Tandem chemoselective Suzuki-Miyaura cross-coupling enabled by nucleophile speciation control

Seath, Ciaran P. and Fyfe, James W. B. and Molloy, John J. and Watson, Allan J. B. (2015) Tandem chemoselective Suzuki-Miyaura cross-coupling enabled by nucleophile speciation control. Angewandte Chemie, 54 (34). pp. 9976-9979. ISSN 0044-8249

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    Abstract

    Control of boronic acid speciation is presented as a strategy to achieve nucleophile chemoselectivity in the Suzuki-Miyaura reaction. Combined with simultaneous control of oxidative addition and transmetallation, this enables chemoselective formation of two C-C bonds in a single operation, providing a method for the rapid preparation of highly functionalized carbogenic frameworks.

    Creators(s): Seath, Ciaran P. ORCID logoORCID: https://orcid.org/0000-0002-6774-128X, Fyfe, James W. B. ORCID logoORCID: https://orcid.org/0000-0001-8501-9197, Molloy, John J. ORCID logoORCID: https://orcid.org/0000-0002-0538-7852 and Watson, Allan J. B.;
    Item type:Article
    ID code:53425
    Notes:This is the peer reviewed version of the following article: Seath, C. P., Fyfe, J. W. B., Molloy, J. J., & Watson, A. J. B. (2015). Tandem chemoselective Suzuki-Miyaura cross-coupling enabled by nucleophile speciation control. Angewandte Chemie, which has been published in final form at http://www.dx.doi.org/10.1002/ange.201504297. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Self-Archiving
    Keywords:boron, chemoselectivity, cross-coupling, palladium, speciation, Chemistry, Chemistry(all)
    Subjects:Science > Chemistry
    Department:Faculty of Science > Pure and Applied Chemistry
    Depositing user: Pure Administrator
    Date deposited:18 Jun 2015 15:09
    Last modified:25 Jan 2021 03:26
    Related URLs:
    URI:https://strathprints.strath.ac.uk/id/eprint/53425
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