Strategy and tactics for hERG optimizations

Jamieson, Craig and Moir, Elizabeth M. and Rankovic, Zoran and Wishart, Grant.; Vaz, Roy J. and Klabunde, Thomas, eds. (2008) Strategy and tactics for hERG optimizations. In: Antitargets. Methods and Principles in Medicinal Chemistry, 38 . Wiley-VCH, Weinheim, Germany, pp. 423-455. ISBN 978-3-527-31821-6 (https://doi.org/10.1002/9783527621460.ch18)

Abstract

A review on the approaches used to circumvent activity at human ether-a-go-go related gene (hERG), identified through an extensive survey of the medicinal chem. literature until the end of 2006. [on SciFinder(R)]

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• Item metadata

  Item type:	Book Section
  ID code:	33979
  Dates:	Date Event January 2008 Published
  Notes:	M1 - Copyright (C) 2011 American Chemical Society (ACS). All Rights Reserved. CAPLUS AN 2008:610211(Journal; General Review)
  Subjects:	Science > Chemistry
  Department:	Faculty of Science > Pure and Applied Chemistry
  Depositing user:	Pure Administrator
  Date deposited:	29 Sep 2011 18:50
  Last modified:	08 Apr 2024 12:48
  URI:	https://strathprints.strath.ac.uk/id/eprint/33979