Tandem chemoselective Suzuki-Miyaura cross-coupling enabled by nucleophile speciation control

Seath, Ciaran P. and Fyfe, James W. B. and Molloy, John J. and Watson, Allan J. B. (2015) Tandem chemoselective Suzuki-Miyaura cross-coupling enabled by nucleophile speciation control. Angewandte Chemie, 54 (34). pp. 9976-9979. ISSN 0044-8249

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    Abstract

    Control of boronic acid speciation is presented as a strategy to achieve nucleophile chemoselectivity in the Suzuki-Miyaura reaction. Combined with simultaneous control of oxidative addition and transmetallation, this enables chemoselective formation of two C-C bonds in a single operation, providing a method for the rapid preparation of highly functionalized carbogenic frameworks.

    ORCID iDs

    Seath, Ciaran P. ORCID logoORCID: https://orcid.org/0000-0002-6774-128X, Fyfe, James W. B. ORCID logoORCID: https://orcid.org/0000-0001-8501-9197, Molloy, John J. ORCID logoORCID: https://orcid.org/0000-0002-0538-7852 and Watson, Allan J. B.;
    • Item type:Article
      ID code:53425
      Dates:
      Date
      Event
      17 August 2015
      Published
      1 July 2015
      Published Online
      17 June 2015
      Accepted
      Notes:This is the peer reviewed version of the following article: Seath, C. P., Fyfe, J. W. B., Molloy, J. J., & Watson, A. J. B. (2015). Tandem chemoselective Suzuki-Miyaura cross-coupling enabled by nucleophile speciation control. Angewandte Chemie, which has been published in final form at http://www.dx.doi.org/10.1002/ange.201504297. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Self-Archiving
      Keywords:boron, chemoselectivity, cross-coupling, palladium, speciation, Chemistry, Chemistry(all)
      Subjects:Science > Chemistry
      Department:Faculty of Science > Pure and Applied Chemistry
      Depositing user: Pure Administrator
      Date deposited:18 Jun 2015 15:09
      Last modified:23 Sep 2021 05:07
      Related URLs:
      URI:https://strathprints.strath.ac.uk/id/eprint/53425
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