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Humphreys, Philip G. and Anderson, Niall A. and Bamborough, Paul and Baxter, Andrew and Chung, Chun-wa and Cookson, Rosa and Craggs, Peter D. and Dalton, Toryn and Fournier, Julie C. L. and Gordon, Laurie J. and Gray, Heather F. and Gray, Matthew W. and Gregory, Richard and Hirst, David J. and Jamieson, Craig and Jones, Katherine L. and Kessedjian, Hripsimee and Lugo, David and McGonagle, Grant and Patel, Vipulkumar K. and Patten, Christopher and Poole, Darren L. and Prinjha, Rab K. and Ramirez-Molina, Cesar and Rioja, Inmaculada and Seal, Gail and Stafford, Kayleigh A. J. and Shah, Rishi R. and Tape, Daniel and Theodoulou, Natalie H. and Tomlinson, Laura R. and Ukuser, Sabri and Wall, Ian D. and Wellaway, Natalie and White, Gemma (2022) Identification and optimization of a ligand-efficient benzoazepinone bromodomain and extra terminal (BET) family acetyl-lysine mimetic into the oral candidate quality molecule I-BET432. Journal of Medicinal Chemistry, 65 (22). pp. 15174-15207. ISSN 0022-2623

Kay, Emily J and Paterson, Karla and Riera-Domingo, Carla and Sumpton, David and Däbritz, J. Henry M. and Tardito, Saverio and Boldrini, Claudia and Hernandez-Fernaud, Juan R. and Athineos, Dimitris and Dhayade, Sandeep and Stepanova, Ekaterina and Gjerga, Enio and Neilson, Lisa J. and Lilla, Sergio and Hedley, Ann and Koulouras, Grigorios and McGregor, Grace and Jamieson, Craig and Johnson, Radia Marie and Park, Morag and Kirschner, Kristina and Miller, Crispin and Kamphorst, Jurre J. and Loayza-Puch, Fabricio and Saez-Rodriguez, Julio and Mazzone, Massimiliano and Blyth, Karen and Zagnoni, Michele and Zanivan, Sara (2022) Author correction : Cancer-associated fibroblasts require proline synthesis by PYCR1 for the deposition of pro-tumorigenic extracellular matrix. Nature metabolism, 4 (8). p. 1084. ISSN 2522-5812

Booijink, Richell and Salgado-Polo, Fernando and Jamieson, Craig and Perrakis, Anastassis and Bansal, Ruchi (2022) A type IV Autotaxin inhibitor ameliorates acuteliver injury and nonalcoholic steatohepatitis. EMBO Molecular Medicine, 14 (9). e16333. ISSN 1757-4684

Kay, Emily J. and Paterson, Karla and Riero-Domingo, Carla and Sumpton, David and Däbritz, J. Henry M and Tardito, Saverio and Boldrini, Claudia and Hernandez-Fernaud, Juan R. and Athineos, Dimitris and Dhayade, Sandeep and Stepanova, Ekaterina and Gjerga, Enio and Neilson, Lisa J. and Lilla, Sergio and Hedley, Ann and Koulouras, Grigorios and McGregor, Grace and Jamieson, Craig and Johnson, Radia Marie and Park, Morag and Kirschner, Kristina and Miller, Crispin and Kamphorst, Jurre J. and Loayza-Puch, Fabricio and Saez-Rodriguez, Julio and Mazzone, Massimiliano and Blyth, Karen and Zagnoni, Michele and Zanivan, Sara (2022) Cancer-associated fibroblasts require proline synthesis by PYCR1 for the deposition of pro-tumorigenic extracellular matrix. Nature metabolism, 4 (6). pp. 693-710. ISSN 2522-5812

Clark, Jennifer M. and Salgado-Polo, Fernando and Macdonald, Simon J. F. and Barrett, Tim N. and Perrakis, Anastassis and Jamieson, Craig (2022) Structure-based design of a novel class of autotaxin inhibitors based on endogenous allosteric modulators. Journal of Medicinal Chemistry, 65 (8). 6338–6351. ISSN 0022-2623

Boyle, Mhairi and Livingstone, Keith and Henry, Martyn C. and Elwood, Jessica M. L. and Lopez Fernandez, J. Daniel and Jamieson, Craig (2022) Amide bond formation via the rearrangement of nitrile imines derived from N-2-nitrophenyl hydrazonyl bromides. Organic Letters, 24 (1). pp. 334-338. ISSN 1523-7060

2021

Milne, Kirsty and Henry, Martyn C. and Jamieson, Craig (2021) Synthesis of an allylic gem-difluoromethylene building block via radical-mediated difluorocyclopropane ring opening. Tetrahedron Letters, 81. 153344. ISSN 0040-4039

Livingstone, Keith and Little, Gemma and Jamieson, Craig (2021) Recent advances in the generation of nitrilium betaine 1,3-dipoles. Synthesis, 53 (14). pp. 2399-2407. ISSN 0039-7881

2020

Shaalan, Youssef and Boulton, Lee and Jamieson, Craig (2020) Ruthenium-catalyzed ester reductions applied to pharmaceutical intermediates. Organic Process Research and Development, 24 (11). pp. 2745-2751. ISSN 1083-6160

Green, Luke and Livingstone, Keith and Bertrand, Sophie and Peace, Simon and Jamieson, Craig (2020) UV-induced 1,3,4-oxadiazole formation from 5-substituted tetrazoles and carboxylic acids in flow. Chemistry - A European Journal, 26 (65). pp. 14866-14870. ISSN 1521-3765

Livingstone, Keith and Bertrand, Sophie and Kennedy, Alan R. and Jamieson, Craig (2020) Transition metal-free coupling of 1,3-dipoles and boronic acids as a sustainable approach to C-C bond formation. Chemistry - A European Journal, 26 (46). pp. 10591-10597. ISSN 1521-3765

Spencer, Jonathan A. and Baldwin, Ian R. and Barton, Nick and Chung, Chun-Wa and Convery, Máire A. and Edwards, Christopher D. and Jamieson, Craig and Mallett, David N. and Rowedder, James E. and Rowland, Paul and Thomas, Daniel A. and Hardy, Charlotte J. (2020) Design and development of a macrocyclic series targeting phosphoinositide 3-kinase δ. ACS Medicinal Chemistry Letters, 11 (7). pp. 1386-1391. ISSN 1948-5875

Livingstone, Keith and Bertrand, Sophie and Jamieson, Craig (2020) A one-pot Suzuki-hydrogenolysis protocol for the modular synthesis of 2,5-diaryltetrazoles. Journal of Organic Chemistry, 85 (11). pp. 7413-7423. ISSN 0022-3263

Watson, Morag E. and Scott, Daniel and Jamieson, Craig and Layfield, Robert and Mason, Andrew M. (2020) Design, synthesis and evaluation of E2-25K derived stapled peptides. Peptide Science. e24158. ISSN 2475-8817

2019

Livingstone, Keith and Tenberge, Marius and Pape, Felix and Daniliuc, Constantin G. and Jamieson, Craig and Gilmour, Ryan (2019) Photocatalytic E→Z Isomerization of β-Ionyl Derivatives. Organic Letters, 21 (23). pp. 9677-9680. ISSN 1523-7060

Livingstone, Keith and Betrand, Sophie and Mowat, Jenna and Jamieson, Craig (2019) Metal free C-C bond formation via coupling of nitrile imines and boronic acids. Chemical Science, 10 (44). pp. 10412-10416. ISSN 2041-6539

Milne, Kirsty and Sun, Jianhui and Zaal, Esther A. and Mowat, Jenna and Celie, Patrick H.N. and Fish, Alexander and Berkers, Celia R. and Forlani, Giuseppe and Loayza-Puch, Fabricio and Jamieson, Craig and Agami, Reuven (2019) A fragment-like approach to PYCR1 inhibition. Bioorganic and Medicinal Chemistry Letters, 29 (18). pp. 2626-2631. ISSN 0960-894X

Watson, Morag E. and Jamieson, Craig and Kennedy, Alan R. and Mason, Andrew M. (2019) A reappraisal of the Ni-[(Benzylprolyl)amino]benzophenone complex in the synthesis of α,α-disubstituted amino acid derivatives. Tetrahedron, 75 (36). 130485. ISSN 0040-4020

2018

McCarter, Adam W. and Sommer, Magdalana and Percy, Jonathan M. and Jamieson, Craig and Kennedy, Alan R. and Hirst, David J. (2018) Atom efficient synthesis of selectively difluorinated carbocycles through a gold(I) catalyzed cyclization. Journal of Organic Chemistry. ISSN 0022-3263

Wilson, Kirsty L. and Murray, Jane and Jamieson, Craig and Watson, Allan J. B. (2018) Cyrene as a bio-based solvent for HATU mediated amide coupling. Organic and Biomolecular Chemistry (16). pp. 2851-2854. ISSN 1477-0520

Littleson, Mairi M. and Baker, Christopher M. and Dalencon, Anne J. and Frye, Elizabeth C. and Jamieson, Craig and Kennedy, Alan R. and Ling, Kenneth B. and McLachlan, Matthew M. and Montgomery, Mark G. and Russell, Claire J. and Watson, Allan J. B. (2018) Scalable total synthesis and comprehensive structure–activity relationship studies of the phytotoxin coronatine. Nature Communications. ISSN 2041-1723 (In Press)

Buten, Christoph and Lamping, Sebastian and Korsgen, Martin and Arlinghaus, Henrich F. and Jamieson, Craig and Ravoo, Bart Jan (2018) Surface functionalization with carboxylic acids by photochemical microcontact printing and tetrazole chemistry. Langmuir. ISSN 0743-7463

2017

McPherson, Christopher G. and Cooper, Alasdair K. and Bubliauskas, Andrius and Mulrainey, Paul and Jamieson, Craig and Watson, Allan J. B. (2017) A multicomponent route to functionalized amides and oxazolidinones. Organic Letters. ISSN 1523-7060

Campbell, Peter S. and Jamieson, Craig and Simpson, Iain and Watson, Allan J. B. (2017) Practical synthesis of pharmaceutically relevant molecules enriched in sp3 character. Chemical Communications (London). ISSN 0009-241X

Spencer, Jonathan A. and Jamieson, Craig and Talbot, Eric P. A. (2017) One-pot, three-step synthesis of cyclopropylboronic acid pinacol esters from synthetically tractable propargylic silyl ethers. Organic Letters. ISSN 1523-7060

McPherson, Christopher G. and Caldwell, Nicola and Jamieson, Craig and Simpson, Iain and Watson, Allan J. B. (2017) Amidation of unactivated ester derivatives mediated by trifluoroethanol. Organic and Biomolecular Chemistry. ISSN 1477-0520

Keune, Willem-Jan and Potjewyd, Frances and Heidebrecht, Tatjana and Salgado-Polo, Fernando and Macdonald, Simon J. F. and Chelvarajan, Lakshman and Abdel Latif, Ahmed and Soman, Sony and Morris, Andrew J. and Watson, Allan J. B. and Jamieson, Craig and Perrakis, Anastassis (2017) Rational design of autotaxin inhibitors by structural evolution of endogenous modulators. Journal of Medicinal Chemistry, 60 (5). pp. 2006-2017. ISSN 0022-2623

Miller, Lisa M. and Pritchard, John M. and Macdonald, Simon J. F. and Jamieson, Craig and Watson, Allan J. B. (2017) Emergence of small molecule non-RGD-mimetic inhibitors for RGD integrins. Journal of Medicinal Chemistry, 60 (8). ISSN 0022-2623

Miller, Lisa M. and Keune, Willem-Jan and Castagna, Diana and Young, Louise C. and Duffy, Emma L. and Potjewyd, Frances and Salgado-Polo, Fernando and Garcia, Paloma Engel and Semaan, Dima and Pritchard, John M. and Perrakis, Anastassis and Macdonald, Simon J. F. and Jamieson, Craig and Watson, Allan J. B. (2017) Structure-activity relationships of small molecule autotaxin inhibitors with a discrete binding mode. Journal of Medicinal Chemistry, 60 (2). pp. 722-748. ISSN 0022-2623

2016

Measom, Nicholas and Down, Kenneth D. and Hirst, David J. and Jamieson, Craig and Manas, Eric S. and Patel, Vipulkumar K. and Somers, Donald O. (2016) Investigation of a bicyclo[1.1.1]pentane as a phenyl replacement within an LpPLA2 inhibitor. ACS Medicinal Chemistry Letters, 7.

Wilson, Kirsty and Kennedy, Alan and Murray, Jane and Greatex, Ben and Jamieson, Craig and Watson, Allan (2016) Scope and limitations of a DMF bio-alternative within Sonogashira cross-coupling and Cacchi-type annulation. Beilstein Journal of Organic Chemistry, 12. pp. 2005-2011. ISSN 1860-5397

Littleson, Mairi M. and Russell, Claire J. and Frye, Elizabeth C. and Ling, Kenneth B. and Jamieson, Craig and Watson, Allan J. B. (2016) Synthetic approaches to coronafacic acid, coronamic acid, and coronatine. Synthesis, 48. ISSN 0039-7881

Amour, Augustin and Barton, Nick and Cooper, Anthony W.J. and Inglis, Graham and Jamieson, Craig and Luscombe, Christopher N. and Perez, David and Peace, Simon and Rowland, Paul and Tame, Chris and Uddin, Sorif and Vitulli, Giovanni and Wellaway, Natalie (2016) Evolution of a novel orally bioavailable series of PI3Kδ inhibitors from an inhaled lead for the treatment of respiratory disease. Journal of Medicinal Chemistry. ISSN 0022-2623

Borthwick, Jennifer A. and Ancellin, Nicolas and Bertrand, Sophie M. and Bingham, Ryan P. and Carter, Paul S. and Chung, Chun-wa and Churcher, Ian and Dodic, Nerina and Fournier, Charlène and Francis, Peter L. and Hobbs, Andrew and Jamieson, Craig and Pickett, Stephen D. and Smith, Sarah E. and Somers, Donald O'N. and Spitzfaden, Claus and Suckling, Colin J. and Young, Robert J. (2016) Structurally diverse mitochondrial branched chain aminotransferase (BCATm) leads with varying binding modes identified by fragment screening. Journal of Medicinal Chemistry, 59 (6). pp. 2452-2467. ISSN 0022-2623

McPherson, Christopher G. and Livingstone, Keith and Jamieson, Craig and Simpson, Iain (2016) Palladium-catalyzed synthesis of aryl amides through silanoate-mediated hydrolysis of nitriles. Synlett, 27 (1). pp. 88-92. ISSN 0936-5214

2015

Bertrand, Sophie M. and Ancellin, Nicolas and Beaufils, Benjamin and Bingham, Ryan P. and Borthwick, Jennifer A. and Boullay, Anne Bénédicte and Boursier, Eric and Carter, Paul S. and Chung, Chun Wa and Churcher, Ian and Dodic, Nerina and Fouchet, Marie Hélène and Fournier, Charlène and Francis, Peter L. and Gummer, Laura A. and Herry, Kenny and Hobbs, Andrew and Hobbs, Clare I. and Homes, Paul and Jamieson, Craig and Nicodeme, Edwige and Pickett, Stephen D. and Reid, Iain H. and Simpson, Graham L. and Sloan, Lisa A. and Smith, Sarah E. and Somers, Donald O N and Spitzfaden, Claus and Suckling, Colin J. and Valko, Klara and Washio, Yoshiaki and Young, Robert J. (2015) The discovery of in vivo active mitochondrial branched-chain aminotransferase (BCATm) inhibitors by hybridizing fragment and HTS hits. Journal of Medicinal Chemistry, 58 (18). pp. 7140-7163. ISSN 0022-2623

Caldwell, Nicola and Jamieson, Craig and Simpson, Iain and Watson, Allan J B (2015) Catalytic amidation of unactivated ester derivatives mediated by trifluoroethanol. Chemical Communications, 51 (46). pp. 9495-9498. ISSN 1359-7345

Castagna, Diana and Duffy, Emma L. and Semaan, Dima and Young, Louise C. and Pritchard, John M. and Macdonald, Simon J. F. and Budd, David C. and Jamieson, Craig and Watson, Allan J. B. (2015) Identification of a novel class of autotaxin inhibitors through cross-screening. MedChemComm, 2015 (6). pp. 1149-1155. ISSN 2040-2503

Eastman, Harry E. and Jamieson, Craig and Watson, Allan J. B. (2015) Development of solvent selection guides. Aldrichimica Acta, 48 (2). pp. 51-55.

Caldwell, Nicola and Harms, Jonathan E. and Partin, Kathryn M. and Jamieson, Craig (2015) Rational design of a novel AMPA receptor modulator through a hybridization approach. ACS Medicinal Chemistry Letters.

2014

Caldwell, Nicola and Campbell, Peter S. and Jamieson, Craig and Potjewyd, Frances and Simpson, Iain and Watson, Allan J. B. (2014) Amidation of esters with amino alcohols using organobase catalysis. Journal of Organic Chemistry, 79 (19). pp. 9347-9354. ISSN 0022-3263

McGonagle, Fiona I. and Sneddon, Helen F. and Jamieson, Craig and Watson, Allan (2014) Molar efficiency : a useful metric to gauge relative reaction efficiency in discovery medicinal chemistry. ACS Sustainable Chemistry and Engineering, 2 (3). pp. 523-532. ISSN 2168-0485

Stewart, Sam and Harris, Robert and Jamieson, Craig (2014) Regiospecific synthesis of N2-aryl 1,2,3-triazoles from 2,5-disubstituted tetrazoles via photochemically generated nitrile imine intermediates. Synlett, 25 (17). pp. 2480-2484. ISSN 0936-5214

2013

Caldwell, Nicola and Jamieson, Craig and Simpson, Iain and Watson, Allan J. B. (2013) Development of a sustainable catalytic ester amidation process. ACS Sustainable Chemistry and Engineering, 1 (10). pp. 1339-1344.

Caldwell, Nicola and Jamieson, Craig and Simpson, Iain and Tuttle, Tell (2013) Organobase-catalyzed amidation of esters with amino alcohols. Organic Letters, 15 (10). pp. 2506-2509. ISSN 1523-7060

McGonagle, Fiona I. and MacMillan, Donna S. and Murray, Jane and Sneddon, Helen F. and Jamieson, Craig and Watson, Allan J. B. (2013) Development of a solvent selection guide for aldehyde-based direct reductive amination processes. Green Chemistry, 15 (5). pp. 1159-1165. ISSN 1463-9262

Harms, Jonathan E. and Benveniste, Morris and Maclean, John K.F. and Partin, Kathryn M. and Jamieson, Craig (2013) Functional analysis of a novel positive allosteric modulator of AMPA receptors derived from a structure-based drug design strategy. Neuropharmacology, 64. pp. 45-52. ISSN 0028-3908

MacMillan, Donna and Murray, J and Sneddon, Helen F. and Jamieson, Craig and Watson, Allan (2013) Evaluation of alternative solvents in common amide coupling reactions : replacement of dichloromethane and N,N-dimethylformamide. Green Chemistry, 15 (3). pp. 596-600. ISSN 1463-9262

2012

Jamieson, Craig and Morrow, John and Maclean, John; Albert, Jeffrey and Wood, Michael, eds. (2012) AMPA receptor positive modulators. In: Targets and Emerging Therapies for Schizophrenia. Wiley-VCH, Hoboken, NJ, pp. 187-231. ISBN 978-0-470-32282-6

MacMillan, Donna Stephanie and Murray, Jane and Sneddon, Helen F. and Jamieson, Craig and Watson, Allan (2012) Replacement of dichloromethane within chromatographic purification : a guide to alternative solvents. Green Chemistry, 14 (11). pp. 3016-3019. ISSN 1463-9262

2011

Jamieson, Craig and Maclean, John K.F. and Brown, Christopher I and Campbell, Robert A and Gillen, Kevin J. and Gillespie, Jonathan and Kazemier, Bert and Kiczun, Michael and LAMONT, YVONNE and Lyons, Amanda J. and Moir, Elizabeth M. and Morrow, John A. and Pantling, John and Rankovic, Zoran and Smith, Lynn (2011) Structure based evolution of a novel series of positive modulators of the AMPA receptor. Bioorganic and Medicinal Chemistry Letters, 21 (2). pp. 805-811. ISSN 0960-894X

2010

Grove, Simon J .A. and Jamieson, Craig and Maclean, John K. F. and Morrow, John A. and Rankovic, Zoran (2010) Positive allosteric modulators of the a-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptor. Journal of Medicinal Chemistry, 53 (20). pp. 7271-7279. ISSN 0022-2623

Jamieson, Craig and Campbell, Robert A. and Cumming, Iain A. and Gillen, Kevin J. and Gillespie, Jonathan and Kazemier, Bert and Kiczun, Michael and Lamont, Yvonne and Lyons, Amanda J. and Maclean, John K.F. and Martin, Frederic and Moir, Elizabeth M. and Morrow, John A. and Pantling, John and Rankovic, Zoran and Smith, Lynn (2010) A novel series of positive modulators of the AMPA receptor : structure-based lead optimization. Bioorganic and Medicinal Chemistry Letters, 20 (20). pp. 6072-6075. ISSN 0960-894X

Jamieson, Craig and Basten, Stephanie and Campbell, Robert A. and Cumming, Iain A. and Gillen, Kevin J. and Gillespie, Jonathan and Kazemier, Bert and Kiczun, Michael and Lamont, Yvonne and Lyons, Amanda J. and Maclean, John K.F. and Moir, Elizabeth M. and Morrow, John A. and Papakosta, Marianthi and Rankovic, Zoran and Smith, Lynn (2010) A novel series of positive modulators of the AMPA receptor : discovery and structure based hit-to-lead studies. Bioorganic and Medicinal Chemistry Letters, 20 (19). pp. 5753-5756. ISSN 0960-894X

Rankovic, Zoran and Cai, Jiaqiang and Fradera, Xavier and Dempster, Maureen and Mistry, Ashvin and Long, Clive and Hamilton, Emma and King, Angela and Boucharens, Sylviane and Jamieson, Craig and Gillespie, Jonathan and Cumming, Iain and Uitdehaag, Joost and van Zeeland, Mario. (2010) Dioxo-triazines as a novel series of cathepsin K inhibitors. Bioorganic and Medicinal Chemistry Letters, 20 (5). pp. 1488-1490. ISSN 0960-894X

Rankovic, Zoran and Jamieson, Craig and Morphy, Richard.; (2010) High throughput screening approach to lead discovery. In: Lead Generation Approaches in Drug Discovery. Wiley-VCH, Hoboken, NJ, pp. 21-71. ISBN 978-0-470-25761-6

2009

Sheldrake, Helen M and Jamieson, Craig and Pascu, Sofia I and Burton, Jonathan W (2009) Synthesis of the originally proposed structures of elatenyne and an enyne from Laurencia majuscula. Organic and Biomolecular Chemistry, 7 (2). pp. 238-252. ISSN 1477-0520

2008

Jamieson, Craig and Moir, Elizabeth M. and Rankovic, Zoran and Wishart, Grant.; Vaz, Roy J. and Klabunde, Thomas, eds. (2008) Strategy and tactics for hERG optimizations. In: Antitargets. Methods and Principles in Medicinal Chemistry, 38 . Wiley-VCH, Weinheim, Germany, pp. 423-455. ISBN 978-3-527-31821-6

This list was generated on Sat Dec 21 18:54:44 2024 GMT.

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