Strategies towards chemoselective suzuki-miyaura cross-coupling

Fyfe, James W. B. and Watson, Allan J. B. (2015) Strategies towards chemoselective suzuki-miyaura cross-coupling. Synlett, 26 (9). pp. 1139-1144. ISSN 0936-5214

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    Abstract

    Chemoselective Suzuki-Miyaura cross-coupling has emerged as a powerful method for the rapid preparation of sp2-and sp3-hybridized carbon frameworks based on control of the oxidative addition or transmetallation events. The field of chemoselective transmetallation has recently seen considerable development with several different strategies emerging including protected boronic acids, neighboring group activation, and chemoselective speciation. Herein, these state-of-the-art approaches towards chemoselective Suzuki-Miyaura cross-coupling are highlighted.