Browse by Author or creator

2024

Li, Xiang and Cole, John and Vaughan, Diane and Xiao, Yinbo and Walker, Daniel and Wall, Daniel m. (2024) Stratifying macrophages based on their infectious burden identifies novel host targets for intervention during Crohn’s disease associated adherent-invasive Escherichia coli infection. Microbiology, 170 (6). 001470. ISSN 1465-2080

2023

Faqerah, Nojoud and Walker, Daniel and Gerasimidis, Konstantinos (2023) Review article : The complex interplay between diet and Escherichia coli in inflammatory bowel disease. Alimentary Pharmacology and Therapeutics, 58 (10). pp. 984-1004. ISSN 0269-2813

Premsuriya, Jiraphan and Mosbahi, Khedidja and Atanaskovic, Iva and Kleanthous, Colin and Walker, Daniel (2023) Outer membrane translocation of pyocins via the copper regulated TonB-dependent transporter CrtA. Biochemical Journal, 480 (14). pp. 1035-1049. ISSN 0264-6021

Li, Xiang and Ormsby, Michael J. and Fallata, Ghaith and Meikle, Lynsey M. and Walker, Daniel and Xu, Damo and Wall, Daniel M. (2023) PF-431396 hydrate inhibition of kinase phosphorylation during adherent-invasive Escherichia coli infection inhibits intra-macrophage replication and inflammatory cytokine release. Microbiology, 169 (6). 001337. ISSN 1465-2080

2021

Carpena, Nuria and Richards, Kerry and Gonzalez, Teresita D. J. Bello and Bravo-Blas, Alberto and Housden, Nicholas G. and Gerasimidis, Konstantinos and Milling, Simon W. F. and Douce, Gillian and Malik, Danish J. and Walker, Daniel (2021) Targeted delivery of narrow-spectrum protein antibiotics to the lower gastrointestinal tract in a murine model of escherichia coli colonization. Frontiers in Microbiology, 12. pp. 1-12. 670535. ISSN 1664-302X

Chai, Ray and Rooney, William M and Milner, Joel J and Walker, Daniel (2021) Challenges of using protein antibiotics for pathogen control. Pest Management Science, 77 (9). pp. 3836-3840. ISSN 1526-498X

Six, Anne and Mosbahi, Khedidja and Barge, Madhuri and Kleanthous, Colin and Evans, Thomas and Walker, Daniel (2021) Pyocin efficacy in a murine model of Pseudomonas aeruginosa sepsis. Journal of Antimicrobial Chemotherapy, 76 (9). 2317–2324. ISSN 0305-7453

2020

Wojnowska, Marta and Walker, Daniel (2020) FusB energizes import across the outer membrane through direct interaction with its ferredoxin substrate. mBio, 11 (5). pp. 1-11. ISSN 2150-7511

Rooney, William M. and Grinter, Rhys W. and Correia, Annapaula and Parkhill, Julian and Walker, Daniel C. and Milner, Joel J. (2020) Engineering bacteriocin‐mediated resistance against the plant pathogen Pseudomonas syringae. Plant Biotechnology Journal, 18 (5). pp. 1296-1306.

Behrens, Hannah M. and Lowe, Edward D. and Gault, Joseph and Housden, Nicholas G. and Kaminska, Renata and Weber, T. Moritz and Thompson, Catriona M. A. and Mislin, Gaëtan L. A. and Schalk, Isabelle J. and Walker, Daniel and Robinson, Carol V. and Kleanthous, Colin (2020) Pyocin S5 import into pseudomonas aeruginosa reveals a generic mode of bacteriocin transport. mBio, 11 (2). pp. 1-16. ISSN 2150-7511

2018

Mosbahi, Khedidja and Wojnowska, Marta and Albalat, Amaya and Walker, Daniel (2018) Bacterial iron acquisition mediated by outer membrane translocation and cleavage of a host protein. Proceedings of the National Academy of Sciences, 115 (26). pp. 6840-6845.

2017

Josts, I. and Stubenrauch, C.J. and Vadlamani, G. and Mosbahi, K. and Walker, D. and Lithgow, T. and Grinter, R. (2017) The structure of a conserved domain of TamB reveals a hydrophobic β taco fold. Structure, 25 (12). pp. 1898-1906. e5. ISSN 0969-2126

White, Paul and Joshi, Amar and Rassam, Patrice and Housden, Nicholas G. and Kaminska, Renata and Goult, Jonathan D. and Redfield, Christina and McCaughey, Laura C. and Walker, Daniel and Mohammed, Shabaz and Kleanthous, Colin (2017) Exploitation of an iron transporter for bacterial protein antibiotic import. Proceedings of the National Academy of Sciences, 114 (45). pp. 12051-12056. ISSN 1091-6490

2016

Grinter, Rhys and Josts, Inokentijs and Mosbahi, Khedidja and Roszak, Aleksander W. and Cogdell, Richard J. and Bonvin, Alexandre M.J.J. and Milner, Joel J. and Kelly, Sharon M. and Byron, Olwyn and Smith, Brian O. and Walker, Daniel (2016) Structure of the bacterial plant-ferredoxin receptor FusA. Nature Communications, 7. 13308. ISSN 2041-1723

Klein, Alexander and Wojdyla, Justyna Aleksandra and Joshi, Amar and Josts, Inokentijs and McCaughey, Laura C. and Housden, Nicholas G. and Kaminska, Renata and Byron, Olwyn and Walker, Daniel and Kleanthous, Colin (2016) Structural and biophysical analysis of nuclease protein antibiotics. Biochemical Journal, 476 (18). pp. 2799-2812. ISSN 0264-6021

McCaughey, Laura C. and Josts, Inokentijs and Grinter, Rhys and White, Paul and Byron, Olwyn and Tucker, Nicholas P. and Matthews, Jacqueline M. and Kleanthous, Colin and Whitchurch, Cynthia B. and Walker, Daniel (2016) Discovery, characterisation and in vivo activity of pyocin SD2, a protein antibiotic from Pseudomonas aeruginosa. Biochemical Journal, 473 (15). pp. 2345-2358. ISSN 0264-6021

McCaughey, Laura C. and Ritchie, Neil D. and Douce, Gillian R. and Evans, Thomas J. and Walker, Daniel (2016) Efficacy of species-specific protein antibiotics in a murine model of acute Pseudomonas aeruginosa lung infection. Scientific Reports, 6. 30201. ISSN 2045-2322

Ashraf, Khuram U. and Josts, Inokentijs and Mosbahi, Khedidja and Kelly, Sharon M. and Byron, Olwyn and Smith, Brian O. and Walker, Daniel (2016) The potassium binding protein Kbp is a cytoplasmic potassium sensor. Structure, 24 (5). pp. 741-749. ISSN 0969-2126

Connolly, James P. R. and Gabrielsen, Mads and Goldstone, Robert J. and Grinter, Rhys and Wang, Dai and Cogdell, Richard J. and Walker, Daniel and Smith, David G. E. and Roe, Andrew J. (2016) A highly conserved bacterial D-serine uptake system links host metabolism and virulence. PLOS Pathogens, 12 (1). e1005359. ISSN 1553-7366

2015

Joshi, Amar and Grinter, Rhys and Josts, Inokentijs and Chen, Sabrina and Wojdyla, Justyna A. and Lowe, Edward D. and Kaminska, Renata and Sharp, Connor and McCaughey, Laura and Roszak, Aleksander W. and Cogdell, Richard J. and Byron, Olwyn and Walker, Daniel and Kleanthous, Colin (2015) Structures of the ultra-high-affinity protein-protein complexes of pyocins S2 and AP41 and their cognate immunity proteins from Pseudomonas aeruginosa. Journal of Molecular Biology, 427 (17). pp. 2852-2866. ISSN 0022-2836

Fyfe, C. D. and Grinter, R. and Josts, I. and Mosbahi, K. and Roszak, A. W. and Cogdell, R. J. and Wall, D. M. and Burchmore, R. J. and Byron, O. and Walker, D. (2015) Structure of protease-cleaved Escherichia coli α-2-macroglobulin reveals a putative mechanism of conformational activation for protease entrapment. Structure, 71. pp. 1478-1486. ISSN 0969-2126

Papadakos, Grigorios and Sharma, Amit and Lancaster, Lorna E. and Bowen, Rebecca and Kaminska, Renata and Leech, Andrew P. and Walker, Daniel and Redfield, Christina and Kleanthous, Colin (2015) Consequences of inducing intrinsic disorder in a high-affinity protein-protein interaction. Journal of the American Chemical Society, 137 (16). 5252–5255. ISSN 1520-5126

2014

McCaughey, Laura C and Grinter, Rhys and Josts, Inokentijs and Roszak, Aleksander W and Waløen, Kai I and Cogdell, Richard J and Milner, Joel and Evans, Tom and Kelly, Sharon and Tucker, Nicholas P and Byron, Olwyn and Smith, Brian and Walker, Daniel (2014) Lectin-like bacteriocins from pseudomonas spp. utilise D-rhamnose containing lipopolysaccharide as a cellular receptor. PLOS Pathogens, 10 (2). e1003898. ISSN 1553-7366

2012

Grinter, Rhys and Milner, Joel and Walker, Daniel (2012) Ferredoxin containing bacteriocins suggest a novel mechanism of iron uptake in Pectobacterium spp. PLOS One, 7 (3). e33033. ISSN 1932-6203

2007

Walker, Daniel and Mosbahi, Khédidja and Vankemmelbeke, Mireille and James, Richard and Kleanthous, Colin (2007) The role of electrostatics in colicin nuclease domain translocation into bacterial cells. Journal of Biological Chemistry, 282 (43). pp. 31389-31397. ISSN 1083-351X