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Number of items: 47.

2018

Littleson, Mairi M. and Baker, Christopher M. and Dalencon, Anne J. and Frye, Elizabeth C. and Jamieson, Craig and Kennedy, Alan R. and Ling, Kenneth B. and McLachlan, Matthew M. and Montgomery, Mark G. and Russell, Claire J. and Watson, Allan J. B. (2018) Scalable total synthesis and comprehensive structure–activity relationship studies of the phytotoxin coronatine. Nature Communications. ISSN 2041-1723 (In Press)

Molloy, John J. and Seath, Ciaran P. and West, Matthew J. and McLaughlin, Calum and Fazakerley, Neal J. and Kennedy, Alan R. and Nelson, David J. and Watson, Allan J. B. (2018) Interrogating Pd(II) anion metathesis using a bifunctional chemical probe : a transmetalation switch. Journal of the American Chemical Society, 140 (1). pp. 126-130. ISSN 1520-5126

2017

McPherson, Christopher G. and Cooper, Alasdair K. and Bubliauskas, Andrius and Mulrainey, Paul and Jamieson, Craig and Watson, Allan J. B. (2017) A multicomponent route to functionalized amides and oxazolidinones. Organic Letters. ISSN 1523-7060

Campbell, Peter S. and Jamieson, Craig and Simpson, Iain and Watson, Allan J. B. (2017) Practical synthesis of pharmaceutically relevant molecules enriched in sp3 character. Chemical Communications (London). ISSN 0009-241X

Xu, Chao and Fyfe, James W.B. and Seath, Ciaran P. and Bennett, Steven H. and Watson, Allan J.B. (2017) A one-pot tandem chemoselective allylation/cross-coupling via temperature control of a multi-nucleophile/electrophile system. Chemical Communications (London), 53. pp. 9139-9142. ISSN 0009-241X

Fyfe, James W.B. and Watson, Allan J.B. (2017) Recent developments in organoboron chemistry - old dogs, new tricks. Chem, 3 (1). pp. 31-35. ISSN 2451-9294

Hatit, Marine Z. C. and Seath, Ciaran P. and Watson, Allan J. B. and Burley, Glenn A. (2017) A strategy for conditional orthogonal sequential CuAAC reactions using a protected aromatic ynamine. Journal of Organic Chemistry. ISSN 0022-3263

Vantourout, Julien C. and Miras, Haralampos N. and Isidro-Llobet, Albert and Sproules, Stephen and Watson, Allan J. B. (2017) Spectroscopic studies of the Chan-Lam amination : a mechanism-inspired solution to boronic ester reactivity. Journal of the American Chemical Society, 139 (13). 4769–4779. ISSN 1520-5126

McPherson, Christopher G. and Caldwell, Nicola and Jamieson, Craig and Simpson, Iain and Watson, Allan J. B. (2017) Amidation of unactivated ester derivatives mediated by trifluoroethanol. Organic and Biomolecular Chemistry. ISSN 1477-0520

Seath, Ciaran P. and Burley, Glenn A. and Watson, Allan J. B. (2017) Determining the origin of rate-independent chemoselectivity in CuAAC reactions : an alkyne-specific shift in rate-determining step. Angewandte Chemie International Edition, 56 (12). pp. 3314-3318. ISSN 1521-3773

Keune, Willem-Jan and Potjewyd, Frances and Heidebrecht, Tatjana and Salgado-Polo, Fernando and Macdonald, Simon J. F. and Chelvarajan, Lakshman and Abdel Latif, Ahmed and Soman, Sony and Morris, Andrew J. and Watson, Allan J. B. and Jamieson, Craig and Perrakis, Anastassis (2017) Rational design of autotaxin inhibitors by structural evolution of endogenous modulators. Journal of Medicinal Chemistry, 60 (5). pp. 2006-2017. ISSN 0022-2623

Miller, Lisa M. and Pritchard, John M. and Macdonald, Simon J. F. and Jamieson, Craig and Watson, Allan J. B. (2017) Emergence of small molecule non-RGD-mimetic inhibitors for RGD integrins. Journal of Medicinal Chemistry, 60 (8). ISSN 0022-2623

Miller, Lisa M. and Keune, Willem-Jan and Castagna, Diana and Young, Louise C. and Duffy, Emma L. and Potjewyd, Frances and Salgado-Polo, Fernando and Garcia, Paloma Engel and Semaan, Dima and Pritchard, John M. and Perrakis, Anastassis and Macdonald, Simon J. F. and Jamieson, Craig and Watson, Allan J. B. (2017) Structure-activity relationships of small molecule autotaxin inhibitors with a discrete binding mode. Journal of Medicinal Chemistry, 60 (2). pp. 722-748. ISSN 0022-2623

Fyfe, James W. B. and Fazakerley, Neal J. and Watson, Allan J. B. (2017) Chemoselective Suzuki-Miyaura cross-coupling via kinetic transmetallation. Angewandte Chemie International Edition, 56 (5). pp. 1249-1253. ISSN 1521-3773

2016

Molloy, John J. and Clohessy, Thomas Aidan and Irving, Craig and Anderson, Niall A. and Lloyd-Jones, Guy C. and Watson, Allan J. B. (2016) Chemoselective oxidation of aryl organoboron systems enabled by boronic acid-selective phase transfer. Chemical Science. ISSN 2041-6539

Wilson, Kirsty and Kennedy, Alan and Murray, Jane and Greatex, Ben and Jamieson, Craig and Watson, Allan (2016) Scope and limitations of a DMF bio-alternative within Sonogashira cross-coupling and Cacchi-type annulation. Beilstein Journal of Organic Chemistry, 12. pp. 2005-2011. ISSN 1860-5397

Littleson, Mairi M. and Russell, Claire J. and Frye, Elizabeth C. and Ling, Kenneth B. and Jamieson, Craig and Watson, Allan J. B. (2016) Synthetic approaches to coronafacic acid, coronamic acid, and coronatine. Synthesis, 48. ISSN 0039-7881

Seath, Ciaran Paul and Fyfe, James W. B. and Molloy, John J. and Watson, Allan J. B. (2016) Synthesis of oxindoles and benozfuranones via oxidation of 2-heterocyclic BMIDAs. Synthesis. ISSN 0039-7881

Seath, Ciaran P. and Wilson, Kirsty L. and Campbell, Angus and Mowat, Jenna M. and Watson, Allan J. B. (2016) Synthesis of 2-BMIDA 6,5-bicyclic heterocycles by Cu(I)/Pd(0)/Cu(II) cascade catalysis of 2-iodoaniline/phenols. Chemical Communications (56). pp. 8703-8706. ISSN 1359-7345

Vantourout, Julien C. and Law, Robert P. and Isidro-Llobet, Albert and Atkinson, Stephen J. and Watson, Allan J. B. (2016) Chan–Evans–Lam amination of boronic acid pinacol (BPin) esters : overcoming the aryl amine problem. Journal of Organic Chemistry. ISSN 0022-3263

Hatit, Marine Z. C. and Sadler, Joanna C. and McLean, Liam A. and Whitehurst, Benjamin C. and Seath, Ciaran P. and Humphreys, Luke D. and Young, Robert J. and Watson, Allan J. B. and Burley, Glenn A. (2016) Chemoselective sequential click ligations directed by enhanced reactivity of an aromatic ynamine. Organic Letters, 18 (7). pp. 1694-1697. ISSN 1523-7060

2015

Muir, Calum W. and Vantourout, Julien C. and Isidro-Llobet, Albert and Macdonald, Simon J. F. and Watson, Allan J. B. (2015) One-pot homologation of boronic acids : a platform for diversity-oriented synthesis. Organic Letters, 17 (24). 6030–6033. ISSN 1523-7060

Seath, Ciaran P. and Fyfe, James W. B. and Molloy, John J. and Watson, Allan J. B. (2015) Tandem chemoselective Suzuki-Miyaura cross-coupling enabled by nucleophile speciation control. Angewandte Chemie, 54 (34). pp. 9976-9979. ISSN 1521-3773

Fyfe, James W. B. and Valverde, Elena and Seath, Ciaran P. and Kennedy, Alan R. and Redmond, Joanna M. and Anderson, Niall A. and Watson, Allan J. B. (2015) Speciation control during Suzuki-Miyaura cross-coupling of haloaryl and haloalkenyl MIDA boronic esters. Chemistry - A European Journal, 21 (24). 8951–8964. ISSN 1521-3765

Castagna, Diana and Duffy, Emma L. and Semaan, Dima and Young, Louise C. and Pritchard, John M. and Macdonald, Simon J. F. and Budd, David C. and Jamieson, Craig and Watson, Allan J. B. (2015) Identification of a novel class of autotaxin inhibitors through cross-screening. MedChemComm, 2015 (6). pp. 1149-1155. ISSN 2040-2503

Fyfe, James W. B. and Watson, Allan J. B. (2015) Strategies towards chemoselective suzuki-miyaura cross-coupling. Synlett, 26 (9). pp. 1139-1144. ISSN 0936-5214

Eastman, Harry E. and Jamieson, Craig and Watson, Allan J. B. (2015) Development of solvent selection guides. Aldrichimica Acta, 48 (2). pp. 51-55.

Molloy, John J. and Law, Robert P. and Fyfe, James W.B. and Seath, Ciaran P. and Hirst, David J. and Watson, Allan J.B. (2015) A modular synthesis of functionalised phenols enabled by controlled boron speciation. Organic and Biomolecular Chemistry. ISSN 1477-0520

2014

Fyfe, James W. B. and Seath, Ciaran P. and Watson, Allan J. B. (2014) Chemoselective boronic ester synthesis via controlled speciation. Angewandte Chemie, 53 (45). 12077–12080. ISSN 1521-3773

Carswell, Emma L. and Kerr, William J and McArthur, Duncan and Pazicky, Marek and Watson, Allan (2014) Development of chiral heteroleptic magnesium amides; asymmetric deprotonations mediated by six-membered metallocyclic amidomagnesium naphtholates. Tetrahedron, 70 (40). pp. 7344-7349. ISSN 0040-4020

Caldwell, Nicola and Campbell, Peter S. and Jamieson, Craig and Potjewyd, Frances and Simpson, Iain and Watson, Allan J. B. (2014) Amidation of esters with amino alcohols using organobase catalysis. Journal of Organic Chemistry, 79 (19). pp. 9347-9354. ISSN 0022-3263

McGonagle, Fiona I. and Sneddon, Helen F. and Jamieson, Craig and Watson, Allan (2014) Molar efficiency : a useful metric to gauge relative reaction efficiency in discovery medicinal chemistry. ACS Sustainable Chemistry and Engineering, 2 (3). pp. 523-532. ISSN 2168-0485

2013

Caldwell, Nicola and Jamieson, Craig and Simpson, Iain and Watson, Allan J. B. (2013) Development of a sustainable catalytic ester amidation process. ACS Sustainable Chemistry and Engineering, 1 (10). pp. 1339-1344.

Muir, Calum William and Kennedy, Alan and Redmond, Joanna and Watson, Allan (2013) Synthesis of functionalised 4H-quinolizin-4-ones via tandem Horner–Wadsworth–Emmons olefination/cyclisation. Organic and Biomolecular Chemistry, 11 (20). pp. 3337-3340. ISSN 1477-0520

Rajasekharan Nair, Rajeev and Marckwordt, Annemarie and Lutta, Samuel and Schwalbe, Matthias and Biernat, Anne and Armstrong, David and Watson, Allan and Kennedy, Alan and Reglinski, John and Spicer, Mark (2013) Soft Scorpionate anions as platforms for novel heterocycles. Chemistry - A European Journal, 19 (40). 13561–13568. ISSN 1521-3765

2012

Anderson, Niall A and Fallon, Brendan J and Valverde, Elena and MacDonald, Simon J F and Pritchard, John M and Suckling, Colin and Watson, Allan (2012) Asymmetric rhodium-catalysed addition of arylboronic acids to acyclic unsaturated esters containing a basic γ-amino group. Synlett, 23 (19). pp. 2817-2821. ISSN 0936-5214

MacMillan, Donna Stephanie and Murray, Jane and Sneddon, Helen F. and Jamieson, Craig and Watson, Allan (2012) Replacement of dichloromethane within chromatographic purification : a guide to alternative solvents. Green Chemistry, 14 (11). pp. 3016-3019. ISSN 1463-9262

2011

Watson, Allan; List, B., ed. (2011) Iminium catalysis. In: Science of Synthesis. Science of Synthesis . Thieme, pp. 309-401.

Kerr, William and Middleditch, Michael and Watson, Allan (2011) New potentially chelating chiral magnesium amide bases for use in enantioselective deprotonation reactions. Synlett (2). pp. 177-180. ISSN 0936-5214

Bennie, Linsey Sarah and Kerr, William and Middleditch, Michael and Watson, Allan (2011) Towards energetically viable asymmetric deprotonations : selectivity at more elevated temperatures with C2-symmetric magnesium bisamides. Chemical Communications (London), 47 (8). pp. 2264-2266. ISSN 0009-241X

Watson, Allan and MacMillan, David; Evans, P.A., ed. (2011) alpha-Functionalization of carbonyl compounds. In: Science of Synthesis: Stereoselective Synthesis 3; Stereoselective Pericyclic Reactions Cross-coupling, and C-H and C-X Activation. Science of Synthesis . Thieme, Stuttgart, pp. 675-745.