International Journal of General and Molecular Microbiology, 104 (3). pp. 431-434. ISSN 0003-6072

2012

Sangal, Vartul and Tucker, Nicholas P and Burkovski, Andreas and Hoskisson, Paul A (2012) Draft genome sequence of Corynebacterium diphtheriae biovar intermedius NCTC 5011. Journal of Bacteriology, 194 (17). 4738. ISSN 1098-5530

Kirby, Ralph and Sangal, Vartul and Tucker, Nicholas and Zakrzewska-Czerwinska, Jolanta and Wierzbicka, K and Herron, Paul and Chu, C-J and Chandra, G. and Fahal, Ahmed and Goodfellow, Michael and Hoskisson, Paul (2012) Draft genome sequence of the human pathogen streptomyces somaliensis, a significant cause of actinomycetoma. Journal of Bacteriology, 194 (13). pp. 3544-3545. ISSN 1098-5530

Adamczyk, Katrin and Candelaresi, Marco and Robb, Kirsty and Gumiero, Andrea and Walsh, Martin A. and Parker, Anthony W. and Hoskisson, Paul A. and Tucker, Nicholas P. and Hunt, Neil T. (2012) Measuring protein dynamics with ultrafast two-dimensional infrared spectroscopy. Measurement Science and Technology, 23 (6). 062001. ISSN 0957-0233

Sangal, Vartul and Tucker, Nicholas P and Burkovski, Andreas and Hoskisson, Paul A (2012) The draft genome sequence of Corynebacterium diphtheriae bv. mitis NCTC 3529 reveals significant diversity between the primary disease-causing biovars. Journal of Bacteriology, 194 (12). p. 3269. ISSN 1098-5530

Sangal, Vartul and Tucker, Nicholas and Burkovski, Andreas and Hoskisson, Paul (2012) Draft genome of Corynebacterium diphtheria biovar intermedius NCTC 5011. Journal of Bacteriology. ISSN 1098-5530 (In Press)

Sangal, Vartul and Tucker, Nicholas and Burkovski, Andreas and Hoskisson, Paul (2012) The draft genome sequence of Corynebacterium diphtheriae mitis NCTC 3529 reveals significant diversity between the primary disease causing biovars. Journal of Bacteriology. ISSN 1098-5530 (In Press)

Adamczyk, Katrin and Candelaresi, Marco and Kania, Rafal and Robb, Kirsty and Bellota-Anton, Cesar and Greetham, Gregory M. and Pollard, Mark R. and Towrie, Michael and Parker, Anthony W. and Hoskisson, Paul A. and Tucker, Nicholas P. and Hunt, Neil T. (2012) The effect of point mutation on the equilibrium structural fluctuations of ferric Myoglobin. Physical Chemistry Chemical Physics, 14 (20). pp. 7411-7419. ISSN 1463-9084

2011

Hunt, Neil T. and Greetham, Gregory M. and Towrie, Michael and Parker, Anthony W. and Tucker, Nicholas P. (2011) Relationship between protein structural fluctuations and rebinding dynamics in ferric haem nitrosyls. Biochemical Journal, 433. pp. 459-468. ISSN 0264-6021

Bush, Matthew and Ghosh, Tamaswati and Tucker, Nicholas and Zhang, Xiaodong and Dixon, Ray (2011) Transcriptional regulation by the dedicated nitric oxide sensor, NorR: a route towards NO detoxification. Biochemical Society Transactions, 39 (1). pp. 289-293.

Bellota-Anton, Cesar and Munnoch, John and Robb, Kirsty and Adamczyk, Katrin and Candelaresi, Marco and Parker, Anthony W. and Dixon, Ray and Hutchings, Matthew I. and Hunt, Neil and Tucker, Nicholas (2011) Spectroscopic analysis of protein Fe-NO complexes. Biochemical Society Transactions, 39. 1293 -1298. ISSN 0300-5127

2010

Bush, Matthew and Ghosh, Tamaswati and Tucker, Nicholas and Zhang, Xiaodong and Dixon, Ray (2010) Nitric oxide-responsive interdomain regulation targets the σ54-interaction surface in the enhancer binding protein NorR. Molecular Microbiology, 77 (5). pp. 1278-1288.

Tucker, Nick and Ghosh, T. and Bush, M. and Zhang, X. and Dixon, Ray (2010) Essential roles of three enhancer sites in sigma-54-dependent transcription by the nitric oxide sensing regulatory protein NorR. Nucleic Acids Research, 38 (4). pp. 1182-1194. ISSN 1362-4962

2009

Tucker, N.P. and Le Brun, N.E. and Dixon, R. and Hutchings, M.I. (2009) There's NO stopping NsrR, a global regulator of the bacterial NO stress response. Trends in Microbiology, 18 (4). pp. 149-159. ISSN 0966-842X

2008

Tucker, Nick and Hicks, Matthew G. and Clarke, Thomas A. and Crack, Jason C. and Chandra, Govinda and Le Brun, Nick E. and Dixon, Ray and Hutchings, Matthew I. (2008) The transcriptional repressor protein NsrR senses nitric oxide directly via a [2Fe-2S] cluster. PLoS One, 3 (11). e3623. ISSN 1932-6203

Tucker, Nick and D'Autréaux, Benoît and Yousafzai, Faridoon K. and Fairhurst, Shirley A. and Spiro, Stephen and Dixon, Ray (2008) Analysis of the nitric oxide-sensing non-heme iron center in the NorR regulatory protein. Journal of Biological Chemistry, 283 (2). pp. 908-918. ISSN 1083-351X

D'Autréaux, Benoît and Tucker, Nick and Spiro, Stephen and Dixon, Ray (2008) Characterization of the nitric oxide-reactive transcriptional activator NorR. Methods in Enzmology, 437. pp. 235-251. ISSN 0076-6879

2006

Tucker, N P and D'autréaux, B and Spiro, S and Dixon, R (2006) Mechanism of transcriptional regulation by the Escherichia coli nitric oxide sensor NorR. Biochemical Society Transactions, 34 (1). pp. 191-194. ISSN 0300-5127

2005

D'Autréaux, Benoît and Tucker, Nicholas P and Dixon, Ray and Spiro, Stephen (2005) A non-haem iron centre in the transcription factor NorR senses nitric oxide. Nature, 437 (7059). pp. 769-772.

Tucker, N and D'autréaux, B and Spiro, S and Dixon, R (2005) DNA binding properties of the Escherichia coli nitric oxide sensor NorR : towards an understanding of the regulation of flavorubredoxin expression. Biochemical Society Transactions, 33 (Part 1). pp. 181-183. ISSN 0300-5127

2004

Tucker, Nicholas P and D'Autréaux, Benoît and Studholme, David J and Spiro, Stephen and Dixon, Ray (2004) DNA binding activity of the Escherichia coli nitric oxide sensor NorR suggests a conserved target sequence in diverse proteobacteria. Journal of Bacteriology, 186 (19). pp. 6656-6660. ISSN 1098-5530

2003

Waddington, Simon N and Buckley, Suzanne M K and Nivsarkar, Megha and Jezzard, Sarah and Schneider, Holm and Dahse, Thomas and Kemball-Cook, Geoff and Miah, Maznu and Tucker, Nick and Dallman, Margaret J and Themis, Mike and Coutelle, Charles (2003) In utero gene transfer of human factor IX to fetal mice can induce postnatal tolerance of the exogenous clotting factor. Blood, 101 (4). pp. 1359-1366. ISSN 0006-4971