A one-pot Suzuki-hydrogenolysis protocol for the modular synthesis of 2,5-diaryltetrazoles

Livingstone, Keith and Bertrand, Sophie and Jamieson, Craig (2020) A one-pot Suzuki-hydrogenolysis protocol for the modular synthesis of 2,5-diaryltetrazoles. Journal of Organic Chemistry, 85 (11). pp. 7413-7423. ISSN 0022-3263

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    Abstract

    2,5-Diaryltetrazoles are a diverse range of compounds of considerable interest within the field of photochemistry as a valuable precursor of the nitrile imine 1,3-dipole. Current literature approaches toward this heterocycle remain unsuitable for the practical synthesis of a library of these derivatives. Herein, we disclose the development of a modular approach toward 2,5-diaryltetrazoles compatible with an array-type protocol, facilitated by a tandem Suzuki-hydrogenolysis approach.

    Creators(s): Livingstone, Keith, Bertrand, Sophie and Jamieson, Craig ORCID logoORCID: https://orcid.org/0000-0002-6567-8272;
    Item type:Article
    ID code:72479
    Keywords:2,5-diaryltetrazoles, photochemistry, modular approach, Chemistry, Organic Chemistry
    Subjects:Science > Chemistry
    Department:Strategic Research Themes > Health and Wellbeing
    Faculty of Science > Pure and Applied Chemistry
    Depositing user: Pure Administrator
    Date deposited:27 May 2020 12:26
    Last modified:08 Sep 2020 04:14
    URI:https://strathprints.strath.ac.uk/id/eprint/72479
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