Regiospecific synthesis of N2-aryl 1,2,3-triazoles from 2,5-disubstituted tetrazoles via photochemically generated nitrile imine intermediates

Stewart, Sam and Harris, Robert and Jamieson, Craig (2014) Regiospecific synthesis of N2-aryl 1,2,3-triazoles from 2,5-disubstituted tetrazoles via photochemically generated nitrile imine intermediates. Synlett, 25 (17). pp. 2480-2484. ISSN 0936-5214

[img]
Preview
 PDF (Stewart-etal-Synlett-2015-Regiospecific-synthesis-of-N2-aryl)
Stewart_etal_Synlett_2015_Regiospecific_synthesis_of_N2_aryl.pdf
Accepted Author Manuscript
Download (353kB)| Preview

    Abstract

    The synthesis of N2-aryl 1,2,3-triazoles from 2,5-disubstituted tetrazoles was achieved under photochemical conditions. This simple and mild one-step reaction provides regiospecific access to 2,4,5-substituted 1,2,3-triazoles via a nitrile imine intermediate. Syntheses of alkyl and heterocylic derivatives were also investigated.

    Creators(s): Stewart, Sam ORCID logoORCID: https://orcid.org/0000-0003-3674-5349, Harris, Robert and Jamieson, Craig ORCID logoORCID: https://orcid.org/0000-0002-6567-8272;
    Item type:Article
    ID code:51137
    Keywords:photochemistry, regioselectivity, tetrazole, triazole, indazole, Chemistry, Organic Chemistry
    Subjects:Science > Chemistry
    Department:Faculty of Science > Pure and Applied Chemistry
    Depositing user: Pure Administrator
    Date deposited:16 Jan 2015 14:53
    Last modified:20 Jan 2021 21:45
    Related URLs:
    URI:https://strathprints.strath.ac.uk/id/eprint/51137
    Export data:
    CORE (COnnecting REpositories)