UV-induced 1,3,4-oxadiazole formation from 5-substituted tetrazoles and carboxylic acids in flow

Green, Luke and Livingstone, Keith and Bertrand, Sophie and Peace, Simon and Jamieson, Craig (2020) UV-induced 1,3,4-oxadiazole formation from 5-substituted tetrazoles and carboxylic acids in flow. Chemistry - A European Journal, 26 (65). pp. 14866-14870. ISSN 0947-6539 (https://doi.org/10.1002/chem.202002896)

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Abstract

A range of 1,3,4-oxadiazoles have been synthesized using a UV-B activated flow approach starting from carboxylic acids and 5-substituted tetrazoles. The application of UV light represents an attractive alternative to the traditional thermolytic approach and has demonstrated comparable efficiency and versatility, with a diverse substrate scope, including the incorporation of highly substituted amino acids.

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• Item metadata

  Item type:	Article
  ID code:	73628
  Dates:	Date Event 20 November 2020 Published 12 August 2020 Published Online 12 August 2020 Accepted
  Subjects:	Science > Chemistry
  Department:	Faculty of Science > Pure and Applied Chemistry Strategic Research Themes > Health and Wellbeing
  Depositing user:	Pure Administrator
  Date deposited:	14 Aug 2020 13:16
  Last modified:	20 Apr 2024 00:42
  URI:	https://strathprints.strath.ac.uk/id/eprint/73628